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PE63696A1 - Compuesto quimico - Google Patents

Compuesto quimico

Info

Publication number
PE63696A1
PE63696A1 PE1995287728A PE28772895A PE63696A1 PE 63696 A1 PE63696 A1 PE 63696A1 PE 1995287728 A PE1995287728 A PE 1995287728A PE 28772895 A PE28772895 A PE 28772895A PE 63696 A1 PE63696 A1 PE 63696A1
Authority
PE
Peru
Prior art keywords
formula
compound
refers
chemical compound
group
Prior art date
Application number
PE1995287728A
Other languages
English (en)
Inventor
Colin David Eldred
David George Allen
William Leonard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9426231.8A external-priority patent/GB9426231D0/en
Priority claimed from GBGB9503133.2A external-priority patent/GB9503133D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PE63696A1 publication Critical patent/PE63696A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE REFIERE AL COMPUESTO DE FORMULA I DONDE: X ES CH2-CH2 o CH=CH; Y REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO FENIL METILO, EN DONDE EL GRUPO FENILO OPCIONALMENTE ESTA SUSUTITUIDO POR UNO O MAS ATOMOS DE HALOGENO; TAMBIEN SE REFIERE A LOS PROCEDIMIENTOS DE PREPARACION TALES COMO: a) PARA EL COMPUESTO DE FORMULA I DONDE X ES CH=CH, HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON EL COMPUESTO DE FORMULA (III); b) DESPROTEGER DERIVADOS PROTEGIDOS DE COMPUESTOS DE FORMULA I; c) INTERCONVERSION DE UN COMPUESTO DE FORMULA I, EN OTRO COMPUESTO DE FORMULA I. ES USADO EN EL TRATAMIENTO DE UNA CONDICION QUE ES MEDIADA A TRAVES DEL COMPLEJO DE GLICOPROTEINA Gp IIb/IIIa
PE1995287728A 1994-12-23 1995-12-21 Compuesto quimico PE63696A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426231.8A GB9426231D0 (en) 1994-12-23 1994-12-23 Chemical compounds
GBGB9503133.2A GB9503133D0 (en) 1995-02-17 1995-02-17 Chemical compounds

Publications (1)

Publication Number Publication Date
PE63696A1 true PE63696A1 (es) 1997-01-11

Family

ID=26306268

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995287728A PE63696A1 (es) 1994-12-23 1995-12-21 Compuesto quimico

Country Status (21)

Country Link
US (1) US5861414A (es)
EP (1) EP0799223B1 (es)
JP (1) JPH10511375A (es)
CN (1) CN1175254A (es)
AP (1) AP9701010A0 (es)
AR (1) AR002260A1 (es)
AT (1) ATE181071T1 (es)
AU (1) AU704496B2 (es)
CO (1) CO4700291A1 (es)
DE (1) DE69510228T2 (es)
DK (1) DK0799223T3 (es)
ES (1) ES2132761T3 (es)
FI (1) FI972684A0 (es)
GR (1) GR3031027T3 (es)
IL (1) IL116480A0 (es)
NO (1) NO972887L (es)
NZ (1) NZ298400A (es)
PE (1) PE63696A1 (es)
SI (1) SI0799223T1 (es)
WO (1) WO1996020192A1 (es)
ZA (1) ZA951822B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760028A (en) * 1995-12-22 1998-06-02 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists
GB9613096D0 (en) * 1996-06-21 1996-08-28 Glaxo Group Ltd Medicaments
ES2325045T3 (es) 1996-10-14 2009-08-24 Bayer Healthcare Ag Nuevos derivados de pirazol heterociclilmetil sustituidos y su uso en el tratamiento de enfermedades cardiovasculares.
WO1998043962A1 (en) * 1997-03-28 1998-10-08 Du Pont Pharmaceuticals Company Heterocyclic integrin inhibitor prodrugs
PE20010306A1 (es) * 1999-07-02 2001-03-29 Agouron Pharma Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
TWI262914B (en) * 1999-07-02 2006-10-01 Agouron Pharma Compounds and pharmaceutical compositions for inhibiting protein kinases
US7141581B2 (en) * 1999-07-02 2006-11-28 Agouron Pharmaceuticals, Inc. Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
YU54202A (sh) 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
CN1281605C (zh) * 2000-12-22 2006-10-25 惠氏公司 作为5－羟色胺－6配基的杂环基－吲唑或氮杂吲唑化合物
US7008953B2 (en) 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
GB0400895D0 (en) * 2004-01-15 2004-02-18 Smithkline Beecham Corp Chemical compounds
TW200616967A (en) * 2004-06-24 2006-06-01 Smithkline Beecham Corp Novel indazole carboxamides and their use
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681382A (en) * 1969-02-07 1972-08-01 Ciba Geigy Corp 3-aminoindazoles
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
US5219867A (en) * 1991-12-16 1993-06-15 Research Corporation Technologies, Inc. Platelet aggregation inhibitory agents
JPH05255308A (ja) * 1992-03-11 1993-10-05 Ajinomoto Co Inc ピペリジン誘導体
JP3194777B2 (ja) * 1992-03-13 2001-08-06 学校法人東京薬科大学 立体選択的ｄ−リボフラノシル化法
JPH06234633A (ja) * 1993-02-10 1994-08-23 Ajinomoto Co Inc アミン誘導体およびこれを含有する抗血小板剤

Also Published As

Publication number Publication date
WO1996020192A1 (en) 1996-07-04
GR3031027T3 (en) 1999-12-31
US5861414A (en) 1999-01-19
AP9701010A0 (en) 1997-07-31
ES2132761T3 (es) 1999-08-16
ZA951822B (en) 1996-09-26
DE69510228D1 (de) 1999-07-15
DK0799223T3 (da) 1999-12-27
FI972684A7 (fi) 1997-06-19
ATE181071T1 (de) 1999-06-15
NO972887L (no) 1997-08-20
EP0799223A1 (en) 1997-10-08
FI972684L (fi) 1997-06-19
DE69510228T2 (de) 1999-11-04
IL116480A0 (en) 1996-03-31
FI972684A0 (fi) 1997-06-19
SI0799223T1 (en) 1999-10-31
AU4387896A (en) 1996-07-19
CN1175254A (zh) 1998-03-04
AU704496B2 (en) 1999-04-22
NZ298400A (en) 1999-10-28
EP0799223B1 (en) 1999-06-09
AR002260A1 (es) 1998-03-11
CO4700291A1 (es) 1998-12-29
JPH10511375A (ja) 1998-11-04
NO972887D0 (no) 1997-06-20

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Legal Events

Date Code Title Description
FX Voluntary withdrawal