PT815074E - Compostos de o-carbamoil-(d)-fenilalanilol e processo para a sua preparacao - Google Patents
Compostos de o-carbamoil-(d)-fenilalanilol e processo para a sua preparacaoInfo
- Publication number
- PT815074E PT815074E PT96901562T PT96901562T PT815074E PT 815074 E PT815074 E PT 815074E PT 96901562 T PT96901562 T PT 96901562T PT 96901562 T PT96901562 T PT 96901562T PT 815074 E PT815074 E PT 815074E
- Authority
- PT
- Portugal
- Prior art keywords
- fenylalanylol
- carbamoyl
- compounds
- preparation
- fenylalanylol compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019950002543A KR0173862B1 (ko) | 1995-02-11 | 1995-02-11 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT815074E true PT815074E (pt) | 2002-03-28 |
Family
ID=19408007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96901562T PT815074E (pt) | 1995-02-11 | 1996-02-08 | Compostos de o-carbamoil-(d)-fenilalanilol e processo para a sua preparacao |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5705640C1 (pt) |
| EP (1) | EP0815074B1 (pt) |
| JP (1) | JP3828574B2 (pt) |
| KR (1) | KR0173862B1 (pt) |
| CN (1) | CN1070846C (pt) |
| CA (1) | CA2212326C (pt) |
| DE (1) | DE69615668T2 (pt) |
| DK (1) | DK0815074T3 (pt) |
| ES (1) | ES2165485T3 (pt) |
| PT (1) | PT815074E (pt) |
| WO (1) | WO1996024577A1 (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0173863B1 (ko) * | 1995-04-10 | 1999-04-01 | 조규향 | 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| WO1998015526A1 (en) * | 1996-10-10 | 1998-04-16 | Sk Corporation | O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same |
| AU2005302589B2 (en) * | 2004-10-28 | 2010-09-16 | Sk Biopharmaceuticals Co., Ltd. | Adjunctive therapy for depression |
| US8440715B2 (en) * | 2005-06-08 | 2013-05-14 | Sk Biopharmaceuticals Co., Ltd. | Treatment of sleep-wake disorders |
| WO2007001841A1 (en) * | 2005-06-22 | 2007-01-04 | Sk Holdings Co., Ltd. | Treatment of sexual dysfunction |
| EA200970377A1 (ru) * | 2006-10-13 | 2009-10-30 | Янссен Фармацевтика Нв | Композиции фенилалкиламинокарбамата |
| US8642772B2 (en) * | 2008-10-14 | 2014-02-04 | Sk Biopharmaceuticals Co., Ltd. | Piperidine compounds, pharmaceutical composition comprising the same and its use |
| KR102021075B1 (ko) | 2009-06-22 | 2019-11-04 | 에스케이바이오팜 주식회사 | 피로의 치료 또는 예방 방법 |
| US8232315B2 (en) * | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| KR101783632B1 (ko) | 2009-11-06 | 2017-10-10 | 에스케이바이오팜 주식회사 | 주의력 결핍/과잉행동 장애(ａｄｈｄ)의 치료 방법 |
| US8927602B2 (en) | 2009-11-06 | 2015-01-06 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| HRP20221018T1 (hr) | 2013-03-13 | 2023-01-06 | Jazz Pharmaceuticals Ireland Limited | Liječenje katapleksije |
| ES2812586T3 (es) | 2013-07-18 | 2021-03-17 | Jazz Pharmaceuticals Ireland Ltd | Tratamiento para la obesidad |
| TWI698415B (zh) * | 2014-02-28 | 2020-07-11 | 南韓商愛思開生物製藥股份有限公司 | 胺基羰基胺基甲酸酯化合物 |
| US10888542B2 (en) | 2014-02-28 | 2021-01-12 | Sk Biopharmaceuticals Co., Ltd. | Aminocarbonylcarbamate compounds |
| CN109996540A (zh) | 2016-09-06 | 2019-07-09 | 爵士制药国际Iii有限公司 | (r)-2-氨基-3-苯丙基氨基甲酸酯的溶剂化物形式 |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| ES2964943T3 (es) | 2016-10-06 | 2024-04-10 | Axsome Malta Ltd | Compuestos de carbamoilfenilalaninol para uso médico |
| MY203401A (en) | 2017-06-02 | 2024-06-26 | Jazz Pharmaceuticals Ireland Ltd | Methods and compositions for treating excessive sleepiness |
| US11413264B2 (en) | 2017-07-31 | 2022-08-16 | Jazz Pharmaceuticals Ireland Limited | Carbamoyl phenylalaninol analogs and uses thereof |
| CN110655500B (zh) * | 2018-06-28 | 2020-12-08 | 浙江京新药业股份有限公司 | 氨基甲酸酯衍生物及其制备方法和用途 |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
| KR102390194B1 (ko) | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
| KR20240101826A (ko) * | 2021-11-16 | 2024-07-02 | 액섬 몰타 엘티디. | 인지 장애를 치료하기 위한 방법 및 조성물 |
| AU2024278948A1 (en) | 2023-05-30 | 2025-12-11 | Axsome Therapeutics, Inc. | Solriamfetol for treating cognitive impairment in a subject with impaired cognition associated with obstructive sleep apnea and excessive daytime sleepiness |
| WO2025006965A1 (en) | 2023-06-29 | 2025-01-02 | Axsome Therapeutics, Inc. | Methods of administering solriamfetol to lactating women |
| WO2025042959A1 (en) | 2023-08-21 | 2025-02-27 | Axsome Therapeutics, Inc. | Use of solriamfetol for the treatment of orphan diseases |
| WO2025165760A1 (en) | 2024-01-29 | 2025-08-07 | Axsome Therapeutics, Inc. | Phenylalkylamino carbamates for use in the treatment of attention deficit/hyperactivity disorder |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470277A1 (de) * | 1963-04-18 | 1969-05-29 | Siegfried Ag | Verfahren zur Herstellung von spasmolytische und tremolytische Eigenschaften aufweisenden Carbaminaten |
| FR8411M (pt) * | 1968-12-31 | 1971-03-31 | ||
| AT387572B (de) * | 1983-05-20 | 1989-02-10 | Ferrosan Ab | Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden |
| KR100197892B1 (ko) * | 1994-09-09 | 1999-06-15 | 남창우 | 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법 |
-
1995
- 1995-02-11 KR KR1019950002543A patent/KR0173862B1/ko not_active Expired - Lifetime
-
1996
- 1996-02-05 US US08596496 patent/US5705640C1/en not_active Expired - Lifetime
- 1996-02-08 DK DK96901562T patent/DK0815074T3/da active
- 1996-02-08 CN CN96191875A patent/CN1070846C/zh not_active Expired - Lifetime
- 1996-02-08 CA CA002212326A patent/CA2212326C/en not_active Expired - Lifetime
- 1996-02-08 DE DE69615668T patent/DE69615668T2/de not_active Expired - Lifetime
- 1996-02-08 EP EP96901562A patent/EP0815074B1/en not_active Expired - Lifetime
- 1996-02-08 WO PCT/KR1996/000018 patent/WO1996024577A1/en not_active Ceased
- 1996-02-08 PT PT96901562T patent/PT815074E/pt unknown
- 1996-02-08 ES ES96901562T patent/ES2165485T3/es not_active Expired - Lifetime
- 1996-02-08 JP JP52415596A patent/JP3828574B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR0173862B1 (ko) | 1999-04-01 |
| CN1070846C (zh) | 2001-09-12 |
| CA2212326A1 (en) | 1996-08-15 |
| ES2165485T3 (es) | 2002-03-16 |
| JP3828574B2 (ja) | 2006-10-04 |
| JPH11501617A (ja) | 1999-02-09 |
| WO1996024577A1 (en) | 1996-08-15 |
| DE69615668T2 (de) | 2002-07-11 |
| CN1173863A (zh) | 1998-02-18 |
| EP0815074A1 (en) | 1998-01-07 |
| DE69615668D1 (de) | 2001-11-08 |
| CA2212326C (en) | 2008-12-23 |
| US5705640C1 (en) | 2001-03-20 |
| KR960031427A (ko) | 1996-09-17 |
| EP0815074B1 (en) | 2001-10-04 |
| US5705640A (en) | 1998-01-06 |
| DK0815074T3 (da) | 2002-01-28 |
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