PE20040121A1 - Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno - Google Patents
Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaenoInfo
- Publication number
- PE20040121A1 PE20040121A1 PE2002001135A PE2002001135A PE20040121A1 PE 20040121 A1 PE20040121 A1 PE 20040121A1 PE 2002001135 A PE2002001135 A PE 2002001135A PE 2002001135 A PE2002001135 A PE 2002001135A PE 20040121 A1 PE20040121 A1 PE 20040121A1
- Authority
- PE
- Peru
- Prior art keywords
- matrix
- triazatetraciclo
- pentaene
- hexadeca
- controlled release
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE a: UNA FORMA DE DOSIFICACION DE LIBERACION CONTROLADA PARA LA ADMINISTRACION DE 5,8,14-TRIAZATETRACICLO[10.3.1.0(2,11).0(4,9)]-HEXADECA-2(11),3,5,7,9-PENTAENO,TAMBIEN CONOCIDO COMO 7,8,9,10-TETRAHIDRO-6,10-METANO-6H-PIRAZINO[2,3-h][3]-BENZAZEPINA O SU SAL TARTRATO O CITRATO LIBERANDOSE A UNA VELOCIDAD DE MENOS DE ALREDEDOR 6 MG/HORA, SU MEDIO DE ADMINISTRACION COMPRENDE UN COMPRIMIDO RECUBIERTO, COMPRIMIDO MATRIZ, MULTIPARTICULADO MATRIZ O MULTIPARTICULADO RECUBIERTO MATRIZ, PUDIENDO SER LA MATRIZ HIDROFILA. b: UNA FORMA DE DOSIFICACION DE LIBERACION INMEDIATA, CON UN NIVEL TOTAL DE CARBOHIDRATOS REDUCTORES MENOR DE UN 20% EN PESO,DE PREFERENCIA COMPRENDE UN 77-91% DE EXCIPIENTE COMO MANITOL, SORBITOL, CELULOSA MICROCRISTALINA, ALMIDON, FOSFATO DICALCICO BASICO, ENTRE OTROS.LA FORMULACION PUEDE SER UTIL PARA REDUCIR LA ADICION A LA NICOTINA O AYUDAR EN EL CESE O REDUCCION DEL USO DEL TABACO EN TANTO QUE SE REDUCEN LAS NAUSEAS COMO EFECTO ADVERSO,O PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS EN EL INTESTINO, COLITIS ULCEROSA, PIODERMIA GANGRENOSA, ENFERMEDAD DE CROHN, SINDROME DE INTESTINO IRRITABLE, DISTONIA ESPASTICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33465201P | 2001-11-30 | 2001-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20040121A1 true PE20040121A1 (es) | 2004-03-22 |
Family
ID=23308160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002001135A PE20040121A1 (es) | 2001-11-30 | 2002-11-26 | Formulaciones farmaceuticas de liberacion controlada del 5,8,14-triazatetraciclo [10.3.1.02,11.04.9]-hexadeca-2-(11),3,5,7,9-pentaeno |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7771748B2 (es) |
| EP (1) | EP1448235B1 (es) |
| JP (2) | JP2005528330A (es) |
| KR (2) | KR20040063975A (es) |
| CN (2) | CN1596128A (es) |
| AR (1) | AR037592A1 (es) |
| AT (1) | ATE356625T1 (es) |
| AU (1) | AU2002351008B2 (es) |
| BR (1) | BR0214806A (es) |
| CA (1) | CA2467490C (es) |
| DE (1) | DE60218885T2 (es) |
| DK (1) | DK1448235T3 (es) |
| ES (1) | ES2282492T3 (es) |
| GT (1) | GT200200247A (es) |
| IL (1) | IL161857A0 (es) |
| MX (1) | MXPA04003807A (es) |
| MY (1) | MY130619A (es) |
| NO (1) | NO20042739L (es) |
| NZ (1) | NZ532435A (es) |
| PA (1) | PA8559501A1 (es) |
| PE (1) | PE20040121A1 (es) |
| PL (1) | PL208080B1 (es) |
| PT (1) | PT1448235E (es) |
| RU (2) | RU2272629C2 (es) |
| SI (1) | SI1448235T1 (es) |
| SV (1) | SV2004001418A (es) |
| TW (1) | TWI327471B (es) |
| UY (1) | UY27553A1 (es) |
| WO (1) | WO2003045437A1 (es) |
| ZA (1) | ZA200403068B (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1044189B2 (en) * | 1997-12-31 | 2015-02-25 | Pfizer Products Inc. | Aryl fused azapolycyclic compounds |
| SE521512C2 (sv) * | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
| CN1596128A (zh) | 2001-11-30 | 2005-03-16 | 辉瑞产品公司 | 5,7,14－三氮杂四环[10.3.1.0(2,11).0(4,9)]－十六碳－2(11)3,5,7,9－五烯的药物组合物 |
| ES2708551T3 (es) * | 2002-12-20 | 2019-04-10 | Niconovum Ab | Material particulado que contiene nicotina con una celulosa cristalina |
| EP1633358A1 (en) * | 2003-05-20 | 2006-03-15 | Pfizer Products Inc. | Pharmaceutical compositions of varenicline |
| US7051606B2 (en) * | 2004-01-30 | 2006-05-30 | Andrx Labs Llc | Dosage form holder device and methods for immersion testing |
| EP1802276A1 (en) * | 2004-10-15 | 2007-07-04 | Pfizer Products Inc. | Compositions and methods for intranasal, buccal, sublingual and pulmonary delivery of varenicline |
| CA2593432A1 (en) * | 2005-01-07 | 2006-07-13 | Prizer Products Inc. | Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene |
| US20110086086A1 (en) * | 2005-07-26 | 2011-04-14 | Pfizer Inc | Transdermal system for varenicline |
| UA91376C2 (ru) * | 2005-08-24 | 2010-07-26 | Рубикон Рисеч Пвт Лтд. | Рецептура с контролируемым высвобождением |
| EP1998748B1 (en) | 2006-03-16 | 2015-01-14 | NicoNovum AB | Improved snuff composition |
| BRPI0710914A2 (pt) * | 2006-04-24 | 2011-09-27 | Pfizer Prod Inc | forma de dosagem e método para o tratamento de dependência, adição e supressão de nicotina, em particular para uso na terapia para parar de fumar |
| WO2007132344A2 (en) * | 2006-05-09 | 2007-11-22 | Aurobindo Pharma Limited | Controlled release compositions of an antidepressant agent |
| US20080145423A1 (en) * | 2006-12-14 | 2008-06-19 | Ajmal Ali Khan | Chewable tablet and method of formulating |
| WO2009027786A2 (en) * | 2007-08-29 | 2009-03-05 | Pfizer Inc. | Matrix dosage forms of varenicline |
| WO2009034431A2 (en) | 2007-09-10 | 2009-03-19 | Pfizer Inc. | Controlled-release dosage forms for varenicline |
| WO2009123580A1 (en) * | 2008-04-01 | 2009-10-08 | Schering-Plough Healthcare Products, Inc. | Chewable tablet and method of formulating |
| US8039620B2 (en) | 2008-05-22 | 2011-10-18 | Teva Pharmaceutical Industries Ltd. | Varenicline tosylate, an intermediate in the preparation process of varenicline L-tartrate |
| US20090318695A1 (en) * | 2008-06-19 | 2009-12-24 | Vinod Kumar Kansal | Processes for the preparation of varenicline and intermediates thereof |
| US20100010221A1 (en) * | 2008-07-10 | 2010-01-14 | Revital Lifshitz-Liron | Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt |
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| JP2019501207A (ja) * | 2016-01-08 | 2019-01-17 | シーティーシー バイオ，インコーポレイテッド | バレニクリンまたはこの薬学的に許容可能な塩を含有する、味の遮蔽された口腔投与用薬学製剤 |
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