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PE27897A1 - Variantes bpn` que tienen absorbion disminuida e hidrolisis aumentada, en donde se sustituye una o mas regiones de enlace - Google Patents

Variantes bpn` que tienen absorbion disminuida e hidrolisis aumentada, en donde se sustituye una o mas regiones de enlace

Info

Publication number
PE27897A1
PE27897A1 PE1995265539A PE26553995A PE27897A1 PE 27897 A1 PE27897 A1 PE 27897A1 PE 1995265539 A PE1995265539 A PE 1995265539A PE 26553995 A PE26553995 A PE 26553995A PE 27897 A1 PE27897 A1 PE 27897A1
Authority
PE
Peru
Prior art keywords
bpn
absorbion
variants
decreased
replaced
Prior art date
Application number
PE1995265539A
Other languages
English (en)
Inventor
Chanchal Kumar Ghosh
Donn Nelton Rubingh
Iii Philip Frederick Brode
Bobby Lee Barnett
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of PE27897A1 publication Critical patent/PE27897A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609—Protease or amylase in solid compositions only
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE REFIERE A UNA ENZIMA DE SUBTILISINA, DE FORMULA I, LA CUAL SE ENCUENTRA MODIFICADA EN UNA O MAS POSICIONES DE CINCO U OPCIONALMENTE SEIS REGIONES DE SECUENCIAS QUE COMPRENDEN: A) DEL 59 AL 66; B) DEL 95 AL 107; C) DEL 126 AL 133; D) DEL 154 AL 167; E) DEL 187 AL 191; F) DEL 199 AL 200; DONDE EL AMINOACIDO QUE SUSTITUYE AL DEL TIPO NATURAL ES PREFERENTEMENTE UN AMINOACIDO NEUTRO O MAS PREFERENTEMENTEMENTE UNO CARGADO NEGATIVAMENTE, CONFORME A LA TABLA (II). TAMBIEN SE REFIERE AL GEN BPN` MUTANTE QUE CODIFICA A LA VARIANTE BPN'(ENZIMA SUBTILISINA MODIFICADA). ESTAS MODIFICACIONES EN LAS REGIONES DE ENLACE LE PERMITEN UNA ABSORCION CATALITICAMENTE MAS PRODUCTIVA PARA LOS SUSTRATOS UNIDOS A LA SUPERFICIE (SUCIOS DE PROTEINA/PEPTIDOS), ESTO ES, QUE POSEEN UNA MEJOR EFICACIA LIMPIADORA. SIENDO USADA EN LAS COMPOSICIONES LIMPIADORAS PARA SUPERFICIES DURAS, PARA TEXTILES O LIMPIADORAS BUCALES, ENTRE OTRAS APLICACIONES
PE1995265539A 1994-05-02 1995-04-03 Variantes bpn` que tienen absorbion disminuida e hidrolisis aumentada, en donde se sustituye una o mas regiones de enlace PE27897A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23793994A 1994-05-02 1994-05-02
US28746194A 1994-08-11 1994-08-11
US08/394,011 US6436690B1 (en) 1993-09-15 1995-03-03 BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted

Publications (1)

Publication Number Publication Date
PE27897A1 true PE27897A1 (es) 1997-08-13

Family

ID=27399035

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995265539A PE27897A1 (es) 1994-05-02 1995-04-03 Variantes bpn` que tienen absorbion disminuida e hidrolisis aumentada, en donde se sustituye una o mas regiones de enlace

Country Status (13)

Country Link
US (1) US6436690B1 (es)
EP (1) EP0758388A1 (es)
JP (1) JPH09511652A (es)
CN (1) CN1151761A (es)
AU (1) AU2159195A (es)
BR (1) BR9507597A (es)
CA (1) CA2189426C (es)
CZ (1) CZ321696A3 (es)
HU (1) HUT75559A (es)
IL (1) IL113048A0 (es)
MX (1) MX9605357A (es)
PE (1) PE27897A1 (es)
WO (1) WO1995030010A1 (es)

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IL113048A0 (en) 1995-06-29
CA2189426A1 (en) 1995-11-09
CN1151761A (zh) 1997-06-11
MX9605357A (es) 1997-12-31
WO1995030010A1 (en) 1995-11-09
HUT75559A (en) 1997-05-28
EP0758388A1 (en) 1997-02-19
HU9603031D0 (en) 1997-01-28
US6436690B1 (en) 2002-08-20
JPH09511652A (ja) 1997-11-25
CA2189426C (en) 2002-09-17
AU2159195A (en) 1995-11-29
BR9507597A (pt) 1997-10-07

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