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PL2970283T3 - Podstawione (benzylocyjanometylo)amidy kwasu 2-aza-bicyklo[2.2.1]heptano-3-karboksylowego będące inhibitorami katepsyny c - Google Patents

Podstawione (benzylocyjanometylo)amidy kwasu 2-aza-bicyklo[2.2.1]heptano-3-karboksylowego będące inhibitorami katepsyny c

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Publication number
PL2970283T3
PL2970283T3 PL14709652T PL14709652T PL2970283T3 PL 2970283 T3 PL2970283 T3 PL 2970283T3 PL 14709652 T PL14709652 T PL 14709652T PL 14709652 T PL14709652 T PL 14709652T PL 2970283 T3 PL2970283 T3 PL 2970283T3
Authority
PL
Poland
Prior art keywords
cathepsin
aza
bicyclo
heptane
cyano
Prior art date
Application number
PL14709652T
Other languages
English (en)
Inventor
Ralf Anderskewitz
Matthias Grauert
Marc Grundl
Peter Wilhelm Haebel
Thorsten Oost
Alexander Pautsch
Stefan Peters
Florian Binder
Viktor VINTONYAK
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of PL2970283T3 publication Critical patent/PL2970283T3/pl

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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