PE16198A1 - Compuesto de ciclohexapeptidil bis-amina, composiciones que lo contienen y metodos de uso - Google Patents
Compuesto de ciclohexapeptidil bis-amina, composiciones que lo contienen y metodos de usoInfo
- Publication number
- PE16198A1 PE16198A1 PE1996000784A PE00078496A PE16198A1 PE 16198 A1 PE16198 A1 PE 16198A1 PE 1996000784 A PE1996000784 A PE 1996000784A PE 00078496 A PE00078496 A PE 00078496A PE 16198 A1 PE16198 A1 PE 16198A1
- Authority
- PE
- Peru
- Prior art keywords
- cyclohexapeptidil
- bis
- methods
- compositions containing
- amine compound
- Prior art date
Links
- -1 BIS-AMINE COMPOUND Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000228212 Aspergillus Species 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 241000233872 Pneumocystis carinii Species 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- DTQVDTLACAAQTR-UHFFFAOYSA-M Trifluoroacetate Chemical compound [O-]C(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE AL HEXAPEPTIDO DE FORMULA (I) O SU SAL DE ADICION, CARACTERIZADO POR UN GRUPO NAFTOILO SUSTITUIDO CON OC7H15 EN LA UNIDAD PEPTIDICA 5-AMINOETIL-OXI-4-HIDROXIORNITINA, EN DONDE TAL SAL DE ADICION DE ACIDO SE SELECCIONE DE: ACETATO, TRIFLUOROACETATO, CLORURO, BROMURO, TARTRATO, SUCCINATO, GLUTAMATO, SULFATO, FOSFATO O PAMOATO. ES UTIL PARA TRATAR INFECCIONES FUNGICAS CAUSADAS POR CANDIDA O ASPERGILLUS E INFECCIONES CAUSADAS POR PNEUMOCYSTIS CARINII
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US650595P | 1995-11-09 | 1995-11-09 | |
| GBGB9603241.2A GB9603241D0 (en) | 1996-02-16 | 1996-02-16 | Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE16198A1 true PE16198A1 (es) | 1998-04-11 |
Family
ID=26308720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1996000784A PE16198A1 (es) | 1995-11-09 | 1996-11-07 | Compuesto de ciclohexapeptidil bis-amina, composiciones que lo contienen y metodos de uso |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0862579A1 (es) |
| JP (1) | JP2000501076A (es) |
| AR (1) | AR001314A1 (es) |
| AU (1) | AU707664B2 (es) |
| CA (1) | CA2235824A1 (es) |
| CO (1) | CO4770984A1 (es) |
| HR (1) | HRP960521A2 (es) |
| PE (1) | PE16198A1 (es) |
| WO (1) | WO1997017365A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002532513A (ja) * | 1998-12-16 | 2002-10-02 | イーライ リリー アンド カンパニー | 糖置換基を有する環式ペプチド抗真菌剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030944A (en) * | 1991-10-01 | 2000-02-29 | Merck & Co., Inc. | Cyclohexapeptidyl bisamine compounds |
| US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
| AU681119B2 (en) * | 1993-05-17 | 1997-08-21 | Fujisawa Pharmaceutical Co., Ltd. | New polypeptide compound and a process for preparation thereof |
-
1996
- 1996-11-06 WO PCT/US1996/017715 patent/WO1997017365A1/en not_active Ceased
- 1996-11-06 JP JP9518271A patent/JP2000501076A/ja active Pending
- 1996-11-06 EP EP96937905A patent/EP0862579A1/en not_active Ceased
- 1996-11-06 AU AU75540/96A patent/AU707664B2/en not_active Ceased
- 1996-11-06 CA CA002235824A patent/CA2235824A1/en not_active Abandoned
- 1996-11-07 PE PE1996000784A patent/PE16198A1/es not_active Application Discontinuation
- 1996-11-07 HR HR9603241.2A patent/HRP960521A2/hr not_active Application Discontinuation
- 1996-11-07 CO CO96058746A patent/CO4770984A1/es unknown
- 1996-11-08 AR ARP960105124 patent/AR001314A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO4770984A1 (es) | 1999-04-30 |
| AR001314A1 (es) | 1997-10-22 |
| CA2235824A1 (en) | 1997-05-15 |
| WO1997017365A1 (en) | 1997-05-15 |
| AU7554096A (en) | 1997-05-29 |
| JP2000501076A (ja) | 2000-02-02 |
| AU707664B2 (en) | 1999-07-15 |
| HRP960521A2 (en) | 1998-04-30 |
| EP0862579A1 (en) | 1998-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |