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PE20010382A1 - Forma cristalina iii de la n-(4-(5-dimetilaminonaftalen-1-sulfonilamino)fenil)-3-hidroxi-2,2-dimetilpropionamida - Google Patents

Forma cristalina iii de la n-(4-(5-dimetilaminonaftalen-1-sulfonilamino)fenil)-3-hidroxi-2,2-dimetilpropionamida

Info

Publication number
PE20010382A1
PE20010382A1 PE2000000729A PE0007292000A PE20010382A1 PE 20010382 A1 PE20010382 A1 PE 20010382A1 PE 2000000729 A PE2000000729 A PE 2000000729A PE 0007292000 A PE0007292000 A PE 0007292000A PE 20010382 A1 PE20010382 A1 PE 20010382A1
Authority
PE
Peru
Prior art keywords
iii
dimethylaminonaphthalen
sulfonylamine
dimethylpropionamide
hydroxy
Prior art date
Application number
PE2000000729A
Other languages
English (en)
Inventor
Alfons Grunenberg
Andreas Lender
Andree Folkerts
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PE20010382A1 publication Critical patent/PE20010382A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A LA FORMA CRISTALINA III DE N-(4-(5-DIMETILAMINONAFTALEN-1-SULFONILAMINO)FENIL)-3-HIDROXI-2,2-DIMETILPROPIONAMIDA (DNSP) DE FORMULA I QUE SE CARACTERIZA POR: i)PUNTO DE FUSION DE 140°C, ii)VALORES DE DIFRACCION DE RAYOS X; iii)ESPECTRO RAMAN. SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA LA OBTENCION DE LA FORMA CRISTALINA III DE DNSP CARACTERIZADO PORQUE SE SUSPENDE LA FORMA CRISTALINA I DE DNSP EN AGUA Y/O DISOLVENTES ORGANICOS INERTES A TEMPERATURAS DE 0°C-60°C HASTA LA TRANSFORMACION CUANTITATIVA A LA FORMA CRISTALINA III. LA FORMA CRISTALINA III DE LA N-(4-(5-DIMETILAMINONAFTALEN-1-SULFONILAMINO)FENIL-3-HIDROXI-2,2-DIMETILPROPIONAMIDA PUEDE SER UTIL PARA EL TRATAMIENTO O PROFILAXIS DE ENFERMEDADES CAUSADAS POR CITOMEGALOVIRUS HUMANO (HCMV) EN PACIENTES CON SIDA, CON TRASPLANTES DE MEDULA Y ORGANOS, EN RECIEN NACIDOS Y NINOS PEQUENOS
PE2000000729A 1999-07-21 2000-07-20 Forma cristalina iii de la n-(4-(5-dimetilaminonaftalen-1-sulfonilamino)fenil)-3-hidroxi-2,2-dimetilpropionamida PE20010382A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19934295A DE19934295A1 (de) 1999-07-21 1999-07-21 Kristallmodifikation III von N-(4-(5-Dimethylamino-naphthalin-1-sulfonyl-amino)-phenyl)-3-hydroxy-2,2-dimethyl-propionamid

Publications (1)

Publication Number Publication Date
PE20010382A1 true PE20010382A1 (es) 2001-06-11

Family

ID=7915608

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000729A PE20010382A1 (es) 1999-07-21 2000-07-20 Forma cristalina iii de la n-(4-(5-dimetilaminonaftalen-1-sulfonilamino)fenil)-3-hidroxi-2,2-dimetilpropionamida

Country Status (8)

Country Link
AR (1) AR024797A1 (es)
AU (1) AU6562600A (es)
CO (1) CO5180571A1 (es)
DE (1) DE19934295A1 (es)
GT (1) GT200000114A (es)
PE (1) PE20010382A1 (es)
UY (1) UY26251A1 (es)
WO (1) WO2001007404A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780794B2 (en) 2000-01-20 2004-08-24 Honeywell International Inc. Methods of bonding physical vapor deposition target materials to backing plate materials
US6698647B1 (en) 2000-03-10 2004-03-02 Honeywell International Inc. Aluminum-comprising target/backing plate structures
US7371906B2 (en) * 2004-08-24 2008-05-13 Eastman Kodak Company Process for photo-oxidative stability improvements
EP2481540B1 (de) 2011-01-28 2017-11-01 Schelling Anlagenbau GmbH Einrichtung zum Zersägen von zumindest zwei platten- oder plattenstapelförmigen Werkstücken

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20000532A2 (en) * 1998-01-23 2001-02-28 Bayer Ag Novel naphthyl-substituted and anilide-substituted sulfonamides

Also Published As

Publication number Publication date
WO2001007404A1 (de) 2001-02-01
CO5180571A1 (es) 2002-07-30
DE19934295A1 (de) 2001-01-25
AR024797A1 (es) 2002-10-23
GT200000114A (es) 2002-01-01
UY26251A1 (es) 2001-01-31
AU6562600A (en) 2001-02-13

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