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PE20031013A1 - CANDIDA UTILIS QUE PRODUCE y-GLUTAMILCISTEINA - Google Patents

CANDIDA UTILIS QUE PRODUCE y-GLUTAMILCISTEINA

Info

Publication number
PE20031013A1
PE20031013A1 PE2003000299A PE2003000299A PE20031013A1 PE 20031013 A1 PE20031013 A1 PE 20031013A1 PE 2003000299 A PE2003000299 A PE 2003000299A PE 2003000299 A PE2003000299 A PE 2003000299A PE 20031013 A1 PE20031013 A1 PE 20031013A1
Authority
PE
Peru
Prior art keywords
candida utilis
food
drink
fraction
glutamilcysteine
Prior art date
Application number
PE2003000299A
Other languages
English (en)
Inventor
Hiroaki Nishiuchi
Yasushi Nishimura
Motonaka Kuroda
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20031013A1 publication Critical patent/PE20031013A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/24—Synthetic spices, flavouring agents or condiments prepared by fermentation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A23L31/10—Yeasts or derivatives thereof
    • A23L31/15—Extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14—Yeasts or derivatives thereof
    • A23L33/145—Extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y603/00—Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/02—Acid—amino-acid ligases (peptide synthases)(6.3.2)
    • C12Y603/02002—Glutamate-cysteine ligase (6.3.2.2)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

SE REFIERE A CANDIDA UTILIS QUE CONTIENE: a)1% POR PESO O MAS DE y-GLUTAMILCISTEINA EN CELULAS SECAS EN SU FASE LOGARITMICA DE DESARROLLO CUANDO SE CULTIVA EN UN MEDIO MINIMO, QUE MUESTRA UNA ACTIVIDAD DE LA SINTETASA DE GLUTATION DE 0,005 µmol DE GSH/mgproteina/hora O INFERIOR, DONDE EL GEN QUE CODIFICA LA SINTETASA SE MODIFICA DE MODO QUE SE REDUCE LA ACTIVIDAD INTRACELULAR DE LA SINTETASA DE GLUTATION. SE REFIERE TAMBIEN A UN ALIMENTO O BEBIDA QUE COMPRENDE EL CULTIVO OBTENIDO A PARTIR DEL CULTIVO DE LA CANDIDA UTILIS Y A UN METODO PARA PRODUCIR DICHO ALIMENTO, QUE COMPRENDE: 1)CULTIVAR LA CANDIDA UTILIS; 2)MEZCLAR EL CULTIVO OBTENIDO O UNA FRACCION DEL MISMO CON UNA MATERIA PRIMA DE ALIMENTO O BEBIDA PARA PRODUCIR UN ALIMENTO O BEBIDA. FINALMENTE SE REFIERE A: i)UNA PROTEINA QUE TIENE LA SECUENCIA AMINOACIDA DE LA SEC ID NO:43; Y, ii)UNA PROTEINA QUE TIENE LA SECUENCIA AMINOACIDA DE LA SEC ID NO:43, INCLUYENDO SUSTITUCION, ELIMINACION, INSERCION O ADICION DE UNO O VARIOS AMINOACIDOS Y TIENE UNA ACTIVIDAD DE LA SINTETASA DE y-GLUTAMILCISTEINA
PE2003000299A 2002-03-26 2003-03-25 CANDIDA UTILIS QUE PRODUCE y-GLUTAMILCISTEINA PE20031013A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002085058 2002-03-26

Publications (1)

Publication Number Publication Date
PE20031013A1 true PE20031013A1 (es) 2004-02-05

Family

ID=28449236

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000299A PE20031013A1 (es) 2002-03-26 2003-03-25 CANDIDA UTILIS QUE PRODUCE y-GLUTAMILCISTEINA

Country Status (9)

Country Link
US (1) US7553638B2 (es)
EP (2) EP2213734B1 (es)
JP (2) JP4561099B2 (es)
CN (1) CN1774505B (es)
AT (2) ATE532864T1 (es)
BR (2) BR0308630A (es)
MY (1) MY142328A (es)
PE (1) PE20031013A1 (es)
WO (1) WO2003080832A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003159048A (ja) * 2001-11-26 2003-06-03 Ajinomoto Co Inc γ−グルタミルシステイン産生酵母とそのスクリーニング法
JP2005073638A (ja) 2003-09-02 2005-03-24 Ajinomoto Co Inc キャンディダ・ユティリスのグルタチオン合成酵素をコードする遺伝子
JP5499714B2 (ja) 2008-02-15 2014-05-21 味の素株式会社 腸管免疫賦活剤
JPWO2009110624A1 (ja) 2008-03-04 2011-07-14 味の素株式会社 γ−グルタミルシステイン生産酵母及び酵母エキスの製造法
WO2011129462A2 (en) 2010-04-12 2011-10-20 Ajinomoto Co., Inc. A YEAST EXTRACT CONTAINING γ-Glu-X OR γ-Glu-X-Gly AND A METHOD FOR PRODUCING THE SAME
CN103348014B (zh) 2010-10-05 2020-11-03 味之素株式会社 含有γ-Glu-Abu的酵母和酵母提取物以及它们的制备方法
US10016472B2 (en) 2012-06-11 2018-07-10 William J. Kraemer Methods of mitigating the negative effects of resistance exercise
US20150150898A1 (en) * 2012-06-11 2015-06-04 Nu Science Laboratories, Inc. Nutritional products and methods of improving exercise performance and reducing exercise induced impairment of immune function
DE102013209274A1 (de) 2013-05-17 2014-11-20 Wacker Chemie Ag Mikroorganismus und Verfahren zur fermentativen Überproduktion von Gamma-Glutamylcystein und Derivaten dieses Dipeptids
WO2015005378A1 (ja) 2013-07-12 2015-01-15 味の素株式会社 Ａｂｕ、γ－Ｇｌｕ－Ａｂｕ、及び／又はγ－Ｇｌｕ－Ａｂｕ－Ｇｌｙを高含有する酵母
US10271570B2 (en) 2013-08-15 2019-04-30 Nu Science Laboratories, Inc. Compositions for and methods of diet supplementation
CN113621640B (zh) * 2021-09-01 2023-09-19 浙江华睿生物技术有限公司 构建谷氨酸-半胱氨酸二肽生产菌的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60156379A (ja) 1984-01-27 1985-08-16 Kohjin Co Ltd グルタチオン高含有酵母の製造方法
JPS6131081A (ja) * 1984-07-24 1986-02-13 Kohjin Co Ltd 変異株
JPS6152299A (ja) 1984-08-21 1986-03-14 Kanegafuchi Chem Ind Co Ltd 酵母によるグルタチオンの製造方法
JP2830415B2 (ja) * 1990-08-03 1998-12-02 味の素株式会社 フレーバー組成物の製造法
WO1994024276A1 (en) * 1993-04-08 1994-10-27 Cornell Research Foundation, Inc. Glutamylcysteine synthetase light subunit
IL109168A0 (en) * 1993-04-01 1994-06-24 Univ Columbia A retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and making cells resistant to the chemotherapeutic agent cyclophosphamide and its derivatives and analogs
CU22722A1 (es) * 1996-10-03 2002-02-28 Ct Ingenieria Genetica Biotech Sistema de transformación para la expresión de genes heterólogos en la levadura candida utilis
CN100366186C (zh) 1998-11-26 2008-02-06 味之素株式会社 食品风味增强用原材料的制造方法
MY128920A (en) * 2000-05-25 2007-02-28 Ajinomoto Kk METHOD FOR PRODUCING y-GLUTAMYLCYSTEINE
JP2003159048A (ja) 2001-11-26 2003-06-03 Ajinomoto Co Inc γ−グルタミルシステイン産生酵母とそのスクリーニング法
BRPI0400697B1 (pt) 2003-03-10 2015-07-28 Ajinomoto Co. Inc. Método para a produção de um material alimentício contendo uma alta quantidade de cisteína

Also Published As

Publication number Publication date
EP2213734A1 (en) 2010-08-04
US7553638B2 (en) 2009-06-30
MY142328A (en) 2010-11-15
EP1489173B1 (en) 2011-10-12
ATE528407T1 (de) 2011-10-15
CN1774505B (zh) 2011-04-20
ATE532864T1 (de) 2011-11-15
EP1489173A1 (en) 2004-12-22
WO2003080832A1 (en) 2003-10-02
JP4561099B2 (ja) 2010-10-13
BR0308630A (pt) 2005-02-15
EP2213734B1 (en) 2011-11-09
JPWO2003080832A1 (ja) 2005-07-28
EP1489173A4 (en) 2005-09-21
JP2009060920A (ja) 2009-03-26
JP4453781B2 (ja) 2010-04-21
CN1774505A (zh) 2006-05-17
BRPI0308630B1 (pt) 2015-05-12
US20050042328A1 (en) 2005-02-24

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