PE118999A1 - COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS - Google Patents
COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERSInfo
- Publication number
- PE118999A1 PE118999A1 PE1998000885A PE00088598A PE118999A1 PE 118999 A1 PE118999 A1 PE 118999A1 PE 1998000885 A PE1998000885 A PE 1998000885A PE 00088598 A PE00088598 A PE 00088598A PE 118999 A1 PE118999 A1 PE 118999A1
- Authority
- PE
- Peru
- Prior art keywords
- compositions
- methods
- respiratory disorders
- treating respiratory
- hydroxydiphenylmethyl
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000023504 respiratory system disease Diseases 0.000 title 1
- MITFXPHMIHQXPI-UHFFFAOYSA-N Oraflex Chemical compound N=1C2=CC(C(C(O)=O)C)=CC=C2OC=1C1=CC=C(Cl)C=C1 MITFXPHMIHQXPI-UHFFFAOYSA-N 0.000 abstract 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
- SYTBZMRGLBWNTM-JTQLQIEISA-N (S)-flurbiprofen Chemical compound FC1=CC([C@@H](C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-JTQLQIEISA-N 0.000 abstract 1
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 abstract 1
- 206010028735 Nasal congestion Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 229960005430 benoxaprofen Drugs 0.000 abstract 1
- 229960001948 caffeine Drugs 0.000 abstract 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 abstract 1
- -1 cetirizine Chemical compound 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 229960002390 flurbiprofen Drugs 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
CARACTERIZADO PORQUE COMPRENDE a)UN ANALGESICO TAL COMO NAPROXENO O EL ENANTIOMERO S(+)-QUETOPROFENO, LISINATO, S(+)-IBUPROFENO; b)UN ANTIHISTAMINICO TAL COMO CETIRIZINA, METILO-4-[1-HIDROXIDIFENILMETILO-1-PIPERIDINILO)BUTILO]-O,O-DIMETILBENZINOACETATO, ACIDO 4-[1-HIDROXI-4-(4-HIDROXIDIFENILMETILO-1-PIPERIDINILO)BUTILO]-O,O-DIMETILBENZINOACETICO, ENTRE OTROS. LA COMPOSICION PUEDE COMPRENDER ADEMAS a)OTRO AGENTE ANALGESICO TAL COMO IBUPROFENO , BENOXAPROFENO, FLURBIPROFENO, ENTRE OTROS; b)UN DESCONGESTIONANTE; c)UN EXPECTORANTE; d)UN ANTITUSIVO; e)UN COMPUESTO AGONISTA-O, CAFEINA. LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO DE LA TOS, RESFRIADO, SINTOMAS PARECIDOS AL RESFRIADO, CONGESTION NASAL, SINUSITIS, DOLORCHARACTERIZED BECAUSE IT INCLUDES a) AN ANALGESIC SUCH AS NAPROXENO OR THE ENANTIOMER S (+) - QUETOPROFENO, LISINATO, S (+) - IBUPROFENO; b) an antihistamine such as cetirizine, methyl-4- [1-hydroxydiphenylmethyl-1-piperidinyl) BUTYL] -O, O-DIMETILBENZINOACETATO, 4- [1-hydroxy-4- (4-hydroxydiphenylmethyl-1-piperidinyl) BUTYL ] -O, O-DIMETILBENZINOACETICO, AMONG OTHERS. THE COMPOSITION MAY FURTHER INCLUDE a) ANOTHER ANALGESIC AGENT SUCH AS IBUPROFEN, BENOXAPROFEN, FLURBIPROFEN, AMONG OTHERS; b) A DISCOUNTER; c) AN EXPECTORANT; d) AN ANTI-TUSSIVE; e) AN AGONIST-O COMPOUND, CAFFEINE. THE COMPOSITION MAY BE USEFUL FOR THE TREATMENT OF COUGH, COLD, SYMPTOMS SIMILAR TO COLD, NASAL CONGESTION, SINUSITIS, PAIN
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93403397A | 1997-09-19 | 1997-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE118999A1 true PE118999A1 (en) | 2000-02-03 |
Family
ID=25464848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000885A PE118999A1 (en) | 1997-09-19 | 1998-09-17 | COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1014983A1 (en) |
| JP (1) | JP2001517626A (en) |
| KR (1) | KR20010024187A (en) |
| CN (1) | CN1278728A (en) |
| AU (1) | AU8744398A (en) |
| BR (1) | BR9812660A (en) |
| CA (1) | CA2304005A1 (en) |
| CO (1) | CO5011084A1 (en) |
| HU (1) | HUP0004813A2 (en) |
| NO (1) | NO20001412D0 (en) |
| PE (1) | PE118999A1 (en) |
| WO (1) | WO1999015173A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2419653A1 (en) * | 2000-09-08 | 2002-03-14 | Warner-Lambert Company | Prevention of acute sinusitis and sinus attack |
| EP1401444A1 (en) * | 2001-06-20 | 2004-03-31 | Schering Corporation | Antihistamines for the treatment of nasal congestion and nasal obstruction |
| US6863901B2 (en) | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
| US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
| US7166641B2 (en) * | 2002-10-02 | 2007-01-23 | Yung Shin Pharmaceutical Industrial Co., Ltd. | Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same |
| TWI313598B (en) | 2002-12-18 | 2009-08-21 | Wyeth Corp | Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines |
| FR2865648B1 (en) * | 2004-02-03 | 2006-06-30 | Philippe Perovitch | METHOD FOR DIFFUSION OF INSOLUBLE MOLECULES IN AQUEOUS MEDIUM AND COMPOSITION IMPLEMENTING SAID METHOD |
| US20050192355A1 (en) * | 2004-02-17 | 2005-09-01 | Wyeth | Compositions of non-steroidal anti-inflammatory drugs and decongestants or anti-histamines |
| CN101073563B (en) * | 2007-02-07 | 2010-10-06 | 西安利君制药有限责任公司 | A kind of chiral composition containing dexibuprofen and levocetirizine and its slow and rapid release bilayer tablet |
| GB0719518D0 (en) * | 2007-10-05 | 2007-11-14 | Therapeutics Ltd E | Therapy |
| US8246988B2 (en) | 2009-01-05 | 2012-08-21 | Mcneil-Ppc, Inc. | Three layer tablet containing cetirizine, pseudoephedrine, and naproxen |
| US8377475B2 (en) | 2009-01-05 | 2013-02-19 | Mcneil-Ppc, Inc. | Tablet containing cetirizine, pseudoephedrine, and naproxen containing a barrier layer |
| CA2750196C (en) * | 2009-01-05 | 2017-06-20 | Mcneil-Ppc, Inc. | Tablet containing coated particles of cetirizine, pseudoephedrine, and/or naproxen |
| GB0905954D0 (en) * | 2009-04-06 | 2009-05-20 | E Therapeutics Plc | Treatment of exacerbations of asthma |
| CN103446587A (en) * | 2011-12-28 | 2013-12-18 | 汪明 | Application of mastocyte inhibitor in preparation of medicine for resisting influenza virus infection |
| CN103251590B (en) * | 2013-05-13 | 2014-12-17 | 中国科学院武汉病毒研究所 | Application of doxylamine succinate in preparing drug for treating or preventing influenza virus |
| AU2016235484B2 (en) * | 2015-03-26 | 2021-02-18 | Jacqueline M. Iversen | Methods and compositions to inhibit symptoms associated with veisalgia |
| CN109464670B (en) * | 2017-09-08 | 2022-08-02 | 中国科学院微生物研究所 | Key amino acid site for regulating and controlling nucleoprotein nuclear production of influenza A virus and influenza B virus and application of key amino acid site as anti-influenza virus drug target |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4871733A (en) * | 1984-04-09 | 1989-10-03 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| US4783465A (en) * | 1984-04-09 | 1988-11-08 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| US5260073A (en) * | 1990-05-21 | 1993-11-09 | Norwich Eaton Pharmaceuticals, Inc. | Use of phenylpropanolamine as a mucus secretogogue in the upper airways |
| EP0719156A1 (en) * | 1993-09-07 | 1996-07-03 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| EP0841947A1 (en) * | 1995-07-28 | 1998-05-20 | The Procter & Gamble Company | Compositions containing analgesics and antihistamines and methods for treating respiratory disorders |
| US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
-
1998
- 1998-08-28 CA CA002304005A patent/CA2304005A1/en not_active Abandoned
- 1998-08-28 WO PCT/IB1998/001339 patent/WO1999015173A1/en not_active Ceased
- 1998-08-28 HU HU0004813A patent/HUP0004813A2/en unknown
- 1998-08-28 KR KR1020007002958A patent/KR20010024187A/en not_active Withdrawn
- 1998-08-28 JP JP2000512542A patent/JP2001517626A/en not_active Withdrawn
- 1998-08-28 EP EP98938852A patent/EP1014983A1/en not_active Withdrawn
- 1998-08-28 CN CN98811202A patent/CN1278728A/en active Pending
- 1998-08-28 AU AU87443/98A patent/AU8744398A/en not_active Abandoned
- 1998-08-28 BR BR9812660-1A patent/BR9812660A/en not_active Application Discontinuation
- 1998-09-17 PE PE1998000885A patent/PE118999A1/en not_active Application Discontinuation
- 1998-09-21 CO CO98054352A patent/CO5011084A1/en unknown
-
2000
- 2000-03-17 NO NO20001412A patent/NO20001412D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9812660A (en) | 2000-08-22 |
| AU8744398A (en) | 1999-04-12 |
| KR20010024187A (en) | 2001-03-26 |
| CN1278728A (en) | 2001-01-03 |
| EP1014983A1 (en) | 2000-07-05 |
| NO20001412D0 (en) | 2000-03-17 |
| CA2304005A1 (en) | 1999-04-01 |
| CO5011084A1 (en) | 2001-02-28 |
| JP2001517626A (en) | 2001-10-09 |
| HUP0004813A2 (en) | 2001-08-28 |
| WO1999015173A1 (en) | 1999-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |