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PE20081463A1 - Formas salinas de compuestos de benzotienilo sustituido - Google Patents

Formas salinas de compuestos de benzotienilo sustituido

Info

Publication number
PE20081463A1
PE20081463A1 PE2007001405A PE2007001405A PE20081463A1 PE 20081463 A1 PE20081463 A1 PE 20081463A1 PE 2007001405 A PE2007001405 A PE 2007001405A PE 2007001405 A PE2007001405 A PE 2007001405A PE 20081463 A1 PE20081463 A1 PE 20081463A1
Authority
PE
Peru
Prior art keywords
methyl
salt
benzothynyl
compounds
alcoxy
Prior art date
Application number
PE2007001405A
Other languages
English (en)
Inventor
Luigi Anzalone
Frank John Villani
Penina Feibush
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PE20081463A1 publication Critical patent/PE20081463A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE REFIERE A FORMAS SALINAS DE UN COMPUESTO DE BENZOTIENILO SUSTITUIDO DE FORMUAL (I), EN DONDE R1 ES UNO O DOS HALOGENOS; R2 ES ALQUILO(C1-C4), ALCOXI (C1-C4), ALCOXI(C1-C4)CARBONILOXI-ALCOXI(C1-C4), ENTRE OTROS; DONDE LA FORMA SALINA ESTA SELECCIONADA DEL GRUPO QUE CONSISTE EN UNA FORMA MONO-SAL O DI-SAL, SELECCIONADA DE BENZATINA, t-BUTILAMINA, MAGNESIO, CALCIO, COLINA, CICLOHEXILAMINA, DIETANOLAMINA, ETILENDIAMINA, L-LISINA, NH3, HN4OH, N-METIL-D-GLUCAMINA, TRIS(HIDROXIMETIL)METILAMINA, ENTRE OTROS. SON SELECCIONADOS: SAL MONOCOLINA DE (E)-{(5-CLORO-BENZO[b]TIOFEN-3-IL)-[2-(3,4-DIFLUOR-FENIL)-VINILCARBAMOIL]-METIL}-METIL-FOSFINICO, SAL MONO COLINA DE ACIDO (E)-{(5-CLORO-BENZO[b]TIOFEN-3-IL)-[2-(3,5-DICLORO-FENIL)-VINILCARBAMOIL]-METIL}-FOSFONICO, ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION, ESTOS COMPUESTOS SON INHIBIDORES DEL RECEPTOR DE QUINASA
PE2007001405A 2006-10-20 2007-10-17 Formas salinas de compuestos de benzotienilo sustituido PE20081463A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85340706P 2006-10-20 2006-10-20

Publications (1)

Publication Number Publication Date
PE20081463A1 true PE20081463A1 (es) 2008-10-18

Family

ID=39325140

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001405A PE20081463A1 (es) 2006-10-20 2007-10-17 Formas salinas de compuestos de benzotienilo sustituido

Country Status (20)

Country Link
US (1) US20080097110A1 (es)
EP (1) EP2081430A4 (es)
JP (1) JP2010506933A (es)
KR (1) KR20090069331A (es)
CN (1) CN101583272A (es)
AR (1) AR063342A1 (es)
AU (1) AU2007309463A1 (es)
BR (1) BRPI0718168A2 (es)
CA (1) CA2667197A1 (es)
CL (1) CL2007003011A1 (es)
EA (1) EA200900574A1 (es)
EC (1) ECSP099267A (es)
IL (1) IL198224A0 (es)
MX (1) MX2009004206A (es)
NI (1) NI200900060A (es)
NO (1) NO20091971L (es)
PE (1) PE20081463A1 (es)
TW (1) TW200821291A (es)
UY (1) UY30648A1 (es)
WO (1) WO2008051489A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102837123B1 (ko) * 2021-03-03 2025-07-21 주식회사 엘지화학 폴리옥틸티오펜의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022582A2 (en) * 2000-09-14 2002-03-21 Ortho-Mcneil Pharmaceutical, Inc. Solid salt forms of n-[2-[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]ethyl]-2-oxo-1-piperidineacetamide
GB0314136D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
CN1934120B (zh) * 2004-01-23 2010-05-26 詹森药业有限公司 新的胃促胰酶抑制剂

Also Published As

Publication number Publication date
IL198224A0 (en) 2009-12-24
CA2667197A1 (en) 2008-05-02
EP2081430A2 (en) 2009-07-29
JP2010506933A (ja) 2010-03-04
NO20091971L (no) 2009-05-20
AR063342A1 (es) 2009-01-21
UY30648A1 (es) 2008-05-02
ECSP099267A (es) 2009-11-30
KR20090069331A (ko) 2009-06-30
TW200821291A (en) 2008-05-16
EP2081430A4 (en) 2010-11-10
AU2007309463A1 (en) 2008-05-02
US20080097110A1 (en) 2008-04-24
BRPI0718168A2 (pt) 2013-11-26
CL2007003011A1 (es) 2008-04-18
WO2008051489A2 (en) 2008-05-02
WO2008051489A3 (en) 2008-07-10
MX2009004206A (es) 2009-04-30
CN101583272A (zh) 2009-11-18
NI200900060A (es) 2010-02-01
EA200900574A1 (ru) 2009-10-30

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