PE20040041A1 - Composicion farmaceutica que comprende flunixina - Google Patents
Composicion farmaceutica que comprende flunixinaInfo
- Publication number
- PE20040041A1 PE20040041A1 PE2003000481A PE2003000481A PE20040041A1 PE 20040041 A1 PE20040041 A1 PE 20040041A1 PE 2003000481 A PE2003000481 A PE 2003000481A PE 2003000481 A PE2003000481 A PE 2003000481A PE 20040041 A1 PE20040041 A1 PE 20040041A1
- Authority
- PE
- Peru
- Prior art keywords
- halogen
- acid
- phenyl
- flunixin
- deuterioethyl
- Prior art date
Links
- NOOCSNJCXJYGPE-UHFFFAOYSA-N flunixin Chemical compound C1=CC=C(C(F)(F)F)C(C)=C1NC1=NC=CC=C1C(O)=O NOOCSNJCXJYGPE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000588 flunixin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 AZIDOMETHYL Chemical class 0.000 abstract 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical group C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ZYVYEJXMYBUCMN-UHFFFAOYSA-N 1-methoxy-2-methylpropane Chemical class COCC(C)C ZYVYEJXMYBUCMN-UHFFFAOYSA-N 0.000 abstract 1
- 101100496169 Arabidopsis thaliana CLH1 gene Proteins 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 101100519284 Cercospora nicotianae PDX1 gene Proteins 0.000 abstract 1
- 206010010741 Conjunctivitis Diseases 0.000 abstract 1
- 208000004232 Enteritis Diseases 0.000 abstract 1
- 101100044057 Mesocricetus auratus SYCP3 gene Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 101100080600 Schizosaccharomyces pombe (strain 972 / ATCC 24843) nse6 gene Proteins 0.000 abstract 1
- 101100277598 Sorghum bicolor DES3 gene Proteins 0.000 abstract 1
- 206010046793 Uterine inflammation Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 101150111293 cor-1 gene Proteins 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
- 101150009274 nhr-1 gene Proteins 0.000 abstract 1
- 208000037935 pododermatitis Diseases 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 101150073238 sor1 gene Proteins 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
QUE COMPRENDE: a)FLUNIXINA O UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES; b)UN COMPUESTO DE FORMULA (I); Y, c)UN SOLVENTE POLAR APROTICO, SELECCIONADO DE: PIRROLIDONA, N,N-DIMETILACETAMIDA, N,N-DIMETILFORMAMIDA, DMSO, ACETONA, Y GLICEROL FORMAL; Y COMBINACIONES DE LOS MISMOS. DONDE, R ES SELECCIONADO DE METILO O ETILO, O UN DERIVADO HALOGENADO DE LOS MISMOS, DIHALOGENDEUTERIOMETILO, 1-HALOGEN-1-DEUTERIOETILO, 1,2-DIHALOGEN-1-DEUTERIOETILO, AZIDOMETILO Y METILSULFONILMETILO; CADA X Y X' ES SELECCIONADO DE MANERA INDEPENDIENTE DE: NO2, SO2R1, SOR1, SR1, SONH2, SO2NH2, SONHR1, SO2NHR1, COR1, OR1, R1, CN, HALOGENO, H, FENILO Y FENILO SUSTITUIDO CON HALOGENO, NO2, R1, PO2R1, CONHR1, NHR1, NR1R2, CONR1R2, OCOR1, u OR1 EN DONDE CADA UNO DE R1 Y R2 ES SELECCIONADO EN FORMA INDEPENDIENTE DE METILO, ETILO, n-PROPILO, ISOPROPILO, BUTILO, t-BUTILO, ISOBUTILO Y FENILO; Y, Z ES H O UN GRUPO ACILO DE UN ACIDO HIDROCARBONCARBOXILICO QUE TIENE HASTA 16 ATOMOS DE CARBONO, O UN GRUPO ACILO DE UN ACIDO AMINOHIDROCARBONCARBOXILICO QUE TIENE HASTA 12 ATOMOS DE CARBONO Y LAS SALES FARMACEUTICAMENTE ACEPTABLES DE DICHOS GRUPOS ACILO. LA COMPOSICION DESCRITA TIENE APLICACION EN EL TRATAMIENTO DE ENFERMEDADES COMO ENFERMEDADES RESPIRATORIAS BOVINAS, PORCINAS, PODODERMATITIS, MASTITIS AGUDA, CONJUNTIVITIS INFECCIOSA AGUDA, METRITIS Y ENTERITIS EN UN ANIMAL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38201502P | 2002-05-20 | 2002-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20040041A1 true PE20040041A1 (es) | 2004-01-24 |
Family
ID=29550174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003000481A PE20040041A1 (es) | 2002-05-20 | 2003-05-19 | Composicion farmaceutica que comprende flunixina |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US6790867B2 (es) |
| EP (1) | EP1505975B1 (es) |
| JP (2) | JP4772324B2 (es) |
| KR (1) | KR101102176B1 (es) |
| CN (1) | CN100563655C (es) |
| AR (1) | AR039826A1 (es) |
| AU (1) | AU2003228042B2 (es) |
| BR (1) | BRPI0311126B1 (es) |
| CA (1) | CA2485491C (es) |
| CY (1) | CY1107176T1 (es) |
| DE (1) | DE60317662T2 (es) |
| DK (1) | DK1505975T3 (es) |
| EC (1) | ECSP045442A (es) |
| ES (1) | ES2295583T3 (es) |
| IL (2) | IL165252A0 (es) |
| MX (1) | MXPA04011516A (es) |
| MY (1) | MY135791A (es) |
| NO (1) | NO20045547L (es) |
| NZ (1) | NZ536476A (es) |
| PE (1) | PE20040041A1 (es) |
| PL (1) | PL213975B1 (es) |
| PT (1) | PT1505975E (es) |
| RU (2) | RU2330662C2 (es) |
| SI (1) | SI1505975T1 (es) |
| TW (1) | TWI355266B (es) |
| UA (1) | UA81629C2 (es) |
| WO (1) | WO2003097054A1 (es) |
| ZA (1) | ZA200409296B (es) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10709850B2 (en) | 2018-06-15 | 2020-07-14 | James T. Doubet | Syringe adapter for medication |
| US11337894B2 (en) | 2018-06-15 | 2022-05-24 | James T. Doubet | Syringe adapter for animal medication |
| US11097058B2 (en) | 2018-06-15 | 2021-08-24 | James T. Doubet | Syringe adapter for medication |
| US11090444B2 (en) | 2018-06-15 | 2021-08-17 | James T. Doubet | Syringe adapter for medication |
| US6432203B1 (en) * | 1997-03-17 | 2002-08-13 | Applied Komatsu Technology, Inc. | Heated and cooled vacuum chamber shield |
| US20040208842A1 (en) * | 2001-09-18 | 2004-10-21 | Ritchie Branson W. | Antimicrobial cleansing compositions and methods of use |
| US20070003508A1 (en) | 2005-07-01 | 2007-01-04 | Wooley Richard E | Methods and compositions for promoting wound healing |
| US6787568B1 (en) * | 2000-11-27 | 2004-09-07 | Phoenix Scientific, Inc. | Antibiotic/analgesic formulation and a method of making this formulation |
| EP1446103B1 (en) * | 2001-10-19 | 2015-12-23 | Idexx Laboratories, Inc. | Injectable compositions for the controlled delivery of pharmacologically active compound |
| US6790867B2 (en) * | 2002-05-20 | 2004-09-14 | Schering-Plough Animal Health Corporation | Compositions and method for treating infection in cattle and swine |
| UA82359C2 (uk) * | 2003-04-03 | 2008-04-10 | Schering Plough Ltd | Композиція (варіанти) і спосіб лікування мікробних і паразитних інфекцій у великої рогатої худоби і інших тварин |
| MY146351A (en) | 2003-05-29 | 2012-08-15 | Schering Plough Ltd | Compositions for treating infection in cattle and swine |
| US7439268B2 (en) * | 2003-07-18 | 2008-10-21 | Idexx Laboratories | Compositions containing prodrugs of florfenicol and methods of use |
| WO2005044254A1 (en) * | 2003-10-29 | 2005-05-19 | Idexx Laboratories, Inc. | Salts of pharmacologically active compounds |
| KR100548948B1 (ko) * | 2003-11-24 | 2006-02-02 | 주식회사 한동 | 플로르페니콜의 약제학적 조성물 |
| US20070185202A1 (en) * | 2004-03-03 | 2007-08-09 | University Of Georgia Research Foundation, Inc. | Methods and compositions for ophthalmic treatment of fungal and bacterial infections |
| WO2007058639A2 (en) * | 2004-09-02 | 2007-05-24 | Idexx Laboratories Inc. | Antibacterial agents |
| ATE411046T1 (de) * | 2004-12-21 | 2008-10-15 | Intervet Int Bv | Injizierbare veterinärmedizinische zusammensetzung enthaltend florfenicol |
| US8119667B2 (en) * | 2005-12-29 | 2012-02-21 | Schering-Plough Animal Health Corporation | Carbonates of fenicol antibiotics |
| US7518017B2 (en) | 2006-02-17 | 2009-04-14 | Idexx Laboratories | Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds |
| CA2672795A1 (en) * | 2006-12-13 | 2008-06-26 | Schering-Plough Ltd. | Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof |
| EP2091909A1 (en) * | 2006-12-13 | 2009-08-26 | Schering-Plough Ltd. | Water-soluble prodrugs of florfenicol and its analogs |
| CA2672863A1 (en) * | 2006-12-19 | 2008-07-17 | Schering-Plough Ltd. | Effervescent formulations of florfenicol for addition in drinking water systems |
| PE20081406A1 (es) * | 2006-12-20 | 2008-10-17 | Schering Plough Ltd | Composiciones farmaceuticas de flunixina |
| RU2342656C2 (ru) * | 2007-01-09 | 2008-12-27 | Государственное образовательное учреждение высшего профессионального образования "Оренбургская медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ОрГМА Росздрава) | Способ прогнозирования осложненного течения флегмон |
| BRPI0810601A2 (pt) * | 2007-04-27 | 2014-10-21 | Schering Plough Ltd | Compostos e métodos para aumento da solubilidade de florfenicol e antibióticos estruturalmente relacionados usando ciclodextrinas |
| US7550625B2 (en) | 2007-10-19 | 2009-06-23 | Idexx Laboratories | Esters of florfenicol |
| US20090170954A1 (en) * | 2007-12-14 | 2009-07-02 | Schering-Plough Ltd. | Process for Recovering Florfenicol and Florfenicol Analogs |
| ES2384903T3 (es) | 2007-12-14 | 2012-07-13 | Intervet International B.V. | Proceso para recuperar flunixina a partir de composiciones farmacéuticas |
| FR2925334A1 (fr) * | 2007-12-21 | 2009-06-26 | Ceva Sante Animale Sa | Nouvelles compositions antibacteriennes |
| WO2009143558A1 (en) * | 2008-05-26 | 2009-12-03 | Silphion Pty Limited | Injectable formulations |
| CN101461821B (zh) * | 2008-07-04 | 2011-05-18 | 青岛康地恩药业有限公司 | 一种用于治疗猪、牛呼吸道疾病的复方口服药物组合物 |
| ES2963062T3 (es) | 2008-07-23 | 2024-03-25 | Ambrx Inc | Polipéptidos G-CSF bovinos modificados y sus usos |
| CN102131772B (zh) * | 2008-07-30 | 2015-03-11 | 英特威国际有限公司 | 用作氟苯尼考的中间体的*唑啉-保护的氨基二醇化合物的制备方法 |
| BRPI1002021A2 (pt) * | 2010-01-21 | 2012-05-22 | Nanocore Biotecnologia S A | composições farmacêuticas para tratamento de infecções bacterianas |
| TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
| CN102188422B (zh) * | 2011-01-11 | 2013-11-06 | 广东大华农动物保健品股份有限公司 | 一种复方氟苯尼考注射液及其制备方法和应用 |
| EA019956B1 (ru) * | 2011-02-24 | 2014-07-30 | Закрытое Акционерное Общество "Нита-Фарм" | Фармацевтическая композиция для лечения заболеваний бактериальной и микоплазменной этиологии |
| UA110436C2 (en) * | 2012-03-06 | 2015-12-25 | Zoetis Llc | Antibacterial phenol compounds |
| JP2015532279A (ja) * | 2012-09-26 | 2015-11-09 | ゾエティス・エルエルシー | フェニコール抗菌剤 |
| CN102920701A (zh) * | 2012-11-02 | 2013-02-13 | 青岛康地恩药业股份有限公司 | 一种用于治疗猪呼吸道感染疾病的复方氟苯尼考制剂及其制备方法 |
| CN104208062A (zh) * | 2013-06-03 | 2014-12-17 | 中国农业科学院兰州畜牧与兽药研究所 | 一种高浓度复方氟苯尼考注射液及其制备方法和应用 |
| CN104095996A (zh) * | 2014-08-12 | 2014-10-15 | 王忠亮 | 一种治疗急性脓肿期乳腺炎的药物组合物 |
| CN104188901A (zh) * | 2014-08-12 | 2014-12-10 | 河南迪冉生物科技有限公司 | 一种兽用氟苯尼考注射液及其制备方法 |
| CN104370782A (zh) * | 2014-11-29 | 2015-02-25 | 郑州后羿制药有限公司 | 一种氟苯尼考的精制方法 |
| RU2655772C1 (ru) * | 2016-12-26 | 2018-05-29 | Федеральное государственное бюджетное научное учреждение "Курский научно-исследовательский институт агропромышленного производства" | Йодсодержащий состав для лечения мастита у коров |
| US20190388625A1 (en) | 2018-06-15 | 2019-12-26 | James T. Doubet | Syringe adapter for medication |
| USD890925S1 (en) | 2018-06-15 | 2020-07-21 | James T. Doubet | Syringe adapter for medication |
| CN108904442B (zh) * | 2018-08-09 | 2021-04-06 | 山西瑞象生物药业有限公司 | 一种氟苯尼考溶液剂及其制备方法 |
| JP7532341B2 (ja) * | 2018-09-06 | 2024-08-13 | イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド | 注射可能な徐放性の抗生物質製剤 |
| CN110208397B (zh) * | 2019-05-17 | 2022-08-19 | 河北远征药业有限公司 | 一种同时测定土霉素氟尼辛注射液中两种主药含量的高效液相色谱法 |
| WO2022112277A1 (en) * | 2020-11-25 | 2022-06-02 | Intervet International B.V. | Method of treatment of pain through buccal administration of flunixin |
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| DE3025325A1 (de) * | 1980-07-04 | 1982-02-04 | Merck Patent Gmbh, 6100 Darmstadt | Neue 13-thiaprostaglandin-zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von 13-thiaprostaglandin-derivaten |
| US5082863A (en) * | 1990-08-29 | 1992-01-21 | Schering Corporation | Pharmaceutical composition of florfenicol |
| US5082653A (en) * | 1990-10-31 | 1992-01-21 | Warner-Lambert Company | Anti-plaque compositions comprising a combination of morpholinoamino alcohol and antibiotic |
| US5242910A (en) * | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| DE69707927T2 (de) | 1997-05-06 | 2002-04-11 | Norbrook Lab Ltd | Verbesserungen bezüglich langwirksamer antibiotika |
| JP2003512290A (ja) * | 1997-09-10 | 2003-04-02 | メルク エンド カムパニー インコーポレーテッド | 家畜抗菌剤としての８ａ−アザライド |
| US6423298B2 (en) * | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
| EP1202620A1 (en) * | 1999-05-14 | 2002-05-08 | The Regents of the University of California | Anti-inflammatory therapy for inflammatory mediated infection |
| US6787568B1 (en) | 2000-11-27 | 2004-09-07 | Phoenix Scientific, Inc. | Antibiotic/analgesic formulation and a method of making this formulation |
| US6790867B2 (en) * | 2002-05-20 | 2004-09-14 | Schering-Plough Animal Health Corporation | Compositions and method for treating infection in cattle and swine |
| MY146351A (en) | 2003-05-29 | 2012-08-15 | Schering Plough Ltd | Compositions for treating infection in cattle and swine |
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