PE20000346A1 - Administracion de un agente activo en aerosol - Google Patents
Administracion de un agente activo en aerosolInfo
- Publication number
- PE20000346A1 PE20000346A1 PE1999000202A PE00020299A PE20000346A1 PE 20000346 A1 PE20000346 A1 PE 20000346A1 PE 1999000202 A PE1999000202 A PE 1999000202A PE 00020299 A PE00020299 A PE 00020299A PE 20000346 A1 PE20000346 A1 PE 20000346A1
- Authority
- PE
- Peru
- Prior art keywords
- hormone
- bormeron
- active agent
- refers
- interferon
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 title abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102100022712 Alpha-1-antitrypsin Human genes 0.000 abstract 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 abstract 1
- 102000055006 Calcitonin Human genes 0.000 abstract 1
- 108060001064 Calcitonin Proteins 0.000 abstract 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 abstract 1
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 102000009151 Luteinizing Hormone Human genes 0.000 abstract 1
- 108010073521 Luteinizing Hormone Proteins 0.000 abstract 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 101710142969 Somatoliberin Proteins 0.000 abstract 1
- 102000005157 Somatostatin Human genes 0.000 abstract 1
- 108010056088 Somatostatin Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 abstract 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 abstract 1
- 229960004436 budesonide Drugs 0.000 abstract 1
- 229960004015 calcitonin Drugs 0.000 abstract 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 229930182912 cyclosporin Natural products 0.000 abstract 1
- 229960004222 factor ix Drugs 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 230000003325 follicular Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000003434 inspiratory effect Effects 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 239000003055 low molecular weight heparin Substances 0.000 abstract 1
- 229940127215 low-molecular weight heparin Drugs 0.000 abstract 1
- 229940040129 luteinizing hormone Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000199 parathyroid hormone Substances 0.000 abstract 1
- 229960001319 parathyroid hormone Drugs 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
- 229960000553 somatostatin Drugs 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION EN AEROSOL CON UN INDICE DE FLUJO INSPIRATORIO INFERIOR A 17 LITROS POR MINUTO QUE COMPRENDE UN AGENTE ACTIVO EN FORMA DE POLVO SECO, NEBULIZACION, SOLUCION, SUSPENSION, QUE OPCIONALMENTE ESTA MEZCLADO CON UN IMPELENTE. EL AGENTE ACTIVO PUEDE SER CICLOSPORINA, HORMONA PARATIROIDEA, HORMONA FOLICULO ESTIMULANTE, ANTITRIPSINA ALFA-1, BUDESONIDA, HORMONA DEL CRECIMIENTO HUMANO, HORMONA LIBERADORA DE LA HORMONA DEL CRECIMIENTO, INTERFERON ALFA, INTERFERON BETA, FACTOR ESTIMULANTE DE COLONIAS DEL CRECIMIENTO, HORMONA LIBERADORA DE LA HORMONA LUTEINIZANTE, CALCITONINA, HEPARINA DE BAJO PESO MOLECULAR, SOMATOSTATINA, ANTICUERPO DEL VIRUS SINCITIAL RESPIRATORIO, ERITROPOYETINA, FACTOR VIII, FACTOR IX, CEREDASA, CEREZIMA, INSULINA. TAMBIEN SE REFIERE A UN DISPOSITIVO QUE PRESENTA UN REGULADOR DE FLUJO CON ABERTURAS DE 0,5 mm A 0,9 mm DE DIAMETRO EN EL CUAL EL REGULADOR DE FLUJO CONSISTE EN UNA VALVULA
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7821298P | 1998-03-16 | 1998-03-16 | |
| US7821498P | 1998-03-16 | 1998-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000346A1 true PE20000346A1 (es) | 2000-04-12 |
Family
ID=26760240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000202A PE20000346A1 (es) | 1998-03-16 | 1999-03-15 | Administracion de un agente activo en aerosol |
Country Status (42)
| Country | Link |
|---|---|
| US (2) | US6655379B2 (es) |
| EP (1) | EP1066074A1 (es) |
| JP (1) | JP4195191B2 (es) |
| KR (1) | KR100620338B1 (es) |
| CN (1) | CN1292714B (es) |
| AP (1) | AP1342A (es) |
| AR (1) | AR018161A1 (es) |
| AU (1) | AU750539B2 (es) |
| BG (1) | BG65091B1 (es) |
| BR (1) | BR9908771A (es) |
| CA (1) | CA2322045C (es) |
| CO (1) | CO5060522A1 (es) |
| DZ (1) | DZ2744A1 (es) |
| EA (1) | EA003196B1 (es) |
| EE (1) | EE200000546A (es) |
| GE (1) | GEP20043260B (es) |
| HN (1) | HN1999000028A (es) |
| HR (2) | HRP20000608A2 (es) |
| HU (1) | HUP0100848A3 (es) |
| ID (1) | ID26237A (es) |
| IL (1) | IL138153A0 (es) |
| IS (1) | IS5595A (es) |
| LT (1) | LT4818B (es) |
| LV (1) | LV12586B (es) |
| MA (1) | MA26033A1 (es) |
| MY (1) | MY131803A (es) |
| NO (1) | NO20004627L (es) |
| NZ (1) | NZ506289A (es) |
| OA (1) | OA11529A (es) |
| PA (1) | PA8468901A1 (es) |
| PE (1) | PE20000346A1 (es) |
| PL (1) | PL343276A1 (es) |
| RO (1) | RO121834B1 (es) |
| SA (1) | SA99200198B1 (es) |
| SI (1) | SI20413A (es) |
| SK (1) | SK13632000A3 (es) |
| TN (1) | TNSN99038A1 (es) |
| TR (1) | TR200002692T2 (es) |
| TW (1) | TWI228998B (es) |
| UY (1) | UY25432A1 (es) |
| WO (1) | WO1999047196A1 (es) |
| YU (1) | YU56600A (es) |
Families Citing this family (136)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU688283B2 (en) | 1992-09-29 | 1998-03-12 | Novartis Ag | Pulmonary delivery of active fragments of parathyroid hormone |
| EP2036541A1 (en) | 1994-03-07 | 2009-03-18 | Nektar Therapeutics | Methods and compositions for pulmonary delivery of insulin |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US6309671B1 (en) * | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| GB9807232D0 (en) * | 1998-04-03 | 1998-06-03 | Univ Cardiff | Aerosol composition |
| UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| JP4711520B2 (ja) * | 2000-03-21 | 2011-06-29 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| DK1280520T4 (en) | 2000-05-10 | 2018-06-25 | Novartis Ag | Phospholipid based powders for drug delivery |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| CN100551358C (zh) * | 2000-06-27 | 2009-10-21 | 维克多瑞有限公司 | 用于药物组合物的颗粒的制备方法 |
| US6339107B1 (en) | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
| EP1935869A1 (en) | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
| US7049283B2 (en) | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
| US6782887B2 (en) * | 2001-01-12 | 2004-08-31 | Becton, Dickinson And Company | Medicament respiratory delivery device and cartridge |
| ES2431634T3 (es) | 2001-06-20 | 2013-11-27 | Novartis Ag | Dispositivo de administración de aerosol |
| GB2380946A (en) * | 2001-08-31 | 2003-04-23 | Medic Aid Ltd | Nebuliser arrangement |
| SI1458360T1 (sl) | 2001-12-19 | 2011-08-31 | Novartis Ag | Pulmonalno dajanje aminoglikozidov |
| PT1494732E (pt) | 2002-03-20 | 2008-03-20 | Mannkind Corp | Aparelho de inalação |
| US7814900B2 (en) | 2002-03-22 | 2010-10-19 | Clinical Designs Limited | Can fixture |
| UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| US7185651B2 (en) | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
| AU2003303036A1 (en) * | 2002-12-13 | 2004-07-09 | Pfizer Products Inc. | Method of decreasing hepatic glucose output in diabetic patients |
| US20050236296A1 (en) * | 2002-12-30 | 2005-10-27 | Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) | Carry case for aerosolization apparatus |
| GB0304000D0 (en) | 2003-02-21 | 2003-03-26 | Clinical Designs Ltd | Dispenser |
| KR101066788B1 (ko) * | 2003-04-09 | 2011-09-21 | 노바르티스 아게 | 공기 입구 차폐 부재를 갖춘 에어로졸화 장치 |
| ES2887054T3 (es) | 2003-04-11 | 2021-12-21 | Ptc Therapeutics Inc | Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades |
| GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
| DE60325906D1 (de) | 2003-08-08 | 2009-03-05 | Amgen Fremont Inc | Antikörper gegen parath-hormon (pth) und ihre verwendungen |
| US7318925B2 (en) * | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
| NZ547689A (en) | 2003-11-19 | 2009-05-31 | Signal Pharm Llc | Indazole compounds and methods of use thereof as protein kinase inhibitors |
| GB0327112D0 (en) | 2003-11-21 | 2003-12-24 | Clincial Designs Ltd | Dispenser and reservoir |
| GB0328859D0 (en) | 2003-12-12 | 2004-01-14 | Clinical Designs Ltd | Dispenser and counter |
| WO2005065756A2 (en) | 2003-12-30 | 2005-07-21 | Oriel Therapeutics, Inc. | Dry powder nebulizers and associated methods of dispensing dry powders |
| MX2007001903A (es) | 2004-08-20 | 2007-08-02 | Mannkind Corp | Catalisis de sintesis de dicetopiperazina. |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| EP1791555B1 (en) * | 2004-09-10 | 2013-03-13 | Pharmaorigin ApS | Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis |
| GB0425518D0 (en) | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
| US7827983B2 (en) * | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
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| AU2006272922A1 (en) | 2005-07-22 | 2007-02-01 | Amgen Inc. | Aniline sulfonamide derivatives and their uses |
| GB0518400D0 (en) | 2005-09-09 | 2005-10-19 | Clinical Designs Ltd | Dispenser |
| KR101486397B1 (ko) | 2005-09-14 | 2015-01-28 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
| DK1981572T3 (da) * | 2006-02-09 | 2013-03-04 | Pari Pharma Gmbh | Pulmonal afgivelse af alfa-1-proteinaseinhibitor |
| BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
| AU2007259143A1 (en) | 2006-06-08 | 2007-12-21 | Amgen Inc. | Benzamide derivatives and uses related thereto |
| TW200808695A (en) | 2006-06-08 | 2008-02-16 | Amgen Inc | Benzamide derivatives and uses related thereto |
| AU2007275301A1 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1 |
| EP2121580A2 (en) | 2006-12-26 | 2009-11-25 | Amgen Inc. | N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases |
| US8991402B2 (en) | 2007-12-18 | 2015-03-31 | Pax Labs, Inc. | Aerosol devices and methods for inhaling a substance and uses thereof |
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| ES2242289T3 (es) * | 1997-07-25 | 2005-11-01 | MINNESOTA INNOVATIVE TECHNOLOGIES & INSTRUMENTS CORPORATION (MITI) | Dispositivo de control para suministrar oxigeno suplementario para respiracion. |
| CA2212430A1 (en) | 1997-08-07 | 1999-02-07 | George Volgyesi | Inhalation device |
| US5855202A (en) | 1997-10-08 | 1999-01-05 | Andrade; Joseph R. | Aerosol holding chamber for a metered-dose inhaler |
| US6067984A (en) * | 1997-10-14 | 2000-05-30 | Piper; Samuel David | Pulmonary modulator apparatus |
| US6032667A (en) * | 1997-10-30 | 2000-03-07 | Instrumentarium Corporation | Variable orifice pulse valve |
| US6116238A (en) | 1997-12-02 | 2000-09-12 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US6076523A (en) * | 1998-01-15 | 2000-06-20 | Nellcor Puritan Bennett | Oxygen blending in a piston ventilator |
| US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
-
1999
- 1999-03-11 GE GEAP19995591A patent/GEP20043260B/en unknown
- 1999-03-11 WO PCT/US1999/004654 patent/WO1999047196A1/en not_active Ceased
- 1999-03-11 KR KR1020007010232A patent/KR100620338B1/ko not_active Expired - Fee Related
- 1999-03-11 CN CN998037133A patent/CN1292714B/zh not_active Expired - Fee Related
- 1999-03-11 ID IDW20001760A patent/ID26237A/id unknown
- 1999-03-11 NZ NZ50628999A patent/NZ506289A/xx unknown
- 1999-03-11 SI SI9920017A patent/SI20413A/sl not_active IP Right Cessation
- 1999-03-11 TR TR2000/02692T patent/TR200002692T2/xx unknown
- 1999-03-11 AP APAP/P/2000/001902A patent/AP1342A/en active
- 1999-03-11 BR BR9908771-5A patent/BR9908771A/pt not_active Application Discontinuation
- 1999-03-11 IL IL13815399A patent/IL138153A0/xx not_active IP Right Cessation
- 1999-03-11 HR HR20000608A patent/HRP20000608A2/hr not_active Application Discontinuation
- 1999-03-11 LT LT2000095A patent/LT4818B/lt not_active IP Right Cessation
- 1999-03-11 CA CA002322045A patent/CA2322045C/en not_active Expired - Fee Related
- 1999-03-11 SK SK1363-2000A patent/SK13632000A3/sk unknown
- 1999-03-11 HU HU0100848A patent/HUP0100848A3/hu unknown
- 1999-03-11 RO ROA200000909A patent/RO121834B1/ro unknown
- 1999-03-11 PL PL99343276A patent/PL343276A1/xx not_active Application Discontinuation
- 1999-03-11 EA EA200000823A patent/EA003196B1/ru not_active IP Right Cessation
- 1999-03-11 AU AU29803/99A patent/AU750539B2/en not_active Ceased
- 1999-03-11 EE EEP200000546A patent/EE200000546A/xx unknown
- 1999-03-11 YU YU56600A patent/YU56600A/sh unknown
- 1999-03-11 JP JP2000536435A patent/JP4195191B2/ja not_active Expired - Fee Related
- 1999-03-11 OA OA1200000236A patent/OA11529A/en unknown
- 1999-03-11 EP EP99911071A patent/EP1066074A1/en not_active Withdrawn
- 1999-03-11 US US09/266,720 patent/US6655379B2/en not_active Expired - Lifetime
- 1999-03-15 MA MA25495A patent/MA26033A1/fr unknown
- 1999-03-15 MY MYPI99000957A patent/MY131803A/en unknown
- 1999-03-15 UY UY25432A patent/UY25432A1/es not_active Application Discontinuation
- 1999-03-15 AR ARP990101116A patent/AR018161A1/es unknown
- 1999-03-15 TW TW088103965A patent/TWI228998B/zh not_active IP Right Cessation
- 1999-03-15 DZ DZ990045A patent/DZ2744A1/xx active
- 1999-03-15 PE PE1999000202A patent/PE20000346A1/es not_active Application Discontinuation
- 1999-03-15 TN TNTNSN99038A patent/TNSN99038A1/fr unknown
- 1999-03-16 PA PA19998468901A patent/PA8468901A1/es unknown
- 1999-03-16 HR HR60/078,214A patent/HRP990081A2/hr not_active Application Discontinuation
- 1999-03-16 HN HN1999000028A patent/HN1999000028A/es unknown
- 1999-03-16 CO CO99016181A patent/CO5060522A1/es unknown
- 1999-05-31 SA SA99200198A patent/SA99200198B1/ar unknown
-
2000
- 2000-08-22 IS IS5595A patent/IS5595A/is unknown
- 2000-08-28 BG BG104720A patent/BG65091B1/bg unknown
- 2000-09-15 NO NO20004627A patent/NO20004627L/no not_active Application Discontinuation
- 2000-09-22 LV LVP-00-129A patent/LV12586B/en unknown
-
2003
- 2003-07-25 US US10/627,591 patent/US20050090798A1/en not_active Abandoned
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