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PE55396A1 - Formulacion de cafeina con retardo sostenido - Google Patents

Formulacion de cafeina con retardo sostenido

Info

Publication number
PE55396A1
PE55396A1 PE1995286458A PE28645895A PE55396A1 PE 55396 A1 PE55396 A1 PE 55396A1 PE 1995286458 A PE1995286458 A PE 1995286458A PE 28645895 A PE28645895 A PE 28645895A PE 55396 A1 PE55396 A1 PE 55396A1
Authority
PE
Peru
Prior art keywords
caffeine
layer
formulation
internal layer
stimulant
Prior art date
Application number
PE1995286458A
Other languages
English (en)
Inventor
Marc Y A Enslen
Pierre Tachon
Francoise Chauffard
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of PE55396A1 publication Critical patent/PE55396A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

SE REFIERE A LA COMPOSICION PARA LA LIBERACION CONTROLADA DE UN ESTIMULANTE DE XANTINA O DERIVADO DE XANTINA, LA CUAL COMPRENDE MICROPARTICULAS QUE INCLUYEN UN NUCLEO (1) DE UN MATERIAL ORGANICO TAL COMO UN POLISACARIDO, AZUCAR O UN DERIVADO DE AZUCAR Y OPCIONALMENTE UN DILUYENTE COMO ALMIDON; CAPAS INTERIOR Y EXTERIOR (2) DE LA MATRIZ Y UN RECUBRIMIENTO INTERMEDIO (5); LA CAPA INTERNA (2) ILUSTRA LA PARTICULA DE CAFEINA (3) Y EL LIGANTE DE UN MATERIAL HIDROSOLUBLE (4) TAL COMO UN POLIMERO SINTETICO, ESTA CAPA INCLUYE ENTRE 55% Y 95% DE LA CANTIDAD DE CAFEINA DESTINADA A LA FORMULACION; LA CAPA (5) REPRESENTA EL RECUBRIMIENTO TAL COMO GOMA LACA Y TALCO QUE FUNCIONA COMO UN PROTECTOR PARA REDUCIR LA LIBERACION DE CAFEINA DESDE LA CAPA INTERNA (2); LA CAPA EXTERNA (6) ES DE COMPOSICION SIMILAR A LA (2), CON LA EXCEPCION QUE ES APLICADA A UN MENOR ESPESOR QUE LA CAPA INTERNA Y CONTIENE DE 5% A 45% DEL TOTAL DEL ESTIMULANTE EN LA FORMULACION. ES USADO PARA AUMENTAR EL ESTADO DE ALERTA DE UN INDIVIDUO
PE1995286458A 1994-12-16 1995-12-05 Formulacion de cafeina con retardo sostenido PE55396A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/357,689 US5744164A (en) 1994-12-16 1994-12-16 Sustained release microparticulate caffeine formulation

Publications (1)

Publication Number Publication Date
PE55396A1 true PE55396A1 (es) 1996-12-24

Family

ID=23406640

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995286458A PE55396A1 (es) 1994-12-16 1995-12-05 Formulacion de cafeina con retardo sostenido

Country Status (21)

Country Link
US (2) US5744164A (es)
EP (2) EP0716853A1 (es)
JP (1) JPH10510529A (es)
AR (1) AR002947A1 (es)
AT (1) ATE201986T1 (es)
AU (1) AU694810B2 (es)
CA (1) CA2208149C (es)
CO (1) CO4600671A1 (es)
DE (1) DE69521328T2 (es)
DK (1) DK0789562T3 (es)
ES (1) ES2158956T3 (es)
GR (1) GR3036501T3 (es)
HK (1) HK1000878A1 (es)
IL (1) IL116066A (es)
NZ (1) NZ295245A (es)
PE (1) PE55396A1 (es)
PT (1) PT789562E (es)
RU (1) RU2144353C1 (es)
TR (1) TR199501560A2 (es)
WO (1) WO1996018389A1 (es)
ZA (1) ZA9510687B (es)

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US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US20020159956A1 (en) * 1999-04-06 2002-10-31 Ream Ronald L. Over-coated chewing gum formulations
US7935362B2 (en) * 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
WO2001021147A1 (en) * 1999-09-20 2001-03-29 Mastercare Diet and weight control gum and sucker
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US7115297B2 (en) 2000-02-22 2006-10-03 Suzanne Jaffe Stillman Nutritionally fortified liquid composition with added value delivery systems/elements/additives
US8178150B2 (en) 2000-02-22 2012-05-15 Suzanne Jaffe Stillman Water containing soluble fiber
US7892586B2 (en) 2001-02-22 2011-02-22 Suzanne Jaffe Stillman Water containing soluble fiber
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
RU2166945C1 (ru) * 2000-08-08 2001-05-20 Ефимова Лариса Степановна Радиосенсибилизирующее вещество для лечения онкологических заболеваний
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
US7897141B2 (en) * 2002-04-01 2011-03-01 Drexel University Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof
US20030220351A1 (en) * 2002-05-24 2003-11-27 Gilbert Gonzales Enteric coated caffeine tablet
EP1565062A1 (en) * 2002-11-25 2005-08-24 Phares Pharmaceutical Research N.V. Confectionery composition
US20050181044A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements, green coffee extract
US20050220875A1 (en) * 2004-03-31 2005-10-06 Agency For Science, Technology And Research Sustained-release tablet formulation
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US8486452B2 (en) * 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8044021B2 (en) * 2007-09-20 2011-10-25 Abbott Cardiovascular Systems Inc. Sustained release of apo A-I mimetic peptides and methods of treatment
US8101565B2 (en) * 2007-09-20 2012-01-24 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US7985728B1 (en) 2007-09-20 2011-07-26 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US9173890B2 (en) * 2007-09-20 2015-11-03 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US7985727B1 (en) 2007-09-20 2011-07-26 Abbott Cardiovascular Systems Inc. Apo A-I mimetic peptides and methods of treatment
AU2010211985A1 (en) * 2009-01-22 2011-08-11 Abbott Healthcare Private Limited Chronotherapeutic pharmaceutical composition
US8545892B2 (en) 2009-06-26 2013-10-01 Nano Pharmaceutical Laboratories, Llc Sustained release beads and suspensions including the same for sustained delivery of active ingredients
US8992898B2 (en) 2010-04-17 2015-03-31 Shannon Elizabeth Klingman Antiperspirants and deodorants
US20160128943A1 (en) * 2013-06-04 2016-05-12 KVK-Tech, Inc. Controlled release caffeine dosage forms
CA2978593A1 (en) 2015-01-12 2016-07-21 Nano Pharmaceutical Laboratories Llc Layered sustained-release microbeads and methods of making the same
KR101644154B1 (ko) * 2015-09-08 2016-07-29 주식회사 스킨앤테크 수용성 카페인 및 그 제조방법
US10582716B1 (en) 2019-06-14 2020-03-10 Lennham Pharmaceuticals, Inc. Deuterated caffeine and uses thereof
US12194046B2 (en) * 2021-03-09 2025-01-14 Lennham Pharmaceuticals, Inc. D9-caffeine compositions and uses thereof
JP2024525962A (ja) * 2021-07-30 2024-07-12 寶齡富錦生技股▲ふん▼有限公司 放出制御型経口製剤及びその調製方法

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Also Published As

Publication number Publication date
ATE201986T1 (de) 2001-06-15
EP0789562A1 (en) 1997-08-20
TR199501560A2 (tr) 1996-07-21
IL116066A (en) 2000-10-31
CO4600671A1 (es) 1998-05-08
CA2208149C (en) 2007-03-27
HK1000878A1 (en) 2001-10-26
US5700484A (en) 1997-12-23
PT789562E (pt) 2001-10-30
AU694810B2 (en) 1998-07-30
NZ295245A (en) 1999-01-28
EP0789562B1 (en) 2001-06-13
DE69521328D1 (de) 2001-07-19
EP0716853A1 (en) 1996-06-19
RU2144353C1 (ru) 2000-01-20
JPH10510529A (ja) 1998-10-13
CA2208149A1 (en) 1996-06-20
AR002947A1 (es) 1998-05-27
IL116066A0 (en) 1996-01-31
ZA9510687B (en) 1996-07-03
AU3854295A (en) 1996-07-03
DE69521328T2 (de) 2002-01-17
US5744164A (en) 1998-04-28
WO1996018389A1 (en) 1996-06-20
DK0789562T3 (da) 2001-09-03
GR3036501T3 (en) 2001-11-30
ES2158956T3 (es) 2001-09-16

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