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PE20210288A1 - Anti-cd25 para el agotamiento de celulas tumorales especificas - Google Patents

Anti-cd25 para el agotamiento de celulas tumorales especificas

Info

Publication number
PE20210288A1
PE20210288A1 PE2020001299A PE2020001299A PE20210288A1 PE 20210288 A1 PE20210288 A1 PE 20210288A1 PE 2020001299 A PE2020001299 A PE 2020001299A PE 2020001299 A PE2020001299 A PE 2020001299A PE 20210288 A1 PE20210288 A1 PE 20210288A1
Authority
PE
Peru
Prior art keywords
depletion
tumor cells
specific tumor
antibodies
present disclosure
Prior art date
Application number
PE2020001299A
Other languages
English (en)
Inventor
Anne Goubier
Corzo Beatriz Goyenechea
Josephine Salimu
Kevin Moulder
Pascal Merchiers
Mark Brown
Sergio Quezada
James Geoghegan
Bianka Prinz
Original Assignee
Cancer Research Tech Ltd
Tusk Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1804027.9A external-priority patent/GB201804027D0/en
Priority claimed from PCT/EP2018/056312 external-priority patent/WO2018167104A1/en
Priority claimed from GBGB1804029.5A external-priority patent/GB201804029D0/en
Priority claimed from GBGB1804028.7A external-priority patent/GB201804028D0/en
Application filed by Cancer Research Tech Ltd, Tusk Therapeutics Ltd filed Critical Cancer Research Tech Ltd
Publication of PE20210288A1 publication Critical patent/PE20210288A1/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Abstract

La presente divulgacion proporciona secuencias de anticuerpos encontradas en anticuerpos que se unen a CD25 humana. En particular, la presente divulgacion proporciona secuencias de anticuerpos anti-CD25 humanos, que no bloquean la union de CD25 a IL-2 ni la senalizacion de IL-2. Los anticuerpos y las porciones de union a antigeno de los mismos que incluyen dichas secuencias se pueden usar en composiciones farmaceuticas y metodos de tratamiento, en particular para tratar el cancer
PE2020001299A 2018-03-13 2019-03-13 Anti-cd25 para el agotamiento de celulas tumorales especificas PE20210288A1 (es)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201862642218P 2018-03-13 2018-03-13
US201862642232P 2018-03-13 2018-03-13
US201862642230P 2018-03-13 2018-03-13
US201862642248P 2018-03-13 2018-03-13
US201862642243P 2018-03-13 2018-03-13
GBGB1804027.9A GB201804027D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
PCT/EP2018/056312 WO2018167104A1 (en) 2017-03-17 2018-03-13 Fc-optimized anti-cd25 for tumour specific cell depletion
GBGB1804029.5A GB201804029D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804028.7A GB201804028D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
PCT/EP2019/056249 WO2019175217A1 (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

Publications (1)

Publication Number Publication Date
PE20210288A1 true PE20210288A1 (es) 2021-02-11

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PE2020001299A PE20210288A1 (es) 2018-03-13 2019-03-13 Anti-cd25 para el agotamiento de celulas tumorales especificas
PE2020001292A PE20210287A1 (es) 2018-03-13 2019-03-13 Anti-cd25 para el agotamiento de celulas tumorales especificas
PE2020001320A PE20210289A1 (es) 2018-03-13 2019-03-13 Anti-cd25 para el agotamiento de celulas tumorales especificas

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PE2020001320A PE20210289A1 (es) 2018-03-13 2019-03-13 Anti-cd25 para el agotamiento de celulas tumorales especificas

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US (11) US10745485B2 (es)
EP (8) EP3765503B1 (es)
JP (8) JP7565797B2 (es)
KR (3) KR20200131862A (es)
CN (8) CN112020512B (es)
AU (3) AU2019233581B2 (es)
BR (3) BR112020016499A2 (es)
CA (3) CA3088246A1 (es)
CR (3) CR20200467A (es)
MA (1) MA51993A (es)
PE (3) PE20210288A1 (es)
SG (3) SG11202008784RA (es)
TW (3) TW201940515A (es)
WO (8) WO2019175216A1 (es)

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