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PE20001365A1 - Dispositivo de suministro de farmacos, especialmente para el suministro de androgenos - Google Patents

Dispositivo de suministro de farmacos, especialmente para el suministro de androgenos

Info

Publication number
PE20001365A1
PE20001365A1 PE1999001234A PE00123499A PE20001365A1 PE 20001365 A1 PE20001365 A1 PE 20001365A1 PE 1999001234 A PE1999001234 A PE 1999001234A PE 00123499 A PE00123499 A PE 00123499A PE 20001365 A1 PE20001365 A1 PE 20001365A1
Authority
PE
Peru
Prior art keywords
siloxane
androgen
trifluoropropyl
silicon
methyl
Prior art date
Application number
PE1999001234A
Other languages
English (en)
Inventor
Jarkko Ruohonen
Matti Lehtinen
Harri Jukarainen
Tommi Markkula
Juha Ala-Sorvari
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of PE20001365A1 publication Critical patent/PE20001365A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

SE REFIERE A UN DISPOSITIVO DE SUMINISTRO PARA LA LIBERACION CONTROLADA DE UN ANDROGENO TAL COMO 17-O-METIL-19-NORTESTOSTERONA O ACETATO DE 7-O-METIL-19-NORTESTOSTERONA, QUE COMPRENDE EL NUCLEO EN EL QUE SE ENCUENTRA EL ANDROGENO; UNA MEMBRANA QUE INCLUYE EN SU INTERIOR UN NUCLEO ELABORADA A BASE DE UN ELASTOMERO DE SILOXANO, DE 1% A 50% DE 3,3,3,-TRIFLUOROPROPILO UNIDOS AL SILICIO DEL SILOXANO SIENDO DE PREFERENCIA i)UNA MEZCLA DE UN POLIMERO BASADO EN SILOXANO (POLI(DIMETILSILOXANO)) OPCIONALMENTE EN EL QUE EL AL MENOS EL 50% DE METILO UNIDO A SILICIO HAN SIDO SUSTITUIDOS CON 3,3,3-TRIFLUOROPROPILO) NO SUSTITUIDO CON F, UN POLIMERO BASADO EN SILOXANO SUSTITUIDO CON F; b)UN UNICO POLIMERO BASADO EN SILOXANO QUE COMPRENDE 3,3,3-TRIFLUOROPROPILO UNIDOS AL SILICIO DEL SILOXANO, LA MEZCLA Y EL POLIMERO SON RETICULADOS PARA FORMAR EL ELASTOMERO; SIENDO EL DISPOSITIVO IMPLANTABLE DESTINADO A LA ADMINISTRACION SUBCUTANEA
PE1999001234A 1998-11-12 1999-12-10 Dispositivo de suministro de farmacos, especialmente para el suministro de androgenos PE20001365A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/190,607 US6117442A (en) 1998-11-12 1998-11-12 Drug delivery device, especially for the delivery of androgens

Publications (1)

Publication Number Publication Date
PE20001365A1 true PE20001365A1 (es) 2000-12-09

Family

ID=22702035

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999001234A PE20001365A1 (es) 1998-11-12 1999-12-10 Dispositivo de suministro de farmacos, especialmente para el suministro de androgenos

Country Status (30)

Country Link
US (1) US6117442A (es)
EP (1) EP1128810B1 (es)
JP (1) JP2003521456A (es)
KR (1) KR20010075699A (es)
CN (1) CN1367682A (es)
AR (1) AR021153A1 (es)
AT (1) ATE241338T1 (es)
AU (1) AU769229B2 (es)
BG (1) BG65009B1 (es)
BR (1) BR9915327A (es)
CA (1) CA2351064A1 (es)
CO (1) CO5170475A1 (es)
CZ (1) CZ301089B6 (es)
DE (1) DE69908399T2 (es)
DK (1) DK1128810T3 (es)
EE (1) EE05415B1 (es)
ES (1) ES2201794T3 (es)
HK (1) HK1048769A1 (es)
HU (1) HU228191B1 (es)
ID (1) ID29339A (es)
IL (2) IL142524A0 (es)
NO (1) NO20012046L (es)
NZ (1) NZ511214A (es)
PE (1) PE20001365A1 (es)
PL (1) PL194873B1 (es)
PT (1) PT1128810E (es)
RU (1) RU2226388C2 (es)
SK (1) SK285073B6 (es)
WO (1) WO2000028967A1 (es)
ZA (1) ZA200103299B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063395A (en) * 1998-11-12 2000-05-16 Leiras Oy Drug delivery device especially for the delivery of progestins and estrogens
US6299894B1 (en) * 2000-05-10 2001-10-09 Leiras Oy Drug delivery device, especially for the delivery of gestodene
AU2001258442A1 (en) * 2000-05-10 2001-11-20 Leiras Oy Drug delivery device, especially for the delivery of levonorgestrel
AU2002313517B2 (en) * 2001-08-31 2007-09-06 Bayer Schering Pharma Oy Drug delivery system
EP1438942A1 (en) * 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
WO2006078320A2 (en) 2004-08-04 2006-07-27 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
BRPI0617325B8 (pt) 2005-10-13 2021-06-22 Synthes Gmbh luva biologicamente compatível
JP5502751B2 (ja) 2007-12-20 2014-05-28 エボニック コーポレイション 低残留溶媒濃度を有する微粒子を調製するためのプロセス
EP2476409A1 (en) * 2011-01-14 2012-07-18 Université Catholique De Louvain Implant comprising a core and a tube encasing the core
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
USD718435S1 (en) 2012-05-30 2014-11-25 Medicines360 Intrauterine insertion device
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
PE20211195A1 (es) * 2017-09-27 2021-07-01 Bayer Oy Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomerica
US11571328B2 (en) 2018-04-09 2023-02-07 Medicines360 IUD insertion devices
US20200261258A1 (en) 2019-02-19 2020-08-20 Medicines360 Devices, systems, methods and kits for insertion and removal of iuds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
IT8702928A0 (it) * 1987-07-22 1987-07-22 Alga Di Giudici Angelamaria & Friggitrice con cestello rotante secondo un asse orizzontale.
ES2054784T3 (es) * 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
DK0525049T3 (es) * 1990-04-02 1997-03-17 Procter & Gamble
JPH07216233A (ja) * 1992-09-21 1995-08-15 Toray Dow Corning Silicone Co Ltd フルオロシリコーンゴム組成物
US5733565A (en) * 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant

Also Published As

Publication number Publication date
AU769229B2 (en) 2004-01-22
PL356658A1 (en) 2004-06-28
US6117442A (en) 2000-09-12
AR021153A1 (es) 2002-06-12
IL142524A (en) 2006-12-31
IL142524A0 (en) 2002-03-10
HUP0202666A2 (hu) 2002-12-28
NZ511214A (en) 2003-04-29
ID29339A (id) 2001-08-23
BG105500A (en) 2001-12-29
BR9915327A (pt) 2001-10-09
ES2201794T3 (es) 2004-03-16
DE69908399T2 (de) 2004-02-05
CN1367682A (zh) 2002-09-04
EE05415B1 (et) 2011-06-15
ATE241338T1 (de) 2003-06-15
DK1128810T3 (da) 2003-09-15
HUP0202666A3 (en) 2008-10-28
AU1048700A (en) 2000-06-05
NO20012046D0 (no) 2001-04-26
HK1048769A1 (zh) 2003-04-17
EP1128810B1 (en) 2003-05-28
HU228191B1 (hu) 2013-01-28
CO5170475A1 (es) 2002-06-27
DE69908399D1 (de) 2003-07-03
SK285073B6 (sk) 2006-05-04
JP2003521456A (ja) 2003-07-15
RU2226388C2 (ru) 2004-04-10
EE200100255A (et) 2002-12-16
WO2000028967A1 (en) 2000-05-25
ZA200103299B (en) 2002-05-13
BG65009B1 (bg) 2006-12-29
EP1128810A1 (en) 2001-09-05
KR20010075699A (ko) 2001-08-09
CZ301089B6 (cs) 2009-11-04
PT1128810E (pt) 2003-09-30
CZ20011571A3 (cs) 2001-09-12
NO20012046L (no) 2001-06-28
SK5152001A3 (en) 2001-10-08
PL194873B1 (pl) 2007-07-31
CA2351064A1 (en) 2000-05-25

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed