PT808172E - Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular - Google Patents
Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricularInfo
- Publication number
- PT808172E PT808172E PT96910309T PT96910309T PT808172E PT 808172 E PT808172 E PT 808172E PT 96910309 T PT96910309 T PT 96910309T PT 96910309 T PT96910309 T PT 96910309T PT 808172 E PT808172 E PT 808172E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- inhibitor
- angiotensin
- conversation
- combination
- Prior art date
Links
- 229940083712 aldosterone antagonist Drugs 0.000 title abstract 2
- 239000002170 aldosterone antagonist Substances 0.000 title abstract 2
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 206010047295 Ventricular hypertrophy Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 108010061435 Enalapril Proteins 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 208000002682 Hyperkalemia Diseases 0.000 abstract 1
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 abstract 1
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 229960000830 captopril Drugs 0.000 abstract 1
- FAKRSMQSSFJEIM-RQJHMYQMSA-N captopril Chemical compound SC[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O FAKRSMQSSFJEIM-RQJHMYQMSA-N 0.000 abstract 1
- 238000011262 co‐therapy Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960000873 enalapril Drugs 0.000 abstract 1
- GBXSMTUPTTWBMN-XIRDDKMYSA-N enalapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229960002256 spironolactone Drugs 0.000 abstract 1
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38685295A | 1995-02-10 | 1995-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT808172E true PT808172E (pt) | 2003-11-28 |
Family
ID=23527334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96910309T PT808172E (pt) | 1995-02-10 | 1996-02-09 | Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP0808172B1 (pt) |
| JP (1) | JPH11507012A (pt) |
| KR (1) | KR19980702099A (pt) |
| AT (1) | ATE243529T1 (pt) |
| AU (1) | AU5354196A (pt) |
| BR (1) | BR9604882A (pt) |
| CA (1) | CA2212713A1 (pt) |
| DE (1) | DE69628821T2 (pt) |
| DK (1) | DK0808172T3 (pt) |
| ES (1) | ES2205023T3 (pt) |
| NZ (1) | NZ305528A (pt) |
| PT (1) | PT808172E (pt) |
| WO (1) | WO1996024373A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69808518T2 (de) * | 1997-12-23 | 2003-06-26 | Warner-Lambert Co., Morris Plains | Ace hemmer/matrix metalloproteinase hemmer-arzneimittelkombinationen |
| EP1121111B1 (en) * | 1998-10-15 | 2010-02-10 | Imperial Innovations Limited | Compounds for the treatment of weight loss |
| KR20010100986A (ko) | 1998-11-06 | 2001-11-14 | 로저 에이. 윌리암스 | 심장혈관 질병으로 인한 이병률 및 사망률 감소용안지오텐신 전환 효소 억제제 및 알도스테론 길항제의결합 치료방법 |
| SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| NZ517468A (en) | 1999-08-30 | 2004-02-27 | Aventis Pharma Gmbh | Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events |
| AU2001255730A1 (en) * | 2000-04-26 | 2001-11-07 | First Horizon Pharmaceutical Corporation | Methods and compositions for the treatment of cardiac indications |
| US20050014732A1 (en) * | 2003-03-14 | 2005-01-20 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and an anti-diabetic agent |
| CL2004000544A1 (es) * | 2003-03-18 | 2005-01-28 | Pharmacia Corp Sa Organizada B | Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati |
| CN106018820B (zh) * | 2006-08-04 | 2018-04-27 | 汉诺威医学院 | 根据gdf-15评价心脏介入风险的工具与方法 |
| FR2917975B1 (fr) * | 2007-06-26 | 2009-10-16 | Ceva Sante Animale Sa | Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains |
| ES2836508T3 (es) * | 2009-03-26 | 2021-06-25 | Ajay Gupta | Composiciones y métodos para el tratamiento de la enfermedad renal |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217347A (en) * | 1977-12-27 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Method of treating hypertension and medicaments therefor |
| WO1995009625A1 (en) * | 1993-10-04 | 1995-04-13 | Handforth Investments Ltd. | Use of amiodarone for the treatment of heart failure |
-
1996
- 1996-02-09 CA CA002212713A patent/CA2212713A1/en not_active Abandoned
- 1996-02-09 AU AU53541/96A patent/AU5354196A/en not_active Abandoned
- 1996-02-09 BR BR9604882A patent/BR9604882A/pt not_active Application Discontinuation
- 1996-02-09 DK DK96910309T patent/DK0808172T3/da active
- 1996-02-09 DE DE69628821T patent/DE69628821T2/de not_active Expired - Fee Related
- 1996-02-09 ES ES96910309T patent/ES2205023T3/es not_active Expired - Lifetime
- 1996-02-09 EP EP96910309A patent/EP0808172B1/en not_active Expired - Lifetime
- 1996-02-09 EP EP01116593A patent/EP1136078A3/en not_active Withdrawn
- 1996-02-09 NZ NZ305528A patent/NZ305528A/en unknown
- 1996-02-09 PT PT96910309T patent/PT808172E/pt unknown
- 1996-02-09 KR KR1019970705494A patent/KR19980702099A/ko not_active Ceased
- 1996-02-09 AT AT96910309T patent/ATE243529T1/de not_active IP Right Cessation
- 1996-02-09 WO PCT/US1996/001969 patent/WO1996024373A2/en not_active Ceased
- 1996-02-09 JP JP8524487A patent/JPH11507012A/ja not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2212713A1 (en) | 1996-08-15 |
| AU5354196A (en) | 1996-08-27 |
| NZ305528A (en) | 2001-05-25 |
| EP1136078A3 (en) | 2002-07-24 |
| WO1996024373A3 (en) | 1996-09-26 |
| DK0808172T3 (da) | 2003-10-20 |
| JPH11507012A (ja) | 1999-06-22 |
| EP1136078A2 (en) | 2001-09-26 |
| DE69628821D1 (de) | 2003-07-31 |
| BR9604882A (pt) | 1998-05-19 |
| EP0808172A2 (en) | 1997-11-26 |
| KR19980702099A (ko) | 1998-07-15 |
| ATE243529T1 (de) | 2003-07-15 |
| EP0808172B1 (en) | 2003-06-25 |
| ES2205023T3 (es) | 2004-05-01 |
| DE69628821T2 (de) | 2004-05-06 |
| WO1996024373A2 (en) | 1996-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9915134A (pt) | Co-terapia e terapia combinada para o tratamento de distúrbio cardiovascular em um indivìduo, e, composição | |
| MY121008A (en) | Combination therapy comprising atorvastatin and an antihypertensive agent. | |
| WO2004030627A3 (en) | Synergistic methods and compositions for treating cancer | |
| AU2592600A (en) | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia | |
| MXPA05000832A (es) | Metodos de diagnosticar y tratar pre-eclampsia o eclampsia. | |
| GB9700396D0 (en) | Photochemotherapeutic compositions | |
| WO1997044063A3 (en) | Dha-pharmaceutical agent conjugates | |
| NZ332720A (en) | Therapeutic uses of bactericidal/permeability increasing (BPI) protein to treat human meningococcemia | |
| PT808172E (pt) | Combinacao de inibidor da enzima de conversao da angiotensina e de antagonista de aldosterona para o tratamento de hipertrofia ventricular | |
| MXPA00007388A (es) | Metodos para tratar la pigmentacion de la piel. | |
| NZ332721A (en) | Use of bactericidal/permeability increasing (BPI) protein sometimes in conjunction with a thrombolytic agent to treat thrombotic disorders | |
| TR199901703T2 (xx) | Siklooksijenaz-2 inhibit�rlerini anti-anjiyojenik ajanlar olarak kullanma y�ntemi. | |
| MXPA01009035A (es) | Terapia de combinacion de inhibidor de enzima convertidora de angiotensina y antagonista de aldosterona epoxi-esteroidea para tratamiento de enfermedad cardiovascular. | |
| AU5774699A (en) | Human stearoyl-coa desaturase-related compositions and methods for treating skin disorders | |
| UA50761C2 (uk) | Спосіб запобігання та/або лікування серцевих захворювань, фармацевтична композиція та спосіб запобігання та/або лікування серцевої недостатності та дисфункції шлуночків в організмі теплокровної тварини | |
| AU2001282990A1 (en) | Aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy to prevent or treat inflammation-related cardiovascular disorders | |
| WO1996024372A3 (en) | Combination of angiotensin converting enzyme inhibitor, side-effect-reduced amount of aldosterone antagonist and diuretic | |
| DE60109594D1 (de) | R-eliprodil zur behandlung von glaucoma | |
| WO2004030623A3 (en) | Nitroxide radioprotector formulations and methods of use | |
| LT2001045A (en) | Compositions and use thereof for downmodulating the immune response to therapeutic proteins | |
| DK0956038T3 (da) | Morfogen peptidinduceret regeneration af senseopfattelsesvæv | |
| PL373391A1 (en) | Aldosterone blocker therapy to prevent or treat inflammation-related disorders | |
| WO2001046405A3 (en) | Modulation of pax-2 for controlled apoptosis or survival of cells | |
| EP1859796A3 (en) | Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors | |
| PL365075A1 (en) | Combinations of dalfopristine/quinupristine with cefpirome |