[go: up one dir, main page]

PT3018145T - Meios e métodos para tratar o dlbcl - Google Patents

Meios e métodos para tratar o dlbcl

Info

Publication number
PT3018145T
PT3018145T PT151950763T PT15195076T PT3018145T PT 3018145 T PT3018145 T PT 3018145T PT 151950763 T PT151950763 T PT 151950763T PT 15195076 T PT15195076 T PT 15195076T PT 3018145 T PT3018145 T PT 3018145T
Authority
PT
Portugal
Prior art keywords
methods
treating dlbcl
dlbcl
treating
Prior art date
Application number
PT151950763T
Other languages
English (en)
Inventor
Zugmaier Gerhard
Nagorsen Dirk
Scheele Juergen
Original Assignee
Amgen Res Munich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45023802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3018145(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Res Munich Gmbh filed Critical Amgen Res Munich Gmbh
Publication of PT3018145T publication Critical patent/PT3018145T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
PT151950763T 2010-10-27 2011-10-27 Meios e métodos para tratar o dlbcl PT3018145T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40710710P 2010-10-27 2010-10-27

Publications (1)

Publication Number Publication Date
PT3018145T true PT3018145T (pt) 2018-05-17

Family

ID=45023802

Family Applications (3)

Application Number Title Priority Date Filing Date
PT181641754T PT3412687T (pt) 2010-10-27 2011-10-27 Métodos de tratamento de dlbcl
PT117876334T PT2632954E (pt) 2010-10-27 2011-10-27 Meios e métodos para tratar dlbcl
PT151950763T PT3018145T (pt) 2010-10-27 2011-10-27 Meios e métodos para tratar o dlbcl

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PT181641754T PT3412687T (pt) 2010-10-27 2011-10-27 Métodos de tratamento de dlbcl
PT117876334T PT2632954E (pt) 2010-10-27 2011-10-27 Meios e métodos para tratar dlbcl

Country Status (31)

Country Link
US (2) US9192665B2 (pt)
EP (3) EP3018145B1 (pt)
JP (3) JP5997168B2 (pt)
KR (1) KR101889995B1 (pt)
CN (2) CN103459425B (pt)
AU (1) AU2011322581B2 (pt)
CA (1) CA2815119C (pt)
CL (1) CL2013001138A1 (pt)
CR (1) CR20130245A (pt)
CY (3) CY1117155T1 (pt)
DK (3) DK3018145T3 (pt)
EA (1) EA032139B1 (pt)
ES (3) ES2787044T3 (pt)
HR (2) HRP20151444T4 (pt)
HU (3) HUE027678T2 (pt)
IL (3) IL225924A (pt)
LT (2) LT3412687T (pt)
MA (1) MA34619B1 (pt)
ME (1) ME02311B (pt)
MY (1) MY163057A (pt)
NZ (2) NZ701715A (pt)
PH (1) PH12013500826A1 (pt)
PL (3) PL2632954T5 (pt)
PT (3) PT3412687T (pt)
RS (3) RS57260B1 (pt)
SG (1) SG189869A1 (pt)
SI (3) SI3018145T1 (pt)
SM (3) SMT201800319T1 (pt)
TR (1) TR201808019T4 (pt)
UA (1) UA111175C2 (pt)
WO (1) WO2012055961A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2417065T3 (es) 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
ES2787044T3 (es) * 2010-10-27 2020-10-14 Amgen Res Munich Gmbh Métodos para tratar LDCBG
PL2637670T5 (pl) * 2010-11-10 2024-06-10 Amgen Research (Munich) Gmbh Zapobieganie działaniom niepożądanym spowodowanym przez domeny wiążące specyficzne względem CD3
JO3529B1 (ar) * 2013-02-08 2020-07-05 Amgen Res Munich Gmbh مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
JP6734774B2 (ja) 2013-10-15 2020-08-05 ザ スクリプス リサーチ インスティテュート ペプチドキメラ抗原受容体t細胞スイッチおよびその使用
WO2016154621A1 (en) 2015-03-26 2016-09-29 The California Institute For Biomedical Research SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
WO2016168773A2 (en) 2015-04-15 2016-10-20 The California Institute For Biomedical Research Optimized pne-based chimeric receptor t cell switches and uses thereof
EA202090931A3 (ru) 2015-05-18 2020-10-30 Тср2 Терапьютикс Инк. Композиции и способы перепрограммирования tcr с помощью гибридных белков
CA3001910A1 (en) * 2015-10-13 2017-04-20 Eureka Therapeutics, Inc. Antibody agents specific for human cd19 and uses thereof
JP2019532017A (ja) * 2016-07-14 2019-11-07 フレッド ハッチンソン キャンサー リサーチ センター がんを治療するための異なるエピトープ結合を示す複数の二重特異性結合ドメイン構築物
JP7109789B2 (ja) 2016-08-02 2022-08-01 ティーシーアール2 セラピューティクス インク. 融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
CN112280796A (zh) 2016-10-07 2021-01-29 T细胞受体治疗公司 使用融合蛋白进行t细胞受体重编程的组合物和方法
CA3040343A1 (en) 2016-10-19 2018-04-26 California Institute For Biomedical Research Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
CA3044593A1 (en) 2016-11-22 2018-05-31 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
JP2021508477A (ja) 2017-12-29 2021-03-11 オンコラス, インコーポレイテッド 治療用ポリペプチドの腫瘍溶解性ウイルス送達
WO2020099513A1 (en) * 2018-11-13 2020-05-22 Lipoxen Technologies Limited Glycopolysialylation of blinatumomab
CN118593691A (zh) * 2019-05-03 2024-09-06 凯德药业股份有限公司 施用嵌合抗原受体免疫疗法的方法
KR20230031981A (ko) 2019-05-14 2023-03-07 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
CN113874398B (zh) 2019-05-21 2025-08-01 诺华股份有限公司 Cd19结合分子及其用途
US12006366B2 (en) 2020-06-11 2024-06-11 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
IL303384A (en) * 2020-12-04 2023-08-01 Morphosys Ag Anti-CD19 combination therapy
FI4284512T3 (fi) 2021-01-28 2025-05-22 Regeneron Pharma Koostumuksia ja menetelmiä sytokiinien vapautumisoireyhtymän hoitamiseksi
CA3247475A1 (en) 2022-04-11 2023-10-19 Regeneron Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR THE DESTRUCTION OF UNIVERSAL TUMOR CELLS
AU2024223918A1 (en) 2023-02-17 2025-09-11 Regeneron Pharmaceuticals, Inc. Induced nk cells responsive to cd3/taa bispecific antibodies

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856559T2 (de) 1987-05-21 2004-04-29 Micromet Ag Multifunktionelle Proteine mit vorbestimmter Zielsetzung
DE69909459T2 (de) 1998-04-21 2004-05-27 Micromet Ag Cd19xcd3 spezifische polypeptide und deren verwendung
WO2004106381A1 (en) 2003-05-31 2004-12-09 Micromet Ag Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
ES2341252T3 (es) 2003-11-28 2010-06-17 Micromet Ag Composiciones que comprenden polipeptidos.
KR101335798B1 (ko) 2005-02-15 2013-12-02 듀크 유니버시티 항-cd19 항체 및 종양학에서 이의 용도
ES2417065T3 (es) * 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
AU2006326727A1 (en) 2005-12-16 2007-06-21 Amgen Research (Munich) Gmbh Means and methods for the treatment of tumorous diseases
CN101331151A (zh) * 2005-12-16 2008-12-24 麦克罗梅特股份公司 治疗肿瘤性疾病的方式和方法
CA2662340C (en) 2006-09-08 2016-08-02 Medimmune, Llc Humanized anti-cd19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
PT2520590T (pt) 2007-04-03 2018-11-14 Amgen Res Munich Gmbh Domínio de ligação específico de espécies cruzadas
ES2727585T3 (es) * 2008-11-07 2019-10-17 Amgen Res Munich Gmbh Tratamiento de leucemia linfoblástica aguda
HUE025759T2 (en) * 2009-10-27 2016-04-28 Amgen Res Munich Gmbh Dosage regimen for administering a cd19xcd3 bispecific antibody
ES2787044T3 (es) * 2010-10-27 2020-10-14 Amgen Res Munich Gmbh Métodos para tratar LDCBG

Also Published As

Publication number Publication date
NZ609201A (en) 2015-01-30
RS54525B2 (sr) 2021-08-31
RS60094B1 (sr) 2020-05-29
IL260774B (en) 2019-02-28
CA2815119C (en) 2023-01-10
EP3018145B1 (en) 2018-04-04
PL2632954T5 (pl) 2021-11-02
SMT201600050B (it) 2016-04-29
ES2787044T3 (es) 2020-10-14
SMT202000232T1 (it) 2020-07-08
HK1188229A1 (en) 2014-04-25
EA032139B1 (ru) 2019-04-30
US10696744B2 (en) 2020-06-30
JP2016164192A (ja) 2016-09-08
DK2632954T4 (da) 2021-08-09
SI2632954T1 (sl) 2016-02-29
CN103459425A (zh) 2013-12-18
HRP20151444T4 (hr) 2021-08-20
PT3412687T (pt) 2020-04-03
JP6522722B2 (ja) 2019-05-29
ES2563439T5 (es) 2022-02-04
EP3412687B1 (en) 2020-03-18
ME02311B (me) 2016-06-20
DK3018145T3 (en) 2018-05-28
ES2563439T3 (es) 2016-03-15
HUE027678T2 (en) 2016-11-28
JP2013540799A (ja) 2013-11-07
AU2011322581B2 (en) 2015-04-23
JP2018039838A (ja) 2018-03-15
SG189869A1 (en) 2013-06-28
SI3412687T1 (sl) 2020-07-31
ES2675299T3 (es) 2018-07-10
PL3018145T3 (pl) 2018-09-28
IL225924A0 (en) 2013-06-27
IL256110A (en) 2018-02-28
HRP20180882T1 (hr) 2018-07-27
CN103459425B (zh) 2015-11-25
US20130287778A1 (en) 2013-10-31
DK3412687T3 (da) 2020-05-11
NZ701715A (en) 2016-05-27
IL225924A (en) 2017-12-31
CA2815119A1 (en) 2012-05-03
SMT201800319T1 (it) 2018-07-17
CN105251003A (zh) 2016-01-20
AU2011322581A1 (en) 2013-05-09
CL2013001138A1 (es) 2014-11-14
RS54525B1 (sr) 2016-06-30
HRP20151444T1 (hr) 2016-01-29
SI2632954T2 (sl) 2021-11-30
KR20140019298A (ko) 2014-02-14
NZ719768A (en) 2021-07-30
PT2632954E (pt) 2016-02-03
EP2632954A1 (en) 2013-09-04
EP3018145A1 (en) 2016-05-11
LT3018145T (lt) 2018-05-10
JP6254220B2 (ja) 2017-12-27
WO2012055961A1 (en) 2012-05-03
DK2632954T3 (en) 2016-02-01
SI3018145T1 (en) 2018-08-31
EP3412687A1 (en) 2018-12-12
UA111175C2 (uk) 2016-04-11
MY163057A (en) 2017-08-15
EA201390387A1 (ru) 2013-10-30
IL256110B (en) 2018-08-30
PL2632954T3 (pl) 2016-05-31
KR101889995B1 (ko) 2018-08-20
CR20130245A (es) 2013-09-20
JP5997168B2 (ja) 2016-09-28
EP2632954B1 (en) 2015-11-25
LT3412687T (lt) 2020-07-27
US20160208001A1 (en) 2016-07-21
US9192665B2 (en) 2015-11-24
CY1117155T1 (el) 2017-04-05
MA34619B1 (fr) 2013-10-02
CY1120227T1 (el) 2018-12-12
PH12013500826A1 (en) 2013-06-17
CN105251003B (zh) 2019-08-02
EP2632954B2 (en) 2021-07-07
HUE048639T2 (hu) 2020-08-28
HUE037786T2 (hu) 2018-09-28
TR201808019T4 (tr) 2018-06-21
RS57260B1 (sr) 2018-08-31
PL3412687T3 (pl) 2020-07-27
CY1123251T1 (el) 2021-10-29

Similar Documents

Publication Publication Date Title
HRP20180882T1 (hr) Sredstva za i postupci liječenja dlbcl
AP3269A (en) Methods and compounds for treating paramyxoviridaevirus infections
PL2649391T3 (pl) Urządzenie do suszenia i sposoby suszenia
ZA201303423B (en) Compositions and methods for treating myelofibrosis
GB201003190D0 (en) Apparatus and method
PL2525953T3 (pl) Sposób i urządzenie do obróbki i odkażania
ZA201304360B (en) Method and device for treating biomass
EP2712445A4 (en) METHOD AND APPARATUS FOR ZONE REDUCTION AND / OR MEMORY POWER SUPPLY
GB201002083D0 (en) Apparatus for improving and/or maintaining numerical ability
GB2483684B (en) Range determination apparatus and method
GB201005885D0 (en) Apparatus and method
PT2627818T (pt) Método e disposição para tratamento de pasta
GB201003255D0 (en) Apparatus and method
GB201105826D0 (en) Apparatus and method
GB201021057D0 (en) Method and apparatus
GB201006393D0 (en) An apparatus and associated methods
GB201011768D0 (en) Apparatus and methods for operation
GB201000806D0 (en) Apparatus and methods
GB201010290D0 (en) Apparatus and methods
GB201008082D0 (en) Apparatus and method
GB201003264D0 (en) Apparatus and method
GB201001033D0 (en) Method and apparatus
GB201016993D0 (en) Apparatus and method
GB201010267D0 (en) Apparatus and method
GB201001459D0 (en) Apparatus and method