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PE20150633A1 - Composicion para el tratamiento de la hiperlipidemia que comprende un derivado de oxintomodulina - Google Patents

Composicion para el tratamiento de la hiperlipidemia que comprende un derivado de oxintomodulina

Info

Publication number
PE20150633A1
PE20150633A1 PE2015000094A PE2015000094A PE20150633A1 PE 20150633 A1 PE20150633 A1 PE 20150633A1 PE 2015000094 A PE2015000094 A PE 2015000094A PE 2015000094 A PE2015000094 A PE 2015000094A PE 20150633 A1 PE20150633 A1 PE 20150633A1
Authority
PE
Peru
Prior art keywords
derivative
oxynomodulin
treatment
composition
hyperlipidemia
Prior art date
Application number
PE2015000094A
Other languages
English (en)
Inventor
Sung Youb Jung
Jin-Sun Kim
Myung Hyun Jang
Sang Hyun Lee
In Young Choi
Se Chang Kwon
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49997578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20150633(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of PE20150633A1 publication Critical patent/PE20150633A1/es

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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

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Abstract

La invencion describe una composicion para prevenir o tratar la hiperlipidemia, el higado graso o la arterioesclerosis que comprende un derivado de oxintomodulina como ingrediente activo. El derivado de oxintomodulina tiene una gran capacidad para activar el receptor de GLP-1 y el receptor de glucagon en comparacion con la oxintomodulina nativa y tiene los efectos de reducir los niveles de colesterol en sangre, de colesterol de baja densidad y de trigliceridos que se elevan por las dietas con alto contenido en grasas y de aumentar los niveles de colesterol de alta densidad y la relacion entre el colesterol de alta y baja densidad. Por lo tanto, el derivado de oxintomodulina puede ser eficazmente usado para el tratamiento de la hiperlipidemia y de las enfermedades relacionadas
PE2015000094A 2012-07-25 2013-07-25 Composicion para el tratamiento de la hiperlipidemia que comprende un derivado de oxintomodulina PE20150633A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020120081475A KR101968344B1 (ko) 2012-07-25 2012-07-25 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물

Publications (1)

Publication Number Publication Date
PE20150633A1 true PE20150633A1 (es) 2015-05-06

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ID=49997578

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PE2015000094A PE20150633A1 (es) 2012-07-25 2013-07-25 Composicion para el tratamiento de la hiperlipidemia que comprende un derivado de oxintomodulina

Country Status (24)

Country Link
US (3) US20150182593A1 (es)
EP (3) EP3384925B1 (es)
JP (4) JP2015524427A (es)
KR (1) KR101968344B1 (es)
CN (2) CN104507492B (es)
AR (1) AR091903A1 (es)
AU (2) AU2013293714B2 (es)
BR (2) BR122022025353B1 (es)
CA (2) CA3121985A1 (es)
CL (4) CL2015000177A1 (es)
DK (1) DK3384925T3 (es)
ES (2) ES2842881T3 (es)
IL (2) IL236913B (es)
MX (2) MX360024B (es)
MY (2) MY171493A (es)
NZ (2) NZ705384A (es)
PE (1) PE20150633A1 (es)
PH (2) PH12015500158B1 (es)
RU (2) RU2642267C2 (es)
SG (2) SG11201500519UA (es)
TW (3) TWI661837B (es)
UA (2) UA128812C2 (es)
WO (1) WO2014017843A1 (es)
ZA (2) ZA201501238B (es)

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DK3878859T5 (da) 2011-06-10 2024-06-10 Hanmi Science Co Ltd Hidtil ukendte oxyntomodulinderivater og farmaceutisk præparat til behandling af fedme omfattende disse
SI2721062T1 (sl) 2011-06-17 2019-03-29 Hanmi Science Co., Ltd. Konjugat, obsegajoč oksintomodulinski in imunoglobinski fragment, in uporaba le-tega
KR20130049671A (ko) 2011-11-04 2013-05-14 한미사이언스 주식회사 생리활성 폴리펩타이드 결합체 제조 방법
AR090281A1 (es) 2012-03-08 2014-10-29 Hanmi Science Co Ltd Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo
KR101968344B1 (ko) * 2012-07-25 2019-04-12 한미약품 주식회사 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
KR101993393B1 (ko) * 2012-11-06 2019-10-01 한미약품 주식회사 옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
MY168536A (en) 2012-11-06 2018-11-12 Hanmi Pharm Ind Co Ltd Liquid formulation of protein conjugate comprising an oxyntomodulin derivative covalently linked to a non-peptidyl polymer to an immunoglobulin fc region
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EP3080150B1 (en) 2013-12-13 2018-08-01 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
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