PT4421069T - Compostos e composições para modular atividades da cinase do egfr mutante - Google Patents

Compostos e composições para modular atividades da cinase do egfr mutante

Info

Publication number: PT4421069T
Authority: PT; Portugal
Prior art keywords: compositions; compounds; kinase activities; egfr mutant; mutant kinase
Prior art date: 2014-10-13

Application number

PT241669472T

Other languages

English (en)

Original Assignee

Yuhan Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-10-13

Filing date

2015-10-13

Publication date

2026-01-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55654993&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT4421069(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-10-13 Application filed by Yuhan Corp filed Critical Yuhan Corp

2026-01-12 Publication of PT4421069T publication Critical patent/PT4421069T/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quick-Acting Or Multi-Walled Pipe Joints (AREA)

PT241669472T 2014-10-13 2015-10-13 Compostos e composições para modular atividades da cinase do egfr mutante PT4421069T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201462063394P	2014-10-13	2014-10-13

Publications (1)

Publication Number	Publication Date
PT4421069T true PT4421069T (pt)	2026-01-12

Family

ID=55654993

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
PT211716196T PT3929190T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular atividades da cinase do mutante de egfr
PT191967132T PT3604294T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular atividades da cinase do mutante de egfr
PT158503144T PT3207035T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular actividades da cinase do mutante de egfr
PT241669472T PT4421069T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular atividades da cinase do egfr mutante

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
PT211716196T PT3929190T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular atividades da cinase do mutante de egfr
PT191967132T PT3604294T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular atividades da cinase do mutante de egfr
PT158503144T PT3207035T (pt)	2014-10-13	2015-10-13	Compostos e composições para modular actividades da cinase do mutante de egfr

Country Status (30)

Country	Link
US (2)	US9593098B2 (pt)
EP (4)	EP3207035B1 (pt)
JP (3)	JP6524221B2 (pt)
KR (5)	KR20240074820A (pt)
CN (2)	CN111686110B (pt)
AU (1)	AU2015331166B2 (pt)
BR (1)	BR112017007769B1 (pt)
CA (1)	CA2962914C (pt)
CY (2)	CY1122737T1 (pt)
DK (4)	DK3929190T3 (pt)
ES (3)	ES3009926T3 (pt)
FI (3)	FI4421069T3 (pt)
FR (1)	FR25C1021I2 (pt)
HR (3)	HRP20250213T1 (pt)
HU (4)	HUE048006T2 (pt)
LT (5)	LT3929190T (pt)
MX (3)	MX2017003181A (pt)
NL (1)	NL301329I2 (pt)
NO (1)	NO2025025I1 (pt)
NZ (1)	NZ730012A (pt)
PH (1)	PH12017500488A1 (pt)
PL (3)	PL3604294T3 (pt)
PT (4)	PT3929190T (pt)
RS (3)	RS66529B1 (pt)
RU (1)	RU2727700C2 (pt)
SG (1)	SG11201701960XA (pt)
SI (3)	SI3604294T1 (pt)
SM (3)	SMT202000059T1 (pt)
TW (2)	TWI730331B (pt)
WO (1)	WO2016060443A2 (pt)

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PT3929190T (pt) *	2014-10-13	2025-02-19	Yuhan Corp	Compostos e composições para modular atividades da cinase do mutante de egfr
US9938257B2 (en)	2015-09-11	2018-04-10	Calitor Sciences, Llc	Substituted heteroaryl compounds and methods of use
JP2019501222A (ja)	2016-01-07	2019-01-17	シーエスファーマテックリミテッド	Ｅｇｆｒチロシンキナーゼの臨床的に重要な変異体の選択的阻害薬
JP7030066B2 (ja) *	2016-05-26	2022-03-04	リキュリウムアイピーホールディングスリミテッドライアビリティーカンパニー	Ｅｇｆｒ阻害剤化合物
KR102030886B1 (ko) *	2016-09-23	2019-10-10	재단법인 대구경북첨단의료산업진흥재단	신규한 이미다졸일 피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물
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Publication number	Publication date
HUE054848T2 (hu)	2021-09-28
SMT202100266T1 (it)	2021-07-12
DK3929190T3 (da)	2025-02-24
KR20210011068A (ko)	2021-01-29
JP2019163277A (ja)	2019-09-26
WO2016060443A2 (en)	2016-04-21
AU2015331166A1 (en)	2017-03-30
US20160102076A1 (en)	2016-04-14
HUE048006T2 (hu)	2020-05-28
RS59900B1 (sr)	2020-03-31
PL3207035T3 (pl)	2020-06-01
NZ730012A (en)	2019-06-28
FR25C1021I1 (fr)	2025-08-01
BR112017007769B1 (pt)	2023-10-10
HRP20200201T1 (hr)	2020-05-15
MX2020002168A (es)	2021-09-07
MX2021010761A (es)	2022-06-09
JP6754864B2 (ja)	2020-09-16
MX385942B (es)	2025-03-18
ES2770058T3 (es)	2020-06-30
CA2962914A1 (en)	2016-04-21
PT3929190T (pt)	2025-02-19
EP3604294A1 (en)	2020-02-05
FR25C1021I2 (fr)	2026-02-06
SMT202500069T1 (it)	2025-03-12
AU2015331166B2 (en)	2018-04-26
KR102662358B1 (ko)	2024-04-30
KR102487451B1 (ko)	2023-01-11
FIC20250023I1 (fi)	2025-06-06
FI4421069T3 (fi)	2026-01-21
RU2017116598A (ru)	2018-11-21
ES2879474T3 (es)	2021-11-22
RS66529B1 (sr)	2025-03-31
RS61865B1 (sr)	2021-06-30
CY1124359T1 (el)	2022-07-22
LT3929190T (lt)	2025-02-25
TWI730331B (zh)	2021-06-11
PT3604294T (pt)	2021-07-29
EP3604294B1 (en)	2021-05-05
CN111686110A (zh)	2020-09-22
PL3929190T3 (pl)	2025-06-09
TWI664173B (zh)	2019-07-01
EP3929190A1 (en)	2021-12-29
CN106795144B (zh)	2020-06-16
LTPA2025522I1 (pt)	2025-06-25
BR112017007769A2 (pt)	2018-01-16
DK4421069T3 (da)	2026-01-19
SI3929190T1 (sl)	2025-04-30
KR20230010836A (ko)	2023-01-19
CY1122737T1 (el)	2021-03-12
SG11201701960XA (en)	2017-04-27
HRP20210949T1 (hr)	2021-09-03
WO2016060443A3 (en)	2016-06-23
SI3207035T1 (sl)	2020-04-30
CN111686110B (zh)	2023-06-16
EP3207035A2 (en)	2017-08-23
HUS2500023I1 (hu)	2025-06-28
JP2017530999A (ja)	2017-10-19
KR20170066650A (ko)	2017-06-14
HUE070874T2 (hu)	2025-07-28
SI3604294T1 (sl)	2021-08-31
ES3009926T3 (en)	2025-03-31
EP4421069A1 (en)	2024-08-28
NO2025025I1 (no)	2025-06-05
DK3604294T3 (da)	2021-06-28
CN106795144A (zh)	2017-05-31
RU2020123547A (ru)	2020-08-18
EP4421069B1 (en)	2025-12-10
JP2020196740A (ja)	2020-12-10
KR102073854B1 (ko)	2020-02-05
FI3929190T3 (fi)	2025-02-28
KR102208775B1 (ko)	2021-01-28
SMT202000059T1 (it)	2020-03-13
JP6524221B2 (ja)	2019-06-05
CA2962914C (en)	2018-10-23
EP3207035B1 (en)	2019-11-20
TW201938553A (zh)	2019-10-01
EP3207035A4 (en)	2018-03-14
HRP20250213T1 (hr)	2025-04-25
EP3929190B1 (en)	2024-12-25
USRE50528E1 (en)	2025-08-12
MX2017003181A (es)	2017-07-20
KR20200014944A (ko)	2020-02-11
LT3604294T (lt)	2021-07-26
RU2017116598A3 (pt)	2018-11-21
DK3207035T3 (da)	2020-01-27
TW201619150A (zh)	2016-06-01
LT3207035T (lt)	2020-02-25
RU2727700C2 (ru)	2020-07-23
PL3604294T3 (pl)	2021-11-02
PH12017500488A1 (en)	2017-07-31
LT4421069T (lt)	2026-02-10
KR20240074820A (ko)	2024-05-28
US9593098B2 (en)	2017-03-14
NL301329I2 (nl)	2025-09-09
PT3207035T (pt)	2020-02-19

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