PE20090524A1 - Composicion farmaceutica que comprende la combinacion de una triazolobenzodiazepina y un agente inhibidor selectivo de la recaptura de serotonina - Google Patents
Composicion farmaceutica que comprende la combinacion de una triazolobenzodiazepina y un agente inhibidor selectivo de la recaptura de serotoninaInfo
- Publication number
- PE20090524A1 PE20090524A1 PE2008001132A PE2008001132A PE20090524A1 PE 20090524 A1 PE20090524 A1 PE 20090524A1 PE 2008001132 A PE2008001132 A PE 2008001132A PE 2008001132 A PE2008001132 A PE 2008001132A PE 20090524 A1 PE20090524 A1 PE 20090524A1
- Authority
- PE
- Peru
- Prior art keywords
- pharmaceutical composition
- combination
- triazolobenzodiazepine
- composition
- composition including
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940076279 serotonin Drugs 0.000 title abstract 2
- 229940124639 Selective inhibitor Drugs 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- KYTREVLPRJOBEM-UHFFFAOYSA-N triazolo[4,5-i][1,2]benzodiazepine Chemical compound C1=CC2=CC=CN=NC2=C2C1=NN=N2 KYTREVLPRJOBEM-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 abstract 2
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 2
- 229960002296 paroxetine Drugs 0.000 abstract 2
- VREFGVBLTWBCJP-UHFFFAOYSA-N alprazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1 VREFGVBLTWBCJP-UHFFFAOYSA-N 0.000 abstract 1
- 229960004538 alprazolam Drugs 0.000 abstract 1
- 230000003001 depressive effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000037870 generalized anxiety Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONTIENE: A) UN AGENTE INHIBIDOR SELECTIVO DE LA RECAPTACION DE SEROTONINA TAL COMO PAROXETINA HEMIDRATO DEL COLHIDRATO DE PAROXETINA QUE SE ENCUENTRA EN UNA CANTIDAD DE 20 mg A 40 mg; B) UN AGENTE PERTENECIENTE AL GRUPO DE LAS TRIAZOLOBENZODIACEPINAS TAL COMO ALPRAZOLAM QUE SE ENCUENTRA EN UNA CANTIDAD DE 0.25 mg A 4.0 mg EN LA COMPOSICION. DICHA COMPOSICION ES UNA COMBINACION SINERGICA QUE REDUCE LOS EFECTOS SECUNDARIOS ASI COMO EL RIESGO DE DEPENDENCIA AL MEDICAMENTO EN COMPARACION CON LA ADMINISTRACION EN FORMA INDEPENDIENTE SIENDO UTIL EN EL TRATAMIENTO Y CONTROL DE EPISODIOS DEPRESIVOS MAYORES, SINTOMAS DEL TRSTORNO OBESIVO-COMPULSIVO (TOC), TRASTORNOS DE ANSIEDAD GENERALIZADA, ENTRE OTROS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2007008321A MX2007008321A (es) | 2007-07-06 | 2007-07-06 | Composicion farmaceutica que comprende la combinacion de una triazolobenzodiazepina y un agente inhibidor selectivo de la recaptura de serotonina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20090524A1 true PE20090524A1 (es) | 2009-05-20 |
Family
ID=40228772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2008001132A PE20090524A1 (es) | 2007-07-06 | 2008-07-04 | Composicion farmaceutica que comprende la combinacion de una triazolobenzodiazepina y un agente inhibidor selectivo de la recaptura de serotonina |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2168584B1 (es) |
| AR (1) | AR067450A1 (es) |
| BR (1) | BRPI0812988A2 (es) |
| CO (1) | CO6251272A2 (es) |
| CY (1) | CY1115876T1 (es) |
| EC (1) | ECSP109854A (es) |
| ES (1) | ES2524453T3 (es) |
| GT (1) | GT201000002A (es) |
| MX (1) | MX2007008321A (es) |
| PE (1) | PE20090524A1 (es) |
| PL (1) | PL2168584T3 (es) |
| WO (1) | WO2009008696A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9174216B2 (en) | 2013-03-13 | 2015-11-03 | DeNovo Science, Inc. | System for capturing and analyzing cells |
| US9404864B2 (en) | 2013-03-13 | 2016-08-02 | Denovo Sciences, Inc. | System for imaging captured cells |
| ES2797448T3 (es) | 2011-08-01 | 2020-12-02 | Bio Rad Laboratories | Sistema de captura de células |
| US10466160B2 (en) | 2011-08-01 | 2019-11-05 | Celsee Diagnostics, Inc. | System and method for retrieving and analyzing particles |
| US9707562B2 (en) | 2013-03-13 | 2017-07-18 | Denovo Sciences, Inc. | System for capturing and analyzing cells |
| US10391490B2 (en) | 2013-05-31 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
-
2007
- 2007-07-06 MX MX2007008321A patent/MX2007008321A/es active IP Right Grant
-
2008
- 2008-07-04 WO PCT/MX2008/000085 patent/WO2009008696A1/es not_active Ceased
- 2008-07-04 BR BRPI0812988-6A2A patent/BRPI0812988A2/pt not_active Application Discontinuation
- 2008-07-04 EP EP08778975.6A patent/EP2168584B1/en not_active Not-in-force
- 2008-07-04 PE PE2008001132A patent/PE20090524A1/es not_active Application Discontinuation
- 2008-07-04 ES ES08778975.6T patent/ES2524453T3/es active Active
- 2008-07-04 AR ARP080102904A patent/AR067450A1/es unknown
- 2008-07-04 PL PL08778975T patent/PL2168584T3/pl unknown
-
2009
- 2009-12-30 CO CO09149219A patent/CO6251272A2/es not_active Application Discontinuation
-
2010
- 2010-01-06 GT GT201000002A patent/GT201000002A/es unknown
- 2010-01-06 EC EC2010009854A patent/ECSP109854A/es unknown
-
2014
- 2014-11-10 CY CY20141100932T patent/CY1115876T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007008321A (es) | 2009-02-18 |
| GT201000002A (es) | 2016-01-21 |
| CO6251272A2 (es) | 2011-02-21 |
| WO2009008696A1 (es) | 2009-01-15 |
| ES2524453T3 (es) | 2014-12-09 |
| ECSP109854A (es) | 2010-02-26 |
| AR067450A1 (es) | 2009-10-14 |
| EP2168584A1 (en) | 2010-03-31 |
| EP2168584A4 (en) | 2010-07-07 |
| CY1115876T1 (el) | 2017-01-25 |
| PL2168584T3 (pl) | 2015-03-31 |
| BRPI0812988A2 (pt) | 2014-12-16 |
| EP2168584B1 (en) | 2014-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |