PE22996A1 - Derivados 5-substituidos del acido micofenolico - Google Patents
Derivados 5-substituidos del acido micofenolicoInfo
- Publication number
- PE22996A1 PE22996A1 PE1995262077A PE26207795A PE22996A1 PE 22996 A1 PE22996 A1 PE 22996A1 PE 1995262077 A PE1995262077 A PE 1995262077A PE 26207795 A PE26207795 A PE 26207795A PE 22996 A1 PE22996 A1 PE 22996A1
- Authority
- PE
- Peru
- Prior art keywords
- halogen
- lower alkyl
- och3
- alkyl
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I DONDE: R1 ES H o C(O)R10 Y R10 ES ALQUILO INFERIOR, ARILO O NH ARILO. Z ES SELECCIONADO DE ZA, ZB, ZC, ZD, ZE, ZF, ZG, ZH, PARTICIPANDO EN ZA, Z1, Z2, Z3, Z4, Y G; EN ZB Z5, Z8, D1, D2 y G; EN ZC, Z5, Z8 y G; EN ZD, D3 Y G; EN ZE, Z5, Z6, Z7 y G; EN ZF, Z1 y G; EN ZG, Z2, Z3, Z4, D3 y G; LOGRANDOSE LOS COMPUESTOS DE MAYOR IMPORTANCIA CUANDO: A)R1 ES H, B)R1 ES H y G ES OH, C)R1 ES H y G ES MORFOLINOETOXI, Y DONDE Z1 ES H, ALQUILO INFERIOR, HALOGENO o CF3, Z2 ES H, OH, ALQUILO INFERIOR, ALCOXI INFERIOR ENTRE OTROS, Z3 ES H, OH, ALQUILO INFERIOR, P(O)(OCH3)2, P(O)(OH)(OCH3), NHZ11(Z11 ES H, ALQUILO, ACILO ETC), Z4 ES H, OH, ALQUILO INFERIOR, HALOGENO, O FENILO SIEMPRE QUE Z4 NO SEA OH o HALOGENO CUANDO Z3 ES OH, HALOGENO, P(O)(OCH3)2 ENTRE OTROS, Z3 Y Z4 TOMADOS EN CONJUNTO CON EL ATOMO DE CARBONO CON EL QUE ESTA LIGADO FORMAN CICLOALQUILOS DE 3 A 5 ATOMOS DE CARBONO, G ES OH, ALCOXI INFERIOR, TIOALQUILO INFERIOR ENTRE OTROS, Z5 ES H, ALQUILO INFERIOR, Z8 ES H, ALQUILO INFERIOR O FORMA DOBLE UNION CON D2, D1 Y D2 JUNTO CON LOS ATOMOS DE CARBONO ADYACENTES FORMAN SUSTITUTO OPCIONAL SATURADO O NO, D3 ES CH2 o CH CH2, Z6 Y Z7 SON H, ALQUILO INFERIOR HALOGENO ENTRE OTROS, ESTAS DROGAS SE CARACTERIZAN POR SU USO EN DESORDENES INMUNOLOGICOS, INFLAMATORIOS ENTRE ETC
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/198,749 US5493030A (en) | 1994-02-18 | 1994-02-18 | 5-substituted derivatives of mycophenolic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE22996A1 true PE22996A1 (es) | 1996-06-04 |
Family
ID=22734662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1995262077A PE22996A1 (es) | 1994-02-18 | 1995-02-16 | Derivados 5-substituidos del acido micofenolico |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US5493030A (es) |
| EP (1) | EP0745073B1 (es) |
| JP (1) | JPH09509174A (es) |
| CN (1) | CN1141038A (es) |
| AT (1) | ATE194608T1 (es) |
| AU (1) | AU1875495A (es) |
| BR (1) | BR9506819A (es) |
| CA (1) | CA2183530A1 (es) |
| CO (1) | CO4340734A1 (es) |
| DE (1) | DE69517957T2 (es) |
| DK (1) | DK0745073T3 (es) |
| ES (1) | ES2149971T3 (es) |
| FI (1) | FI963218L (es) |
| GR (1) | GR3033864T3 (es) |
| GT (1) | GT199500007A (es) |
| HR (1) | HRP950070B1 (es) |
| IL (2) | IL124139A (es) |
| IS (1) | IS4264A (es) |
| MX (1) | MX9603478A (es) |
| MY (1) | MY112804A (es) |
| PE (1) | PE22996A1 (es) |
| PH (1) | PH31441A (es) |
| PT (1) | PT745073E (es) |
| SI (1) | SI0745073T1 (es) |
| SV (1) | SV1995000007A (es) |
| TW (1) | TW384288B (es) |
| UY (2) | UY23910A1 (es) |
| WO (1) | WO1995022538A1 (es) |
| ZA (1) | ZA951299B (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514979B1 (en) * | 1999-03-03 | 2003-02-04 | University Of Maryland Biotechnology Institute | Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor |
| US6811998B2 (en) * | 1999-06-25 | 2004-11-02 | Roche Diagnostics Operations, Inc. | Conjugates of uncompetitive inhibitors of inosine monophosphate dehydrogenase |
| US7214754B2 (en) * | 1999-12-13 | 2007-05-08 | Ppg Industries Ohio, Inc. | Polymerizable polyol (allyl carbonate) compositions |
| US7179791B2 (en) | 2001-01-11 | 2007-02-20 | Duke University | Inhibiting GS-FDH to modulate NO bioactivity |
| US20040127435A1 (en) * | 2002-08-02 | 2004-07-01 | Regents Of The University Of California | Uses for inhibitors of inosine monophosphate dehydrogenase |
| US20050261237A1 (en) * | 2003-04-25 | 2005-11-24 | Boojamra Constantine G | Nucleoside phosphonate analogs |
| US20090247488A1 (en) * | 2003-04-25 | 2009-10-01 | Carina Cannizzaro | Anti-inflammatory phosphonate compounds |
| WO2004096287A2 (en) * | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
| US7452901B2 (en) * | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
| US7432261B2 (en) * | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
| WO2004096285A2 (en) * | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Anti-infective phosphonate conjugates |
| WO2004096234A2 (en) * | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Kinase inhibitor phosphonate conjugates |
| US7407965B2 (en) * | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
| CN101410120A (zh) * | 2003-04-25 | 2009-04-15 | 吉里德科学公司 | 抗炎的膦酸酯化合物 |
| WO2005002626A2 (en) | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
| US7470724B2 (en) * | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
| PL1628685T3 (pl) | 2003-04-25 | 2011-05-31 | Gilead Sciences Inc | Przeciwwirusowe analogi fosfonianowe |
| US20050187170A1 (en) * | 2003-06-16 | 2005-08-25 | Biocryst Pharmaceuticals, Inc. | Enhancing the efficiency of RNA polymerase inhibitors by using inosine monophosphate dehydrogenase inhibitors |
| PL1667987T3 (pl) * | 2003-09-11 | 2009-01-30 | Sandoz Ag | Sposób wytwarzania mykofenolanu mofetylu |
| WO2005044308A1 (en) * | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
| WO2005044279A1 (en) * | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Purine nucleoside phosphonate conjugates |
| BRPI0418031A (pt) * | 2003-12-22 | 2007-04-17 | Gilead Sciences Inc | inibidores de quinase fosfonato-substituìdos |
| EP1706405B1 (en) * | 2003-12-22 | 2009-03-04 | Gilead Sciences, Inc. | 4'-substituted carbovir- and abacavir-derivatives as well as related compounds with hiv and hcv antiviral activity |
| US20050153990A1 (en) * | 2003-12-22 | 2005-07-14 | Watkins William J. | Phosphonate substituted kinase inhibitors |
| EP1768662A2 (en) | 2004-06-24 | 2007-04-04 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
| US8318701B2 (en) | 2004-07-27 | 2012-11-27 | Gilead Sciences, Inc. | Phosphonate analogs of HIV inhibitor compounds |
| CA2585353A1 (en) * | 2004-10-26 | 2006-05-04 | Gilead Sciences, Inc. | Phosphonate derivatives of mycophenolic acid |
| US20080161324A1 (en) * | 2006-09-14 | 2008-07-03 | Johansen Lisa M | Compositions and methods for treatment of viral diseases |
| CN101422424B (zh) * | 2007-10-31 | 2012-10-24 | 王世亮 | 霉酚酸类药物植入剂及其制备方法和应用 |
| EA018308B1 (ru) * | 2008-07-08 | 2013-07-30 | Джилид Сайэнс, Инк. | Соли соединений ингибиторов вич |
| WO2013044028A2 (en) * | 2011-09-21 | 2013-03-28 | Texas A&M University System | Mycophenolic acid analogues as anti-tumor chemosensitizing agents |
| CN105271935B (zh) * | 2015-11-03 | 2017-06-30 | 陶祖岐 | 一种生活垃圾制成的装饰板和包装箱板 |
| US10603299B2 (en) | 2016-06-02 | 2020-03-31 | Steven Baranowitz | Prevention and treatment of viral infections |
| CA3026241A1 (en) | 2016-06-02 | 2017-12-07 | Steven Baranowitz | Prevention and treatment of viral infections |
| US12011429B2 (en) | 2016-06-02 | 2024-06-18 | Steven Baranowitz | Prevention and treatment of viral infections |
| ES2892402T3 (es) | 2017-08-01 | 2022-02-04 | Gilead Sciences Inc | Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2-il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3825571A (en) * | 1971-07-31 | 1974-07-23 | Chugai Pharmaceutical Co Ltd | Mycophenolic acid derivatives |
| JPS5542995B2 (es) * | 1972-02-24 | 1980-11-04 | ||
| JPS5529994B2 (es) * | 1972-03-02 | 1980-08-07 | ||
| US4479005A (en) * | 1982-12-16 | 1984-10-23 | The Dow Chemical Company | Selective preparation of isomers and enantiomers of cyclopropane carboxylic acids |
| US4515956A (en) * | 1982-12-16 | 1985-05-07 | The Dow Chemical Company | Selective preparation of isomers and enantiomers of cyclopropane carboxylic acids |
| US4686234A (en) * | 1985-11-27 | 1987-08-11 | Syntex (U.S.A) Inc. | Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis |
| US4725622A (en) * | 1986-01-23 | 1988-02-16 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
| US4959387A (en) * | 1986-01-23 | 1990-09-25 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
| US5231179A (en) * | 1986-01-27 | 1993-07-27 | Sumitomo Pharmaceuticals Company, Limited | Heterocyclic compounds and their production |
| US4748173A (en) * | 1987-01-30 | 1988-05-31 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions |
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
| US4727069A (en) * | 1987-01-30 | 1988-02-23 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid, derivatives thereof and pharmaceutical compositions |
| US4861776A (en) * | 1987-01-30 | 1989-08-29 | Syntex (U.S.A) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof, compositions and use |
| JPH0637486B2 (ja) * | 1988-05-18 | 1994-05-18 | 三共株式会社 | 新規抗生物質フタレキシンおよびその製造法 |
| US4940797A (en) * | 1989-03-23 | 1990-07-10 | Merck & Co., Inc. | Process for synthesis of FK-506 C10-C18 intermediates |
| US5155228A (en) * | 1989-03-23 | 1992-10-13 | Merck & Co., Inc. | FK-506 C10-C18 process intermediates |
| US5068345A (en) * | 1989-10-30 | 1991-11-26 | Eastman Kodak Company | Oxazolidinone aldol adduct |
| US5247083A (en) * | 1992-07-10 | 1993-09-21 | Syntex (U.S.A.) Inc. | Direct esterification of mycophenolic acid |
-
1994
- 1994-02-18 US US08/198,749 patent/US5493030A/en not_active Expired - Lifetime
-
1995
- 1995-02-15 PH PH49980A patent/PH31441A/en unknown
- 1995-02-16 UY UY23910A patent/UY23910A1/es not_active IP Right Cessation
- 1995-02-16 ES ES95910984T patent/ES2149971T3/es not_active Expired - Lifetime
- 1995-02-16 EP EP95910984A patent/EP0745073B1/en not_active Expired - Lifetime
- 1995-02-16 AT AT95910984T patent/ATE194608T1/de not_active IP Right Cessation
- 1995-02-16 CA CA002183530A patent/CA2183530A1/en not_active Abandoned
- 1995-02-16 HR HR08/198,749 patent/HRP950070B1/xx not_active IP Right Cessation
- 1995-02-16 MX MX9603478A patent/MX9603478A/es unknown
- 1995-02-16 IS IS4264A patent/IS4264A/is unknown
- 1995-02-16 CN CN95191654A patent/CN1141038A/zh active Pending
- 1995-02-16 JP JP7521868A patent/JPH09509174A/ja not_active Ceased
- 1995-02-16 IL IL12413995A patent/IL124139A/xx not_active IP Right Cessation
- 1995-02-16 FI FI963218A patent/FI963218L/fi unknown
- 1995-02-16 MY MYPI95000420A patent/MY112804A/en unknown
- 1995-02-16 IL IL11266595A patent/IL112665A/xx not_active IP Right Cessation
- 1995-02-16 DK DK95910984T patent/DK0745073T3/da active
- 1995-02-16 WO PCT/US1995/001787 patent/WO1995022538A1/en not_active Ceased
- 1995-02-16 DE DE69517957T patent/DE69517957T2/de not_active Expired - Fee Related
- 1995-02-16 BR BR9506819A patent/BR9506819A/pt active Search and Examination
- 1995-02-16 PT PT95910984T patent/PT745073E/pt unknown
- 1995-02-16 CO CO95005930A patent/CO4340734A1/es unknown
- 1995-02-16 SV SV1995000007A patent/SV1995000007A/es not_active Application Discontinuation
- 1995-02-16 AU AU18754/95A patent/AU1875495A/en not_active Abandoned
- 1995-02-16 SI SI9530434T patent/SI0745073T1/xx unknown
- 1995-02-16 ZA ZA951299A patent/ZA951299B/xx unknown
- 1995-02-16 PE PE1995262077A patent/PE22996A1/es not_active Application Discontinuation
- 1995-02-16 TW TW084101398A patent/TW384288B/zh not_active IP Right Cessation
- 1995-02-17 GT GT199500007A patent/GT199500007A/es unknown
- 1995-06-06 US US08/483,042 patent/US5633279A/en not_active Expired - Lifetime
-
1998
- 1998-11-23 UY UY25262A patent/UY25262A1/es not_active Application Discontinuation
-
2000
- 2000-07-13 GR GR20000401101T patent/GR3033864T3/el not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE22996A1 (es) | Derivados 5-substituidos del acido micofenolico | |
| PE23096A1 (es) | Acido micofenolico 6-substituido y derivados | |
| PT96890A (pt) | Processo para a preparacao de novos derivados com estrutura naftalenica e de composicoes farmaceuticas que os contem | |
| ATE11535T1 (de) | N-heteroaryl-alkylendiamine, verfahren zu ihrer herstellung sowie ihre verwendung. | |
| PT75471A (fr) | Procede de preparation d'ethers tricycliques | |
| ATE23722T1 (de) | Feuerhemmende zusammensetzungen. | |
| CO5050332A1 (es) | Composiciones fungicidas que comprenden 2-metoxibenzofenonas | |
| ES8503355A1 (es) | Procedimiento de preparacion de nuevas sales de derivados organofosforados | |
| ES546091A0 (es) | Un procedimiento para la obtencion de derivados de triptamina. | |
| ES2040366T3 (es) | Procedimiento de preparacion de nuevos derivados de 1-(bencilpiperidino)2-propanol. | |
| DE3675226D1 (de) | Triazinderivate, verfahren zur herstellung der derivate und die derivate als wirksamen bestandteil enthaltende herbizide. | |
| DK0530335T3 (da) | Disphosphonsyrederivater som mellemprodukter til fremstillingen af diphosphinligander | |
| SE7903450L (sv) | Nya substituerade 1,3-diaryl-2-imino-imidazolidiner och -2-imino-hexahydro-pyrimidiner och sett for framstellning derav | |
| ATE210642T1 (de) | 2-substituierte vitamin-d3-derivate | |
| ES545575A0 (es) | Un procedimiento para la preparacion de tiazolidinas | |
| ES2071759T3 (es) | Compuestos de maleimida y fungicidas que los contienen. | |
| DK415789A (da) | Tetracykliske antidepressive midler | |
| ES511753A0 (es) | Un procedimiento para la preparacion de derivados de sucrosa'4-halo-sustituidos. | |
| ES8705421A1 (es) | Un procedimiento para la preparacion de 4-amino-2-fenil-quinolinas | |
| AR248274A1 (es) | Derivados de benzotiazoles sustituidos, procedimientos para producirlos, productos intermedios para dicho procedimiento y composiciones herbicidas que los contienen. | |
| KR850001213A (ko) | 이미다조[1,5-a] 피리미딘 유도체의 제조방법 | |
| ES8604219A1 (es) | Un procedimiento para la preparacion de benzoquinolicinas | |
| TW328083B (en) | New derivatives of β-methoxy acrylic acid, their preparation process and their use as pesticides | |
| ES524524A0 (es) | Procedimiento para la preparacion de un aducto de un diisocianato | |
| DK653788A (da) | 1,4-disubstituerede piperidinyl-forbindelser samt anvendelsen heraf |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |