PE20080845A1 - Metodo para fabricar tabletas que contienen agentes farmacologicamente activos - Google Patents
Metodo para fabricar tabletas que contienen agentes farmacologicamente activosInfo
- Publication number
- PE20080845A1 PE20080845A1 PE2007001268A PE2007001268A PE20080845A1 PE 20080845 A1 PE20080845 A1 PE 20080845A1 PE 2007001268 A PE2007001268 A PE 2007001268A PE 2007001268 A PE2007001268 A PE 2007001268A PE 20080845 A1 PE20080845 A1 PE 20080845A1
- Authority
- PE
- Peru
- Prior art keywords
- active agents
- pharmacologically active
- tablets containing
- containing pharmacologically
- manufacturing tablets
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 abstract 1
- 239000004605 External Lubricant Substances 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 239000001744 Sodium fumarate Substances 0.000 abstract 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000004141 Sodium laurylsulphate Substances 0.000 abstract 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 abstract 1
- 239000008116 calcium stearate Substances 0.000 abstract 1
- 235000013539 calcium stearate Nutrition 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000005056 compaction Methods 0.000 abstract 1
- MSJMDZAOKORVFC-SEPHDYHBSA-L disodium fumarate Chemical compound [Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O MSJMDZAOKORVFC-SEPHDYHBSA-L 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Substances [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 1
- 229960002446 octanoic acid Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000704 physical effect Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229940005573 sodium fumarate Drugs 0.000 abstract 1
- 235000019294 sodium fumarate Nutrition 0.000 abstract 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 1
- XUHVCHNJCBBXMP-UHFFFAOYSA-M sodium;10-[(2-hydroxybenzoyl)amino]decanoate Chemical compound [Na+].OC1=CC=CC=C1C(=O)NCCCCCCCCCC([O-])=O XUHVCHNJCBBXMP-UHFFFAOYSA-M 0.000 abstract 1
- UOENJXXSKABLJL-UHFFFAOYSA-M sodium;8-[(2-hydroxybenzoyl)amino]octanoate Chemical compound [Na+].OC1=CC=CC=C1C(=O)NCCCCCCCC([O-])=O UOENJXXSKABLJL-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONSTA DE UN LUBRICANTE EXTERNO TAL COMO ESTEARATO DE MAGNESIO O CALCIO, FUMARATO DE SODIO,LAURIL-SULFATO DE SODIO, ENTRE OTROS, PARA LA COMPACTACION DE UNA MEZCLA QUE CONTIENE: a) UN PRINCIPIO ACTIVO TAL COMO PROTEINA, POLIPEPTIDO, HORMONA, POLISACARIDO, CARBOHIDRATO, LIPIDO, O UNA COMBINACION DE LOS MISMOS; b) UN AGENTE DE SUMINISTRO, COMO, ACIDO N-(5-CLORO-SALICILOIL)-8-AMINO-CAPRILICO (5-CNAC), ACIDO N-(10-[2-HIDROXI-BENZOIL]-AMINO)-DECANOICO (SNAD), ACIDO N-(8-[2-HIDROXI-BENZOIL]-AMINO)-CAPRILICO (SNAC), O UNA COMBINACION DE LOS MISMOS. DICHA COMPOSICION HACE REFERENCIA A UNA MEJORA EN LAS PROPIEDADES FISICAS DE LA TABLETA TALES COMO, DUREZA, TIEMPO DE DESINTEGRACION Y DISOLUCION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82659706P | 2006-09-22 | 2006-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080845A1 true PE20080845A1 (es) | 2008-08-13 |
Family
ID=39227036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007001268A PE20080845A1 (es) | 2006-09-22 | 2007-09-20 | Metodo para fabricar tabletas que contienen agentes farmacologicamente activos |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR062925A1 (es) |
| CL (1) | CL2007002724A1 (es) |
| PE (1) | PE20080845A1 (es) |
| TW (1) | TW200820993A (es) |
| WO (1) | WO2008039351A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS56998B1 (sr) | 2010-12-16 | 2018-05-31 | Novo Nordisk As | Čvrste kompozicije koje sadrže agonist glp-1 i so n-(8-(2-hidroksibenzoil)amino)kaprilne kiseline |
| MY161450A (en) | 2011-04-12 | 2017-04-14 | Novo Nordisk As | Double-acylated glp-1 derivatives |
| HUE064694T2 (hu) | 2012-03-22 | 2024-04-28 | Novo Nordisk As | Továbbítószert tartalmazó készítmények és elõállításuk |
| ES2715308T3 (es) | 2012-03-22 | 2019-06-03 | Novo Nordisk As | Composiciones que comprenden un agente de suministro y su preparación |
| LT2827885T (lt) | 2012-03-22 | 2018-10-10 | Novo Nordisk A/S | Glp-1 peptidų kompozicijos ir jų gavimas |
| JP6517690B2 (ja) | 2012-06-20 | 2019-05-22 | ノヴォ ノルディスク アー／エス | ペプチド及び送達剤を含む錠剤製剤 |
| JP6672140B2 (ja) | 2013-05-02 | 2020-03-25 | ノヴォ ノルディスク アー／エス | Ｇｌｐ−１化合物の経口投薬 |
| MX2020007598A (es) | 2018-02-02 | 2020-09-03 | Novo Nordisk As | Composiciones solidas que comprenden un agonista del peptido similar al glucagon tipo 1 (glp-1), una sal del acido n-(8-(2-hidroxibenzoil)amino)caprilico y un lubricante. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2327655C (en) * | 1998-04-08 | 2010-03-09 | Kyowa Hakko Kogyo Co., Ltd. | Tablet production method and tablet |
| WO2005004900A1 (en) * | 2003-07-11 | 2005-01-20 | Novartis Ag | Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form |
-
2007
- 2007-09-20 WO PCT/US2007/020406 patent/WO2008039351A2/en not_active Ceased
- 2007-09-20 PE PE2007001268A patent/PE20080845A1/es not_active Application Discontinuation
- 2007-09-20 AR ARP070104166A patent/AR062925A1/es unknown
- 2007-09-21 CL CL200702724A patent/CL2007002724A1/es unknown
- 2007-09-21 TW TW096135632A patent/TW200820993A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008039351A2 (en) | 2008-04-03 |
| AR062925A1 (es) | 2008-12-17 |
| WO2008039351A3 (en) | 2008-06-19 |
| TW200820993A (en) | 2008-05-16 |
| CL2007002724A1 (es) | 2008-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |