PE20121473A1 - Uso de 4-[etil(dimetil)amonio]butanoato en el tratamiento de enfermedades cardiovasculares - Google Patents
Uso de 4-[etil(dimetil)amonio]butanoato en el tratamiento de enfermedades cardiovascularesInfo
- Publication number
- PE20121473A1 PE20121473A1 PE2012000523A PE2012000523A PE20121473A1 PE 20121473 A1 PE20121473 A1 PE 20121473A1 PE 2012000523 A PE2012000523 A PE 2012000523A PE 2012000523 A PE2012000523 A PE 2012000523A PE 20121473 A1 PE20121473 A1 PE 20121473A1
- Authority
- PE
- Peru
- Prior art keywords
- ethyl
- dimethyl
- butanoate
- ammonium
- treatment
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 1
- RDHPKYGYEGBMSE-UHFFFAOYSA-N bromoethane Chemical compound CCBr RDHPKYGYEGBMSE-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UN PROCESO DE PREPARACION DEL COMPUESTO 4-[ETIL(DIMETIL)AMONIO]BUTANOATO, QUE COMPRENDE: (A) ANADIR BROMURO DE ETILO A 4-(DIMETILAMONIO)BUTANOATO EN ACETONA PARA LA OBTENCION DEL BROMURO DE N-ETIL-4-METOXI-N,N-DIMETIL-4-OXO-1-BUTANAMINIO Y (B) TRATAR BROMURO DE N-ETIL-4-METOXI-N,N-DIMETIL-4-OXO-1-BUTANAMINIO CON SOLUCION DE HIDROXIDO POTASICO EN ETANOL. DICHO COMPUESTO TIENE UN EFECTO CARDIOPROTECTOR SIENDO UTIL PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LVP-09-181A LV14345B (lv) | 2009-10-22 | 2009-10-22 | 4-[Etil(dimetil)amonija]butanoāts un tā izmantošana kardiovaskulāro slimību ārstēšanai |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20121473A1 true PE20121473A1 (es) | 2012-11-18 |
Family
ID=43530044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2012000523A PE20121473A1 (es) | 2009-10-22 | 2010-10-22 | Uso de 4-[etil(dimetil)amonio]butanoato en el tratamiento de enfermedades cardiovasculares |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US9278907B2 (es) |
| EP (1) | EP2491005B1 (es) |
| JP (1) | JP5552169B2 (es) |
| KR (1) | KR101355417B1 (es) |
| CN (1) | CN102666476B (es) |
| AR (1) | AR081514A1 (es) |
| AU (1) | AU2010309756B2 (es) |
| BR (1) | BR112012009162B8 (es) |
| CA (1) | CA2781499C (es) |
| CL (1) | CL2012001010A1 (es) |
| CO (1) | CO6531459A2 (es) |
| CU (1) | CU20120065A7 (es) |
| DK (1) | DK2491005T3 (es) |
| EA (1) | EA020303B1 (es) |
| ES (1) | ES2508117T3 (es) |
| GE (1) | GEP20146123B (es) |
| HR (1) | HRP20140964T1 (es) |
| IL (1) | IL219217A0 (es) |
| LV (1) | LV14345B (es) |
| ME (1) | ME01917B (es) |
| MX (1) | MX2012004630A (es) |
| NZ (1) | NZ599521A (es) |
| PE (1) | PE20121473A1 (es) |
| PL (1) | PL2491005T3 (es) |
| PT (1) | PT2491005E (es) |
| RS (1) | RS53620B1 (es) |
| SI (1) | SI2491005T1 (es) |
| SM (1) | SMT201400176B (es) |
| TN (1) | TN2012000174A1 (es) |
| UA (1) | UA107201C2 (es) |
| WO (1) | WO2011048201A1 (es) |
| ZA (1) | ZA201202916B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8565150B2 (en) * | 2009-03-11 | 2013-10-22 | At&T Mobility Ii Llc | Architectural model for LTE (long term evolution) EPC (evolved packet core) deployment |
| RS55092B1 (sr) * | 2011-04-27 | 2016-12-30 | Grindeks Jsc | Upotreba 3-karboksi-n-etil-n,n-dimetilpropan-1-aminijum soli u lečenju kardiovaskularne bolesti |
| DE102012109911A1 (de) | 2011-10-19 | 2013-04-25 | Electronics And Telecommunications Research Institute | Energy harvesting device using electromagnetic interference signal and sensor system including the same |
| JO3117B1 (ar) * | 2012-12-20 | 2017-09-20 | Grindeks Jsc | استعمال 3- كربوكسي- ن-إيثيل- ن، ن- ثاني ميثيل بروبان-1– أمينيوم أو ملح منه مقبول صيدلانياً في معالجة تصلب الشرايين |
| JO3333B1 (ar) | 2013-09-26 | 2019-03-13 | Grindeks Jsc | استعمال 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium أو ملح مقبول دوائيا منه للوقاية من السكري وعلاجه |
| CN107879944B (zh) * | 2017-10-30 | 2020-05-22 | 杭州海尔希畜牧科技有限公司 | 一种制备丁基甜菜碱的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1238868A (es) | 1967-08-08 | 1971-07-14 | ||
| SU997646A1 (ru) | 1978-11-27 | 1983-02-23 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Кормова добавка |
| IT1210935B (it) | 1981-09-17 | 1989-09-29 | Inst Orch Sinteza Akademi Nauk | Composizione farmaceutica per il trattamento di malattie cardiovascolari. |
| IT1190280B (it) * | 1986-04-24 | 1988-02-16 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di gamma-butirrobetaina |
| US4933103A (en) * | 1987-03-23 | 1990-06-12 | Kao Corporation | Bleaching composition |
| SU1680693A1 (ru) * | 1987-03-25 | 1991-09-30 | Институт Органического Синтеза Ан Латвсср | Этил-3-(2,2-диметил-2-этилгидразиний)пропионат иодистый, про вл ющий антиаритмическую активность |
| JPH0291049A (ja) * | 1988-09-21 | 1990-03-30 | Lonza Ag | ｒ―ブチロベタインの製造方法 |
| JP3119430B2 (ja) * | 1995-07-25 | 2000-12-18 | 大鵬薬品工業株式会社 | 水酸基ラジカル消去剤 |
| LV11728B (en) | 1995-08-21 | 1997-08-20 | Kalvins Ivars | Pharmaceutical composition |
| US5973026A (en) | 1998-02-02 | 1999-10-26 | Xerox Corporation | Ink jet inks |
| JP2000239239A (ja) * | 1999-02-22 | 2000-09-05 | Kankyo Meneki Gijutsu Kenkyusho:Kk | クロルメコート類縁化合物のハプテン化合物、抗体及び測定方法 |
| CA2508094A1 (en) | 2005-05-20 | 2006-11-20 | Vivier Canada Inc. | Composition for accelerating collagen synthesis |
| US7863274B2 (en) | 2005-07-29 | 2011-01-04 | Concert Pharmaceuticals Inc. | Deuterium enriched analogues of tadalafil as PDE5 inhibitors |
| LV13705B (en) | 2006-11-06 | 2008-07-20 | Ivars Kalvins | Process for producing high purity intermolecular salt of 3-carboxy-n,n,n-trimethyl-propane-1-amine hydroxide |
| JP4761265B2 (ja) | 2007-10-17 | 2011-08-31 | 学校法人甲南学園 | 核酸合成を促進する化合物を含む組成物およびその利用、並びに当該化合物の製造方法 |
| CN101538214A (zh) * | 2009-04-24 | 2009-09-23 | 潍坊祥维斯化学品有限公司 | 生产γ-丁基甜菜碱及其盐酸盐的方法 |
| EP2702037A1 (en) * | 2011-04-27 | 2014-03-05 | Grindeks, A Joint Stock Company | 4-[(haloalkyl)(dimethyl)ammonio]butanoates and use thereof in the treatment of cardiovascular disease |
-
2009
- 2009-10-22 LV LVP-09-181A patent/LV14345B/lv unknown
-
2010
- 2010-10-22 DK DK10773886.6T patent/DK2491005T3/da active
- 2010-10-22 KR KR1020127010343A patent/KR101355417B1/ko active Active
- 2010-10-22 CA CA2781499A patent/CA2781499C/en active Active
- 2010-10-22 BR BR112012009162A patent/BR112012009162B8/pt active IP Right Grant
- 2010-10-22 UA UAA201204970A patent/UA107201C2/ru unknown
- 2010-10-22 GE GEAP201012677A patent/GEP20146123B/en unknown
- 2010-10-22 AU AU2010309756A patent/AU2010309756B2/en active Active
- 2010-10-22 RS RS20140547A patent/RS53620B1/sr unknown
- 2010-10-22 WO PCT/EP2010/065924 patent/WO2011048201A1/en not_active Ceased
- 2010-10-22 PT PT107738866T patent/PT2491005E/pt unknown
- 2010-10-22 HR HRP20140964AT patent/HRP20140964T1/hr unknown
- 2010-10-22 JP JP2012534709A patent/JP5552169B2/ja active Active
- 2010-10-22 EP EP10773886.6A patent/EP2491005B1/en active Active
- 2010-10-22 ES ES10773886.6T patent/ES2508117T3/es active Active
- 2010-10-22 EA EA201200514A patent/EA020303B1/ru unknown
- 2010-10-22 PL PL10773886T patent/PL2491005T3/pl unknown
- 2010-10-22 AR ARP100103859A patent/AR081514A1/es active IP Right Grant
- 2010-10-22 NZ NZ599521A patent/NZ599521A/xx unknown
- 2010-10-22 PE PE2012000523A patent/PE20121473A1/es active IP Right Grant
- 2010-10-22 US US13/503,144 patent/US9278907B2/en active Active
- 2010-10-22 CN CN201080047660.5A patent/CN102666476B/zh active Active
- 2010-10-22 SI SI201030752T patent/SI2491005T1/sl unknown
- 2010-10-22 MX MX2012004630A patent/MX2012004630A/es active IP Right Grant
- 2010-10-22 ME MEP-2014-131A patent/ME01917B/me unknown
-
2012
- 2012-04-16 IL IL219217A patent/IL219217A0/en active IP Right Grant
- 2012-04-16 TN TNP2012000174A patent/TN2012000174A1/en unknown
- 2012-04-20 CL CL2012001010A patent/CL2012001010A1/es unknown
- 2012-04-20 CO CO12065428A patent/CO6531459A2/es unknown
- 2012-04-20 ZA ZA2012/02916A patent/ZA201202916B/en unknown
- 2012-04-23 CU CUP2012000065A patent/CU20120065A7/es active IP Right Grant
-
2014
- 2014-11-21 SM SM201400176T patent/SMT201400176B/xx unknown
-
2016
- 2016-01-27 US US15/007,543 patent/US9573882B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015001101A2 (pt) | formas cristalinas de um inibidor de prolil hidroxilase | |
| BR112013020767A2 (pt) | composições compreendendo ácido peróxi alfa-cetocarboxílico e métodos para a produção e o uso do mesmo | |
| ECSP13012384A (es) | Composición acuosa que contiene bromhexina | |
| BR112013031422A2 (pt) | métodos para converter material lignocelulósico em produtos úteis | |
| CY1118601T1 (el) | Αλκυλαμινο-υποκατεστημενες δικυανοπυριδινες και προφαρμακα τυπου εστερα αμινοξεος αυτων | |
| BR112013031307A2 (pt) | métodos para tratamento de material lignocelulósico | |
| GT201400147A (es) | Pirimidinas y triazinas fusionadas sustituidas y su uso | |
| CL2011000558A1 (es) | Formas cristalinas de un compuesto derivado de 2-tiazolil-4-quinolinil-oxi; sal de sodio del compuesto, composicion farmaceutica que comprende la sal de sodio, util para tratar una infeccion por el virus de la hepatitis c. | |
| AR086237A1 (es) | FORMULACION PARA ANTICUERPO ANTI-a4b7 | |
| BR112013032717A2 (pt) | coagonistas do receptor de glucagon/glp-1 | |
| CL2016000882A1 (es) | Composiciones de arni contra el componente c5 del complemento y métodos para su uso (divisional de sol. n°2710-15). | |
| MX2016002571A (es) | Regulador de ph de transduccion. | |
| CR11746A (es) | Derivados de acido ciclopentanocarboxilico condensados sustituidos con acilamino y su uso como productos farmaceuticos | |
| ECSP10010295A (es) | Formulacion de anticuerpo | |
| EA201071320A1 (ru) | Активаторы глюкокиназы | |
| MX375872B (es) | Procedimiento de preparacion de 5-fluoro-1h-pirazolopiridinas sustituidas. | |
| BR112015029254A2 (pt) | composição detergente de baixo ph compreendendo tensoativos não iônicos | |
| BR112013031493A2 (pt) | composto, composição farmacêutica, uso de um composto, combinação de um composto, dispositivo e processo de preparação de um composto. | |
| UA113620C2 (xx) | Композиція, що містить аморфну (5-фтор-2-метил-3-хінолін-2-ілметиліндол-1-іл)оцтову кислоту | |
| PE20121473A1 (es) | Uso de 4-[etil(dimetil)amonio]butanoato en el tratamiento de enfermedades cardiovasculares | |
| BR112013020841B8 (pt) | Processo para preparar produtos que compreendem ativos estabilizados e composições que compreendem os mesmos | |
| CO6590210A1 (es) | Complejo obtenido a partir de mezclas de ácido hialurónico o una sal del mismo y sulfato de condroitina | |
| PE20141584A1 (es) | Uso de un inhibidor de aromatasa para el tratamiento del hipogonadismo y enfermedades relacionadas | |
| UY32408A (es) | Macrolido anti-inflamatorio | |
| AR091888A1 (es) | Compuestos de urea y su uso como inhibidores de enzimas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |