LU91734I2 - Menveo - oligosaccharide méningococcique du group Y conjugué à la protéine CRM197 de Corynebacteriumdiphteriae. - Google Patents
Menveo - oligosaccharide méningococcique du group Y conjugué à la protéine CRM197 de Corynebacteriumdiphteriae.Info
- Publication number
- LU91734I2 LU91734I2 LU91734C LU91734C LU91734I2 LU 91734 I2 LU91734 I2 LU 91734I2 LU 91734 C LU91734 C LU 91734C LU 91734 C LU91734 C LU 91734C LU 91734 I2 LU91734 I2 LU 91734I2
- Authority
- LU
- Luxembourg
- Prior art keywords
- meningococcal
- corynebacteriumdiphteriae
- menveo
- oligosaccharide
- conjugated
- Prior art date
Links
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 title 1
- 229940124951 Menveo Drugs 0.000 title 1
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 abstract 1
- 229940001007 aluminium phosphate Drugs 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/04—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from fish or other sea animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09F—NATURAL RESINS; FRENCH POLISH; DRYING-OILS; OIL DRYING AGENTS, i.e. SICCATIVES; TURPENTINE
- C09F1/00—Obtaining purification, or chemical modification of natural resins, e.g. oleo-resins
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09G—POLISHING COMPOSITIONS; SKI WAXES
- C09G1/00—Polishing compositions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Formation And Processing Of Food Products (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0115176.0A GB0115176D0 (en) | 2001-06-20 | 2001-06-20 | Capular polysaccharide solubilisation and combination vaccines |
| PCT/IB2002/003191 WO2003007985A2 (fr) | 2001-06-20 | 2002-06-20 | Solubilisation de polysaccharides capsulaires et vaccins de combinaison |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LU91734I2 true LU91734I2 (fr) | 2011-03-14 |
| LU91734I9 LU91734I9 (fr) | 2019-01-07 |
Family
ID=9917070
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU91733C LU91733I2 (fr) | 2001-06-20 | 2010-09-14 | Menveo - oligosaccharide méningococcique du group W135 conjugué à la protéine CRM197 de Corynebacterium diphteriae. |
| LU91734C LU91734I2 (fr) | 2001-06-20 | 2010-09-14 | Menveo - oligosaccharide méningococcique du group Y conjugué à la protéine CRM197 de Corynebacteriumdiphteriae. |
| LU91732C LU91732I2 (fr) | 2001-06-20 | 2010-09-14 | Menveo- oligosaccharide méningococcique du group A conjugué à la protéine CRM197 de Corynebacterium diphteriae. |
| LU91778C LU91778I2 (fr) | 2001-06-20 | 2011-01-13 | Menveo - vaccin méningococcique des groupes A,C, W135 et Y conjugué. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU91733C LU91733I2 (fr) | 2001-06-20 | 2010-09-14 | Menveo - oligosaccharide méningococcique du group W135 conjugué à la protéine CRM197 de Corynebacterium diphteriae. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU91732C LU91732I2 (fr) | 2001-06-20 | 2010-09-14 | Menveo- oligosaccharide méningococcique du group A conjugué à la protéine CRM197 de Corynebacterium diphteriae. |
| LU91778C LU91778I2 (fr) | 2001-06-20 | 2011-01-13 | Menveo - vaccin méningococcique des groupes A,C, W135 et Y conjugué. |
Country Status (23)
| Country | Link |
|---|---|
| US (9) | US8753651B2 (fr) |
| EP (10) | EP2277539A3 (fr) |
| JP (4) | JP5075317B2 (fr) |
| CN (4) | CN101524534B (fr) |
| AT (3) | ATE322287T1 (fr) |
| AU (3) | AU2002321716B2 (fr) |
| BE (4) | BE2010C031I2 (fr) |
| BR (2) | BR122019009186B8 (fr) |
| CA (3) | CA2730856C (fr) |
| CY (6) | CY1110820T1 (fr) |
| DE (6) | DE60237123D1 (fr) |
| DK (6) | DK1741442T3 (fr) |
| ES (9) | ES2662015T3 (fr) |
| FR (4) | FR10C0042I1 (fr) |
| GB (1) | GB0115176D0 (fr) |
| LU (4) | LU91733I2 (fr) |
| MX (1) | MXPA03011462A (fr) |
| NL (3) | NL300458I2 (fr) |
| NZ (2) | NZ529881A (fr) |
| PT (6) | PT1401489E (fr) |
| RU (2) | RU2381814C2 (fr) |
| TR (2) | TR201808055T4 (fr) |
| WO (1) | WO2003007985A2 (fr) |
Families Citing this family (123)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| KR100947757B1 (ko) | 2001-01-23 | 2010-03-18 | 아벤티스 파스퇴르 | 다가 수막구균 폴리사카라이드―단백질 접합체 백신 |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| EP1490409B1 (fr) * | 2002-03-26 | 2008-12-31 | Novartis Vaccines and Diagnostics S.r.l. | Saccharides modifies presentant une stabilite amelioree dans l'eau |
| DE60328481D1 (de) | 2002-05-14 | 2009-09-03 | Novartis Vaccines & Diagnostic | Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält |
| GB0302218D0 (en) * | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
| EP1524992B1 (fr) * | 2002-08-02 | 2015-03-04 | GlaxoSmithKline Biologicals s.a. | Vaccins comprenants de lipooligosaccharides de immunotype l2 et/ou l3 de lgtb- neisseria meningitide |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| EP1549338B1 (fr) | 2002-10-11 | 2010-12-22 | Novartis Vaccines and Diagnostics S.r.l. | Vaccins polypeptidiques offrant une large protection contre des lignees de meningocoques hypervirulentes |
| DK2279746T3 (da) | 2002-11-15 | 2013-11-25 | Novartis Vaccines & Diagnostic | Overfladeproteiner i neisseria meningitidis |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| ES2383175T3 (es) * | 2003-01-30 | 2012-06-18 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
| CA2530364C (fr) * | 2003-06-23 | 2014-03-18 | Baxter International Inc. | Vaccins contre neisseria meningitidis du groupe y et combinaisons meningococciques desdits vaccins |
| GB0323103D0 (en) * | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| PL1670506T3 (pl) | 2003-10-02 | 2013-04-30 | Novartis Ag | Płynne szczepionki przeciw wielu grupom serologicznym meningokoków |
| GB0406013D0 (en) * | 2004-03-17 | 2004-04-21 | Chiron Srl | Analysis of saccharide vaccines without interference |
| GB0408978D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Meningococcal fermentation for preparing conjugate vaccines |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| WO2005105140A2 (fr) | 2004-04-30 | 2005-11-10 | Chiron Srl | Integration d'une vaccination conjuguee antimeningococcique |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| GB0411387D0 (en) | 2004-05-21 | 2004-06-23 | Chiron Srl | Analysis of saccharide length |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
| EP1784214A4 (fr) * | 2004-08-30 | 2009-09-23 | Sanofi Pasteur Inc | Conjugués polysaccharide/protéine dérivatisés de méningocoque multivalents et vaccin |
| EP2345422A1 (fr) * | 2004-09-21 | 2011-07-20 | Sanofi Pasteur, Inc. | Conjugués de polysaccharides-protéines dérivatisés méningococciques multivalents et vaccin |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0502095D0 (en) * | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| GB0502096D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Purification of streptococcal capsular polysaccharide |
| WO2006091517A2 (fr) | 2005-02-18 | 2006-08-31 | Novartis Vaccines And Diagnostics Inc. | Immunogenes d'escherichia coli uropathogene |
| SG160329A1 (en) | 2005-02-18 | 2010-04-29 | Novartis Vaccines & Diagnostic | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli |
| GB0505518D0 (en) | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| DK1868645T3 (da) | 2005-04-08 | 2012-04-10 | Wyeth Llc | Multivalent pneumokok-sakkarid-protein-konjugat-sammensætning |
| EP1871411A4 (fr) | 2005-04-18 | 2010-07-21 | Novartis Vaccines & Diagnostic | Procede pour exprimer un antigene de surface de virus de l'hepatite b afin de preparer un vaccin |
| GB0513071D0 (en) * | 2005-06-27 | 2005-08-03 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0513069D0 (en) * | 2005-06-27 | 2005-08-03 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| BRPI0612655B1 (pt) * | 2005-06-27 | 2021-06-15 | Pfizer Ireland Pharmaceuticals | Composição imunogênica |
| AU2006286228A1 (en) | 2005-09-01 | 2007-03-08 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Multiple vaccination including serogroup C meningococcus |
| ES2522521T3 (es) * | 2005-09-05 | 2014-11-14 | Glaxosmithkline Biologicals Sa | Ensayo bactericida del suero para antisueros específicos de N. meningitidis |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| KR20130135399A (ko) | 2006-03-17 | 2013-12-10 | 더 거버먼트 오브 더 유나이티드 스테이츠 오브 아메리카 에즈 레프리젠티드 바이 더 세크러테리 오브 더 디파트먼트 오브 헬스 앤드 휴먼 서비시즈 | 복합 다가 면역원성 콘쥬게이트의 제조 방법 |
| US10828361B2 (en) * | 2006-03-22 | 2020-11-10 | Glaxosmithkline Biologicals Sa | Regimens for immunisation with meningococcal conjugates |
| PL2004225T3 (pl) | 2006-03-22 | 2012-09-28 | Novartis Ag | Schematy immunizacji koniugatami meningokokowymi |
| GB0605757D0 (en) | 2006-03-22 | 2006-05-03 | Chiron Srl | Separation of conjugated and unconjugated components |
| TW200806315A (en) * | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
| CN101081296B (zh) * | 2006-05-29 | 2010-08-04 | 北京民海生物科技有限公司 | 一种b型流感嗜血杆菌荚膜多糖制备方法及其联合疫苗 |
| US7491517B2 (en) | 2006-07-19 | 2009-02-17 | Jeeri R Reddy | Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135 |
| RU2322503C1 (ru) * | 2006-07-21 | 2008-04-20 | Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации | Способ получения высокоспецифичной гетерологичной антирабической сыворотки |
| CA2659552A1 (fr) | 2006-08-16 | 2008-02-21 | Novartis Ag | Immunogenes pour escherichia coli uropathogene |
| JP5260531B2 (ja) * | 2006-10-10 | 2013-08-14 | ワイス・エルエルシー | 肺炎連鎖球菌3型多糖体の精製 |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| KR101500771B1 (ko) * | 2007-03-23 | 2015-03-18 | 와이어쓰 엘엘씨 | 스트렙토코커스 뉴모니아 협막 다당류를 제조하기 위한 단축 정제 방법 |
| EP2155244B1 (fr) * | 2007-04-23 | 2017-03-22 | Serum Institute of India Private Limited | Polysaccharides antigéniques et procédé pour leur préparation |
| AU2008259423A1 (en) * | 2007-06-04 | 2008-12-11 | Novartis Ag | Formulation of meningitis vaccines |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
| NZ583750A (en) * | 2007-09-11 | 2012-05-25 | Univ Guelph | Novel polysaccharide immunogens from clostridium difficile |
| BR122016015627A2 (pt) | 2007-10-19 | 2018-10-30 | Novartis Ag | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
| CA2716212A1 (fr) | 2008-02-21 | 2009-08-27 | Novartis Ag | Polypeptides fhbp a meningocoques |
| CN101724085B (zh) * | 2008-10-22 | 2011-09-21 | 上海生物制品研究所 | 一种荚膜多糖纯化方法 |
| ES2586308T3 (es) | 2008-10-27 | 2016-10-13 | Glaxosmithkline Biologicals Sa | Procedimiento de purificación de un hidrato de carbono de Streptococcus del grupo A |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| GB0822633D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| WO2010070453A2 (fr) | 2008-12-17 | 2010-06-24 | Novartis Ag | Vaccins méningococciques comprenant un récepteur de l'hémoglobine |
| EP3017828A1 (fr) | 2009-08-27 | 2016-05-11 | GlaxoSmithKline Biologicals SA | Polypeptides hybrides contenant des séquences fhbp à méningocoques |
| RU2603267C2 (ru) | 2009-09-30 | 2016-11-27 | Новартис Аг | Конъюгация капсульных полисахаридов staphylococcus aureus типа 5 и типа 8 |
| CN102917730A (zh) | 2009-10-27 | 2013-02-06 | 诺华有限公司 | 修饰的脑膜炎球菌fHBP多肽 |
| CA2779578A1 (fr) | 2009-10-30 | 2011-05-05 | Novartis Ag | Purification de saccharides capsulaires de staphylococcus aureus de type 5 et de type 8 |
| WO2012020326A1 (fr) | 2010-03-18 | 2012-02-16 | Novartis Ag | Vaccins adjuvantés contre le méningocoque de sérogroupe b |
| ES2994878T3 (en) | 2010-08-23 | 2025-02-03 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
| ES2744471T3 (es) | 2010-09-04 | 2020-02-25 | Glaxosmithkline Biologicals Sa | Ensayos de anticuerpos bactericidas para evaluar la inmunogenia y la potencia de vacunas de sacárido capsular meningocócico |
| KR101584871B1 (ko) | 2010-09-10 | 2016-01-22 | 와이어쓰 엘엘씨 | 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체 |
| GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
| US20130315959A1 (en) | 2010-12-24 | 2013-11-28 | Novartis Ag | Compounds |
| CA2828844C (fr) | 2011-03-02 | 2020-07-14 | Novartis Ag | Vaccins combines comprenant des doses inferieures d'antigene et/ou d'adjuvant |
| US9149541B2 (en) | 2011-07-08 | 2015-10-06 | Novartis Ag | Tyrosine ligation process |
| CU20110202A7 (es) | 2011-11-02 | 2013-12-27 | Inst Finlay Ct De Investigación Producción De Sueros Y Vacunas | Composición inmunogénica de polisacáridos planos adyuvados y las formulaciones resultantes |
| RU2636350C2 (ru) * | 2011-11-07 | 2017-11-22 | Новартис Аг | МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021 |
| DK2809349T3 (da) * | 2012-01-30 | 2019-02-18 | Serum Institute Of India Pvt Ltd | Immunogen sammensætning |
| EP2822584A1 (fr) | 2012-03-08 | 2015-01-14 | Novartis AG | Vaccins combinés comprenant des agonistes du tlr4 |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| BR122016004924A2 (pt) | 2012-03-09 | 2019-07-30 | Pfizer Inc. | Polipeptídeo isolado e composições imunogênicas compreendendo os mesmos |
| SG11201407440WA (en) | 2012-05-22 | 2014-12-30 | Novartis Ag | Meningococcus serogroup x conjugate |
| CN104487086B (zh) * | 2012-07-07 | 2019-08-30 | 巴拉特生物技术国际有限公司 | 无动物源的不含酒精的疫苗组合物及其制备方法 |
| CN103623404B (zh) * | 2012-08-28 | 2016-08-03 | 天士力制药集团股份有限公司 | 一种b型流感嗜血杆菌多糖结合疫苗的制备方法 |
| CA2882619A1 (fr) | 2012-09-06 | 2014-03-13 | Novartis Ag | Vaccins combinatoires avec meningococcus de serogroupe b et d/t/p |
| MX364644B (es) * | 2012-11-21 | 2019-05-03 | Serum Inst India Ltd | Produccion de altos rendimientos de polisacaridos bacteriales. |
| BR112015014250A2 (pt) | 2012-12-18 | 2017-07-11 | Glaxosmithkline Biologicals Sa | método para imunizar um bebê, vacina de combinação e, kit |
| EP2964665B1 (fr) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Polypeptides immunogènes de fusion |
| MX2016000393A (es) | 2013-07-11 | 2016-10-26 | Novartis Ag | Modificaciones de proteinas quimioenzimaticas de lisina utilizando transglutaminasa microbiana. |
| WO2015005961A1 (fr) | 2013-07-12 | 2015-01-15 | Emd Millipore Corporation | Méthode permettant de déterminer si un virus peut être éliminé d'un échantillon contenant une protéine cible à l'aide de charbon actif |
| CA2923129C (fr) | 2013-09-08 | 2020-06-09 | Pfizer Inc. | Compositions utilisables contre neisseria meningitidis et procedes associes |
| RS61246B1 (sr) | 2014-02-28 | 2021-01-29 | Glaxosmithkline Biologicals Sa | Modifikovani meningokokni fhbp polipeptidi |
| EP3148577B1 (fr) | 2014-05-24 | 2021-01-20 | Biological E Limited | Nouveau vaccin conjugué méningococcique semi-synthétique |
| CN104548090B (zh) * | 2015-01-27 | 2016-11-30 | 中国科学院过程工程研究所 | 一种β-葡聚糖修饰的脑膜炎多糖结合疫苗及其制备方法 |
| WO2016132294A1 (fr) | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Compositions de neisseria meningitidis et méthodes associées |
| CN105037579A (zh) * | 2015-08-31 | 2015-11-11 | 成都欧林生物科技股份有限公司 | A群脑膜炎球菌细菌荚膜粗多糖的制备工艺 |
| EP3439704A1 (fr) | 2016-04-05 | 2019-02-13 | GSK Vaccines S.r.l. | Compositions immunogènes |
| EP4309670A3 (fr) | 2016-09-02 | 2024-07-17 | Sanofi Pasteur, Inc. | Vaccin contre neisseria meningitidis |
| US12161707B2 (en) | 2016-09-02 | 2024-12-10 | Glaxosmithkline Biologicals Sa | Vaccines for Neisseria gonorrhoeae |
| US11951165B2 (en) * | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| CN110366428B (zh) | 2016-12-30 | 2024-05-17 | Vaxcyte公司 | 具有非天然氨基酸的多肽-抗原缀合物 |
| US10183070B2 (en) | 2017-01-31 | 2019-01-22 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US11246918B2 (en) | 2017-02-03 | 2022-02-15 | Eva Barbara Schadeck | Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof |
| WO2018156467A1 (fr) * | 2017-02-24 | 2018-08-30 | Merck Sharp & Dohme Corp. | Procédés d'amélioration de la filtrabilité de réactions de polysaccharide conjugué à une protéine |
| US11400162B2 (en) | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| GEAP202215229A (en) | 2017-05-05 | 2022-03-10 | Serum Institute Of India Pvt Ltd | Method for removal of impurities from bacterial capsular polysaccharide based preparations |
| US20200247911A1 (en) * | 2017-05-17 | 2020-08-06 | Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. | Purification of Bacterial Polysaccharides |
| JP2020533299A (ja) * | 2017-09-07 | 2020-11-19 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | キャリアタンパク質へのコンジュゲーションのための肺炎球菌多糖の製剤方法 |
| WO2019175900A1 (fr) * | 2018-03-16 | 2019-09-19 | Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. | Purification de polysaccharides de neisseria meningitidis |
| JP7728704B2 (ja) * | 2019-03-08 | 2025-08-25 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 炭素環誘導体及びそれらのコンジュゲート誘導体、並びにワクチンにおけるそれらの使用 |
| MX2021013736A (es) | 2019-05-10 | 2021-12-10 | Glaxosmithkline Biologicals Sa | Produccion de conjugados. |
| WO2021059181A1 (fr) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Compositions de neisseria meningitidis et méthodes associées |
| US12533418B2 (en) | 2019-11-22 | 2026-01-27 | Glaxosmithkline Biologicals Sa | Dosage and administration of a bacterial saccharide glycoconjugate vaccine |
| GB202013262D0 (en) | 2020-08-25 | 2020-10-07 | Glaxosmithkline Biologicals Sa | Vaccine Composition |
| CN115721709A (zh) * | 2021-08-27 | 2023-03-03 | 康希诺生物股份公司 | 一种肺炎球菌结合疫苗制备方法 |
| GB202115151D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Methods |
| GB202208093D0 (en) | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| GB202208089D0 (en) | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
Family Cites Families (147)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB207117A (en) | 1923-04-05 | 1923-11-22 | Fernand Prosper Constant Lebru | Improvements in otter boards |
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| US4123520A (en) * | 1977-08-01 | 1978-10-31 | Merck & Co., Inc. | Method for preparing high molecular weight meningococcal Group C vaccine |
| US4134214A (en) | 1977-08-05 | 1979-01-16 | Merck & Co., Inc. | Freeze-drying process for the preparation of meningococcus vaccine without degradation of potency |
| DE2748132A1 (de) | 1977-10-27 | 1979-05-03 | Behringwerke Ag | Stabilisator fuer polysaccharid |
| US4220717A (en) * | 1977-12-22 | 1980-09-02 | American Cyanamid Company | Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b. |
| US4242501A (en) * | 1979-08-08 | 1980-12-30 | American Cyanamid Company | Purification of pneumococcal capsular polysaccharides |
| US4351762A (en) * | 1981-03-10 | 1982-09-28 | Bioresearch, Inc. | Rapid, quantitative peptide synthesis using mixed anhydrides |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| BE889979A (fr) | 1981-08-14 | 1982-02-15 | Smith Kline Rit | Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4902506A (en) | 1983-07-05 | 1990-02-20 | The University Of Rochester | Immunogenic conjugates |
| US4451446A (en) * | 1982-03-04 | 1984-05-29 | Smithkline-Rit | Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them |
| US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
| EP0109688A3 (fr) | 1982-11-23 | 1986-12-03 | The Wellcome Foundation Limited | Complexes, procédés pour leur obtention et formulations contenant de tels complexes |
| JPS59176214A (ja) * | 1982-11-23 | 1984-10-05 | ザ・ウエルカム・フアウンデ−シヨン・リミテツド | 抗原性組成物 |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4762713A (en) * | 1983-07-05 | 1988-08-09 | The University Of Rochester | Boosting of immunogenic conjugate vaccinations by unconjugated bacterial capsular polymers |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| EP0145359B1 (fr) * | 1983-11-21 | 1991-01-16 | The Wellcome Foundation Limited | Complexes, leur procédé de préparation et formulations les contenant |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US4882317A (en) | 1984-05-10 | 1989-11-21 | Merck & Co., Inc. | Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| US4814276A (en) * | 1986-04-25 | 1989-03-21 | Becton, Dickinson And Company | Selective medium for growth of neisseria |
| US4877613A (en) | 1987-08-05 | 1989-10-31 | Biotech Connections, Inc. | Process for preparing veterinary acellular vaccines against gram-negative nonenteric pathogenic bacilli |
| US4761713A (en) * | 1987-11-06 | 1988-08-02 | North American Philips Corp. | Glycol based mid-volt capacitor |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| ES2070312T5 (es) | 1988-12-19 | 2003-05-16 | American Cyanamid Co | Vacuna de proteina de membrana exterior meningococica de clase 1. |
| CA2006700A1 (fr) | 1989-01-17 | 1990-07-17 | Antonello Pessi | Peptides synthetiques et leur utilisation comme porteurs universels pour la preparation de conjugats immunogenes convenant a la mise au point de vaccins synthetiques |
| US4963534A (en) | 1989-05-19 | 1990-10-16 | Merck & Co., Inc. | Process for solubilizing polyanoinic bacterial polysaccharides in aprotic solvents |
| WO1990014837A1 (fr) | 1989-05-25 | 1990-12-13 | Chiron Corporation | Composition d'adjuvant comprenant une emulsion de gouttelettes d'huile d'une taille inferieure au micron |
| KR920703114A (ko) | 1989-07-14 | 1992-12-17 | 원본미기재 | 접합체 백신을 위한 시토킨 및 호르몬 운반체 |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| DK0504202T3 (da) * | 1989-12-14 | 1995-10-02 | Ca Nat Research Council | Forbedret meningokok-polysaccharid-konjugat vaccine |
| SU1750689A1 (ru) * | 1990-05-17 | 1992-07-30 | Научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова | Способ получени полисахаридно-белковой вакцины против NeISSeRIa меNINGIтIDIS серогруппы В |
| IL98715A0 (en) | 1990-08-13 | 1992-07-15 | American Cyanamid Co | Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines |
| US5256294A (en) * | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| CA2059692C (fr) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Vaccin conjugue de polysaccharide contre les pneumocoques |
| CA2059693C (fr) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Antigenes polysaccharides de streptococcus pneumoniae |
| CA2101648C (fr) * | 1991-03-12 | 2003-09-09 | Rachel Schneerson | Conjugues polysaccharide-proteine |
| HU9400426D0 (en) * | 1991-08-16 | 1994-05-30 | Merck & Co Inc | Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide |
| US5314811A (en) * | 1992-07-13 | 1994-05-24 | Merck & Co., Inc. | Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide |
| FR2682388B1 (fr) * | 1991-10-10 | 1995-06-09 | Pasteur Merieux Serums Vacc | Procede de preparation d'un oligoside par depolymerisation d'un polyoside issu d'un agent pathogene, oligoside ainsi obtenu et son utilisation notamment comme agent vaccinal. |
| DE69334197T2 (de) | 1992-03-02 | 2008-12-11 | Novartis Vaccines And Diagnostics S.R.L. | Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| UA40596C2 (uk) | 1992-05-23 | 2001-08-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини та спосіб її одержання |
| DE69327599T2 (de) | 1992-06-25 | 2000-08-10 | Smithkline Beecham Biolog | Adjuvantien enthaltende Impfstoffzusammensetzung |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| AU685443B2 (en) | 1993-03-23 | 1998-01-22 | Smithkline Beecham Biologicals (Sa) | Vaccine compositions containing 3-O deacylated monophosphoryl lipid A |
| KR100376361B1 (ko) | 1993-09-22 | 2003-07-18 | 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신 | 면역원성구조체의제조를위하여신규한시아닐레이팅시약을사용하여용해성탄수화물을활성화하는방법 |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| JPH10502365A (ja) | 1994-07-01 | 1998-03-03 | リカン・リミテッド | ヘリコバクタータンパク質およびワクチン |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| ATE420171T1 (de) | 1994-07-15 | 2009-01-15 | Univ Iowa Res Found | Immunomodulatorische oligonukleotide |
| GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| US6696065B1 (en) * | 1995-05-04 | 2004-02-24 | Aventis Pastuer Limited | Acellular pertussis vaccines and methods of preparation thereof |
| US20030157129A1 (en) * | 1995-06-23 | 2003-08-21 | Smithkline Beecham Biologicals S.A. | Vaccine comprising a polysaccharide antigen - carrier protein conjugate and free carrier protein |
| HUP9802199A3 (en) | 1995-06-07 | 1999-07-28 | Smithkline Beecham Biolog | Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein and use of |
| US5811102A (en) * | 1995-06-07 | 1998-09-22 | National Research Council Of Canada | Modified meningococcal polysaccharide conjugate vaccines |
| ATE433329T1 (de) | 1995-06-23 | 2009-06-15 | Glaxosmithkline Biolog Sa | Impfstoff bestehend aus auf aluminium-phosphat adsorbiertem, konjugiertem polysaccharid antigen |
| US20020054884A1 (en) * | 1995-06-23 | 2002-05-09 | Smithkline Beecham Biologicals, Sa | Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| DE69737413T2 (de) | 1996-01-04 | 2007-10-31 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Bakterioferritin aus helicobacter pylori |
| HUP9901039A2 (hu) | 1996-02-01 | 1999-07-28 | North American Vaccine, Inc. | Neisseria meningitidis B-csoportba tartozó külső-membrán-fehérjéjének (MB3) expressziója élesztőben, továbbá vakcinák |
| JP3990455B2 (ja) | 1996-02-14 | 2007-10-10 | メルク エンド カンパニー インコーポレーテッド | 多糖沈殿法 |
| DE19630390A1 (de) | 1996-07-26 | 1998-01-29 | Chiron Behring Gmbh & Co | Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung |
| ATE208629T1 (de) | 1996-08-27 | 2001-11-15 | Chiron Corp | Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung |
| EP0930893B1 (fr) | 1996-10-11 | 2005-04-13 | The Regents of The University of California | Conjugues polynucleotide immunostimulateur/molecule immunomodulatrice |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6248334B1 (en) * | 1997-01-08 | 2001-06-19 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process |
| EP0959905B1 (fr) | 1997-01-21 | 2009-12-09 | Sanofi Pasteur | Conjugues de polysaccharide et de peptide |
| US6891037B1 (en) | 1997-01-24 | 2005-05-10 | Schweiz. Serum- & Impfinstitut Bern | Method for the isolation of polysaccharides |
| EP1039935A4 (fr) | 1997-02-28 | 2005-04-27 | Univ Iowa Res Found | UTILISATION D'ACIDES NUCLEIQUES CONTENANT DES DINUCLEOTIDES CpG NON METHYLES DANS LE TRAITEMENT DES TROUBLES ASSOCIES AUX LIPOPOLYSACCHARIDES |
| ATE441432T1 (de) | 1997-03-10 | 2009-09-15 | Ottawa Hospital Res Inst | Verwendung von nicht-methyliertem cpg dinukleotid in kombination mit aluminium als adjuvantien |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| US6403306B1 (en) | 1997-04-09 | 2002-06-11 | Emory University | Serogroup-specific nucleotide sequences in the molecular typing of bacterial isolates and the preparation of vaccines thereto |
| EP0977588B1 (fr) | 1997-04-24 | 2004-10-06 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Couplage de proteines non modifiees a des polysaccharides derives d'haloacyle ou de dihaloacyle pour la preparation de vaccins renfermant des proteines-polysaccharides |
| ATE370740T1 (de) | 1997-05-20 | 2007-09-15 | Ottawa Health Research Inst | Verfahren zur herstellung von nukleinsäurekonstrukten |
| EP1849860B1 (fr) | 1997-05-28 | 2010-11-17 | Novartis Vaccines and Diagnostics S.r.l. | Procédé de préparation d'un facteur immunogene de Corynebacterium diphtheriae en utilisant un milieu de culture avec extrait de levure en tant que source d'acides aminés et dépourvu de complexes protéiques d'origine animale |
| AU753172B2 (en) | 1997-06-06 | 2002-10-10 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| JP2002506448A (ja) * | 1997-06-24 | 2002-02-26 | カイロン コーポレイション | 抗髄膜炎菌ワクチン組成物を使用して成体を免疫する方法 |
| AU9120898A (en) * | 1997-08-27 | 1999-03-16 | Chiron Corporation | Molecular mimetics of meningococcal b epitopes |
| EP1279401B1 (fr) | 1997-09-05 | 2008-01-09 | GlaxoSmithKline Biologicals S.A. | Emulsions du type huile-dans-l'eau contenant des saponines |
| US5965714A (en) | 1997-10-02 | 1999-10-12 | Connaught Laboratories, Inc. | Method for the covalent attachment of polysaccharides to protein molecules |
| ATE476508T1 (de) | 1997-11-06 | 2010-08-15 | Novartis Vaccines & Diagnostic | Neisseriale antigene |
| KR20010032336A (ko) | 1997-11-21 | 2001-04-16 | 브랑디 빠스깔 | 클라미디아 뉴모니아 게놈 서열과 폴리펩티드, 이의 단편및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도 |
| GB9725084D0 (en) | 1997-11-28 | 1998-01-28 | Medeva Europ Ltd | Vaccine compositions |
| CN1280619A (zh) | 1997-11-28 | 2001-01-17 | 根瑟特公司 | 沙眼衣原体的基因组序列和多肽,其片段以及其用途,特别是用于诊断、预防和治疗感染 |
| HUP0100623A3 (en) | 1997-12-23 | 2003-11-28 | Baxter Healthcare S A Wallisel | Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines |
| ES2333071T5 (es) | 1998-01-14 | 2015-08-17 | Novartis Vaccines And Diagnostics S.R.L. | Antígenos de Neisseria meningitidis |
| US7018637B2 (en) | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| GB9806456D0 (en) * | 1998-03-25 | 1998-05-27 | Smithkline Beecham Biolog | Vaccine composition |
| EP1069910A1 (fr) | 1998-04-09 | 2001-01-24 | GlaxoSmithKline Biologicals S.A. | Compositions adjuvantes |
| BR9910089A (pt) | 1998-05-01 | 2004-06-08 | Chiron Corp | Composições e antìgenos de neisseria meningitidis |
| DE69934225T2 (de) † | 1998-05-29 | 2007-09-27 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Kombinierte meningitis b/c impfstoffe |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| NZ509986A (en) | 1998-08-19 | 2003-10-31 | Baxter Healthcare S | Immunogenic beta-propionamido-linked polysaccharide and oligosaccharide protein conjugates as vaccines |
| US6128656A (en) * | 1998-09-10 | 2000-10-03 | Cisco Technology, Inc. | System for updating selected part of configuration information stored in a memory of a network element depending on status of received state variable |
| JP2004511201A (ja) | 1998-10-09 | 2004-04-15 | カイロン コーポレイション | ナイセリアゲノム配列およびそれらの使用方法 |
| CZ301212B6 (cs) | 1998-10-16 | 2009-12-09 | Smithkline Beecham Biologicals S. A. | Vakcinacní prostredek |
| AU1722300A (en) | 1998-11-12 | 2000-05-29 | Regents Of The University Of California, The | Chlamydia pneumoniae genome sequence |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US6146902A (en) | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
| DE122009000054I1 (de) * | 1999-03-19 | 2009-12-31 | Glaxosmithkline Biolog Sa | Impfstoff gegen bakterielle antigene |
| FR2791895B1 (fr) | 1999-03-23 | 2001-06-15 | Pasteur Merieux Serums Vacc | Utilisation de trehalose pour stabiliser un vaccin liquide |
| WO2000061761A2 (fr) | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Support proteique recombinant de la toxine a pour vaccins conjugues polysaccharides |
| HK1044484B (en) | 1999-04-19 | 2005-07-29 | Smithkline Beecham Biologicals S.A. | Adjuvant composition containing saponin and immunostimulatory oligonucleotide |
| ES2563650T3 (es) | 1999-05-19 | 2016-03-15 | Glaxosmithkline Biologicals Sa | Composiciones de combinaciones de Neisseria |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| US6531131B1 (en) * | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
| HK1046861A1 (zh) | 1999-09-24 | 2003-01-30 | Smithkline Beecham Biologicals S.A. | 包括聚氧乙烯烷基酯或者醚以及至少一種非離子表面活性劑的佐劑 |
| CO5200837A1 (es) | 1999-09-24 | 2002-09-27 | Smithkline Beecham Corp | Vacunas |
| GB9925559D0 (en) | 1999-10-28 | 1999-12-29 | Smithkline Beecham Biolog | Novel method |
| JP4948731B2 (ja) * | 1999-12-02 | 2012-06-06 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 凍結乾燥の際に生物学的分子を安定化するための組成物および方法 |
| PT1248647E (pt) | 2000-01-17 | 2010-11-18 | Novartis Vaccines & Diagnostics Srl | Vacina de vesícula da membrana externa (omv) compreendendo proteínas de membrana externa de n. meningitidis do serogrupo b |
| ES2299476T3 (es) | 2000-02-28 | 2008-06-01 | Novartis Vaccines And Diagnostics S.R.L. | Expresion hibrida de proteinas de neisseria. |
| US6800455B2 (en) * | 2000-03-31 | 2004-10-05 | Scios Inc. | Secreted factors |
| GB0108364D0 (en) * | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
| CN1449293B (zh) | 2000-06-29 | 2012-08-22 | 史密丝克莱恩比彻姆生物有限公司 | 多价疫苗组合物 |
| WO2002002606A2 (fr) | 2000-07-03 | 2002-01-10 | Chiron S.P.A. | Immunisation contre une infection par chlamydia pneumoniae |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| AU9489801A (en) * | 2000-09-28 | 2002-04-08 | Chiron Corp | Microparticle compositions and methods for the manufacture thereof |
| NZ560966A (en) | 2000-10-27 | 2010-06-25 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
| KR100947757B1 (ko) | 2001-01-23 | 2010-03-18 | 아벤티스 파스퇴르 | 다가 수막구균 폴리사카라이드―단백질 접합체 백신 |
| JP2004527524A (ja) * | 2001-04-05 | 2004-09-09 | カイロン コーポレイション | 非経口初回抗原刺激後の粘膜追加免疫 |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| WO2003028661A2 (fr) | 2001-10-03 | 2003-04-10 | Chiron Corporation | Compositions de meningocoque assorties d'un adjuvant |
| EP1490409B1 (fr) | 2002-03-26 | 2008-12-31 | Novartis Vaccines and Diagnostics S.r.l. | Saccharides modifies presentant une stabilite amelioree dans l'eau |
| WO2003094960A2 (fr) | 2002-05-14 | 2003-11-20 | Chiron Srl | Vaccins combines destines a etre administres aux muqueuses pour l'immunisation contre la meningite bacterienne |
| GB0302218D0 (en) | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
| GB0220198D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
| EP1549338B1 (fr) | 2002-10-11 | 2010-12-22 | Novartis Vaccines and Diagnostics S.r.l. | Vaccins polypeptidiques offrant une large protection contre des lignees de meningocoques hypervirulentes |
| ES2383175T3 (es) * | 2003-01-30 | 2012-06-18 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0409745D0 (en) * | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| PL2004225T3 (pl) * | 2006-03-22 | 2012-09-28 | Novartis Ag | Schematy immunizacji koniugatami meningokokowymi |
| US10828361B2 (en) * | 2006-03-22 | 2020-11-10 | Glaxosmithkline Biologicals Sa | Regimens for immunisation with meningococcal conjugates |
| GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| GB2495341B (en) * | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
-
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