PE20010609A1 - Quitosana y metodo para la preparacion de quitosana - Google Patents
Quitosana y metodo para la preparacion de quitosanaInfo
- Publication number
- PE20010609A1 PE20010609A1 PE2000000746A PE0007462000A PE20010609A1 PE 20010609 A1 PE20010609 A1 PE 20010609A1 PE 2000000746 A PE2000000746 A PE 2000000746A PE 0007462000 A PE0007462000 A PE 0007462000A PE 20010609 A1 PE20010609 A1 PE 20010609A1
- Authority
- PE
- Peru
- Prior art keywords
- chitosane
- biomass
- chitosan
- chitin
- caustic solution
- Prior art date
Links
- 239000002028 Biomass Substances 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 229920002101 Chitin Polymers 0.000 abstract 3
- 229920001661 Chitosan Polymers 0.000 abstract 3
- 239000003518 caustics Substances 0.000 abstract 2
- 241000228245 Aspergillus niger Species 0.000 abstract 1
- 241001465318 Aspergillus terreus Species 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/917—Aspergillus niger
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/921—Candida
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
- Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Materials Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
EN DONDE LA QUITOSANA ES DERIVADO DE BIOMASA MICROBIANA TAL COMO CANDIDA GUILLERMONDII, ASPERGILLUS NIGER Y ASPERGILLUS TERREUS, Y TIENE MAS DE 85% DE DESACETILACION DE GRUPOS N-ACETILO EN LA QUITINA. EL METODO COMPRENDE: a) PROPORCIONAR BIOMASA CONTENIENDO QUITINA; b) REACCIONAR DICHA BIOMASA, EN UNA SOLUCION CAUSTICA DE MAS DE 25% ALCALI A UNA TEMPERATURA DE REACCION MAYOR A 95°C DURANTE POR LO MENOS 10 HORAS PARA CONVERTIR LA QUITINA A QUITOSANA; c) LAVAR LA BIOMASA DESACETILADA CON UNA SOLUCION CAUSTICA; d) RECUPERAR LA QUITOSANA; e) PRECIPITAR LA QUITOSANA; Y, f) SECAR LA QUITOSANA PRECIPITADA. ADEMAS, UNA SOLUCION DE 1% EN PESO DE UN MATERIAL CONTENIENDO QUITOSANA EN 1% DE ACIDO ACETICO ACUOSO TIENE UNA VISCOSIDAD MENOR DE 25 cPo A 25°C Y UNA TURBIDEZ MENOR DE 40 NTU
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18956000P | 2000-03-15 | 2000-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010609A1 true PE20010609A1 (es) | 2001-05-24 |
Family
ID=22697851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000746A PE20010609A1 (es) | 2000-03-15 | 2000-07-25 | Quitosana y metodo para la preparacion de quitosana |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6972284B2 (es) |
| EP (1) | EP1272528B1 (es) |
| KR (1) | KR20010091847A (es) |
| AR (1) | AR024921A1 (es) |
| AU (1) | AU2000266079A1 (es) |
| BR (1) | BR0003114A (es) |
| CA (1) | CA2313836C (es) |
| MX (1) | MXPA02009042A (es) |
| PE (1) | PE20010609A1 (es) |
| WO (1) | WO2001068714A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| NO20015986D0 (no) | 2001-08-02 | 2001-12-06 | Einar J Mustaparta | Produktet chitosan, samt fremstillingsmetode og anvendelse av chitosan |
| IS6085A (is) * | 2001-09-26 | 2003-03-27 | Genis Ehf. | Lyfjablanda með kítósan óligómerum |
| KR100451399B1 (ko) * | 2001-11-02 | 2004-10-06 | 주식회사 건풍바이오 | 키토산의 아세틸화 방법 |
| BE1014638A6 (fr) | 2002-02-12 | 2004-02-03 | Univ Liege | Methode de preparation de derives de la paroi cellulaire a partir de biomasse. |
| AU2003221828A1 (en) * | 2002-04-02 | 2003-10-27 | Cargill, Inc. | Chitosan production |
| CA2501820C (en) * | 2002-10-08 | 2009-12-15 | Ricom Corporation | Chitosan-containing polysaccharide, method for preparing the same and use thereof |
| US7544785B2 (en) * | 2003-06-06 | 2009-06-09 | Venture Chemicals, Inc. | Process for the treatment for chitinaceous materials and for the deacetylation of chitin |
| WO2005118952A1 (en) * | 2004-06-01 | 2005-12-15 | Pulp And Paper Research Institute Of Canada | Papermaking additive |
| CA2586587C (en) * | 2004-11-25 | 2011-01-04 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Method of determining tropomyosin in chitosan |
| US20070088157A1 (en) * | 2005-10-17 | 2007-04-19 | Hubbs John C | Preparation of glucosamine |
| US20090022799A1 (en) * | 2006-10-06 | 2009-01-22 | Shikha Pramanik Barman | Compositions that contain beta-glucan to be used for the prevention and treatment of disease and methods for their use |
| US20080188649A1 (en) * | 2007-02-01 | 2008-08-07 | Hygieia Health Co., Ltd. | Method for producing glucosamine from microbial biomass |
| EP3075842A1 (en) * | 2009-12-23 | 2016-10-05 | Agrinos AS | Biodegradation process and composition |
| CA2788017A1 (en) * | 2010-02-01 | 2011-08-04 | Fpinnovations | Fungal modified chitosan adhesives and wood composites made from the adhesives |
| WO2011097566A1 (en) * | 2010-02-08 | 2011-08-11 | Renewable Process Technologies Llc | System and method for producing biomaterials |
| CN101832938B (zh) | 2010-04-29 | 2012-11-07 | 山东华兴纺织集团有限公司 | 一种用于测定纺织品中壳聚糖纤维含量的方法 |
| FR2981075A1 (fr) | 2011-10-11 | 2013-04-12 | Kitozyme | Procede de preparation de glucans a partir d'aspergillus niger |
| WO2013131079A1 (en) * | 2012-03-02 | 2013-09-06 | President And Fellows Of Harvard College | Fabrication of 3-d articles with chitosan |
| US9249235B2 (en) | 2013-03-15 | 2016-02-02 | Johannes van Leeuwen | Processes for isolating chitin and chitosan from fungal biomass |
| GB201309788D0 (en) * | 2013-05-31 | 2013-07-17 | Medtrade Products Ltd | Process for the removal of contamination from a raw material |
| CN107320767A (zh) * | 2017-06-05 | 2017-11-07 | 浙江工业大学 | 一种含n‑糖基化壳聚糖的快速成膜流体敷料及其制备与应用 |
| CN112424234A (zh) * | 2018-06-08 | 2021-02-26 | 麦基托科学公司 | 制备壳聚糖的方法 |
| WO2021136882A1 (en) * | 2019-12-30 | 2021-07-08 | Kemira Oyj | Animal free chitosan and methods and uses related thereto |
| EP4138791A1 (en) | 2020-04-20 | 2023-03-01 | Board of Regents, The University of Texas System | Biologically active dry powder compositions and method of their manufacture and use |
| KR102574114B1 (ko) * | 2021-02-17 | 2023-09-04 | 한국화학연구원 | 아세틸화된 키토산 마이크로 입자의 제조방법 및 이로부터 제조된 아세틸화된 키토산 마이크로 입자. |
| BE1030387B1 (fr) * | 2022-03-24 | 2023-10-24 | Kitozyme S A | Procédé de production de chitosane à partir de mycélium fongique |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB458839A (en) | 1934-06-21 | 1936-12-21 | Du Pont | Chitin compounds |
| US2040879A (en) * | 1934-06-21 | 1936-05-19 | Du Pont | Substantially undegraded deacetylated chitin and process for producing the same |
| US3232836A (en) * | 1959-08-24 | 1966-02-01 | Pfizer & Co C | Facilitating healing of body surface wounds by intravenous administration of n-acetyl glucosamine, glucosamine, or pharmaceutically acceptable acid salts of glucosamine |
| US3903268A (en) * | 1968-02-12 | 1975-09-02 | Lescarden Ltd | Chitin and chitin derivatives for promoting wound healing |
| US3632754A (en) * | 1968-02-12 | 1972-01-04 | Lescarden Ltd | Use of chitin for promoting wound healing |
| US3911116A (en) * | 1970-04-13 | 1975-10-07 | Leslie L Balassa | Process for promoting wound healing with chitin derivatives |
| US3914413A (en) * | 1971-02-10 | 1975-10-21 | Leslie L Balassa | Process for facilitating wound healing with N-acetylated partially depolymerized chitin materials |
| US4056432A (en) | 1971-07-06 | 1977-11-01 | Calgon Corporation | Process for making paper products of improved dry strength |
| IT1104351B (it) | 1978-06-14 | 1985-10-21 | Muzzarelli Riccardo | Il complesso glucano chitosano il metodo della sua produzione a partire da muffe funghi e lieviti e i suoi usi |
| JPS58441B2 (ja) * | 1978-07-08 | 1983-01-06 | 工業技術院長 | キトサンの製造方法 |
| US4948881A (en) | 1982-12-28 | 1990-08-14 | Sanofi | Process for the depolymerization and sulfation of polysaccharides |
| US4886541A (en) | 1984-10-05 | 1989-12-12 | Washington State University Research Foundation | Method for treating cereal crop seed with chitosan to enhance yield, root growth and stem strength |
| US4806474A (en) | 1985-06-10 | 1989-02-21 | Miles Inc. | Preparation of mycelial chitosan and glucan fractions from microbial biomass |
| JPS6270401A (ja) | 1985-09-24 | 1987-03-31 | Fuji Boseki Kk | カルボキシアルキルキトサン粒状体の製造方法 |
| JPS6397633A (ja) | 1986-10-13 | 1988-04-28 | Fuji Boseki Kk | 新規なキトサン粒状物 |
| JPS63225602A (ja) | 1987-03-13 | 1988-09-20 | Nitta Zerachin Kk | 易溶性キトサン |
| JPH0220292A (ja) | 1988-07-06 | 1990-01-23 | Agency Of Ind Science & Technol | 低分子化キトサンの製造方法 |
| JPH02135134A (ja) * | 1988-11-16 | 1990-05-24 | Katokichi:Kk | 水・アルコール混合液分離用膜 |
| JPH02149335A (ja) | 1988-11-30 | 1990-06-07 | Nippon Oil & Fats Co Ltd | キトサン・ゼラチン架橋ゲル |
| JPH02180903A (ja) | 1988-12-29 | 1990-07-13 | Nippon Oil & Fats Co Ltd | 架橋キトサン |
| JP2732107B2 (ja) | 1989-01-31 | 1998-03-25 | 日本化薬株式会社 | 低分子量キトサンの製造方法 |
| JPH075741B2 (ja) | 1989-03-03 | 1995-01-25 | 富士紡績株式会社 | スルホン基を有する粒状多孔質キトサン誘導体の製造方法 |
| JPH02258740A (ja) | 1989-03-31 | 1990-10-19 | Taiyo Kagaku Kogyo Kk | キトサンに安息香酸を吸着させる方法 |
| US5262310A (en) * | 1991-05-31 | 1993-11-16 | Akebono Brake Industry Co, Ltd. | Enzymatic decomposition method of chitin-containing materials |
| JPH05199892A (ja) | 1991-09-11 | 1993-08-10 | Shin Etsu Chem Co Ltd | キトサンの製造方法 |
| JP3181337B2 (ja) | 1991-09-13 | 2001-07-03 | ピアス株式会社 | キトサンオリゴ糖混合物の製造方法、及びキチンオリゴ糖混合物の製造方法 |
| US5219749A (en) | 1991-10-09 | 1993-06-15 | Institute For Molecular Biology & Biotechnology/Forth | Process for isolating and preparing purified chitin deacetylase |
| JP2905093B2 (ja) | 1994-06-03 | 1999-06-14 | 大日精化工業株式会社 | キトサンの希硫酸水溶液及びその製造方法 |
| JP2901176B2 (ja) * | 1994-07-27 | 1999-06-07 | 日本化薬株式会社 | 低粘度キトサン及びその製造方法 |
| US5792647A (en) | 1995-02-13 | 1998-08-11 | The Johns Hopkins University | Bacterial catabolism of chitin |
| US6333399B1 (en) * | 1995-02-13 | 2001-12-25 | Alexander Teslenko | Process for producing chitosan-glucan complexes, compounds producible therefrom and their use |
| US5998173A (en) * | 1996-02-20 | 1999-12-07 | The University Of Bristish Columbia | Process for producing N-acetyl-D-glucosamine |
| EP0957925B1 (en) * | 1996-12-13 | 2005-04-20 | Lescarden, Inc. | Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine |
| US6372457B1 (en) | 1997-01-14 | 2002-04-16 | Arkion Life Sciences Llc | Process and materials for production of glucosamine |
| GB9706195D0 (en) | 1997-03-25 | 1997-05-14 | Univ London Pharmacy | Particulate drug carriers |
| US5905035A (en) * | 1997-04-15 | 1999-05-18 | Asahi Kasei Kogyo Kabushiki Kaisha | Fungus useful for chitin production |
| JP4213773B2 (ja) | 1997-04-23 | 2009-01-21 | 川研ファインケミカル株式会社 | 界面活性剤の脱臭脱色方法 |
| US5730876A (en) | 1997-05-30 | 1998-03-24 | Hyang-Ja You | Separation and purification of low molecular weight chitosan using multi-step membrane separation process |
| EP0885954A1 (en) | 1997-06-16 | 1998-12-23 | Societe Des Produits Nestle S.A. | Chitinolytic enzymes production by Penicillium janthinellum |
| AU2003221828A1 (en) * | 2002-04-02 | 2003-10-27 | Cargill, Inc. | Chitosan production |
-
2000
- 2000-07-11 CA CA002313836A patent/CA2313836C/en not_active Expired - Lifetime
- 2000-07-24 AR ARP000103807A patent/AR024921A1/es not_active Application Discontinuation
- 2000-07-24 KR KR1020000042436A patent/KR20010091847A/ko not_active Withdrawn
- 2000-07-24 BR BR0003114-3A patent/BR0003114A/pt not_active Application Discontinuation
- 2000-07-25 PE PE2000000746A patent/PE20010609A1/es not_active Application Discontinuation
- 2000-07-25 MX MXPA02009042A patent/MXPA02009042A/es unknown
- 2000-07-25 EP EP00953667A patent/EP1272528B1/en not_active Expired - Lifetime
- 2000-07-25 AU AU2000266079A patent/AU2000266079A1/en not_active Abandoned
- 2000-07-25 WO PCT/US2000/020173 patent/WO2001068714A1/en not_active Ceased
- 2000-12-18 US US09/739,406 patent/US6972284B2/en not_active Expired - Lifetime
-
2005
- 2005-06-15 US US11/153,801 patent/US7413881B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2313836A1 (en) | 2001-09-15 |
| CA2313836C (en) | 2009-06-09 |
| US20020025945A1 (en) | 2002-02-28 |
| BR0003114A (pt) | 2001-12-04 |
| KR20010091847A (ko) | 2001-10-23 |
| MXPA02009042A (es) | 2003-04-25 |
| EP1272528B1 (en) | 2012-08-22 |
| AU2000266079A1 (en) | 2001-09-24 |
| US20050245482A1 (en) | 2005-11-03 |
| US7413881B2 (en) | 2008-08-19 |
| US6972284B2 (en) | 2005-12-06 |
| EP1272528A1 (en) | 2003-01-08 |
| AR024921A1 (es) | 2002-10-30 |
| WO2001068714A1 (en) | 2001-09-20 |
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