[go: up one dir, main page]

PE20180577A1 - USO DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 PARA CARACTERIZAR LA SEVERIDAD DE INFECCIONES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICIAL Y METAPNEUMOVIRUS HUMANO - Google Patents

USO DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 PARA CARACTERIZAR LA SEVERIDAD DE INFECCIONES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICIAL Y METAPNEUMOVIRUS HUMANO

Info

Publication number
PE20180577A1
PE20180577A1 PE2018000146A PE2018000146A PE20180577A1 PE 20180577 A1 PE20180577 A1 PE 20180577A1 PE 2018000146 A PE2018000146 A PE 2018000146A PE 2018000146 A PE2018000146 A PE 2018000146A PE 20180577 A1 PE20180577 A1 PE 20180577A1
Authority
PE
Peru
Prior art keywords
respiratory
molecular markers
severity
characterize
human metapneumovirus
Prior art date
Application number
PE2018000146A
Other languages
English (en)
Inventor
Parra Alexis Mikes Kalergis
Ramirez Susan Marcela Bueno
Navarrete Jose Pablo Bertrand
Remolcoi Margarita Kam-Lem Lay
Original Assignee
Univ Pontificia Catolica Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pontificia Catolica Chile filed Critical Univ Pontificia Catolica Chile
Publication of PE20180577A1 publication Critical patent/PE20180577A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5403—IL-3
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5434—IL-12
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE REFIERE A LA DETECCION DE ENFERMEDADES RESPIRATORIAS MEDIANTE EL USO DE MARCADORES MOLECULARES COMO HERRAMIENTA PRONOSTICO DE LA EVOLUCION DE CUADROS DE INFECCION RESPIRATORIA, EN CONCRETO DURANTE EL DIAGNOSTICO DIFERENCIAL DE INFECCIONES RESPIRATORIAS CAUSADAS POR EL VIRUS RESPIRATORIO SINCICIAL Y EL METAPNEUMOVIRUS HUMANO, DONDE SE ESTABLECERA EL PATRON DE EXPRESION DE LOS MARCADORES DE SEVERIDAD DE IL-3, IL-33 E IL-12p40. DICHOS PATRONES DE EXPRESION DE LOS MARCADORES MOLECULARES PUEDEN DETERMINARSE EN MUESTRAS BIOLOGICAS MEDIANTE ENSAYOS DE ELISA, CITOMETRIA DE FLUJO O PCR EN TIEMPO REAL. LA CONFIRMACION DEL AGENTE ETIOLOGICO DE LA INFECCION EN COMBINACION CON LA DETERMINACION DEL PATRON DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 INDICARAN UN PRONOSTICO DE SEVERIDAD DE LA ENFERMEDAD
PE2018000146A 2015-07-31 2016-07-25 USO DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 PARA CARACTERIZAR LA SEVERIDAD DE INFECCIONES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICIAL Y METAPNEUMOVIRUS HUMANO PE20180577A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2015002153A CL2015002153A1 (es) 2015-07-31 2015-07-31 Uso de los marcadores moleculares il-3,il33 e il-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humano

Publications (1)

Publication Number Publication Date
PE20180577A1 true PE20180577A1 (es) 2018-04-04

Family

ID=56081023

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2018000146A PE20180577A1 (es) 2015-07-31 2016-07-25 USO DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 PARA CARACTERIZAR LA SEVERIDAD DE INFECCIONES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICIAL Y METAPNEUMOVIRUS HUMANO

Country Status (17)

Country Link
US (1) US11085080B2 (es)
EP (1) EP3329019B1 (es)
KR (1) KR102621463B1 (es)
CN (1) CN108368556B (es)
AR (1) AR105542A1 (es)
BR (1) BR112018002140B1 (es)
CA (1) CA2994252A1 (es)
CL (1) CL2015002153A1 (es)
CO (1) CO2018001917A2 (es)
ES (1) ES2783859T3 (es)
MX (1) MX2018001373A (es)
PE (1) PE20180577A1 (es)
PT (1) PT3329019T (es)
RU (1) RU2707549C2 (es)
UY (1) UY36819A (es)
WO (1) WO2017021814A1 (es)
ZA (1) ZA201800940B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7231326B2 (ja) 2014-11-10 2023-03-01 ジェネンテック， インコーポレイテッド Ｉｌ－３３媒介性障害のための治療及び診断方法
US10093730B2 (en) 2014-11-10 2018-10-09 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
EP4118114A1 (en) 2020-03-13 2023-01-18 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
JP6960642B2 (ja) * 2020-04-16 2021-11-05 国立研究開発法人国立国際医療研究センター 呼吸器感染症の重症化の予測を補助する方法、バイオマーカーの測定値をモニタリングする方法、これらの方法に用いられる試薬キット、呼吸器感染症の重症化の予測を補助する装置およびコンピュータプログラム

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010531890A (ja) * 2007-06-26 2010-09-30 メディミューン，エルエルシー Ｒｓｖ感染症及び関連する症状の治療方法
KR101286463B1 (ko) * 2011-01-28 2013-07-16 환인제약 주식회사 천궁 추출물을 함유하는 호흡기 질환의 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
WO2017021814A1 (en) 2017-02-09
EP3329019A4 (en) 2018-06-06
CN108368556A (zh) 2018-08-03
RU2018104707A (ru) 2019-08-28
CN108368556B (zh) 2021-06-22
CO2018001917A2 (es) 2018-05-10
RU2018104707A3 (es) 2019-08-28
EP3329019B1 (en) 2020-01-01
AR105542A1 (es) 2017-10-11
MX2018001373A (es) 2018-06-15
UY36819A (es) 2017-01-31
BR112018002140B1 (pt) 2024-01-23
PT3329019T (pt) 2020-04-08
KR102621463B1 (ko) 2024-01-04
US11085080B2 (en) 2021-08-10
US20180327843A1 (en) 2018-11-15
EP3329019A1 (en) 2018-06-06
CA2994252A1 (en) 2017-02-09
CL2015002153A1 (es) 2016-01-29
BR112018002140A2 (pt) 2018-09-11
KR20180028525A (ko) 2018-03-16
RU2707549C2 (ru) 2019-11-27
ES2783859T3 (es) 2020-09-18
ZA201800940B (en) 2019-07-31

Similar Documents

Publication Publication Date Title
CL2016002679A1 (es) Métodos para mejorar o acelerar la recuperación física después la cirugía por fractura de cadera.
SV2018005610A (es) Derivados de oxopiridina sustituidos
MX386750B (es) MARCADORES DE METILACIÓN Y DE miARN PARA LA DETECCIÓN DE CÁNCER.
MX390764B (es) Ensayos dispersables en agua
MX2017008421A (es) Métodos terapéuticos, diagnósticos y pronósticos para el cáncer de vejiga.
MX2021008376A (es) Cultivo, produccion, procesamiento y uso de cannabis de especialidad.
EP4556576A3 (en) Methods to diagnose and treat acute respiratory infections
BR112015022934A8 (pt) esteróides neuroativos, composições e usos destes
MX2017002361A (es) Mono-, di-, o polisacarido usado como inhibidor de metal en la preparacion del agente enfocado funcionalizado con quelato galio 68 (68ga).
BR112016017986A2 (pt) anticorpos isolados, ácido nucleico isolado, célula hospedeira, métodos de produção de um anticorpo, de tratamento do câncer, de tratamento de uma doença e de detecção de jagged1 humana em uma amostra biológica, imunoconjugado, formulação farmacêutica e uso do anticorpo
MX2020011100A (es) Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar.
IT201700072994A1 (it) Sistema plurisensoriale adattato per la prevenzione di malattie professionali nell’ambiente di lavoro, e metodo per l’uso del sistema
UY36187A (es) Anticuerpos antagonistas de interferón alfa y omega
MX2017006242A (es) Determinacion de niveles de glicosaminoglicanos mediante espectrometria de masas.
MX2023006415A (es) Anticuerpos, usos y metodos.
BR112018070188A2 (pt) uso de caulim como opacificante
MX375145B (es) Matrices detectables, sistemas para el diagnóstico y sus métodos de preparación y uso.
PE20180577A1 (es) USO DE LOS MARCADORES MOLECULARES IL-3, IL-33 E IL-12p40 PARA CARACTERIZAR LA SEVERIDAD DE INFECCIONES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICIAL Y METAPNEUMOVIRUS HUMANO
MX395376B (es) Dispositivo para la deteccion de proteinas mal plegadas y metodos de uso del mismo.
BR112017010420A2 (pt) métodos de controle de índice de fusão de poliolefina enquanto aumentando a produtividade do catalisador
CL2015003563A1 (es) Marcador para trastornos de la esfingomielinasa ácida y sus usos.
MA40636A (fr) Procédés pour détecter le cancer de la prostate
MX383563B (es) Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico.
MX2016015531A (es) Ensayo de inflamacion oral.
BR112015024877A2 (pt) vacinas que compreendem polipeptídeos de leishmania para o tratamento e diagnóstico de leishmaniose