PE20011213A1 - Sales de imidazo-3-aminas e imidazo-5-aminas biciclicas n-aciladas y sus productos de adicion con acidos, procedimientos para su preparacion y medicamentos que contienen estos compuestos - Google Patents
Sales de imidazo-3-aminas e imidazo-5-aminas biciclicas n-aciladas y sus productos de adicion con acidos, procedimientos para su preparacion y medicamentos que contienen estos compuestosInfo
- Publication number
- PE20011213A1 PE20011213A1 PE2001000355A PE2001000355A PE20011213A1 PE 20011213 A1 PE20011213 A1 PE 20011213A1 PE 2001000355 A PE2001000355 A PE 2001000355A PE 2001000355 A PE2001000355 A PE 2001000355A PE 20011213 A1 PE20011213 A1 PE 20011213A1
- Authority
- PE
- Peru
- Prior art keywords
- imidazo
- alkyl
- amines
- phenyl
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 3
- -1 BUTYL Chemical group 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 206010013654 Drug abuse Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 241000347391 Umbrina cirrosa Species 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- ZHZZWIQPCAMTIM-UHFFFAOYSA-N [C]1=CC=CC2=CC=CC=C12 Chemical class [C]1=CC=CC2=CC=CC=C12 ZHZZWIQPCAMTIM-UHFFFAOYSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- QRZMXADUXZADTF-UHFFFAOYSA-N imidazo-5-amine Natural products NC1=CNC=N1 QRZMXADUXZADTF-UHFFFAOYSA-N 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
SE REFIERE A SALES DE IMIDAZO-3-AMINAS E IMIDAZO-5-AMINAS BICICLICAS, N-ACILADAS DE FORMULA I DONDE R1 ES BUTILO, 1,1,3,3-TETRAMETILBUTILO, (CH2)nCN, FENILO, CICLOALQUILO C4-C8, CH2CH2R, CH2Ra, ENTRE OTROS; n ES 4-6; R ES 4-MORFOLINO; Ra ES H, ALQUILO C1-C8, FENILO, ENTRE OTROS; R2 ES H, CORb; Rb ES ALQUILO C1-C8, ALCOXI C1-C8, ENTRE OTROS; R3 ES ALQUILO C1-C6, CICLOALQUILO C3-C8, FENILO, 1-NAFTILO, ENTRE OTROS; A ES UN GRUPO a, b, c, ENTRE OTROS; R4, R5, R6, R7 SON H, ALQUILO C1-C8, F, Cl, NHRf, ENTRE OTROS; Rf ES H, ALQUILO C1-C8, ENTRE OTROS; R8 ES ALQUILO C1-C8, ARILO, HETEROARILO, CICLOALQUILO C3-C8, ENTRE OTROS; X ES EL ANION DE UN ACIDO ORGANICO O INORGANICO. SON COMPUESTOS PREFERIDOS CLORURO DE 7-ACETIL-5-TER-BUTILAMINO-6-FENIL-IMIDAZO[2,1-b]-TIAZOLILO-7; CLORURO DE 1-ACETIL-8-BENCILOXI-3-TER-BUTILAMINO-2-METIL-IMIDAZO-[1,2-a]-PIRIDINIO-1, ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. LOS COMPUESTOS PUEDEN SER UTILES PARA TRATAR EL DOLOR, ABUSO DE DROGAS, ALCOHOL, DIARREA, GASTRITIS, ULCERAS , INCONTINENCIA URINARIA, DEPRESIONES, NARCOLEPSIA, ASMA, GLAUCOMA, PRURITO, SINDROME HIPERCINETICO, EPILEPSIA, ESQUIZOFRENIA, EFECTO ANESTESICO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10019714A DE10019714A1 (de) | 2000-04-20 | 2000-04-20 | Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20011213A1 true PE20011213A1 (es) | 2001-12-29 |
Family
ID=7639529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000355A PE20011213A1 (es) | 2000-04-20 | 2001-04-19 | Sales de imidazo-3-aminas e imidazo-5-aminas biciclicas n-aciladas y sus productos de adicion con acidos, procedimientos para su preparacion y medicamentos que contienen estos compuestos |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7087607B2 (es) |
| EP (1) | EP1274709B1 (es) |
| JP (1) | JP2003531208A (es) |
| KR (1) | KR100756594B1 (es) |
| CN (1) | CN1232520C (es) |
| AR (1) | AR030559A1 (es) |
| AT (1) | ATE277045T1 (es) |
| AU (2) | AU5830501A (es) |
| BR (1) | BR0110357A (es) |
| CA (1) | CA2402808A1 (es) |
| CZ (1) | CZ20023476A3 (es) |
| DE (2) | DE10019714A1 (es) |
| DK (1) | DK1274709T3 (es) |
| ES (1) | ES2227186T3 (es) |
| HK (1) | HK1052703B (es) |
| HU (1) | HUP0300532A3 (es) |
| IL (2) | IL152352A0 (es) |
| MX (1) | MXPA02009602A (es) |
| NO (1) | NO323542B1 (es) |
| NZ (1) | NZ521069A (es) |
| PE (1) | PE20011213A1 (es) |
| PL (1) | PL365676A1 (es) |
| PT (1) | PT1274709E (es) |
| RU (1) | RU2268888C2 (es) |
| SI (1) | SI1274709T1 (es) |
| SK (1) | SK15022002A3 (es) |
| TR (1) | TR200402755T4 (es) |
| UY (1) | UY26675A1 (es) |
| WO (1) | WO2001081344A1 (es) |
| ZA (1) | ZA200209408B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10019714A1 (de) | 2000-04-20 | 2002-01-10 | Gruenenthal Gmbh | Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen |
| DE10050663A1 (de) † | 2000-10-13 | 2002-04-18 | Gruenenthal Gmbh | Verwendung von substituierten Imidazo[1,2-a]pyridin-, -pyrimidin- und pyrazin-3-yl-amin-Derivaten zur Herstellung von Medikamenten zur NOS-Inhibierung |
| EP1902056A2 (en) | 2005-05-20 | 2008-03-26 | Array Biopharma, Inc. | Raf inhibitor compounds and methods of use thereof |
| US7709468B2 (en) | 2005-09-02 | 2010-05-04 | Abbott Laboratories | Imidazo based heterocycles |
| MX343042B (es) | 2005-12-23 | 2016-10-21 | Ariad Pharma Inc | Compuestos heteroarilicos biciclicos. |
| KR101449057B1 (ko) | 2006-03-17 | 2014-10-10 | 암비트 바이오사이언시즈 코포레이션 | 질환 치료용 이미다졸로티아졸 화합물 |
| DE602007006010D1 (de) * | 2006-05-31 | 2010-06-02 | Galapagos Nv | Triazolopyrazinverbindungen zur behandlung von degenerations- und entzündungskrankheiten |
| JP2010505855A (ja) * | 2006-10-06 | 2010-02-25 | アボット・ラボラトリーズ | 新規なイミダゾチアゾール類およびイミダゾオキサゾール類 |
| US8703492B2 (en) | 2007-04-06 | 2014-04-22 | Qiagen Gaithersburg, Inc. | Open platform hybrid manual-automated sample processing system |
| US7985375B2 (en) * | 2007-04-06 | 2011-07-26 | Qiagen Gaithersburg, Inc. | Sample preparation system and method for processing clinical specimens |
| KR20150104231A (ko) * | 2007-09-19 | 2015-09-14 | 암비트 바이오사이언시즈 코포레이션 | Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도 |
| WO2011063139A1 (en) | 2009-11-18 | 2011-05-26 | Qiagen | Laboratory central control unit method and system |
| KR200453430Y1 (ko) * | 2011-01-10 | 2011-05-03 | 백현숙 | 싱크대용 선반 |
| CN104583218B (zh) | 2012-04-26 | 2018-04-24 | 百时美施贵宝公司 | 作为蛋白酶活化受体4(par4)抑制剂用于治疗血小板聚集的咪唑并噻二唑和咪唑并吡嗪的衍生物 |
| CA2871599A1 (en) | 2012-04-26 | 2013-10-31 | Bristol-Myers Squibb Company | Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
| CN104540835B (zh) | 2012-04-26 | 2017-08-08 | 百时美施贵宝公司 | 用于治疗血小板聚集的作为蛋白酶激活受体4(par4)抑制剂的咪唑并噻二唑衍生物 |
| US9617279B1 (en) | 2014-06-24 | 2017-04-11 | Bristol-Myers Squibb Company | Imidazooxadiazole compounds |
| US9598419B1 (en) | 2014-06-24 | 2017-03-21 | Universite De Montreal | Imidazotriazine and imidazodiazine compounds |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2857776A (en) | 1955-01-13 | 1958-10-28 | American Metal Prod | Lead screw selectively operable and releasable under load |
| US3489755A (en) | 1966-08-03 | 1970-01-13 | Pfizer & Co C | Imidazo (1,2-b) pyridazines |
| US3792166A (en) * | 1970-11-16 | 1974-02-12 | American Cyanamid Co | Method of using substituted imidazo (2,1-b)thiazoles as anthelmintic agents |
| US3894022A (en) * | 1973-06-25 | 1975-07-08 | Sandoz Ag | Tetracyclic quinazolinones and quinazolinium salts |
| JPS5398997A (en) | 1977-02-09 | 1978-08-29 | Sumitomo Chem Co Ltd | Fused pyridine derivertives and process for their preparation |
| GB2039882A (en) * | 1979-01-05 | 1980-08-20 | Ciba Geigy Ag | Bicyclic thiadiaza compounds and their use as medicaments |
| DE3269604D1 (en) * | 1981-06-26 | 1986-04-10 | Schering Corp | Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them |
| FR2568880B1 (fr) * | 1984-08-07 | 1986-12-12 | Synthelabo | Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique |
| FR2627491B1 (fr) | 1988-02-18 | 1992-01-24 | Roussel Uclaf | Nouveaux derives du benzocyclohexane et du benzocycloheptane ainsi que leurs sels, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant |
| JPH0753730B2 (ja) * | 1988-07-26 | 1995-06-07 | 三共株式会社 | イミダゾピラゾール誘導体 |
| DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| IL108520A (en) * | 1993-02-15 | 1997-09-30 | Byk Gulden Lomberg Chem Fab | 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US5536853A (en) * | 1994-04-11 | 1996-07-16 | Chiron Corporation | Opiate receptor ligands |
| DE10019714A1 (de) | 2000-04-20 | 2002-01-10 | Gruenenthal Gmbh | Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen |
-
2000
- 2000-04-20 DE DE10019714A patent/DE10019714A1/de not_active Withdrawn
-
2001
- 2001-04-03 EP EP01931560A patent/EP1274709B1/de not_active Expired - Lifetime
- 2001-04-03 KR KR1020027014037A patent/KR100756594B1/ko not_active Expired - Fee Related
- 2001-04-03 AT AT01931560T patent/ATE277045T1/de active
- 2001-04-03 WO PCT/EP2001/003772 patent/WO2001081344A1/de not_active Ceased
- 2001-04-03 HU HU0300532A patent/HUP0300532A3/hu unknown
- 2001-04-03 SK SK1502-2002A patent/SK15022002A3/sk unknown
- 2001-04-03 TR TR2004/02755T patent/TR200402755T4/xx unknown
- 2001-04-03 DE DE50103764T patent/DE50103764D1/de not_active Expired - Lifetime
- 2001-04-03 NZ NZ521069A patent/NZ521069A/en unknown
- 2001-04-03 AU AU5830501A patent/AU5830501A/xx active Pending
- 2001-04-03 RU RU2002130245/04A patent/RU2268888C2/ru active
- 2001-04-03 PT PT01931560T patent/PT1274709E/pt unknown
- 2001-04-03 HK HK03105003.1A patent/HK1052703B/zh not_active IP Right Cessation
- 2001-04-03 IL IL15235201A patent/IL152352A0/xx unknown
- 2001-04-03 CA CA002402808A patent/CA2402808A1/en not_active Abandoned
- 2001-04-03 AU AU2001258305A patent/AU2001258305B2/en not_active Ceased
- 2001-04-03 BR BR0110357-1A patent/BR0110357A/pt not_active Application Discontinuation
- 2001-04-03 CN CNB018079423A patent/CN1232520C/zh not_active Expired - Fee Related
- 2001-04-03 JP JP2001578434A patent/JP2003531208A/ja not_active Withdrawn
- 2001-04-03 DK DK01931560T patent/DK1274709T3/da active
- 2001-04-03 PL PL01365676A patent/PL365676A1/xx not_active Application Discontinuation
- 2001-04-03 SI SI200130236T patent/SI1274709T1/xx unknown
- 2001-04-03 CZ CZ20023476A patent/CZ20023476A3/cs unknown
- 2001-04-03 ES ES01931560T patent/ES2227186T3/es not_active Expired - Lifetime
- 2001-04-03 MX MXPA02009602A patent/MXPA02009602A/es active IP Right Grant
- 2001-04-17 AR ARP010101796A patent/AR030559A1/es unknown
- 2001-04-19 PE PE2001000355A patent/PE20011213A1/es not_active Application Discontinuation
- 2001-04-20 UY UY26675A patent/UY26675A1/es not_active Application Discontinuation
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2002
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- 2002-10-18 US US10/273,344 patent/US7087607B2/en not_active Expired - Fee Related
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2006
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