PE20080712A1 - Tratamiento de fibrosis cistica con antibioticos por via de suministro de un torbellinador - Google Patents
Tratamiento de fibrosis cistica con antibioticos por via de suministro de un torbellinadorInfo
- Publication number
- PE20080712A1 PE20080712A1 PE2007000681A PE2007000681A PE20080712A1 PE 20080712 A1 PE20080712 A1 PE 20080712A1 PE 2007000681 A PE2007000681 A PE 2007000681A PE 2007000681 A PE2007000681 A PE 2007000681A PE 20080712 A1 PE20080712 A1 PE 20080712A1
- Authority
- PE
- Peru
- Prior art keywords
- treatment
- dextrose
- injection
- fibrosis
- cyystic
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 206010016654 Fibrosis Diseases 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 230000004761 fibrosis Effects 0.000 title 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 3
- 239000008121 dextrose Substances 0.000 abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- LPQZKKCYTLCDGQ-WEDXCCLWSA-N tazobactam Chemical compound C([C@]1(C)S([C@H]2N(C(C2)=O)[C@H]1C(O)=O)(=O)=O)N1C=CN=N1 LPQZKKCYTLCDGQ-WEDXCCLWSA-N 0.000 abstract 2
- 229960003865 tazobactam Drugs 0.000 abstract 2
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008263 liquid aerosol Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- IVBHGBMCVLDMKU-GXNBUGAJSA-N piperacillin Chemical compound O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 IVBHGBMCVLDMKU-GXNBUGAJSA-N 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- TUPFOYXHAYOHIB-YCAIQWGJSA-M sodium;(2s,5r,6r)-6-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2s,3s,5r)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0]h Chemical compound [Na+].C([C@]1(C)S([C@H]2N(C(C2)=O)[C@H]1C(O)=O)(=O)=O)N1C=CN=N1.O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 TUPFOYXHAYOHIB-YCAIQWGJSA-M 0.000 abstract 1
- 239000008227 sterile water for injection Substances 0.000 abstract 1
- FPZLLRFZJZRHSY-HJYUBDRYSA-N tigecycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FPZLLRFZJZRHSY-HJYUBDRYSA-N 0.000 abstract 1
- 229940061267 tygacil Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 229940104666 zosyn Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA COMPOSICION EN AEROSOL LIQUIDA QUE COMPRENDE UNA DROGA ANTIBIOTICA TAL COMO ZOSYN(PIPERACICLINA Y TAZOBACTAM), PIPERACILINA, TAZOBACTAM O TYGACIL (TIGLECICLINA); Y UN DILUYENTE QUE COMPRENDE AGUA ESTERIL PARA INYECCION, 0.9% DE CLORURO DE SODIO PARA INYECCION, 5% DE DEXTROSA PARA INYECCION; 5% DE DEXTROSA, 5% DE DEXTROSA, ENTRE OTROS, EL CUAL SE COLOCA EN EL DEPOSITO DEL SISTEMA DE SUMINISTRO DE DROGA EN AEROSOL SWIRLER, QUE SE CONECTA A UNA FUENTE DE GAS PRESURIZADA, EN DONDE EL TAMANO DE LAS PARTICULAS OBTENIDAS ES DE AL MENOS 90% DE LAS GOTAS DE 1 A 3 MICRONES O MENOS. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES RESPIRATORIAS TAL COMO LA FIBROSIS CISTICA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81167106P | 2006-06-07 | 2006-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080712A1 true PE20080712A1 (es) | 2008-05-22 |
Family
ID=38657254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007000681A PE20080712A1 (es) | 2006-06-07 | 2007-06-01 | Tratamiento de fibrosis cistica con antibioticos por via de suministro de un torbellinador |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR061263A1 (es) |
| PE (1) | PE20080712A1 (es) |
| TW (1) | TW200815003A (es) |
| WO (1) | WO2007145866A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641249A (zh) * | 2012-05-06 | 2012-08-22 | 江苏奥赛康药业股份有限公司 | 一种替加环素组合物的制备方法 |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| US20140274990A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
| DK2893929T3 (da) | 2013-03-15 | 2025-07-07 | Merck Sharp & Dohme Llc | Antibiotisk ceftolozansammensætninger |
| AU2014233637A1 (en) | 2013-09-09 | 2015-03-26 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
| US9566399B1 (en) | 2015-04-14 | 2017-02-14 | Clempharma LLC | Deep lung alveolar aerosol targeted drug delivery |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508269A (en) * | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| US5611332A (en) * | 1995-03-22 | 1997-03-18 | Bono; Michael | Aerosol inhalation device containing a rain-off chamber |
| AU2003225689B2 (en) * | 2002-03-05 | 2009-03-26 | Transave, Inc. | Methods for entrapment of bioactive agent in a liposome or lipid complex |
-
2007
- 2007-06-01 PE PE2007000681A patent/PE20080712A1/es not_active Application Discontinuation
- 2007-06-01 WO PCT/US2007/013065 patent/WO2007145866A1/en not_active Ceased
- 2007-06-05 TW TW096120156A patent/TW200815003A/zh unknown
- 2007-06-07 AR ARP070102454A patent/AR061263A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007145866A1 (en) | 2007-12-21 |
| TW200815003A (en) | 2008-04-01 |
| AR061263A1 (es) | 2008-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |