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BR9809022A - Topical nasal anti-inflammatory compositions - Google Patents

Topical nasal anti-inflammatory compositions

Info

Publication number
BR9809022A
BR9809022A BR9809022-4A BR9809022A BR9809022A BR 9809022 A BR9809022 A BR 9809022A BR 9809022 A BR9809022 A BR 9809022A BR 9809022 A BR9809022 A BR 9809022A
Authority
BR
Brazil
Prior art keywords
nasal
agent
compositions
effective amount
therapeutically effective
Prior art date
Application number
BR9809022-4A
Other languages
Portuguese (pt)
Inventor
Catherine A Segal
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BR9809022A publication Critical patent/BR9809022A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES ANTIINFLAMATóRIAS NASAIS TóPICAS"<D>. A presente invenção proporciona composições nasais topicamente aplicáveis compreendendo uma quantidade terapeuticamente eficaz de um agente antiinflamatório e uma quantidade terapeuticamente eficaz de pelo menos um agente selecionado do grupo consistindo de um vasoconstritor,um inibidor neuramidinase um inibidor leucotrieno, um anti-histamínico, um agente antialérgico, um agente anticolinérgico, um anestésico e um agente mucolítico. As presentes composições são úteis como sprays nasais e gotas nasais para o tratamento de condições nasais e de sinus.Invention Patent: <B> "TOPICAL NASAL ANTIINFLAMMATORY COMPOSITIONS" <D>. The present invention provides topically applicable nasal compositions comprising a therapeutically effective amount of an anti-inflammatory agent and a therapeutically effective amount of at least one agent selected from the group consisting of a vasoconstrictor, a neuramidinase inhibitor, a leukotriene inhibitor, an antihistamine, an antiallergic agent , an anticholinergic agent, an anesthetic and a mucolytic agent. The present compositions are useful as nasal sprays and nasal drops for the treatment of sinus and nasal conditions.

BR9809022-4A 1997-04-30 1998-04-02 Topical nasal anti-inflammatory compositions BR9809022A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4430697P 1997-04-30 1997-04-30
PCT/US1998/006483 WO1998048839A1 (en) 1997-04-30 1998-04-02 Topical nasal antiinflammatory compositions

Publications (1)

Publication Number Publication Date
BR9809022A true BR9809022A (en) 2000-08-01

Family

ID=21931638

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809022-4A BR9809022A (en) 1997-04-30 1998-04-02 Topical nasal anti-inflammatory compositions

Country Status (8)

Country Link
EP (1) EP0979105A1 (en)
JP (1) JP2001524108A (en)
CN (1) CN1253508A (en)
AU (1) AU6878098A (en)
BR (1) BR9809022A (en)
CA (1) CA2281789A1 (en)
IL (1) IL131492A0 (en)
WO (1) WO1998048839A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ295461B6 (en) * 1997-08-26 2005-08-17 Aventis Pharmaceuticals Inc. Pharmaceutical preparation in the form of bilayer tablet
HUP0101369A3 (en) * 1997-12-23 2002-11-28 Schering Corp Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine
US6384038B1 (en) * 1998-04-14 2002-05-07 Sepracor Inc. Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
IT1313567B1 (en) * 1999-07-27 2002-09-09 Zambon Spa USE OF N-ACETYL-CISTEIN FOR THE PREPARATION OF TOPICAL PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ALLERGIC PATHOLOGIES OF
DE10007203A1 (en) 2000-02-17 2001-08-23 Asta Medica Ag Composition for treating allergic and/or vasomotor rhinitis or allergic conjunctivitis by topical or oral administration, contains synergistic combination of non-sedating antihistamine and leukotriene antagonist
ATE318601T1 (en) * 2001-09-18 2006-03-15 Nycomed Danmark Aps COMPOSITIONS FOR THE TREATMENT OF RUNNING WHICH CONTAIN IPRATROPIUM AND XYLOMETAZOLINE
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
JP2005533076A (en) * 2002-06-20 2005-11-04 ノバルテイス・コンシユーマー・ヘルス・エス・アー Nasal composition comprising mucopolysaccharide and propylene glycol
MXPA05001885A (en) 2002-08-30 2005-06-03 Altana Pharma Ag The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis.
DK1658063T3 (en) * 2003-08-06 2014-05-12 Galephar M F BENEFICIAL COMBINATIONS FOR INHALATION OF NACYSTLINE AND SOURCE CODILATORS
US20050255154A1 (en) 2004-05-11 2005-11-17 Lena Pereswetoff-Morath Method and composition for treating rhinitis
ES2704482T3 (en) 2004-11-24 2019-03-18 Meda Pharmaceuticals Inc Compositions comprising azelastine and its methods of use
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
PL1863476T3 (en) * 2005-03-16 2016-07-29 Meda Pharma Gmbh & Co Kg The combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases
CN101247800B (en) * 2005-08-26 2011-04-27 明治乳业株式会社 Antiallergic
AU2007272970C1 (en) 2006-07-11 2013-01-10 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
JP2008143845A (en) * 2006-12-11 2008-06-26 Hoshienu Seiyaku Kk Nasal drop composition and nasal drop spraying tool
CN104334164A (en) * 2012-05-25 2015-02-04 埃克斯可利尔公司 Xylitol-based anti-mucosal compositions and related methods and compositions
CN104667256B (en) * 2015-03-18 2017-05-03 江苏威克斯医疗科技有限公司 Nasal cavity mucosa cilium nursing flushing fluid and application thereof
CN107753485A (en) * 2017-11-28 2018-03-06 赵永宏 A kind of pharmaceutical composition for having nose congestion and anesthetic effect concurrently and its application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3482015A (en) * 1965-02-08 1969-12-02 Merck & Co Inc Aerosol composition of phenylephrine tartrate and the production of such
US4053628A (en) * 1971-05-12 1977-10-11 Fisons Limited Composition
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
JPH0753671B2 (en) * 1985-12-26 1995-06-07 積水化学工業株式会社 Transdermal / transmucosal preparation
ES2137981T3 (en) * 1991-11-19 2000-01-01 Univ Virginia COMBINED TREATMENT BY ANTIMEDIATIC AND ANTIVIRIC AGENTS OF COMMON COLDS.
AU7604094A (en) * 1993-09-07 1995-03-27 Procter & Gamble Company, The Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
AU6392496A (en) * 1995-06-29 1997-01-30 Mcneil-Ppc, Inc. The combination of topical nasal antihistamines and topical nasal steroids
AU6290396A (en) * 1995-06-29 1997-01-30 Mcneil-Ppc, Inc. The combination of topical nasal mast cell stabilizers and topical nasal steroids
DE19532714A1 (en) * 1995-09-05 1997-03-06 Bayer Ag Combination of 5-lipoxygenase and leukotriene synthesis inhibitors with glucocorticosteroids
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine

Also Published As

Publication number Publication date
CN1253508A (en) 2000-05-17
IL131492A0 (en) 2001-01-28
JP2001524108A (en) 2001-11-27
CA2281789A1 (en) 1998-11-05
EP0979105A1 (en) 2000-02-16
AU6878098A (en) 1998-11-24
WO1998048839A1 (en) 1998-11-05

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/57 (2006.01), A61K 31/58 (2006.0