PE20020466A1 - Combinacion de raloxifeno y exemestano para el tratamiento de cancer de mama - Google Patents
Combinacion de raloxifeno y exemestano para el tratamiento de cancer de mamaInfo
- Publication number
- PE20020466A1 PE20020466A1 PE2001000898A PE2001000898A PE20020466A1 PE 20020466 A1 PE20020466 A1 PE 20020466A1 PE 2001000898 A PE2001000898 A PE 2001000898A PE 2001000898 A PE2001000898 A PE 2001000898A PE 20020466 A1 PE20020466 A1 PE 20020466A1
- Authority
- PE
- Peru
- Prior art keywords
- raloxifene
- breast cancer
- exemestane
- treatment
- combination
- Prior art date
Links
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 title abstract 4
- 229960000255 exemestane Drugs 0.000 title abstract 4
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 229960004622 raloxifene Drugs 0.000 title abstract 2
- GZUITABIAKMVPG-UHFFFAOYSA-N raloxifene Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 GZUITABIAKMVPG-UHFFFAOYSA-N 0.000 title abstract 2
- AUYLVPGDOVEOML-UHFFFAOYSA-N [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(piperidin-1-ylmethoxy)phenyl]methanone Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 AUYLVPGDOVEOML-UHFFFAOYSA-N 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE AL USO DE UNA COMBINACION FARMACEUTICA QUE COMPRENDE RALOXIFENO Y EXEMESTANO Y SE ADMINISTRA ENTRE 5 mg/dia A 350 mg/dia DE RALOXIFENO Y ENTRE 5mg A 600mg DE EXEMESTANO. LA COMPOSICION COMPRENDE ALREDEDOR DE 2,4 PARTES EN PESO DE RALOXIFENO Y UNA PARTE EN PESO DE EXEMESTANO UTIL PARA PREVENIR E INHIBIR EL CANCER DE MAMA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65767000A | 2000-09-08 | 2000-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020466A1 true PE20020466A1 (es) | 2002-06-06 |
Family
ID=24638159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000898A PE20020466A1 (es) | 2000-09-08 | 2001-09-06 | Combinacion de raloxifeno y exemestano para el tratamiento de cancer de mama |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040009962A1 (es) |
| EP (1) | EP1315483A2 (es) |
| JP (1) | JP2004508325A (es) |
| AR (1) | AR034142A1 (es) |
| AU (1) | AU2001287028A1 (es) |
| PE (1) | PE20020466A1 (es) |
| WO (1) | WO2002020000A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040186185A1 (en) * | 1998-05-07 | 2004-09-23 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| GB0120147D0 (en) * | 2001-08-17 | 2001-10-10 | Metris Therapeutics Ltd | Treatment method |
| WO2003017973A1 (en) * | 2001-08-31 | 2003-03-06 | Pantarhei Bioscience B.V. | A method of treating benign gynaecological disorders and a drug delivery vehicle for use in such a method |
| US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
| GB0129457D0 (en) * | 2001-12-10 | 2002-01-30 | Astrazeneca Ab | Method of treatment |
| AU2003261233A1 (en) * | 2002-07-25 | 2004-02-16 | Massachusetts Institute Of Technology | Steroid modulators in the treatment of peripheral nerve sheath tumors |
| CA2605796A1 (en) * | 2005-04-25 | 2006-11-02 | Pfizer Products Inc. | Pharmaceutical compositions and methods comprising a combination of a selective estrogen receptor modulator and an aromatase inhibitor |
| US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
| GB0813628D0 (en) * | 2008-07-25 | 2008-09-03 | Arrow Int Ltd | Stable coated anti-cancer agent |
| WO2016153819A1 (en) | 2015-03-25 | 2016-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis using secondary ion mass spectrometry |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL350291A1 (en) * | 1998-12-23 | 2002-12-02 | Searle & Co | Method of using a cyclooxygenase-2 inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
-
2001
- 2001-08-21 AR ARP010103968A patent/AR034142A1/es not_active Application Discontinuation
- 2001-09-04 US US10/363,244 patent/US20040009962A1/en not_active Abandoned
- 2001-09-04 EP EP01966522A patent/EP1315483A2/en not_active Withdrawn
- 2001-09-04 JP JP2002524485A patent/JP2004508325A/ja not_active Withdrawn
- 2001-09-04 AU AU2001287028A patent/AU2001287028A1/en not_active Abandoned
- 2001-09-04 WO PCT/US2001/027308 patent/WO2002020000A2/en not_active Ceased
- 2001-09-06 PE PE2001000898A patent/PE20020466A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002020000A2 (en) | 2002-03-14 |
| AU2001287028A1 (en) | 2002-03-22 |
| JP2004508325A (ja) | 2004-03-18 |
| WO2002020000A3 (en) | 2003-02-27 |
| US20040009962A1 (en) | 2004-01-15 |
| EP1315483A2 (en) | 2003-06-04 |
| AR034142A1 (es) | 2004-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |