PE20110412A1 - Formulacion farmaceutica de eprosartan - Google Patents
Formulacion farmaceutica de eprosartanInfo
- Publication number
- PE20110412A1 PE20110412A1 PE2011000022A PE2011000022A PE20110412A1 PE 20110412 A1 PE20110412 A1 PE 20110412A1 PE 2011000022 A PE2011000022 A PE 2011000022A PE 2011000022 A PE2011000022 A PE 2011000022A PE 20110412 A1 PE20110412 A1 PE 20110412A1
- Authority
- PE
- Peru
- Prior art keywords
- pharmaceutical formulation
- eprosartan
- hydrochlorothiazide
- diuretic
- hypertension
- Prior art date
Links
- 239000002080 C09CA02 - Eprosartan Substances 0.000 title abstract 2
- OROAFUQRIXKEMV-LDADJPATSA-N eprosartan Chemical compound C=1C=C(C(O)=O)C=CC=1CN1C(CCCC)=NC=C1\C=C(C(O)=O)/CC1=CC=CS1 OROAFUQRIXKEMV-LDADJPATSA-N 0.000 title abstract 2
- 229960004563 eprosartan Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- GUBGYTABKSRVRQ-UHFFFAOYSA-N 2-(hydroxymethyl)-6-[4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol Chemical compound OCC1OC(OC2C(O)C(O)C(O)OC2CO)C(O)C(O)C1O GUBGYTABKSRVRQ-UHFFFAOYSA-N 0.000 abstract 1
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 229960002003 hydrochlorothiazide Drugs 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA FORMULACION FARMACEUTICA QUE CONTIENE: A) EPROSARTAN ACIDO EN UNA CANTIDAD DE 410MG A 490MG; B) MONOHIDRATO DE ALFA LACTOSA 200M; C) CELULOSA MICROCRISTALINA SILICIFICADA; D) ALMIDON; E) N-VINIL-2-PIRROLIDONA ENTRECRUZADA; Y OPCIONALMENTE F) UN DIURETICO TAL COMO HIDROCLOROTIAZIDA. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE HIPERTENSION, FALLA CARDIACA CONGESTIVA, FALLA RENAL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08160211 | 2008-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20110412A1 true PE20110412A1 (es) | 2011-07-04 |
Family
ID=39731507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011000022A PE20110412A1 (es) | 2008-07-11 | 2009-07-09 | Formulacion farmaceutica de eprosartan |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20100010062A1 (es) |
| EP (1) | EP2317987B1 (es) |
| JP (1) | JP2011527314A (es) |
| KR (1) | KR20110031226A (es) |
| CN (1) | CN102088961A (es) |
| AR (1) | AR072477A1 (es) |
| AU (1) | AU2009268044A1 (es) |
| BR (1) | BRPI0915455A2 (es) |
| CA (1) | CA2730008A1 (es) |
| CO (1) | CO6331424A2 (es) |
| DO (1) | DOP2011000011A (es) |
| EA (1) | EA201170182A1 (es) |
| EC (1) | ECSP10010701A (es) |
| IL (1) | IL210001A0 (es) |
| MX (1) | MX2011000349A (es) |
| NZ (1) | NZ589904A (es) |
| PE (1) | PE20110412A1 (es) |
| TW (1) | TW201006826A (es) |
| UA (1) | UA100434C2 (es) |
| WO (1) | WO2010003996A1 (es) |
| ZA (1) | ZA201100223B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5910311B2 (ja) * | 2012-05-23 | 2016-04-27 | ニプロ株式会社 | 医薬錠剤およびその製造方法 |
| CN102755322B (zh) * | 2012-07-24 | 2013-12-11 | 兆科药业(广州)有限公司 | 一种乐卡地平和阿托伐他汀复方制剂 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE190051T1 (de) * | 1989-06-14 | 2000-03-15 | Smithkline Beecham Corp | Imidazoalkensäure |
| US5656650A (en) * | 1990-12-14 | 1997-08-12 | Smithkline Beecham Corp. | Angiotensin II receptor blocking compositions |
| PL340587A1 (en) * | 1997-11-17 | 2001-02-12 | Smithkline Beecham Corp | Oral preparations of high therapeutic substance content with instantaneous or modifiable release of such substance and methods of obtaining them |
| US6350470B1 (en) * | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
| HUP0103000A3 (en) * | 1998-07-20 | 2002-08-28 | Smithkline Beecham Corp | Bioenhanced formulations comprising eprosartan in oral solid dosage form and process for their preparation |
| EP1694305B1 (en) * | 2003-12-01 | 2019-10-16 | Recordati Ireland Limited | Pharmaceutical compositions comprising lercanidipine |
| WO2005084666A1 (en) * | 2004-03-02 | 2005-09-15 | Abeille Pharmaceuticals, Inc. | Co-formulations of kits of bioactive agents |
| FR2882260A1 (fr) * | 2005-02-21 | 2006-08-25 | Flamel Technologies Sa | Forme pharmaceutique orale multimicroparticulaire a liberation modifiee d'antagonistes des recepteurs de l'angiotensine ii |
| FR2886150B1 (fr) * | 2005-05-24 | 2007-08-24 | Flamel Technologies Sa | Forme pharmaceutique orale a base d'au moins un principe actif dont la solubilite varie en fonction des conditions de ph gastrique |
| CA2628955A1 (en) * | 2005-11-07 | 2007-05-18 | Edward S. Wilson | Compositions of stabilized ramipril in combination with another active agent |
-
2009
- 2009-07-07 AR ARP090102539A patent/AR072477A1/es not_active Application Discontinuation
- 2009-07-08 TW TW098123060A patent/TW201006826A/zh unknown
- 2009-07-09 MX MX2011000349A patent/MX2011000349A/es active IP Right Grant
- 2009-07-09 EP EP09780358.9A patent/EP2317987B1/en active Active
- 2009-07-09 CN CN200980127192XA patent/CN102088961A/zh active Pending
- 2009-07-09 BR BRPI0915455A patent/BRPI0915455A2/pt not_active IP Right Cessation
- 2009-07-09 KR KR1020117003089A patent/KR20110031226A/ko not_active Withdrawn
- 2009-07-09 EA EA201170182A patent/EA201170182A1/ru unknown
- 2009-07-09 PE PE2011000022A patent/PE20110412A1/es not_active Application Discontinuation
- 2009-07-09 CA CA2730008A patent/CA2730008A1/en not_active Abandoned
- 2009-07-09 US US12/500,425 patent/US20100010062A1/en not_active Abandoned
- 2009-07-09 JP JP2011517158A patent/JP2011527314A/ja active Pending
- 2009-07-09 UA UAA201101523A patent/UA100434C2/ru unknown
- 2009-07-09 NZ NZ589904A patent/NZ589904A/xx not_active IP Right Cessation
- 2009-07-09 WO PCT/EP2009/058724 patent/WO2010003996A1/en not_active Ceased
- 2009-07-09 AU AU2009268044A patent/AU2009268044A1/en not_active Abandoned
-
2010
- 2010-12-15 IL IL210001A patent/IL210001A0/en unknown
- 2010-12-21 EC EC2010010701A patent/ECSP10010701A/es unknown
-
2011
- 2011-01-07 DO DO2011000011A patent/DOP2011000011A/es unknown
- 2011-01-07 ZA ZA2011/00223A patent/ZA201100223B/en unknown
- 2011-01-14 CO CO11003597A patent/CO6331424A2/es not_active Application Discontinuation
-
2012
- 2012-08-03 US US13/565,872 patent/US20120302555A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100010062A1 (en) | 2010-01-14 |
| CN102088961A (zh) | 2011-06-08 |
| EP2317987B1 (en) | 2014-04-23 |
| DOP2011000011A (es) | 2011-01-31 |
| AR072477A1 (es) | 2010-09-01 |
| EP2317987A1 (en) | 2011-05-11 |
| IL210001A0 (en) | 2011-02-28 |
| CO6331424A2 (es) | 2011-10-20 |
| MX2011000349A (es) | 2011-02-22 |
| BRPI0915455A2 (pt) | 2017-06-27 |
| ECSP10010701A (es) | 2011-01-31 |
| UA100434C2 (en) | 2012-12-25 |
| EA201170182A1 (ru) | 2011-08-30 |
| CA2730008A1 (en) | 2010-01-14 |
| NZ589904A (en) | 2012-08-31 |
| JP2011527314A (ja) | 2011-10-27 |
| WO2010003996A1 (en) | 2010-01-14 |
| US20120302555A1 (en) | 2012-11-29 |
| ZA201100223B (en) | 2011-10-26 |
| AU2009268044A1 (en) | 2010-01-14 |
| KR20110031226A (ko) | 2011-03-24 |
| TW201006826A (en) | 2010-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |