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PE20030331A1 - Melatonina y compuestos relacionados y medicamentos que los contienen para el tratamiento del insomnio primario - Google Patents

Melatonina y compuestos relacionados y medicamentos que los contienen para el tratamiento del insomnio primario

Info

Publication number
PE20030331A1
PE20030331A1 PE2002000731A PE2002000731A PE20030331A1 PE 20030331 A1 PE20030331 A1 PE 20030331A1 PE 2002000731 A PE2002000731 A PE 2002000731A PE 2002000731 A PE2002000731 A PE 2002000731A PE 20030331 A1 PE20030331 A1 PE 20030331A1
Authority
PE
Peru
Prior art keywords
melatonin
treatment
primary insomnia
antidepressants
related compounds
Prior art date
Application number
PE2002000731A
Other languages
English (en)
Inventor
Nava Zisapel
Original Assignee
Neurim Pharma 1991
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20030331(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharma 1991 filed Critical Neurim Pharma 1991
Publication of PE20030331A1 publication Critical patent/PE20030331A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

SE REFIERE A UN MEDICAMENTO QUE COMPRENDE MELATONINA, OTROS AGENTES MELATONERGICOS, AGONISTAS DE MELATONINA, ANTAGONISTAS DE MELATONINA, UTILIZANDO DE 0,0025 A 50mg; DILUYENTE, CONSERVANTE, ANTIOXIDANTE, SOLUBILIZANTE, EMULSIONANTE, COADYUVANTE QUE SE CARACTERIZADO POR i)FORMA DE ADMINISTRACION: ORAL, RECTAL PARENTERAL, TRANSBUCAL, INTRAPULMONAR, TRANSDERMICA; ii)FORMULACION DE LIBERACION PROLONGADA QUE INCLUYE ADEMAS UNA RESINA ACRILICA; iii)EN FORMA DE DEPOSITO QUE LIBERA MELATONINA; iv)LA FORMULACION COMPRENDE AL MENOS UN AGENTE TERAPEUTICO ADICIONAL COMO ANSIOLITICOS, ANTIDEPRESIVOS, HIPNOTICOS, SEDANTES, ANTIHIPERTENSIVOS, ANALGESICOS, AGONISTAS DOPAMINERGICOS, ANTIPSICOTICOS, TRANQUILIZANTES MENORES, ANORECTICOS, ANTIINFLAMATORIOS. EL MEDICAMENTO PUEDE SER UTIL PARA EL TRATAMIENTO Y MEJORA DE CALIDAD DE SUENO EN PACIENTE QUE SUFREN DE INSOMNIO PRIMARIO
PE2002000731A 2001-08-14 2002-08-13 Melatonina y compuestos relacionados y medicamentos que los contienen para el tratamiento del insomnio primario PE20030331A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs

Publications (1)

Publication Number Publication Date
PE20030331A1 true PE20030331A1 (es) 2003-06-27

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000731A PE20030331A1 (es) 2001-08-14 2002-08-13 Melatonina y compuestos relacionados y medicamentos que los contienen para el tratamiento del insomnio primario

Country Status (34)

Country Link
US (1) US8962024B2 (es)
EP (2) EP3103443B1 (es)
JP (1) JP2005501095A (es)
KR (1) KR20040032917A (es)
CN (1) CN100453078C (es)
AR (1) AR034975A1 (es)
AU (1) AU2002326114C1 (es)
BR (1) BR0211855A (es)
CA (1) CA2454699C (es)
CL (1) CL2002001701A1 (es)
CR (1) CR7271A (es)
CY (2) CY1118924T1 (es)
DK (2) DK1441702T3 (es)
EA (1) EA200400302A1 (es)
ES (2) ES2626591T3 (es)
GT (1) GT200200164A (es)
HU (1) HU230786B1 (es)
IL (1) IL144900A (es)
IS (1) IS3004B (es)
JO (1) JO3446B1 (es)
LT (1) LT1441702T (es)
MX (1) MXPA04001372A (es)
NO (1) NO334788B1 (es)
NZ (1) NZ531318A (es)
PA (1) PA8552301A1 (es)
PE (1) PE20030331A1 (es)
PL (1) PL367872A1 (es)
PT (2) PT3103443T (es)
RU (1) RU2560840C2 (es)
SI (1) SI1441702T1 (es)
UA (1) UA87262C2 (es)
UY (1) UY27401A1 (es)
WO (1) WO2003015690A2 (es)
ZA (1) ZA200402005B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
CA2682200C (en) 2007-03-19 2015-01-13 Vita Sciences, Llc Transdermal patch and method for delivery of vitamin b12
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) * 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
EP3337462B1 (en) 2016-10-31 2020-09-30 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

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EP0126630B1 (en) 1983-05-18 1987-09-16 Monash University The use of melatonin for the manufacture of a medicament
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ES2134789T3 (es) * 1991-05-09 1999-10-16 Neurim Pharma 1991 Composiciones que contienen melatonina.
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
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IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
US6703412B1 (en) 2002-09-27 2004-03-09 Holly A. Rosenthal Method of treating sleeplessness with melatonin on an acute basis
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Also Published As

Publication number Publication date
UA87262C2 (uk) 2009-07-10
HK1066161A1 (zh) 2005-03-18
US20040248966A1 (en) 2004-12-09
CY1124763T1 (el) 2022-07-22
SI1441702T1 (sl) 2017-08-31
ZA200402005B (en) 2005-07-27
PL367872A1 (en) 2005-03-07
UY27401A1 (es) 2003-02-28
EP3103443B1 (en) 2021-06-30
NO334788B2 (no) 2014-05-26
WO2003015690B1 (en) 2004-03-11
WO2003015690A2 (en) 2003-02-27
IL144900A0 (en) 2002-06-30
CL2002001701A1 (es) 2010-06-25
WO2003015690A3 (en) 2003-09-25
AU2002326114C1 (en) 2019-03-21
IS7136A (is) 2004-01-30
ES2882584T3 (es) 2021-12-02
EP1441702A2 (en) 2004-08-04
NO20040087L (no) 2004-02-19
CN1541092A (zh) 2004-10-27
JP2005501095A (ja) 2005-01-13
RU2011131532A (ru) 2013-03-27
BR0211855A (pt) 2004-09-21
US8962024B2 (en) 2015-02-24
NZ531318A (en) 2005-08-26
IL144900A (en) 2013-12-31
HUP0401042A3 (en) 2009-07-28
EP3103443A1 (en) 2016-12-14
AR034975A1 (es) 2004-03-24
DK3103443T3 (da) 2021-08-30
JO3446B1 (ar) 2020-07-05
MXPA04001372A (es) 2005-06-06
NO334788B1 (no) 2014-05-26
DK1441702T3 (en) 2017-06-06
CR7271A (es) 2004-05-17
CY1118924T1 (el) 2018-01-10
PA8552301A1 (es) 2003-06-30
CN100453078C (zh) 2009-01-21
ES2626591T3 (es) 2017-07-25
CA2454699A1 (en) 2003-02-27
HUP0401042A2 (hu) 2004-08-30
EP1441702B1 (en) 2017-05-10
GT200200164A (es) 2003-09-26
LT1441702T (lt) 2017-06-12
CA2454699C (en) 2012-03-27
EA200400302A1 (ru) 2004-10-28
AU2002326114B2 (en) 2007-03-08
PT3103443T (pt) 2021-08-12
IS3004B (is) 2018-09-15
KR20040032917A (ko) 2004-04-17
EP1441702A4 (en) 2007-09-26
HU230786B1 (en) 2018-05-02
PT1441702T (pt) 2017-06-02
AU2002326114A1 (en) 2003-03-03
RU2560840C2 (ru) 2015-08-20

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