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PE20020301A1 - Uso del fosfato de estramustina en el tratamiento de metastasis osea - Google Patents

Uso del fosfato de estramustina en el tratamiento de metastasis osea

Info

Publication number
PE20020301A1
PE20020301A1 PE2001000722A PE2001000722A PE20020301A1 PE 20020301 A1 PE20020301 A1 PE 20020301A1 PE 2001000722 A PE2001000722 A PE 2001000722A PE 2001000722 A PE2001000722 A PE 2001000722A PE 20020301 A1 PE20020301 A1 PE 20020301A1
Authority
PE
Peru
Prior art keywords
phosphate
stramustin
treatment
metastasis
osea
Prior art date
Application number
PE2001000722A
Other languages
English (en)
Inventor
Beryl Asp
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PE20020301A1 publication Critical patent/PE20020301A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE REFIERE AL USO DEL FOSFATO DE ESTRAMUSTINA ADMINISTRADO EN TERAPIA DE COMBINACION CON UN QUIMIOTERAPEUTICO ADICIONAL DENTRO DE UNA FORMULACION LIPOSOMAL SELECCIONADO DE DERIVADOS DE TAXANO, CAMPTOTECINA, GLICOSIDOS DE ANTRACICLINA, ETOPOSIDO, VINORELBINA, VINBLASTINA, CARBOPLATINO, CISPLATINO Y UN BISFOSFONATO ADICIONAL SELECCIONADO DE CLODRONATO, PALMIDRONATO, ETRIDONATO. EL FOSFATO DE ESTRAMUSTINA ES UN DERIVADO DE ESTRADIOL-17ß-FOSFATO UTIL PARA EL TRATAMIENTO DE LA REABSORCION OSEA Y ALIVIAR LOS SINTOMAS DE METASTASIS OSEA
PE2001000722A 2000-07-25 2001-07-17 Uso del fosfato de estramustina en el tratamiento de metastasis osea PE20020301A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/625,540 US6436913B1 (en) 2000-07-25 2000-07-25 Use of estramustine phosphate in the treatment of bone metastasis

Publications (1)

Publication Number Publication Date
PE20020301A1 true PE20020301A1 (es) 2002-04-07

Family

ID=24506563

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000722A PE20020301A1 (es) 2000-07-25 2001-07-17 Uso del fosfato de estramustina en el tratamiento de metastasis osea

Country Status (13)

Country Link
US (1) US6436913B1 (es)
EP (1) EP1328264A4 (es)
JP (1) JP2004504346A (es)
KR (1) KR20030019612A (es)
CN (1) CN1446086A (es)
AR (1) AR029958A1 (es)
AU (1) AU2001277115A1 (es)
BR (1) BR0112721A (es)
CA (1) CA2412392A1 (es)
MX (1) MXPA03000313A (es)
PE (1) PE20020301A1 (es)
WO (1) WO2002007719A1 (es)
ZA (1) ZA200210285B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003201D0 (en) * 2000-02-11 2000-04-05 Pharmacia & Upjohn Spa Method to potentiate the therapeutic efficacy of taxane and derivatives thereof
IT1318689B1 (it) * 2000-09-12 2003-08-27 Pharmacia & Upjohn Spa Uso dell'arginina nella preparazione di un medicamento per lapreparazione e trattamento degli effetti collaterali associati alla
US20040014729A1 (en) * 2001-07-23 2004-01-22 Beryl Asp Use of estramustine phosphate in the treatment of bone metastasis
CA2530279A1 (en) * 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
JP2005055881A (ja) * 2003-07-22 2005-03-03 Fuji Photo Film Co Ltd 描画方法および描画装置
CN100340296C (zh) * 2005-02-03 2007-10-03 山东蓝金生物工程有限公司 一种抗癌体内植入剂
WO2011066379A2 (en) * 2009-11-24 2011-06-03 H. Lee Moffitt Cancer Center And Research Institute, Inc. METHOD OF REDUCING INTRATUMORAL pHe AND ACID-MEDIATED INVASION

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634691A (en) * 1980-10-07 1987-01-06 The Procter & Gamble Company Method for inhibiting tumor metastasis
US5597830A (en) 1994-12-20 1997-01-28 Warner-Lambert Company Combination chemotherapy
BR9906425A (pt) * 1998-03-27 2000-07-11 Upjohn Co Métodos para potencializar fosfato de estramustina intravenoso
WO2000074634A2 (en) * 1999-06-03 2000-12-14 Au Jessie L S Methods and compositions for modulating cell proliferation and cell death

Also Published As

Publication number Publication date
CA2412392A1 (en) 2002-01-31
CN1446086A (zh) 2003-10-01
WO2002007719A1 (en) 2002-01-31
AU2001277115A1 (en) 2002-02-05
ZA200210285B (en) 2003-12-19
EP1328264A1 (en) 2003-07-23
US6436913B1 (en) 2002-08-20
JP2004504346A (ja) 2004-02-12
MXPA03000313A (es) 2003-06-06
KR20030019612A (ko) 2003-03-06
AR029958A1 (es) 2003-07-23
EP1328264A4 (en) 2004-01-28
BR0112721A (pt) 2003-06-24

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