[go: up one dir, main page]

PL1991680T3 - Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza - Google Patents

Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza

Info

Publication number
PL1991680T3
PL1991680T3 PL07752601T PL07752601T PL1991680T3 PL 1991680 T3 PL1991680 T3 PL 1991680T3 PL 07752601 T PL07752601 T PL 07752601T PL 07752601 T PL07752601 T PL 07752601T PL 1991680 T3 PL1991680 T3 PL 1991680T3
Authority
PL
Poland
Prior art keywords
expression
host cells
translation components
orthogonal translation
eubacterial host
Prior art date
Application number
PL07752601T
Other languages
English (en)
Inventor
Youngha Ryu
Peter G Schultz
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of PL1991680T3 publication Critical patent/PL1991680T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07752601T 2006-03-09 2007-03-07 Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza PL1991680T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US78097306P 2006-03-09 2006-03-09
US78349706P 2006-03-17 2006-03-17
US85533606P 2006-10-29 2006-10-29
EP07752601.0A EP1991680B1 (en) 2006-03-09 2007-03-07 System for the expression of orthogonal translation components in eubacterial host cells
PCT/US2007/005914 WO2007103490A2 (en) 2006-03-09 2007-03-07 System for the expression of orthogonal translation components in eubacterial host cells

Publications (1)

Publication Number Publication Date
PL1991680T3 true PL1991680T3 (pl) 2014-01-31

Family

ID=38475556

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07752601T PL1991680T3 (pl) 2006-03-09 2007-03-07 Układ do ekspresji ortogonalnych składników translacji w eubakteryjnych komórkach gospodarza

Country Status (14)

Country Link
US (3) US7960141B2 (pl)
EP (1) EP1991680B1 (pl)
JP (1) JP5589186B2 (pl)
KR (1) KR20080106430A (pl)
CN (1) CN101400796B (pl)
AU (1) AU2007223830A1 (pl)
BR (1) BRPI0709935A2 (pl)
CA (1) CA2638763A1 (pl)
ES (1) ES2432391T3 (pl)
IL (1) IL193394A0 (pl)
MX (1) MX2008011470A (pl)
PL (1) PL1991680T3 (pl)
PT (1) PT1991680E (pl)
WO (1) WO2007103490A2 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002086075A2 (en) * 2001-04-19 2002-10-31 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
WO2004035605A2 (en) * 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
MXPA05011127A (es) 2003-04-17 2006-03-10 Scripps Research Inst Expansion del codigo genetico eucariontico.
PT1666604E (pt) * 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
EP1794312A4 (en) * 2004-09-22 2009-08-12 Scripps Research Inst LOCAL LABELING OF PROTEINS FOR NMR STUDIES
EP2383340B1 (en) 2004-10-27 2014-07-16 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
US7960141B2 (en) * 2006-03-09 2011-06-14 The Scripps Research Institute Systems for the expression of orthogonal translation components in eubacterial host cells
WO2007109035A2 (en) 2006-03-16 2007-09-27 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
BRPI0711811A2 (pt) 2006-05-23 2011-12-06 Scripps Research Inst aminoácidos de cumarina fluorescente geneticamente codificados
CA2663052A1 (en) 2006-09-21 2008-03-27 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
US20080166766A1 (en) 2006-10-18 2008-07-10 The Scripps Research Institute Genetic incorporation of unnatural amino acids into proteins in mammalian cells
WO2009059056A2 (en) * 2007-11-02 2009-05-07 The Scripps Research Institute A genetically encoded boronate amino acid
US8647840B2 (en) * 2007-12-11 2014-02-11 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris
EP2249865A4 (en) * 2008-02-08 2012-04-04 Scripps Research Inst BREAKING IMMUNOLOGICAL TOLERANCE WITH A GENETICALLY ENCODED UNNATURAL AMINO ACID
NO2337846T3 (pl) 2008-09-26 2018-06-16
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
CN102307905B (zh) 2008-12-10 2015-11-25 斯克利普斯研究院 利用化学反应性非天然氨基酸产生载体-肽偶联物
WO2012024452A2 (en) * 2010-08-17 2012-02-23 Ambrx, Inc. Modified relaxin polypeptides and their uses
KR20160027217A (ko) 2012-05-23 2016-03-09 에프. 호프만-라 로슈 아게 내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
UY35368A (es) 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
US10005838B2 (en) 2013-07-19 2018-06-26 The Regents Of The University Of California Milk fat globule epidermal growth factor 8 regulates fatty acid uptake
JP2020500020A (ja) 2016-11-14 2020-01-09 ノバルティス アーゲー 融合誘導性タンパク質ｍｉｎｉｏｎに関連する組成物、方法、および治療上の使用
CN109963579A (zh) 2016-11-14 2019-07-02 诺华股份有限公司 用于治疗软骨损伤和关节炎的方法和组合物
MY193457A (en) 2017-02-08 2022-10-14 Bristol Myers Squibb Co Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
AU2020378327A1 (en) * 2019-11-05 2022-05-26 Nitro Biosciences, Inc. Biosynthesis of para-nitro-L-phenylalanine
CN111304234A (zh) * 2020-02-27 2020-06-19 江南大学 一种适用于枯草芽孢杆菌的非天然氨基酸利用工具
CN113322267B (zh) * 2021-03-15 2024-01-05 天津大学 系统在提高非天然氨基酸的插入效率中的应用
WO2024091824A1 (en) 2022-10-26 2024-05-02 Ada Forsyth Institute, Inc. Differentiation and reprogramming of chondrocyte

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024939A (en) * 1987-07-09 1991-06-18 Genentech, Inc. Transient expression system for producing recombinant protein
AU6216199A (en) 1998-10-08 2000-04-26 Astrazeneca Ab Microfabricated cell injector
EP2177627B1 (en) 1999-02-23 2012-05-02 Caliper Life Sciences, Inc. Manipulation of microparticles in microfluidic systems
WO2002086075A2 (en) * 2001-04-19 2002-10-31 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
US8220494B2 (en) 2002-09-25 2012-07-17 California Institute Of Technology Microfluidic large scale integration
ATE429500T1 (de) 2002-10-16 2009-05-15 Scripps Research Inst Stellenspezifischer einbau von ketoaminosäuren in proteine
WO2004035605A2 (en) * 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
WO2004058946A2 (en) * 2002-12-22 2004-07-15 The Scripps Research Institute Protein arrays
MXPA05011127A (es) * 2003-04-17 2006-03-10 Scripps Research Inst Expansion del codigo genetico eucariontico.
US7888063B2 (en) * 2003-06-18 2011-02-15 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
EP1658366A4 (en) * 2003-07-07 2006-08-09 Scripps Research Inst COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES
US20060160175A1 (en) 2003-07-07 2006-07-20 The Scripps Research Institute Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof
PT1666604E (pt) 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
MXPA06004087A (es) 2003-10-14 2006-06-27 Scripps Research Inst Incorporacion especifica de sitio de amino acidos redox activos en proteinas.
US7709604B2 (en) 2003-12-18 2010-05-04 The Scripps Research Institute Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells
EP1774018A2 (en) * 2004-05-25 2007-04-18 The Scripps Research Institute Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination
CA2580840A1 (en) 2004-09-21 2006-03-30 The Scripps Research Institute In vivo incorporation of alkynyl amino acids into proteins in eubacteria
US20060134746A1 (en) 2004-09-21 2006-06-22 The Scripps Research Institute Adding photoregulated amino acids to the genetic code
EP1794312A4 (en) * 2004-09-22 2009-08-12 Scripps Research Inst LOCAL LABELING OF PROTEINS FOR NMR STUDIES
EP1809758A4 (en) * 2004-10-20 2009-04-01 Scripps Research Inst LOCAL IN VIVO INSTALLATION OF N-ACETYLGALACTOSAMINE AMINO ACIDS IN EU BACTERIA
EP2383340B1 (en) 2004-10-27 2014-07-16 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
AU2006304110B2 (en) 2005-10-12 2012-02-02 The Scripps Research Institute Selective posttranslational modification of phage-displayed polypeptides
US7960141B2 (en) 2006-03-09 2011-06-14 The Scripps Research Institute Systems for the expression of orthogonal translation components in eubacterial host cells
WO2007109035A2 (en) 2006-03-16 2007-09-27 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

Also Published As

Publication number Publication date
IL193394A0 (en) 2009-09-22
EP1991680A4 (en) 2009-10-21
AU2007223830A1 (en) 2007-09-13
US8357512B2 (en) 2013-01-22
EP1991680A2 (en) 2008-11-19
BRPI0709935A2 (pt) 2011-08-02
US20090181429A1 (en) 2009-07-16
JP5589186B2 (ja) 2014-09-17
US8198044B2 (en) 2012-06-12
JP2009529328A (ja) 2009-08-20
MX2008011470A (es) 2008-09-24
CN101400796B (zh) 2013-03-27
WO2007103490A3 (en) 2008-06-12
US7960141B2 (en) 2011-06-14
PT1991680E (pt) 2013-10-30
US20120252067A1 (en) 2012-10-04
EP1991680B1 (en) 2013-08-21
CN101400796A (zh) 2009-04-01
WO2007103490A2 (en) 2007-09-13
KR20080106430A (ko) 2008-12-05
US20070281335A1 (en) 2007-12-06
ES2432391T3 (es) 2013-12-03
CA2638763A1 (en) 2007-09-13

Similar Documents

Publication Publication Date Title
IL193394A0 (en) System for the expression of orthogonal translation components in eubacterial host cells
IL216990A0 (en) System for alterin virtual views
GB2449749B (en) Virtual address to physical address translation with support for page attributes
EP2044582A4 (en) DUCT SMOKE SYSTEM
ZA200807884B (en) Milling apparatus
ZA200806238B (en) Expression system
EP2215840A4 (en) VIRTUAL TABLE
GB2450260A8 (en) Techniques for interior coordinates
GB2436129A8 (en) Vapour power system
GB0625281D0 (en) Computer cooling system
GB0621234D0 (en) Expression system
GB0612673D0 (en) Computer system
GB0812557D0 (en) Docking system
GB0607121D0 (en) Formulation for skin moisturisation
GB0615378D0 (en) Computer system
GB0611007D0 (en) System host
GB0708550D0 (en) System host
TWI366087B (en) Computer system
AU308713S (en) Computer system unit
HK1136654A (en) Online computer-aided translation
GB0802670D0 (en) Protein methyltransferase
GB0613556D0 (en) Computer system
GB0614220D0 (en) Computer system
GB0613975D0 (en) Computer System
GB0610506D0 (en) Computer system