PE20220372A1 - Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros - Google Patents
Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopterosInfo
- Publication number
- PE20220372A1 PE20220372A1 PE2021002064A PE2021002064A PE20220372A1 PE 20220372 A1 PE20220372 A1 PE 20220372A1 PE 2021002064 A PE2021002064 A PE 2021002064A PE 2021002064 A PE2021002064 A PE 2021002064A PE 20220372 A1 PE20220372 A1 PE 20220372A1
- Authority
- PE
- Peru
- Prior art keywords
- inhibitors
- chimeric proteins
- lepidoptera pests
- domain
- pests
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 4
- 108020001507 fusion proteins Proteins 0.000 title abstract 4
- 241000255777 Lepidoptera Species 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 239000002917 insecticide Substances 0.000 title 1
- 231100000331 toxic Toxicity 0.000 title 1
- 230000002588 toxic effect Effects 0.000 title 1
- 241000607479 Yersinia pestis Species 0.000 abstract 2
- 101150102464 Cry1 gene Proteins 0.000 abstract 1
- 101710151559 Crystal protein Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pest Control & Pesticides (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Cell Biology (AREA)
- Insects & Arthropods (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Manufacturing Of Steel Electrode Plates (AREA)
Abstract
La presente invencion se refiere a una proteina quimerica de SEC ID NO: 4 (TIC1100), a un polinucleotido que la codifica, a una celula hospedadora y a una composicion. Dicha proteina quimerica posee el dominio 1 de Cry1Ah, el dominio 2 de Cry1Ac, el dominio 3 de Cry1Ca y la protoxina de Cry1Ac, siendo miembro de la familia de proteinas cristalinas Cry1. La proteina quimerica de la invencion posee bioactividad contra un amplio espectro de plagas de lepidopteros, siendo efectiva en el control de dichas plagas en cultivos agricolas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462064989P | 2014-10-16 | 2014-10-16 | |
| PCT/US2015/055800 WO2016061391A2 (en) | 2014-10-16 | 2015-10-15 | Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20220372A1 true PE20220372A1 (es) | 2022-03-16 |
Family
ID=54608929
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2021002061A PE20220375A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2021002063A PE20220374A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2021002059A PE20220940A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2021002064A PE20220372A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2017000604A PE20170895A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2021002061A PE20220375A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2021002063A PE20220374A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
| PE2021002059A PE20220940A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017000604A PE20170895A1 (es) | 2014-10-16 | 2015-10-15 | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros |
Country Status (29)
| Country | Link |
|---|---|
| US (8) | US10233217B2 (es) |
| EP (5) | EP3207049B1 (es) |
| JP (1) | JP6626102B2 (es) |
| KR (5) | KR102208980B1 (es) |
| CN (5) | CN112175093B (es) |
| AR (6) | AR103129A1 (es) |
| AU (6) | AU2015332384B2 (es) |
| BR (4) | BR122020004875B1 (es) |
| CA (3) | CA3151123A1 (es) |
| CL (5) | CL2017000895A1 (es) |
| CO (1) | CO2017004807A2 (es) |
| CR (3) | CR20170198A (es) |
| CU (5) | CU24541B1 (es) |
| EA (5) | EA201892762A1 (es) |
| EC (1) | ECSP17029551A (es) |
| ES (1) | ES2864657T3 (es) |
| IL (1) | IL251570B (es) |
| MX (5) | MX388283B (es) |
| MY (1) | MY181627A (es) |
| NI (1) | NI201700044A (es) |
| NZ (3) | NZ768153A (es) |
| PE (5) | PE20220375A1 (es) |
| PH (5) | PH12017500697A1 (es) |
| SG (5) | SG11201702749RA (es) |
| SV (1) | SV2017005422A (es) |
| UA (4) | UA123482C2 (es) |
| UY (3) | UY40226A (es) |
| WO (1) | WO2016061391A2 (es) |
| ZA (6) | ZA201702191B (es) |
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|---|---|---|---|---|
| ES2982696T3 (es) * | 2013-12-09 | 2024-10-17 | BASF Agricultural Solutions Seed US LLC | Gen de la toxina AXMI486 y procedimientos para su uso |
| US10233217B2 (en) | 2014-10-16 | 2019-03-19 | Monsanto Technology Llc | Chimeric insecticidal proteins toxic or inhibitory to Lepidopteran pests |
| CN114736275A (zh) | 2014-10-16 | 2022-07-12 | 先锋国际良种公司 | 具有改进的活性谱的杀昆虫多肽及其用途 |
| US10487123B2 (en) | 2014-10-16 | 2019-11-26 | Monsanto Technology Llc | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests |
| CN107771181A (zh) | 2015-06-16 | 2018-03-06 | 先锋国际良种公司 | 用以防治昆虫有害生物的组合物和方法 |
| WO2017030808A1 (en) | 2015-08-18 | 2017-02-23 | Monsanto Technology Llc | Novel insect inhibitory proteins |
| CU24542B1 (es) | 2015-08-27 | 2021-08-06 | Monsanto Technology Llc | Proteínas inhibidoras de insectos provenientes de paenibacillus popilliae |
| US10572836B2 (en) | 2015-10-15 | 2020-02-25 | International Business Machines Corporation | Automatic time interval metadata determination for business intelligence and predictive analytics |
| US20190185867A1 (en) | 2016-06-16 | 2019-06-20 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| US20210292778A1 (en) | 2016-07-12 | 2021-09-23 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| US11016730B2 (en) | 2016-07-28 | 2021-05-25 | International Business Machines Corporation | Transforming a transactional data set to generate forecasting and prediction insights |
| CN110087471B (zh) * | 2016-10-21 | 2022-08-16 | 先锋国际良种公司 | 来自植物的杀昆虫蛋白及其使用方法 |
| EP3550961A4 (en) | 2016-12-12 | 2020-11-04 | Syngenta Participations AG | ENGINEERED PROTEIN PESTICIDES AND METHODS FOR CONTROLLING PLANT PESTS |
| CN110022676B (zh) * | 2017-01-04 | 2023-07-25 | 先正达参股股份有限公司 | 用于控制植物有害生物的组合物和方法 |
| CR20190367A (es) | 2017-01-12 | 2019-09-25 | Monsanto Technology Llc | Proteínas toxinas pesticidas activas contra insectos lepidópteros |
| US20200165626A1 (en) | 2017-10-13 | 2020-05-28 | Pioneer Hi-Bred International, Inc. | Virus-induced gene silencing technology for insect control in maize |
| CN108148841B (zh) * | 2017-12-14 | 2020-12-29 | 云南大学 | 氨基酸序列在用于使昆虫Dip3蛋白失活中的应用 |
| EP4122947A1 (en) * | 2017-12-19 | 2023-01-25 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides and uses thereof |
| AU2019234566B2 (en) | 2018-03-14 | 2024-09-26 | Hexima Limited | Insecticidal proteins from plants and methods for their use |
| US11820791B2 (en) * | 2018-03-14 | 2023-11-21 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| CN112512305B (zh) * | 2018-07-30 | 2024-02-27 | 孟山都技术公司 | 玉米转基因事件mon 95379及其检测方法和用途 |
| CN109198845A (zh) * | 2018-08-21 | 2019-01-15 | 广州杰赛科技股份有限公司 | 全自主甲面彩绘装置、方法、设备及存储介质 |
| BR112021003797A2 (pt) | 2018-08-29 | 2021-05-25 | Pioneer Hi-Bred International, Inc. | proteínas inseticidas e métodos para seu uso |
| CN113179823B (zh) * | 2020-01-14 | 2025-10-28 | 先正达生物科技(中国)有限公司 | 小地老虎的控制 |
| CN113179822A (zh) * | 2020-01-14 | 2021-07-30 | 先正达生物科技(中国)有限公司 | 棉铃虫的控制 |
| CN111100208A (zh) * | 2020-01-16 | 2020-05-05 | 黑龙江大鹏农业有限公司 | 一种人工合成的抗虫蛋白mCry1Ia2及其制备方法和应用 |
| WO2022125639A1 (en) | 2020-12-08 | 2022-06-16 | Monsanto Technology Llc | Modified plant-associated bacteria and methods of their use |
| EP4262400A4 (en) | 2020-12-21 | 2025-01-08 | Monsanto Technology LLC | NEW INSECT INHIBITORY PROTEINS |
| UY39585A (es) | 2020-12-23 | 2022-07-29 | Monsanto Technology Llc | Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas |
| CN114680126A (zh) * | 2020-12-29 | 2022-07-01 | 先正达生物科技(中国)有限公司 | 夜蛾、草螟和螟蛾有害生物的防治 |
| WO2022146874A1 (en) | 2020-12-31 | 2022-07-07 | Monsanto Technology Llc | Novel insect inhibitory proteins |
| TW202300650A (zh) | 2021-03-26 | 2023-01-01 | 美商旗艦先鋒創新有限責任(Vii)公司 | 真核系統中環狀多核糖核苷酸的產生 |
| TW202305130A (zh) | 2021-03-26 | 2023-02-01 | 美商旗艦先鋒創新有限責任(Vii)公司 | 原核系統中環狀多核糖核苷酸之產生 |
| EP4314277A1 (en) | 2021-03-26 | 2024-02-07 | Flagship Pioneering Innovations VII, LLC | Compositions and methods for producing circular polyribonucleotides |
| AR125862A1 (es) * | 2021-05-21 | 2023-08-23 | Syngenta Crop Protection Ag | Composiciones y métodos para controlar insectos |
| CA3226147A1 (en) | 2021-07-08 | 2023-01-12 | Monsanto Technology Llc | Novel insect inhibitory proteins |
| CN114134171B (zh) * | 2021-10-29 | 2023-09-15 | 隆平生物技术(海南)有限公司 | 一种抑制或杀灭东方黏虫的方法及其应用 |
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| CN114507673A (zh) * | 2022-01-20 | 2022-05-17 | 隆平生物技术(海南)有限公司 | 一种抑制或杀灭小地老虎的方法及应用 |
| US20250230452A1 (en) | 2022-01-20 | 2025-07-17 | Flagship Pioneering Innovations Vii, Llc | Polynucleotides for modifying organisms |
| CN116063431B (zh) * | 2022-09-19 | 2023-11-10 | 隆平生物技术(海南)有限公司 | 一种植物抗虫蛋白质及其应用 |
| CN120476134A (zh) * | 2022-11-04 | 2025-08-12 | 巴西农业研究公司-恩布拉帕 | 截短的嵌合杀虫蛋白 |
| AR132586A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de amalgavirus artificiales |
| WO2024229385A1 (en) | 2023-05-03 | 2024-11-07 | Flagship Pioneering Innovations Vii, Llc | Artificial ghabrivirales satellite rnas |
| AR132589A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de solemoviridae artificiales |
| WO2024229359A2 (en) | 2023-05-03 | 2024-11-07 | Flagship Pioneering Innovations Vii, Llc | Artificial tymovirales satellite rnas |
| AR132591A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de secoviridae artificiales |
| WO2024229403A1 (en) | 2023-05-03 | 2024-11-07 | Flagship Pioneering Innovations Vii, Llc | Endornaviral satellite rna amplification systems for plants |
| AR132587A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de martellivirales artificiales |
| WO2024229395A1 (en) | 2023-05-03 | 2024-11-07 | Flagship Pioneering Innovations Vii, Llc | Partitiviral satellite rna amplification systems for plants |
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