[go: up one dir, main page]

CL2004000544A1 - Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati - Google Patents

Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati

Info

Publication number
CL2004000544A1
CL2004000544A1 CL200400544A CL2004000544A CL2004000544A1 CL 2004000544 A1 CL2004000544 A1 CL 2004000544A1 CL 200400544 A CL200400544 A CL 200400544A CL 2004000544 A CL2004000544 A CL 2004000544A CL 2004000544 A1 CL2004000544 A1 CL 2004000544A1
Authority
CL
Chile
Prior art keywords
hypertension
insulinopati
algosterone
prevention
useful
Prior art date
Application number
CL200400544A
Other languages
English (en)
Inventor
G Mcmahon Amy E Rudolph Ellen
Original Assignee
Pharmacia Corp Sa Organizada B
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp Sa Organizada B filed Critical Pharmacia Corp Sa Organizada B
Publication of CL2004000544A1 publication Critical patent/CL2004000544A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

USO DE UNA COMBINACION DE UNO O MAS ANTAGONISTAS DE RECEPTORES DE LA ALDOSTERONA Y UNO O MAS INHIBIDORES DE LA EPN, UNA COMBINACION DE UNO O MAS ANTAGONISTAS DE RECEPTORES DE LA ALDOSTERONA, UNO O MAS INHIBIDORES DE LA EPN, Y UNO O MAS INHIBIDORES DE LA ECA, O UNA COMBINACION DE UNO O MAS ANTAGONISTAS DE RECEPTORES DE LA ALDOSTERONA Y UNO O MAS INHIBIDORES DE LA VASOPEPTIDASA PARA EL TRATAMIENTO TERAPEUTICO Y/O PROFILAXIS DE UNA CONDICION DE HIPERTENSION, ENFERMEDAD CARDIOVASCULAR, DISFUNCION RENAL, EDEMA, ENFERMEDAD CEREBROVASCULAR, O CONDICION PATOLOGICA DE INSULINOPATIA EN UN SUJETO.
CL200400544A 2003-03-18 2004-03-17 Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati CL2004000544A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45573803P 2003-03-18 2003-03-18

Publications (1)

Publication Number Publication Date
CL2004000544A1 true CL2004000544A1 (es) 2005-01-28

Family

ID=33030050

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200400544A CL2004000544A1 (es) 2003-03-18 2004-03-17 Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati

Country Status (4)

Country Link
US (1) US20040192584A1 (es)
CL (1) CL2004000544A1 (es)
TW (1) TW200507855A (es)
WO (1) WO2004082636A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393652B2 (en) 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
JP2007525165A (ja) 2003-03-07 2007-09-06 トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク タイプ１ライアノジン受容体に基づく方法
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
BRPI0518829A2 (pt) 2004-12-06 2008-12-09 Avigen Inc mÉtodo para o tratamento de dor neuropÁtica e sÍndromes associadas
JP2008524159A (ja) * 2004-12-15 2008-07-10 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング ＮＥＰ阻害剤、内因性エンドセリン産生系の阻害剤およびＨＭＧＣｏＡレダクターゼ阻害剤を含有する医薬組成物
MY146830A (en) * 2005-02-11 2012-09-28 Novartis Ag Combination of organic compounds
CA2596922A1 (en) * 2005-02-18 2006-08-24 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics
US20060205625A1 (en) * 2005-02-18 2006-09-14 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
WO2007051007A2 (en) * 2005-10-28 2007-05-03 Novartis Ag Combination of antihypertensives with cholesterol-lowering agent
US20080181876A1 (en) * 2007-01-30 2008-07-31 Johnson Kirk W Methods for treating acute and subchronic pain
US20080287402A1 (en) * 2007-05-03 2008-11-20 Johnson Kirk W Use of a glial attenuator to prevent amplified pain responses caused by glial priming
WO2017006254A1 (en) * 2015-07-08 2017-01-12 Novartis Ag Drug combination comprising an angiotensin ii receptor antagonist, a neutral endopeptidase inhibitor and a mineralcorticoid receptor antagonist
WO2017029261A1 (de) * 2015-08-19 2017-02-23 Bayer Pharma Aktiengesellschaft Kombinationspräparat umfassend finerenone und einen nep-inhibitor (sacubitril)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4508729A (en) * 1979-12-07 1985-04-02 Adir Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
CA1341296C (en) * 1981-12-29 2001-09-25 Hansjorg Urbach 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use
US4555502A (en) * 1982-09-30 1985-11-26 Merck & Co., Inc. Aminoacyl-containing dipeptide derivatives useful as antihypertensives
US4559332A (en) * 1983-04-13 1985-12-17 Ciba Geigy Corporation 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof
US5192800A (en) * 1986-12-11 1993-03-09 Pfizer Inc. Glutaramide diuretic agents
US5552397A (en) * 1992-05-18 1996-09-03 E. R. Squibb & Sons, Inc. Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
ATE130292T1 (de) * 1993-09-22 1995-12-15 Pfizer Res & Dev Hydrierung.
DE69628821T2 (de) * 1995-02-10 2004-05-06 G.D. Searle & Co., Skokie Kombination von ace-hemmern mit aldosteronantagonisten zur behandlung der ventrikulären hypertrophie
DE19750002A1 (de) * 1997-11-12 1999-05-20 Solvay Pharm Gmbh Phosphonsäure-substituierte Benzazepinon-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
US20040192584A1 (en) 2004-09-30
WO2004082636A2 (en) 2004-09-30
WO2004082636A3 (en) 2005-12-29
TW200507855A (en) 2005-03-01

Similar Documents

Publication Publication Date Title
CL2004000544A1 (es) Uso de una combinacion farmaceutica, de un antagonista del receptor de aldosterona y un inhibidor de endopeptidasa neutral, util para el tratamiento y prevencion de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopati
ECSP14019136A (es) Combinaciones farmacéuticas de un antagonista del receptor de angiotensina y un inhibidor de endopeptidasa neutra (nep)
CL2004000545A1 (es) Uso de un antagonista de los receptores de aldosterona y un antagonista de receptores de endotelina para el tratamiento o profilaxis de una condicion patologica relacionada con hipertension, disfuncion renal, insulinopatia y enfermedades cardiovascul
WO2004100871A3 (en) Combination of an aldosterone receptor antagonist and a renin inhibitor
EA200870029A1 (ru) Способ применения антагонистов il-6 с ингибиторами протеасом
AR037065A1 (es) Una composicion farmaceutica en base a bloqueadores de receptores 5ht3 y 5ht4, inhibidores de la bomba de protones y antagonistas de receptores de h2, util para tratar los desordenes gastrointestinales
DE602007006961D1 (de) Cgrp-rezeptorantagonisten
DOP2022000277A (es) Antagonista del receptor crf1 para el tratamiento de la hiperplasia suprarrenal congénita
ECSP066468A (es) Antagonistas de receptores muscarínicos de acetilcolina
GT201000131A (es) Composiciones farmaceuticas de accion doble basadas en super-estructuras de antagonista/ bloqueador del receptor de angiotensina (arb) e inhibidor de endopeptidasa neutra (nep)
EP1786931A4 (en) METHOD AND COMPOSITIONS FOR MEASURING NATURURETIC PEPTIDES AND USE THEREOF
EA200901646A1 (ru) Ингибиторы рецепторных тирозинкиназ и их применение
TW200730202A (en) Solid dosage form
MY150758A (en) Bilayer tablet comprising telmisartan and amlodipine
UY28766A1 (es) Compuestos heteropolicíclicos adicionales y su uso como antagonistas del receptor de glutamato metabotrópico
UA112514C2 (uk) АНТАГОНІСТИ C5aR
ECSP088131A (es) Asociación de un agente hipnótico de duración de acción larga y un agente hipnótico de duración de acción corta y su aplicación en terapéutica
EA200400879A1 (ru) Двухслойная фармацевтическая таблетка, содержащая телмисартан и диуретик, и её получение
EA200802381A1 (ru) Лечение желудочно-кишечных расстройств антагонистами cgrp-пептида
EA200100937A1 (ru) Способы и композиции, использующие (-)-норцисаприд в комбинации с ингибиторами протонных насосов или антагонистами h2-рецепторов
SG163564A1 (en) Kinin antagonists for treating bladder dysfunction
CL2021001884A1 (es) Compuestos heterocíclicos como antagonistas de la adenosina.
EP1765805A4 (en) CGRP RECEPTOR ANTAGONISTS
DK1313485T3 (da) Anvendelse af en aldosteronreceptorantagonist til forbedring af kognitiv funktion
ATE390148T1 (de) Pharmazeutische zusammensetzung mit einem selektiven i1 imidazolin-rezeptor-agonisten und einem angiotensin-ii-rezeptorblocker