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PE20180695A1 - Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer - Google Patents

Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer

Info

Publication number
PE20180695A1
PE20180695A1 PE2018000178A PE2018000178A PE20180695A1 PE 20180695 A1 PE20180695 A1 PE 20180695A1 PE 2018000178 A PE2018000178 A PE 2018000178A PE 2018000178 A PE2018000178 A PE 2018000178A PE 20180695 A1 PE20180695 A1 PE 20180695A1
Authority
PE
Peru
Prior art keywords
peptides
cancer
new
types
peptide combinations
Prior art date
Application number
PE2018000178A
Other languages
English (en)
Inventor
Julia Leibold
Phillip Muller
Toni Weinschenk
Jens Fritsche
Harpreet Singh
Andrea Mahr
Oliver Schoor
Valentina Goldfinger
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54200350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20180695(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of PE20180695A1 publication Critical patent/PE20180695A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N5/0602—Vertebrate cells
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G01N33/57575—
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    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
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Abstract

Esta referido a peptidos, proteinas, acidos nucleicos y celulas destinados a la utilizacion en metodos inmunoterapeuticos. Asimismo, a epitopos peptidicos para linfocitos T asociados a tumores, solos o en combinacion con otros peptidos asociados a tumores que, por ejemplo, pueden servir como principios activos farmaceuticos en composiciones vacunales destinadas a estimular respuestas inmunitarias antitumorales, o a estimular ex vivo linfocitos T que despues seran transferidos a los pacientes. Los peptidos unidos a moleculas del complejo mayor de histocompatibilidad (MHC), o los peptidos como tales, tambien pueden ser dianas de anticuerpos, de receptores de linfocitos T solubles, y de otras moleculas de union, siendo util en la inmunoterapia contra el cancer.
PE2018000178A 2015-08-05 2016-08-05 Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer PE20180695A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562201289P 2015-08-05 2015-08-05
GBGB1513921.5A GB201513921D0 (en) 2015-08-05 2015-08-06 Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers

Publications (1)

Publication Number Publication Date
PE20180695A1 true PE20180695A1 (es) 2018-04-23

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PE2023002284A PE20250557A1 (es) 2015-08-05 2016-08-05 Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer
PE2018000178A PE20180695A1 (es) 2015-08-05 2016-08-05 Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer

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PE2023002284A PE20250557A1 (es) 2015-08-05 2016-08-05 Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de prostata y otros tipos de cancer

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US (24) US9908920B2 (es)
EP (4) EP3842446A1 (es)
JP (4) JP6884752B2 (es)
KR (1) KR20180035845A (es)
CN (2) CN114395013A (es)
AR (1) AR105817A1 (es)
AU (8) AU2016303021B2 (es)
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Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2508923A (en) * 2012-12-17 2014-06-18 Bombardier Transp Gmbh Inductive power transfer system having inductive sensing array
HUE057334T2 (hu) * 2013-08-05 2022-05-28 Immatics Biotechnologies Gmbh Új immunterápia többféle tumor, például tüdõrák ellen, az NSCLC-t is beleértve
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AU2021202057A1 (en) 2021-04-29
AU2021202056B2 (en) 2023-04-06
HRP20210709T1 (hr) 2021-11-26
CL2018000324A1 (es) 2018-05-18
LT3331900T (lt) 2021-03-25
US12076381B2 (en) 2024-09-03
PH12018500189A1 (en) 2018-07-30
CN114395013A (zh) 2022-04-26
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US20200397878A1 (en) 2020-12-24
CR20200435A (es) 2020-10-14
EA201890440A1 (ru) 2018-08-31
AU2021202060A1 (en) 2021-04-29
CR20200433A (es) 2020-10-19
PT3331900T (pt) 2021-03-18
US20170326215A1 (en) 2017-11-16
US20210275654A1 (en) 2021-09-09
CA2994771A1 (en) 2017-02-09
CL2021001543A1 (es) 2022-01-21
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US20190374626A1 (en) 2019-12-12
RS61713B1 (sr) 2021-05-31
EP3854801A3 (en) 2021-09-29
MA53680A (fr) 2021-09-29
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AU2021202059A1 (en) 2021-04-29
PE20250557A1 (es) 2025-02-24
US10799569B2 (en) 2020-10-13
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US20180127473A1 (en) 2018-05-10
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US20220143164A1 (en) 2022-05-12
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CR20200432A (es) 2020-10-19
PL3331900T3 (pl) 2021-08-09
US9993539B2 (en) 2018-06-12
BR112018001687A2 (pt) 2018-09-18
US10376568B2 (en) 2019-08-13
JP7142957B2 (ja) 2022-09-28
HUE053657T2 (hu) 2021-07-28
AU2021202058B2 (en) 2023-04-13
US20190275131A1 (en) 2019-09-12
MA53452A (fr) 2021-06-30
US9908920B2 (en) 2018-03-06
AU2021202060B2 (en) 2023-06-15
MX2021015933A (es) 2022-02-03
US11786584B2 (en) 2023-10-17
CR20200434A (es) 2020-10-19
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