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ATE181071T1 - Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel - Google Patents

Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel

Info

Publication number
ATE181071T1
ATE181071T1 AT95942704T AT95942704T ATE181071T1 AT E181071 T1 ATE181071 T1 AT E181071T1 AT 95942704 T AT95942704 T AT 95942704T AT 95942704 T AT95942704 T AT 95942704T AT E181071 T1 ATE181071 T1 AT E181071T1
Authority
AT
Austria
Prior art keywords
acid derivatives
piperidineacetic acid
fibrinogen antagonists
fibrinogen
antagonists
Prior art date
Application number
AT95942704T
Other languages
English (en)
Inventor
David George Allen
Colin David Eldred
William Leonard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9426231.8A external-priority patent/GB9426231D0/en
Priority claimed from GBGB9503133.2A external-priority patent/GB9503133D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE181071T1 publication Critical patent/ATE181071T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95942704T 1994-12-23 1995-12-21 Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel ATE181071T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426231.8A GB9426231D0 (en) 1994-12-23 1994-12-23 Chemical compounds
GBGB9503133.2A GB9503133D0 (en) 1995-02-17 1995-02-17 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE181071T1 true ATE181071T1 (de) 1999-06-15

Family

ID=26306268

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95942704T ATE181071T1 (de) 1994-12-23 1995-12-21 Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel

Country Status (21)

Country Link
US (1) US5861414A (de)
EP (1) EP0799223B1 (de)
JP (1) JPH10511375A (de)
CN (1) CN1175254A (de)
AP (1) AP9701010A0 (de)
AR (1) AR002260A1 (de)
AT (1) ATE181071T1 (de)
AU (1) AU704496B2 (de)
CO (1) CO4700291A1 (de)
DE (1) DE69510228T2 (de)
DK (1) DK0799223T3 (de)
ES (1) ES2132761T3 (de)
FI (1) FI972684L (de)
GR (1) GR3031027T3 (de)
IL (1) IL116480A0 (de)
NO (1) NO972887L (de)
NZ (1) NZ298400A (de)
PE (1) PE63696A1 (de)
SI (1) SI0799223T1 (de)
WO (1) WO1996020192A1 (de)
ZA (1) ZA951822B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760028A (en) * 1995-12-22 1998-06-02 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists
GB9613096D0 (en) * 1996-06-21 1996-08-28 Glaxo Group Ltd Medicaments
US6166027A (en) 1996-10-14 2000-12-26 Bayer Aktiengesellschaft Heterocyclylmethyl-substituted pyrazole derivatives and their use for treating cardiovascular diseases
AU6780398A (en) 1997-03-28 1998-10-22 Du Pont Merck Pharmaceutical Company, The Heterocyclic integrin inhibitor prodrugs
US7141581B2 (en) * 1999-07-02 2006-11-28 Agouron Pharmaceuticals, Inc. Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
TWI262914B (en) 1999-07-02 2006-10-01 Agouron Pharma Compounds and pharmaceutical compositions for inhibiting protein kinases
PE20010306A1 (es) * 1999-07-02 2001-03-29 Agouron Pharma Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
MXPA03005432A (es) * 2000-12-22 2003-09-10 Wyeth Corp Compuestos de heterociclilindazol y -azaindazol como ligandos de 5-hidroxitriptamina-6.
US7008953B2 (en) 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
GB0400895D0 (en) * 2004-01-15 2004-02-18 Smithkline Beecham Corp Chemical compounds
TW200616967A (en) * 2004-06-24 2006-06-01 Smithkline Beecham Corp Novel indazole carboxamides and their use
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681382A (en) * 1969-02-07 1972-08-01 Ciba Geigy Corp 3-aminoindazoles
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
US5219867A (en) * 1991-12-16 1993-06-15 Research Corporation Technologies, Inc. Platelet aggregation inhibitory agents
JPH05255308A (ja) * 1992-03-11 1993-10-05 Ajinomoto Co Inc ピペリジン誘導体
JP3194777B2 (ja) * 1992-03-13 2001-08-06 学校法人東京薬科大学 立体選択的d−リボフラノシル化法
JPH06234633A (ja) * 1993-02-10 1994-08-23 Ajinomoto Co Inc アミン誘導体およびこれを含有する抗血小板剤

Also Published As

Publication number Publication date
GR3031027T3 (en) 1999-12-31
EP0799223A1 (de) 1997-10-08
SI0799223T1 (en) 1999-10-31
ES2132761T3 (es) 1999-08-16
CO4700291A1 (es) 1998-12-29
AP9701010A0 (en) 1997-07-31
DE69510228T2 (de) 1999-11-04
IL116480A0 (en) 1996-03-31
AR002260A1 (es) 1998-03-11
NZ298400A (en) 1999-10-28
NO972887L (no) 1997-08-20
AU4387896A (en) 1996-07-19
NO972887D0 (no) 1997-06-20
EP0799223B1 (de) 1999-06-09
WO1996020192A1 (en) 1996-07-04
DK0799223T3 (da) 1999-12-27
AU704496B2 (en) 1999-04-22
ZA951822B (en) 1996-09-26
FI972684A0 (fi) 1997-06-19
US5861414A (en) 1999-01-19
FI972684A7 (fi) 1997-06-19
FI972684L (fi) 1997-06-19
DE69510228D1 (de) 1999-07-15
PE63696A1 (es) 1997-01-11
CN1175254A (zh) 1998-03-04
JPH10511375A (ja) 1998-11-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee