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PT2865663T - Derivado de indanossulfamida inovador - Google Patents

Derivado de indanossulfamida inovador

Info

Publication number
PT2865663T
PT2865663T PT138077078T PT13807707T PT2865663T PT 2865663 T PT2865663 T PT 2865663T PT 138077078 T PT138077078 T PT 138077078T PT 13807707 T PT13807707 T PT 13807707T PT 2865663 T PT2865663 T PT 2865663T
Authority
PT
Portugal
Prior art keywords
novel
derivative
indanesulfamide derivative
novel indanesulfamide
indanesulfamide
Prior art date
Application number
PT138077078T
Other languages
English (en)
Inventor
Kazuta Yuji
Watanabe Toru
Sorimachi Keiichi
Saito Minako
Kita Yoichi
Tanaka Toshiaki
Higashiyama Hiroyuki
Hanada Takahisa
Teramoto Tetsuyuki
Kosasa Takashi
Ishikawa Yukio
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of PT2865663T publication Critical patent/PT2865663T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/08Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT138077078T 2012-06-21 2013-06-17 Derivado de indanossulfamida inovador PT2865663T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261662626P 2012-06-21 2012-06-21
US201261709737P 2012-10-04 2012-10-04
US201361751331P 2013-01-11 2013-01-11

Publications (1)

Publication Number Publication Date
PT2865663T true PT2865663T (pt) 2017-06-02

Family

ID=49768740

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138077078T PT2865663T (pt) 2012-06-21 2013-06-17 Derivado de indanossulfamida inovador

Country Status (34)

Country Link
US (1) US9018260B2 (pt)
EP (1) EP2865663B1 (pt)
JP (1) JP5883135B2 (pt)
KR (1) KR101951519B1 (pt)
CN (1) CN104395285B (pt)
AR (1) AR091506A1 (pt)
AU (1) AU2013278450B2 (pt)
BR (1) BR112014031565B1 (pt)
CA (1) CA2877097C (pt)
CL (1) CL2014003429A1 (pt)
CY (1) CY1119171T1 (pt)
DK (1) DK2865663T3 (pt)
ES (1) ES2628374T3 (pt)
HR (1) HRP20170863T1 (pt)
HU (1) HUE033583T2 (pt)
IL (1) IL236295A (pt)
JO (1) JO3263B1 (pt)
LT (1) LT2865663T (pt)
ME (1) ME02753B (pt)
MX (1) MX355261B (pt)
MY (1) MY169073A (pt)
NZ (1) NZ702974A (pt)
PE (1) PE20150284A1 (pt)
PH (1) PH12014502805B1 (pt)
PL (1) PL2865663T3 (pt)
PT (1) PT2865663T (pt)
RS (1) RS56073B1 (pt)
RU (1) RU2619937C2 (pt)
SG (1) SG11201408359PA (pt)
SI (1) SI2865663T1 (pt)
SM (1) SMT201700287T1 (pt)
TW (1) TWI597263B (pt)
WO (1) WO2013191144A1 (pt)
ZA (1) ZA201409248B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3417851T3 (pl) 2013-09-09 2020-12-14 Peloton Therapeutics, Inc. Etery arylowe i ich zastosowanie
US9884843B2 (en) 2013-12-16 2018-02-06 Peloton Therapeutics, Inc. Cyclic sulfone and sulfoximine analogs and uses thereof
CN105792821B (zh) * 2013-12-19 2018-05-04 卫材R&D管理有限公司 包含1-茚满硫酰胺衍生物的疼痛治疗剂和/或预防剂
WO2016145045A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Compositions for use in treating glioblastoma
US10807948B2 (en) 2015-03-11 2020-10-20 Peloton Therapeutics, Inc. Aromatic compounds and uses thereof
US10278942B2 (en) 2015-03-11 2019-05-07 Peloton Therapeutics, Inc. Compositions for use in treating pulmonary arterial hypertension
WO2016144826A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Substituted pyridines and uses thereof
WO2016168510A1 (en) 2015-04-17 2016-10-20 Peloton Therapeutics, Inc. Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof
US9796697B2 (en) 2015-06-12 2017-10-24 Peloton Therapeutics, Inc. Tricyclic inhibitors of HIF-2-alpha and uses thereof
JP7265526B2 (ja) 2018-03-20 2023-04-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 てんかん治療剤
JP2024026905A (ja) * 2020-11-25 2024-02-29 エーザイ・アール・アンド・ディー・マネジメント株式会社 てんかん治療剤
CN118946348A (zh) 2022-04-27 2024-11-12 卫材R&D管理有限公司 用于治疗帕金森病的药物组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3383414A (en) 1964-08-26 1968-05-14 Sandoz Ag Benzocycloalkyl sulfamides
US3709677A (en) 1969-06-25 1973-01-09 Sandoz Ag N-substituted sulfamoyl compounds useful as herbicides
EP1401805A1 (en) * 2001-06-26 2004-03-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Valproyltaurinamide derivatives as anticonvulsant and cns active agents
TW200307539A (en) * 2002-02-01 2003-12-16 Bristol Myers Squibb Co Cycloalkyl inhibitors of potassium channel function
CA2578407A1 (en) * 2004-08-24 2006-03-02 Janssen Pharmaceutica N.V. Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents
US20070155823A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents
CN100572365C (zh) * 2006-01-26 2009-12-23 全哲山 用作抗癫痫药的1,2,4-三唑并[4,3-a]喹啉-1-酮衍生物及其可药用盐
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物
CL2007002994A1 (es) 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明(cyclopamine)類似物類
AR070949A1 (es) * 2007-10-19 2010-05-19 Solvay Pharm Gmbh Compuestos derivados de sulfamato de uso medico, medicamentos y composiciones farmaceuticas que los comprenden, procedimientos para preparar estos compuestos y su uso
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
WO2010115952A1 (en) 2009-04-09 2010-10-14 N.V. Organon Indane derivatives
ES2675799T3 (es) * 2009-11-13 2018-07-12 Celgene International Ii Sàrl Moduladores selectivos del receptor esfingosina 1-fosfato heterocíclica
JP5650233B2 (ja) * 2009-11-13 2015-01-07 レセプトス インコーポレイテッドReceptos, Inc. 選択的スフィンゴシン−1−リン酸受容体変調因子および不斉合成方法
WO2011097337A1 (en) * 2010-02-04 2011-08-11 Advanced Neural Dynamics, Inc. Novel sulfamides exhibiting neuroprotective action and methods for use thereof
US20120077814A1 (en) * 2010-09-10 2012-03-29 Zhong Wang Sulfonamide, sulfamate, and sulfamothioate derivatives

Also Published As

Publication number Publication date
ZA201409248B (en) 2015-12-23
SMT201700287T1 (it) 2017-07-18
BR112014031565A8 (pt) 2021-06-08
HK1207363A1 (en) 2016-01-29
CA2877097A1 (en) 2013-12-27
JO3263B1 (ar) 2018-09-16
ME02753B (me) 2018-01-20
TW201402530A (zh) 2014-01-16
WO2013191144A1 (ja) 2013-12-27
PL2865663T3 (pl) 2017-09-29
IL236295A0 (en) 2015-02-26
HUE033583T2 (hu) 2017-12-28
US20140371319A1 (en) 2014-12-18
EP2865663B1 (en) 2017-04-05
CA2877097C (en) 2018-08-07
JP5883135B2 (ja) 2016-03-09
MY169073A (en) 2019-02-13
AU2013278450B2 (en) 2017-04-20
CL2014003429A1 (es) 2015-03-27
US9018260B2 (en) 2015-04-28
MX2014015492A (es) 2015-05-08
PH12014502805A1 (en) 2015-02-23
JPWO2013191144A1 (ja) 2016-05-26
EP2865663A4 (en) 2016-02-17
DK2865663T3 (en) 2017-06-19
RU2014151013A (ru) 2016-08-10
RS56073B1 (sr) 2017-10-31
PH12014502805B1 (en) 2015-02-23
CY1119171T1 (el) 2018-02-14
RU2619937C2 (ru) 2017-05-22
PE20150284A1 (es) 2015-02-21
SI2865663T1 (sl) 2017-07-31
KR101951519B1 (ko) 2019-02-22
AR091506A1 (es) 2015-02-11
IL236295A (en) 2016-09-29
KR20150032838A (ko) 2015-03-30
AU2013278450A1 (en) 2015-01-22
TWI597263B (zh) 2017-09-01
HRP20170863T1 (hr) 2017-09-08
CN104395285B (zh) 2016-04-13
LT2865663T (lt) 2017-07-10
BR112014031565B1 (pt) 2022-04-12
CN104395285A (zh) 2015-03-04
EP2865663A1 (en) 2015-04-29
ES2628374T3 (es) 2017-08-02
SG11201408359PA (en) 2015-01-29
NZ702974A (en) 2016-03-31
MX355261B (es) 2018-04-12
BR112014031565A2 (pt) 2017-06-27

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