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LV10437A - Aizvietoti 1-(1H-imidazol-4-il)alkil-benzamidi - Google Patents

Aizvietoti 1-(1H-imidazol-4-il)alkil-benzamidi

Info

Publication number
LV10437A
LV10437A LV930548A LV930548A LV10437A LV 10437 A LV10437 A LV 10437A LV 930548 A LV930548 A LV 930548A LV 930548 A LV930548 A LV 930548A LV 10437 A LV10437 A LV 10437A
Authority
LV
Latvia
Prior art keywords
alkyl
imidazol
hydrogen
compounds
hydroxyl
Prior art date
Application number
LV930548A
Other languages
English (en)
Other versions
LV10437B (en
Inventor
Eric Cossement
Jean-Pierre Geerts
Jean Gobert
Philippe Michel
Ernst Wuelfert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of LV10437A publication Critical patent/LV10437A/lv
Publication of LV10437B publication Critical patent/LV10437B/lv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
LVP-93-548A 1988-04-28 1993-06-11 Substituted 1-(1h-imidazole-4-yl)alkylbenzamides LV10437B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888810067A GB8810067D0 (en) 1988-04-28 1988-04-28 Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides

Publications (2)

Publication Number Publication Date
LV10437A true LV10437A (lv) 1995-02-20
LV10437B LV10437B (en) 1996-04-20

Family

ID=10636026

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-548A LV10437B (en) 1988-04-28 1993-06-11 Substituted 1-(1h-imidazole-4-yl)alkylbenzamides

Country Status (30)

Country Link
US (1) US4923865A (lv)
EP (1) EP0341231B1 (lv)
JP (1) JP2840288B2 (lv)
KR (1) KR970011275B1 (lv)
AT (1) ATE82571T1 (lv)
AU (1) AU610796B2 (lv)
BR (2) BR1100052A (lv)
CA (1) CA1310966C (lv)
CY (1) CY1758A (lv)
DE (1) DE68903531T2 (lv)
DK (1) DK205589A (lv)
ES (1) ES2052969T3 (lv)
FI (1) FI101791B1 (lv)
GB (1) GB8810067D0 (lv)
GR (1) GR3006836T3 (lv)
HK (1) HK9494A (lv)
HU (1) HU203877B (lv)
IE (1) IE63698B1 (lv)
IL (1) IL90087A0 (lv)
LT (1) LT3671B (lv)
LV (1) LV10437B (lv)
MY (1) MY104084A (lv)
NO (1) NO173331C (lv)
NZ (1) NZ228897A (lv)
PH (1) PH25461A (lv)
PL (2) PL156250B1 (lv)
PT (1) PT90368B (lv)
RU (3) RU1830063C (lv)
UA (1) UA12835A1 (lv)
ZA (1) ZA893140B (lv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310965D0 (en) * 1993-05-27 1993-07-14 Ucb Sa 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
HUT74386A (en) * 1993-11-15 1996-12-30 Schering Corp Phenyl-alkyl imidazoles as h3-receptor antagonists and pharmaceutical compositions containing them
JP3294961B2 (ja) * 1993-12-10 2002-06-24 杏林製薬株式会社 新規イミダゾール誘導体及びその製造法
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
DE10161818A1 (de) * 2001-12-14 2003-06-26 Gruenenthal Gmbh Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
BRPI0516132A (pt) * 2004-10-07 2007-12-04 Vitae Pharmaceuticals Inc compostos, composição destes, método de antagonização de uma ou mais proteases aspárticas e método para tratar ou melhorar um distúrbio mediado por protease aspártica
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
EP2167609A1 (en) * 2007-06-20 2010-03-31 Vitae Pharmaceuticals, Inc. Renin inhibitors
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
US20090226549A1 (en) 2008-03-06 2009-09-10 Kenneth John Hughes Herbal extracts and flavor systems for oral products and methods of making the same
US20110160300A1 (en) * 2008-06-20 2011-06-30 Marlys Hammond Renin Inhibitors and Methods of Use Thereof
CN102088850A (zh) * 2008-06-26 2011-06-08 生命医药公司 甲基2-((r)-(3-氯苯基)((r)-1-((s)-2-(甲氨基)-3((r)-四氢-2h-吡喃-3-基)丙基氨甲酰基)哌啶-3-基)甲氧基)氨基甲酸乙酯的盐
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
US9249087B2 (en) * 2011-02-01 2016-02-02 The Board Of Trustees Of The University Of Illinois HDAC inhibitors and therapeutic methods using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
US4303485A (en) 1979-08-20 1981-12-01 Minnesota Mining And Manufacturing Company Ultraviolet polymerization of acrylate monomers using oxidizable tin compounds
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
DE3635700A1 (de) 1986-10-21 1988-04-28 Michael Schmeller Hubeinrichtung
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds

Also Published As

Publication number Publication date
IE63698B1 (en) 1995-05-31
FI891975A7 (fi) 1989-10-29
CY1758A (en) 1994-07-15
RU1814647C (ru) 1993-05-07
HUT51257A (en) 1990-04-28
HK9494A (en) 1994-02-09
FI101791B (fi) 1998-08-31
EP0341231B1 (fr) 1992-11-19
DE68903531D1 (de) 1992-12-24
NO891760D0 (no) 1989-04-27
AU610796B2 (en) 1991-05-23
EP0341231A1 (fr) 1989-11-08
BR1100064A (pt) 1999-12-07
LTIP827A (en) 1995-02-27
NO173331B (no) 1993-08-23
MY104084A (en) 1993-11-30
HU203877B (en) 1991-10-28
GR3006836T3 (lv) 1993-06-30
PH25461A (en) 1991-07-01
FI891975A0 (fi) 1989-04-26
PT90368B (pt) 1994-08-31
JP2840288B2 (ja) 1998-12-24
ES2052969T3 (es) 1994-07-16
FI101791B1 (fi) 1998-08-31
IL90087A0 (en) 1989-12-15
BR1100052A (pt) 1999-12-07
PT90368A (pt) 1989-11-10
IE891360L (en) 1989-10-28
DK205589A (da) 1989-10-29
ZA893140B (en) 1990-01-31
KR970011275B1 (ko) 1997-07-09
PL156250B1 (pl) 1992-02-28
UA12835A1 (uk) 1997-02-28
RU1836353C (ru) 1993-08-23
NO173331C (no) 1993-12-08
NZ228897A (en) 1990-08-28
AU3373089A (en) 1989-11-02
DE68903531T2 (de) 1993-04-29
ATE82571T1 (de) 1992-12-15
JPH01313467A (ja) 1989-12-18
CA1310966C (en) 1992-12-01
US4923865A (en) 1990-05-08
RU1830063C (ru) 1993-07-23
KR890016017A (ko) 1989-11-28
LV10437B (en) 1996-04-20
NO891760L (no) 1989-10-30
PL161362B1 (pl) 1993-06-30
DK205589D0 (da) 1989-04-27
GB8810067D0 (en) 1988-06-02
LT3671B (en) 1996-01-25

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