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PE20040571A1 - Complejos de carbohidrato de hierro acuosos, su produccion y medicamentos que los contienen - Google Patents

Complejos de carbohidrato de hierro acuosos, su produccion y medicamentos que los contienen

Info

Publication number
PE20040571A1
PE20040571A1 PE2003001069A PE2003001069A PE20040571A1 PE 20040571 A1 PE20040571 A1 PE 20040571A1 PE 2003001069 A PE2003001069 A PE 2003001069A PE 2003001069 A PE2003001069 A PE 2003001069A PE 20040571 A1 PE20040571 A1 PE 20040571A1
Authority
PE
Peru
Prior art keywords
oxidation
iron
carbohydrate complexes
production
iii
Prior art date
Application number
PE2003001069A
Other languages
English (en)
Inventor
Peter Geisser
Erik Philipp
Walter Richle
Original Assignee
Vifor Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32102937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20040571(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vifor Int Ag filed Critical Vifor Int Ag
Publication of PE20040571A1 publication Critical patent/PE20040571A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
    • C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A COMPLEJOS DE CARBOHIDRATO DE HIERRO HIDROSOLUBLE QUE SE OBTIENEN A PARTIR DE DE UNA DISOLUCION ACUOSA DE UNA SAL DE HIERRO (III) PREFERENTEMENTE CLORURO DE HIERRO (III) Y DE UNA DISOLUCION ACUOSA DEL PRODUCTO DE OXIDACION DE UNA O MAS MALTODEXTRINAS CON UN EQUIVALENTE DE DEXTROSA DE 5 A 22, USANDO UNA DISOLUCION DE HIPOCLORITO ACUOSA TALES COMO HIPOCLORITOS ALCALINOS COMO EL HIPOCLORITO DE SODIO, A UN pH DE 8,5 A 12 .LA REACCION SE PUEDE LLEVAR A CABO A UNA TEMPERATURA DE 30°C HASTA EL PUNTO DE EBULLICION DURANTE 25 A 120 MINUTOS, ES POSIBLE CATALIZAR LA REACCION DE OXIDACION DE LAS MALTODEXTRINAS MEDIANTE LA ADICION DE IONES BROMURO EN LA FORMA DE BROMURO SODICO. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PRODUCCION Y A UN MEDICAMENTO QUE LO CONTIENE, EL CUAL ES UTIL PARA LA PROFILAXIS Y TRATAMIENTO DE ANEMIA FERROPENICA, SIENDO ESTOS MEDICAMENTOS DE APLICACION PARENTERAL
PE2003001069A 2002-10-23 2003-10-22 Complejos de carbohidrato de hierro acuosos, su produccion y medicamentos que los contienen PE20040571A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10249552A DE10249552A1 (de) 2002-10-23 2002-10-23 Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PE20040571A1 true PE20040571A1 (es) 2004-10-01

Family

ID=32102937

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003001069A PE20040571A1 (es) 2002-10-23 2003-10-22 Complejos de carbohidrato de hierro acuosos, su produccion y medicamentos que los contienen

Country Status (29)

Country Link
US (11) US7612109B2 (es)
EP (2) EP2287204B1 (es)
JP (2) JP4777653B2 (es)
KR (1) KR100992178B1 (es)
CN (1) CN100480275C (es)
AR (1) AR041472A1 (es)
AT (1) ATE507246T1 (es)
AU (1) AU2003278111C1 (es)
BR (2) BRPI0315452B8 (es)
CA (1) CA2493806C (es)
CY (2) CY1112680T1 (es)
DE (2) DE10249552A1 (es)
DK (2) DK2287204T3 (es)
ES (2) ES2385788T3 (es)
IL (1) IL166747A (es)
JO (3) JO3286B1 (es)
MX (1) MXPA05004300A (es)
MY (1) MY134394A (es)
NO (2) NO333008B1 (es)
NZ (1) NZ539243A (es)
PE (1) PE20040571A1 (es)
PT (2) PT2287204E (es)
RU (1) RU2303039C2 (es)
SA (1) SA03240447B1 (es)
SI (2) SI2287204T1 (es)
TW (1) TWI265028B (es)
UY (1) UY28033A1 (es)
WO (1) WO2004037865A1 (es)
ZA (1) ZA200504174B (es)

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