FI891975A7 - Substituerade 1-(1h-imidazol-4-yl)-alkyl-bensamider. - Google Patents

Substituerade 1-(1h-imidazol-4-yl)-alkyl-bensamider.

Info

Publication number: FI891975A7
Authority: FI; Finland
Prior art keywords: bensamider; substituerade; imidazol; alkyl
Prior art date: 1988-04-28

Application number

FI891975A

Other languages

English (en)

Other versions

FI891975A0 (fi

FI101791B (fi

FI101791B1 (fi

Inventor

Eric Cossement

Jean-Pierre Geerts

Jean Gobert

Philippe Michel

Ernst Wuelfert

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-28

Filing date

1989-04-26

Publication date

1989-10-29

1989-04-26 Application filed by Ucb Sa filed Critical Ucb Sa

1989-04-26 Publication of FI891975A0 publication Critical patent/FI891975A0/fi

1989-10-29 Publication of FI891975A7 publication Critical patent/FI891975A7/fi

1998-08-31 Application granted granted Critical

1998-08-31 Publication of FI101791B publication Critical patent/FI101791B/fi

1998-08-31 Publication of FI101791B1 publication Critical patent/FI101791B1/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Adhesives Or Adhesive Processes (AREA)
Lubricants (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyrrole Compounds (AREA)

FI891975A 1988-04-28 1989-04-26 Menetelmä valmistaa terapeuttisesti aktiivista substituoitua 1-(1H-imidatsol-4-yyli)alkyylibentsamidia FI101791B1 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8810067		1988-04-28
GB888810067A GB8810067D0 (en)	1988-04-28	1988-04-28	Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides

Publications (4)

Publication Number	Publication Date
FI891975A0 FI891975A0 (fi)	1989-04-26
FI891975A7 true FI891975A7 (fi)	1989-10-29
FI101791B FI101791B (fi)	1998-08-31
FI101791B1 FI101791B1 (fi)	1998-08-31

Family

ID=10636026

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI891975A FI101791B1 (fi)	1988-04-28	1989-04-26	Menetelmä valmistaa terapeuttisesti aktiivista substituoitua 1-(1H-imidatsol-4-yyli)alkyylibentsamidia

Country Status (30)

Country	Link
US (1)	US4923865A (fi)
EP (1)	EP0341231B1 (fi)
JP (1)	JP2840288B2 (fi)
KR (1)	KR970011275B1 (fi)
AT (1)	ATE82571T1 (fi)
AU (1)	AU610796B2 (fi)
BR (2)	BR1100052A (fi)
CA (1)	CA1310966C (fi)
CY (1)	CY1758A (fi)
DE (1)	DE68903531T2 (fi)
DK (1)	DK205589A (fi)
ES (1)	ES2052969T3 (fi)
FI (1)	FI101791B1 (fi)
GB (1)	GB8810067D0 (fi)
GR (1)	GR3006836T3 (fi)
HK (1)	HK9494A (fi)
HU (1)	HU203877B (fi)
IE (1)	IE63698B1 (fi)
IL (1)	IL90087A0 (fi)
LT (1)	LT3671B (fi)
LV (1)	LV10437B (fi)
MY (1)	MY104084A (fi)
NO (1)	NO173331C (fi)
NZ (1)	NZ228897A (fi)
PH (1)	PH25461A (fi)
PL (2)	PL156250B1 (fi)
PT (1)	PT90368B (fi)
RU (3)	RU1830063C (fi)
UA (1)	UA12835A1 (fi)
ZA (1)	ZA893140B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9310965D0 (en) *	1993-05-27	1993-07-14	Ucb Sa	2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
DE69432263T2 (de) *	1993-11-15	2003-12-04	Schering Corp., Kenilworth	Phenylalkyl-imidazole als h3-rezeptor-antagonisten
JP3294961B2 (ja) *	1993-12-10	2002-06-24	杏林製薬株式会社	新規イミダゾール誘導体及びその製造法
GB9521680D0 (en) *	1995-10-23	1996-01-03	Orion Yhtymo Oy	New use of imidazole derivatives
DE10161818A1 (de) *	2001-12-14	2003-06-26	Gruenenthal Gmbh	Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
EP1807078A1 (en) *	2004-10-07	2007-07-18	Vitae Pharmaceuticals, Inc.	Diaminoalkane aspartic protease inhibitors
TWI411607B (zh) *	2005-11-14	2013-10-11	Vitae Pharmaceuticals Inc	天門冬胺酸蛋白酶抑制劑
CL2007002689A1 (es) *	2006-09-18	2008-04-18	Vitae Pharmaceuticals Inc	Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100317697A1 (en) *	2007-06-20	2010-12-16	Baldwin John J	Renin Inhibitors
EP2170815A2 (en) *	2007-06-20	2010-04-07	Vitae Pharmaceuticals, Inc.	Renin inhibitors
WO2009111685A1 (en)	2008-03-06	2009-09-11	Sensient Flavors Llc	Herbal extracts and flavor systems for oral products and methods of making the same
WO2009154766A1 (en) *	2008-06-20	2009-12-23	Vitae Pharmaceuticals, Inc.	Renin inhibitors and method of use thereof
JP2011525933A (ja) *	2008-06-26	2011-09-29	ヴァイティーファーマシューティカルズ，インコーポレイテッド	メチル２−（（ｒ）−（３−クロロフェニル）（（ｒ）−１−（（ｓ）−２−（メチルアミノ）−３−（（ｒ）−テトラヒドロ−２ｈ−ピラン−３−イル）プロピルカルバモイル）ピペリジン−３−イル）メトキシ）エチルカルバメートの塩
AR077692A1 (es) *	2009-08-06	2011-09-14	Vitae Pharmaceuticals Inc	Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
EP2670733B1 (en) *	2011-02-01	2019-04-10	The Board of Trustees of the University of Illionis	N-hydroxybenzamide derivatives as hdac inhibitors and therapeutic methods using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU518569B2 (en) *	1979-08-07	1981-10-08	Farmos-Yhtyma Oy	4-benzyl- and 4-benzoyl imidazole derivatives
US4303485A (en)	1979-08-20	1981-12-01	Minnesota Mining And Manufacturing Company	Ultraviolet polymerization of acrylate monomers using oxidizable tin compounds
GB2092569B (en) *	1981-02-05	1984-09-19	Farmos Oy	Substituted imidazole derivatives and their preparation and use
GB2101114B (en) *	1981-07-10	1985-05-22	Farmos Group Ltd	Substituted imidazole derivatives and their preparation and use
DE3635700A1 (de)	1986-10-21	1988-04-28	Michael Schmeller	Hubeinrichtung
GB8626287D0 (en) *	1986-11-04	1986-12-03	Ucb Sa	Substituted 1h-imidazoles
GB8714013D0 (en) *	1987-06-16	1987-07-22	Ici Plc	(substituted-aralkyl)heterocyclic compounds

1988
- 1988-04-28 GB GB888810067A patent/GB8810067D0/en active Pending
1989
- 1989-03-31 CA CA000595384A patent/CA1310966C/en not_active Expired - Lifetime
- 1989-04-06 US US07/334,854 patent/US4923865A/en not_active Expired - Fee Related
- 1989-04-20 ES ES89870054T patent/ES2052969T3/es not_active Expired - Lifetime
- 1989-04-20 AT AT89870054T patent/ATE82571T1/de active
- 1989-04-20 DE DE8989870054T patent/DE68903531T2/de not_active Expired - Fee Related
- 1989-04-20 EP EP89870054A patent/EP0341231B1/fr not_active Expired - Lifetime
- 1989-04-25 PH PH38563A patent/PH25461A/en unknown
- 1989-04-25 IL IL90087A patent/IL90087A0/xx not_active IP Right Cessation
- 1989-04-25 PL PL1989279104A patent/PL156250B1/pl unknown
- 1989-04-25 PL PL1989283865A patent/PL161362B1/pl unknown
- 1989-04-25 MY MYPI89000528A patent/MY104084A/en unknown
- 1989-04-26 FI FI891975A patent/FI101791B1/fi not_active IP Right Cessation
- 1989-04-26 IE IE136089A patent/IE63698B1/en not_active IP Right Cessation
- 1989-04-26 NZ NZ228897A patent/NZ228897A/xx unknown
- 1989-04-26 PT PT90368A patent/PT90368B/pt not_active IP Right Cessation
- 1989-04-27 AU AU33730/89A patent/AU610796B2/en not_active Ceased
- 1989-04-27 ZA ZA893140A patent/ZA893140B/xx unknown
- 1989-04-27 JP JP1109030A patent/JP2840288B2/ja not_active Expired - Lifetime
- 1989-04-27 NO NO891760A patent/NO173331C/no not_active IP Right Cessation
- 1989-04-27 RU SU894613927A patent/RU1830063C/ru active
- 1989-04-27 DK DK205589A patent/DK205589A/da unknown
- 1989-04-28 HU HU892041A patent/HU203877B/hu not_active IP Right Cessation
- 1989-04-28 KR KR1019890005825A patent/KR970011275B1/ko not_active Expired - Fee Related
- 1989-10-04 RU SU894742030A patent/RU1814647C/ru active
- 1989-10-04 UA UA4613927A patent/UA12835A1/uk unknown
1990
- 1990-04-05 RU SU904743506A patent/RU1836353C/ru active
1993
- 1993-01-21 GR GR930400087T patent/GR3006836T3/el unknown
- 1993-06-11 LV LVP-93-548A patent/LV10437B/lv unknown
- 1993-08-03 LT LTIP827A patent/LT3671B/lt not_active IP Right Cessation
1994
- 1994-02-02 HK HK94/94A patent/HK9494A/xx not_active IP Right Cessation
- 1994-07-15 CY CY175894A patent/CY1758A/xx unknown
1996
- 1996-09-23 BR BR1100052-0A patent/BR1100052A/pt active IP Right Grant
- 1996-10-17 BR BR1100064-3A patent/BR1100064A/pt active IP Right Grant

Also Published As

Publication number	Publication date
NZ228897A (en)	1990-08-28
EP0341231B1 (fr)	1992-11-19
LV10437A (lv)	1995-02-20
NO891760L (no)	1989-10-30
ZA893140B (en)	1990-01-31
US4923865A (en)	1990-05-08
PL161362B1 (pl)	1993-06-30
DE68903531T2 (de)	1993-04-29
EP0341231A1 (fr)	1989-11-08
DE68903531D1 (de)	1992-12-24
ES2052969T3 (es)	1994-07-16
GR3006836T3 (fi)	1993-06-30
PT90368B (pt)	1994-08-31
UA12835A1 (uk)	1997-02-28
RU1814647C (ru)	1993-05-07
MY104084A (en)	1993-11-30
JPH01313467A (ja)	1989-12-18
ATE82571T1 (de)	1992-12-15
LT3671B (en)	1996-01-25
RU1830063C (ru)	1993-07-23
NO173331C (no)	1993-12-08
BR1100052A (pt)	1999-12-07
JP2840288B2 (ja)	1998-12-24
AU610796B2 (en)	1991-05-23
RU1836353C (ru)	1993-08-23
FI891975A0 (fi)	1989-04-26
PT90368A (pt)	1989-11-10
AU3373089A (en)	1989-11-02
IE891360L (en)	1989-10-28
IL90087A0 (en)	1989-12-15
DK205589A (da)	1989-10-29
DK205589D0 (da)	1989-04-27
FI101791B (fi)	1998-08-31
LTIP827A (en)	1995-02-27
IE63698B1 (en)	1995-05-31
GB8810067D0 (en)	1988-06-02
HU203877B (en)	1991-10-28
FI101791B1 (fi)	1998-08-31
KR890016017A (ko)	1989-11-28
LV10437B (en)	1996-04-20
CA1310966C (en)	1992-12-01
KR970011275B1 (ko)	1997-07-09
PL156250B1 (pl)	1992-02-28
HUT51257A (en)	1990-04-28
CY1758A (en)	1994-07-15
BR1100064A (pt)	1999-12-07
NO891760D0 (no)	1989-04-27
PH25461A (en)	1991-07-01
NO173331B (no)	1993-08-23
HK9494A (en)	1994-02-09

Publication	Publication Date	Title
NO893248L (no)	1990-02-14	Triazolderivater.
NO891272L (no)	1989-09-25	Hydrogen.
DE68910214D1 (de)	1993-12-02	Bleiakkumulator.
FI881755A7 (fi)	1989-10-15	Faestmekanism foer ackumulator.
DK656689A (da)	1990-06-24	Triazolderivater
FI891975A7 (fi)	1989-10-29	Substituerade 1-(1h-imidazol-4-yl)-alkyl-bensamider.
FI880218A7 (fi)	1989-07-20	Oeppnings- och staengningsanordning foer taklucka i fordon.
DE58906128D1 (de)	1993-12-16	Substituierte Triazole.
DK483689A (da)	1990-04-04	Imidazolderivater
FI893188A0 (fi)	1989-06-29	I laengdriktningen hoptryckbar spole.
FI905632A7 (fi)	1991-05-16	Imidazolfungicider.
FI893541A0 (fi)	1989-07-24	Nytt uttryckningssystem.
FI893491A0 (fi)	1989-07-19	Triazol antifungala aemnen.
NL971040I2 (nl)	1998-01-05	1-Dimethylcarbamoyl-3-gesubstitueerde-5-gesubstitueerde-1H-1,2,4-triazolen.
FI854660A7 (fi)	1986-05-28	Triazol-antifungicider.
FI880813A7 (fi)	1988-09-21	Imidazolderivat.
FI874550A7 (fi)	1988-04-18	Imidazoler.
DK392889D0 (da)	1989-08-10	Imidazolderivater
FI844349A0 (fi)	1984-11-06	1-(aryl-2-halogen-1-etenyl)-1h -azoler.
FI851431A7 (fi)	1985-10-20	Imidatsolijohdannaisia.
FI892761A0 (fi)	1989-06-06	Expressionsvektorer foer framstaellning av ofusionerade proteiner i mikroorganismer.
NO904186D0 (no)	1990-09-26	Imidazoler.
ATE67191T1 (de)	1991-09-15	Imidazol-derivat.
DE3852873D1 (de)	1995-03-09	Imidazol-Derivat.
FI891507L (fi)	1989-10-21	Staell foer solfaongare.

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: UCB S.A.