PE20200698A1 - Gel que comprende clorhexidina - Google Patents
Gel que comprende clorhexidinaInfo
- Publication number
- PE20200698A1 PE20200698A1 PE2020000181A PE2020000181A PE20200698A1 PE 20200698 A1 PE20200698 A1 PE 20200698A1 PE 2020000181 A PE2020000181 A PE 2020000181A PE 2020000181 A PE2020000181 A PE 2020000181A PE 20200698 A1 PE20200698 A1 PE 20200698A1
- Authority
- PE
- Peru
- Prior art keywords
- same
- chlorhexidine
- composition
- salt
- mixtures
- Prior art date
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003260 chlorhexidine Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 abstract 1
- 229920013820 alkyl cellulose Polymers 0.000 abstract 1
- 229960002152 chlorhexidine acetate Drugs 0.000 abstract 1
- 229960003333 chlorhexidine gluconate Drugs 0.000 abstract 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 abstract 1
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA COMPOSICION DE GEL QUE COMPRENDE: A) DE 0,05% P/P A 1,5% P/P DE CLORHEXIDINA Y/O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LA MISMA EN RELACION CON EL PESO TOTAL DE LA COMPOSICION DE GEL, DONDE DICHA SAL SE SELECCIONA DE GLUCONATO DE CLORHEXIDINA, ACETATO DE CLORHEXIDINA, CLORHIDRATO DE CLORHEXIDINA Y MEZCLAS DE LOS MISMOS; B) DE 0,1% A 1,0% DE ACIDO HIALURONICO EN RELACION CON EL PESO TOTAL DE LA COMPOSICION; C) DE 1,0% A 5,0% DE UNA MATRIZ GELIFICANTE QUE COMPRENDE AGUA Y UN DERIVADO DE CELULOSA, DONDE DICHO DERIVADO DE CELULOSA COMPRENDE CARBOXI (C1-C3) ALQUILCELULOSA Y/O UNA SAL DE LA MISMA, LA CUAL ES CARBOXIMETILCELULOSA; Y D) UN SOLVENTE TAL COMO POLIALQUILENGLICOL, GLICERINA, PROPILENGLICOL Y MEZCLAS DE LOS MISMOS. DICHA COMPOSICION ES UTIL EN LA HIGIENE DE LA CAVIDAD ORAL
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17382547 | 2017-08-04 | ||
| IE20170230A IE87094B1 (en) | 2017-08-04 | 2017-11-02 | Gel comprising chlorhexidine |
| PCT/EP2018/071155 WO2019025599A1 (en) | 2017-08-04 | 2018-08-03 | GEL COMPRISING CHLORHEXIDINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20200698A1 true PE20200698A1 (es) | 2020-06-16 |
Family
ID=63047391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2020000181A PE20200698A1 (es) | 2017-08-04 | 2018-08-03 | Gel que comprende clorhexidina |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3661480A1 (es) |
| CN (1) | CN110996891B (es) |
| BR (1) | BR112020002106B1 (es) |
| CL (1) | CL2020000293A1 (es) |
| CR (1) | CR20200058A (es) |
| IE (1) | IE87094B1 (es) |
| MX (1) | MX2020001363A (es) |
| NI (1) | NI202000007A (es) |
| PE (1) | PE20200698A1 (es) |
| PH (1) | PH12020550032A1 (es) |
| WO (1) | WO2019025599A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022538521A (ja) * | 2019-06-14 | 2022-09-05 | ザ プロクター アンド ギャンブル カンパニー | 洗い流さない口腔ケア組成物 |
| WO2020248239A1 (en) * | 2019-06-14 | 2020-12-17 | The Procter & Gamble Company | Leave-on oral care compositions |
| EP3982917A1 (en) | 2019-06-14 | 2022-04-20 | The Procter & Gamble Company | Leave-on oral care compositions |
| CN114040742A (zh) | 2019-06-14 | 2022-02-11 | 宝洁公司 | 免洗型口腔护理组合物 |
| WO2020248232A1 (en) * | 2019-06-14 | 2020-12-17 | The Procter & Gamble Company | Leave-on oral care compositions |
| CN111494376A (zh) * | 2020-06-15 | 2020-08-07 | 牡丹江医学院 | 一种用于治疗牙龈炎的药物及其制备方法 |
| IT202000029288A1 (it) * | 2020-12-01 | 2022-06-01 | Altergon Sa | Sali di microbiocidi biguanidinici con glicosamminoglicani |
| EP4203910A1 (en) * | 2021-05-26 | 2023-07-05 | Colgate-Palmolive Company | Oral care compositions |
| CN113440441B (zh) * | 2021-07-29 | 2022-09-16 | 山东福瑞达生物股份有限公司 | 一种含精油的口腔抑菌组合物及其制备方法 |
| EP4483889A1 (en) | 2023-06-28 | 2025-01-01 | Igen Biolab Group AG | Postbiotic composition for oral administration for preventing or treating oral dysbiosis |
| GR1010853B (el) * | 2023-11-10 | 2025-01-10 | Ιουλια Τσετη | Συνθεση υαλουρονικου νατριου και σουκραλφατης καταλληλη για χορηγηση στη στοματικη κοιλοτητα |
| CN119033680A (zh) * | 2024-08-28 | 2024-11-29 | 西南医科大学附属口腔医院 | 一种用于口腔黏膜损伤的水凝胶的制备方法及应用 |
| CN120309762B (zh) * | 2025-04-29 | 2026-01-06 | 杭州三言生物科技有限公司 | 一种具有抑菌作用的透明质酸氯己定的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192802A (en) | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
| CH691030A5 (it) | 1995-09-26 | 2001-04-12 | Apr Applied Pharma Res Sa | Formulazioni per uso topico contenenti carragenina ed un sale dell'acido ialuronico. |
| JPH1160505A (ja) | 1997-05-20 | 1999-03-02 | Senju Pharmaceut Co Ltd | 防腐組成物 |
| US6117415A (en) | 1999-06-17 | 2000-09-12 | Alpharx Inc. | Toothpaste comprising bioadhesive submicron emulsion for improved delivery of antibacterial and anticaries agents |
| US8283135B2 (en) * | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| RU2286764C1 (ru) | 2005-06-16 | 2006-11-10 | Георгий Георгиевич Ростиашвили | Средство "гиалудент" пролонгированного действия для лечения воспалительных заболеваний полости рта |
| US8609634B2 (en) | 2007-05-16 | 2013-12-17 | Mcneil-Ppc, Inc. | Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods |
| US20090068122A1 (en) * | 2007-09-06 | 2009-03-12 | Shira Pilch | Dentifrice Compositions for Treating Xerostomia |
| EP2520279A1 (en) * | 2011-05-02 | 2012-11-07 | TERES S.r.l. | Thermoreversible gel pharamaceutical compositions for odontoiatric use |
| CN104474582A (zh) * | 2014-12-17 | 2015-04-01 | 安徽省健源医疗器械设备有限公司 | 一种含透明质酸的止血纱布及其制备方法 |
| EP3171854B1 (en) * | 2015-05-08 | 2020-03-04 | Curasept Ads S.r.L. | Improved mouthwash preparation |
| CN105342939A (zh) * | 2015-12-15 | 2016-02-24 | 山东消博士消毒科技股份有限公司 | 可降低手术切口感染的消毒沐浴液及其制备工艺 |
| CN106540281A (zh) * | 2016-12-08 | 2017-03-29 | 邓丽萍 | B超耦合剂及其制备工艺 |
-
2017
- 2017-11-02 IE IE20170230A patent/IE87094B1/en unknown
-
2018
- 2018-08-03 WO PCT/EP2018/071155 patent/WO2019025599A1/en not_active Ceased
- 2018-08-03 PE PE2020000181A patent/PE20200698A1/es unknown
- 2018-08-03 BR BR112020002106-7A patent/BR112020002106B1/pt active IP Right Grant
- 2018-08-03 CN CN201880052414.5A patent/CN110996891B/zh active Active
- 2018-08-03 MX MX2020001363A patent/MX2020001363A/es unknown
- 2018-08-03 CR CR20200058A patent/CR20200058A/es unknown
- 2018-08-03 EP EP18746958.0A patent/EP3661480A1/en active Pending
-
2020
- 2020-01-21 PH PH12020550032A patent/PH12020550032A1/en unknown
- 2020-01-28 NI NI202000007A patent/NI202000007A/es unknown
- 2020-01-31 CL CL2020000293A patent/CL2020000293A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NI202000007A (es) | 2020-07-31 |
| CL2020000293A1 (es) | 2020-08-14 |
| CN110996891A (zh) | 2020-04-10 |
| BR112020002106B1 (pt) | 2023-04-18 |
| WO2019025599A1 (en) | 2019-02-07 |
| CR20200058A (es) | 2020-03-28 |
| BR112020002106A8 (pt) | 2020-12-01 |
| PH12020550032A1 (en) | 2021-02-15 |
| IE20170230A1 (en) | 2019-02-06 |
| CN110996891B (zh) | 2023-02-28 |
| IE87094B1 (en) | 2020-05-13 |
| MX2020001363A (es) | 2020-03-20 |
| BR112020002106A2 (pt) | 2020-08-04 |
| EP3661480A1 (en) | 2020-06-10 |
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