PT1390070T - Utilização de inibidores de il-18 para o tratamento ou prevenção de lesões do snc - Google Patents

Utilização de inibidores de il-18 para o tratamento ou prevenção de lesões do snc

Info

Publication number: PT1390070T
Authority: PT; Portugal
Prior art keywords: inhibitors; treating; cns injuries; preventing cns; preventing
Prior art date: 2001-05-25

Application number

PT2740641T

Other languages

English (en)

Inventor

Shohami Esther

Original Assignee

Ares Trading Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2002-05-23

Publication date

2017-03-01

2002-05-23 Application filed by Ares Trading Sa filed Critical Ares Trading Sa

2017-03-01 Publication of PT1390070T publication Critical patent/PT1390070T/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Neurology (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

PT2740641T 2001-05-25 2002-05-23 Utilização de inibidores de il-18 para o tratamento ou prevenção de lesões do snc PT1390070T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01112067		2001-05-25

Publications (1)

Publication Number	Publication Date
PT1390070T true PT1390070T (pt)	2017-03-01

Family

ID=8177454

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT2740641T PT1390070T (pt)	2001-05-25	2002-05-23	Utilização de inibidores de il-18 para o tratamento ou prevenção de lesões do snc

Country Status (29)

Country	Link
US (1)	US7655616B2 (pt)
EP (1)	EP1390070B1 (pt)
JP (1)	JP4344142B2 (pt)
KR (1)	KR20040030625A (pt)
CN (1)	CN1305529C (pt)
AU (1)	AU2002314103B2 (pt)
BG (1)	BG66395B1 (pt)
BR (1)	BR0210007A (pt)
CA (1)	CA2445664C (pt)
CY (1)	CY1119190T1 (pt)
CZ (1)	CZ307321B6 (pt)
DK (1)	DK1390070T3 (pt)
EA (1)	EA006744B1 (pt)
EE (1)	EE05263B1 (pt)
ES (1)	ES2617084T3 (pt)
HR (1)	HRP20030842B1 (pt)
HU (1)	HU230294B1 (pt)
IL (2)	IL159014A0 (pt)
LT (1)	LT1390070T (pt)
ME (1)	ME00550B (pt)
MX (1)	MXPA03010743A (pt)
NO (1)	NO331882B1 (pt)
PL (1)	PL216228B1 (pt)
PT (1)	PT1390070T (pt)
RS (1)	RS56006B1 (pt)
SK (1)	SK288413B6 (pt)
UA (1)	UA80396C2 (pt)
WO (1)	WO2002096456A1 (pt)
ZA (1)	ZA200308172B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080076708A1 (en)	2003-05-13	2008-03-27	Valter Altarocca	Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
EP1780542A4 (en) *	2004-06-30	2008-05-14	Atsuo Sekiyama	AGENT INDICATING A NON-INFLAMMATORY RESPONSE TO A STRESS AND USE THEREOF
SI1888100T1 (sl) *	2005-06-03	2012-01-31	Merck Serono Sa	Uporaba izooblik il-18pb za zdravljenje in/ali prepreäśevanje nevroloĺ kih vnetnih bolezni
PL1885753T3 (pl)	2005-06-03	2011-12-30	Ares Trading Sa	Wytwarzanie rekombinowanego białka wiążącego IL-18
ATE529433T1 (de)	2005-06-10	2011-11-15	Ares Trading Sa	Verfahren zur reinigung eines il-18-bindenden proteins
US8685400B2 (en) *	2007-07-30	2014-04-01	University Of Miami	Modulating inflammasome activity and inflammation in the central nervous system
KR102321172B1 (ko) *	2013-09-05	2021-11-05	에이비2 바이오 에스에이	염증성 질환에서 il-18 결합 단백질(ｉｌ-18ｂｐ)
CA2972689A1 (en) *	2015-03-05	2016-09-09	Ab2 Bio Sa	Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0873453A (ja) *	1994-09-02	1996-03-19	Otsuka Pharmaceut Co Ltd	サイトカイン阻害剤
IL121860A0 (en) *	1997-08-14	1998-02-22	Yeda Res & Dev	Interleukin-18 binding proteins their preparation and use
ES2244178T3 (es) *	1998-03-09	2005-12-01	Vertex Pharmaceuticals Incorporated	Derivados de 1,2-diazepan como inhibidores de la enzima convertidora de interleuquina-1 beta.
CA2276216A1 (en) *	1998-06-24	1999-12-24	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	An artificial peptide capable of neutralizing the biological activity of interleukin-18
EA007014B1 (ru) *	2000-05-05	2006-06-30	Апплайд Резеч Системз Арс Холдинг Н.В.	Применение il-18 в качестве диагностического маркера
AU2001266289A1 (en) *	2000-06-23	2002-01-02	Yissum Research Development Company Of The Hebrew University Of Jerusalem	2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury
AU2002224417A1 (en) *	2000-10-18	2002-04-29	Immunex Corporation	Methods for treating il-18 mediated disorders
US6671553B1 (en) *	2001-05-23	2003-12-30	Pacesetter, Inc.	Implantable cardiac lead having terminating connector strain relief and method of manufacture

2002
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en not_active Ceased
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko not_active Ceased
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/en not_active Expired - Lifetime
2003
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown

Also Published As

Publication number	Publication date
EP1390070B1 (en)	2017-02-08
YU89403A (sh)	2006-05-25
KR20040030625A (ko)	2004-04-09
UA80396C2 (en)	2007-09-25
CY1119190T1 (el)	2018-02-14
IL159014A (en)	2012-05-31
NO331882B1 (no)	2012-04-23
ZA200308172B (en)	2004-10-21
SK288413B6 (sk)	2016-10-03
MXPA03010743A (es)	2004-03-02
HRP20030842A2 (en)	2005-08-31
EP1390070A1 (en)	2004-02-25
RS56006B1 (sr)	2017-09-29
CA2445664C (en)	2012-03-06
SK16032003A3 (sk)	2004-05-04
NO20035160D0 (no)	2003-11-20
HUP0304067A3 (en)	2006-01-30
US7655616B2 (en)	2010-02-02
EA200301299A1 (ru)	2004-04-29
LT1390070T (lt)	2017-03-10
IL159014A0 (en)	2004-05-12
NO20035160L (no)	2003-11-20
HU230294B1 (hu)	2015-12-28
CN1305529C (zh)	2007-03-21
EE200300582A (et)	2004-02-16
ME00550B (me)	2011-10-10
CZ307321B6 (cs)	2018-06-06
BG108451A (en)	2005-02-28
CA2445664A1 (en)	2002-12-05
HUP0304067A2 (hu)	2004-03-29
HRP20030842B1 (hr)	2017-06-02
AU2002314103B8 (en)	2002-12-09
AU2002314103B2 (en)	2007-07-12
ES2617084T3 (es)	2017-06-15
JP4344142B2 (ja)	2009-10-14
EA006744B1 (ru)	2006-04-28
DK1390070T3 (en)	2017-04-24
PL216228B1 (pl)	2014-03-31
BG66395B1 (bg)	2013-12-31
CZ20033268A3 (en)	2004-07-14
WO2002096456A1 (en)	2002-12-05
BR0210007A (pt)	2004-08-10
CN1535160A (zh)	2004-10-06
US20040191247A1 (en)	2004-09-30
PL367545A1 (en)	2005-02-21
EE05263B1 (et)	2010-02-15
HK1069762A1 (en)	2005-06-03
JP2004534777A (ja)	2004-11-18

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