PE20030434A1 - COMPUESTO DE ß-CETOAMIDA - Google Patents
COMPUESTO DE ß-CETOAMIDAInfo
- Publication number
- PE20030434A1 PE20030434A1 PE2002000740A PE2002000740A PE20030434A1 PE 20030434 A1 PE20030434 A1 PE 20030434A1 PE 2002000740 A PE2002000740 A PE 2002000740A PE 2002000740 A PE2002000740 A PE 2002000740A PE 20030434 A1 PE20030434 A1 PE 20030434A1
- Authority
- PE
- Peru
- Prior art keywords
- cetoamide
- alkyl group
- compound
- dioxobutanoate
- terc
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- -1 3-PHENYLPROPYL Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- ZNEMUOCEVAZZEQ-UHFFFAOYSA-N C(=O)C(C(=O)C(=O)O)N Chemical compound C(=O)C(C(=O)C(=O)O)N ZNEMUOCEVAZZEQ-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/80—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE ß-CETOAMIDA DE FORMULA I DONDE A ES UN ANILLO DE CARBONO DE C3-C10, HALOGENO, HIDROXIL, NITRO, ENTRE OTROS; X ES UN ENLACE, ALQUILENO DE C1-C6, ALQUENILO DE C2-C6,-NR4-, ENTRE OTROS; R1 ES UN GRUPO ALQUILO DE C1-C10, GRUPO ALQUENILO DE C2-C10, ENTRE OTROS; R2 ES -CO2R5, -CONR6R7, -COR8, ENTRE OTROS; R3 ES H, HALOGENO, ALQUILO C1-C4, ENTRE OTROS; R4 ES UN ATOMO DE H, UN GRUPO ALQUILO DE C1-4, -CO-, ENTRE OTROS; R5, R6, R7 Y R8 SON IGUALES O DIFERENTES Y CADA UNO ES H, UN GRUPO ALQUILO DE C1-C10, ENTRE OTROS. SON COMPUESTOS PREFERIDOS. BUTIL-TERC 4-[N-FENIL-N-(3-FENILPROPIL)]AMINO-2,4-DIOXOBUTANOATO. BUTIL-TERC 4-{N-(3-DIMETILCARBAMOIL)FENIL]-N-(2-NAFTILMETIL)AMINO}-2,4-DIOXOBUTANOATO, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA. LOS COMPUESTOS DE ß-CETOAMIDA SON UTILES COMO AGENTES ANTIVIRALES
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001247346 | 2001-08-16 | ||
| JP2001372066 | 2001-12-05 | ||
| JP2002151232 | 2002-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030434A1 true PE20030434A1 (es) | 2003-07-03 |
Family
ID=27347336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002000740A PE20030434A1 (es) | 2001-08-16 | 2002-08-15 | COMPUESTO DE ß-CETOAMIDA |
Country Status (2)
| Country | Link |
|---|---|
| PE (1) | PE20030434A1 (es) |
| WO (1) | WO2003016266A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003248872A1 (en) | 2002-07-09 | 2004-01-23 | Bristol-Myers Squibb Company | Hiv integrase inhibitors |
| GB0220187D0 (en) | 2002-08-30 | 2002-10-09 | Novartis Ag | Organic compounds |
| US7906537B2 (en) | 2003-03-21 | 2011-03-15 | H. Lundbeck A/S | Substituted p-diaminobenzene derivatives |
| TW200510425A (en) | 2003-08-13 | 2005-03-16 | Japan Tobacco Inc | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor |
| GB0815781D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| EP3915367A1 (en) | 2010-08-18 | 2021-12-01 | BioSplice Therapeutics, Inc. | Diketones and hydroxyketones as catenin signaling pathway activators |
| JP6401189B2 (ja) | 2013-02-22 | 2018-10-03 | サミュメッド リミテッド ライアビリティ カンパニー | Ｗｎｔ／β−カテニンシグナル伝達経路活性化剤としてのγ−ジケトン |
| HRP20192161T1 (hr) | 2014-08-20 | 2020-02-21 | Samumed, Llc | Gama-diketoni za liječenje i prevenciju starenja kože i bora |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07267903A (ja) * | 1994-03-31 | 1995-10-17 | Nagase & Co Ltd | 抗ｈｉｖ活性を有するフッ素含有化合物 |
| WO1999062520A1 (en) * | 1998-06-03 | 1999-12-09 | Merck & Co., Inc. | Hiv integrase inhibitors |
| EP1370510A2 (en) * | 2000-06-16 | 2003-12-17 | Bristol-Myers Squibb Company | Hiv integrase inhibitors |
-
2002
- 2002-08-12 WO PCT/JP2002/008211 patent/WO2003016266A1/ja not_active Ceased
- 2002-08-15 PE PE2002000740A patent/PE20030434A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003016266A1 (fr) | 2003-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |