LT3969B - Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen - Google Patents
Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen Download PDFInfo
- Publication number
- LT3969B LT3969B LT95-028A LT95028A LT3969B LT 3969 B LT3969 B LT 3969B LT 95028 A LT95028 A LT 95028A LT 3969 B LT3969 B LT 3969B
- Authority
- LT
- Lithuania
- Prior art keywords
- pranoprofen
- stabilizing
- antioxidant
- aqueous solution
- container
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
- Y10T428/1393—Multilayer [continuous layer]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4418494 | 1994-03-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LT95028A LT95028A (en) | 1995-10-25 |
| LT3969B true LT3969B (en) | 1996-05-27 |
Family
ID=12684495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LT95-028A LT3969B (en) | 1994-03-15 | 1995-03-14 | Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5856345A (zh) |
| EP (2) | EP0672414B1 (zh) |
| KR (1) | KR100338851B1 (zh) |
| CN (1) | CN1091597C (zh) |
| AT (1) | ATE297206T1 (zh) |
| AU (1) | AU707119B2 (zh) |
| BR (1) | BR9501081A (zh) |
| CA (1) | CA2144591A1 (zh) |
| DE (1) | DE69534258T2 (zh) |
| EE (1) | EE9500015A (zh) |
| ES (1) | ES2240966T3 (zh) |
| FI (1) | FI951190L (zh) |
| HU (1) | HUT71245A (zh) |
| LT (1) | LT3969B (zh) |
| LV (1) | LV10922B (zh) |
| NO (1) | NO950970L (zh) |
| PL (1) | PL179534B1 (zh) |
| RU (1) | RU2148402C1 (zh) |
| TW (1) | TW358812B (zh) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6235781B1 (en) | 1998-07-14 | 2001-05-22 | Alcon Laboratories, Inc. | Prostaglandin product |
| AU1750500A (en) * | 1998-12-02 | 2000-06-19 | Copa Distributors, Llc | Gradual hair relaxation composition |
| US8877168B1 (en) | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| WO2004022032A2 (en) * | 2002-07-31 | 2004-03-18 | Pharmacia Corporation | Pharmaceutical dosage form comprising a sulfite compound |
| JP3631748B2 (ja) | 2002-07-31 | 2005-03-23 | 千寿製薬株式会社 | 水性液剤および光安定化された水性液剤 |
| KR101059711B1 (ko) | 2003-01-21 | 2011-08-29 | 센주 세이야꾸 가부시키가이샤 | 2-아미노-3-(4-브로모벤조일)페닐아세트산 함유 수성액제 |
| AU2003100262B4 (en) * | 2003-04-07 | 2003-09-18 | Jurox Pty Ltd | Stable carprofen composition |
| US7125497B1 (en) * | 2003-05-22 | 2006-10-24 | Sandia Corporation | Reactive formulations for a neutralization of toxic industrial chemicals |
| EP1627644A4 (en) * | 2003-05-23 | 2012-01-18 | Hisamitsu Pharmaceutical Co | PREPARATION FOR EXTERNAL PERCUTANEOUS ADMINISTRATION WITH AN NON-TEROIDAL INFLAMMATORY MEDICAMENT AND AN INTERLEUKIN 1A PRODUCTION INHIBITOR |
| US20060073172A1 (en) * | 2004-10-01 | 2006-04-06 | Schneider L W | Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure |
| ES2363964B1 (es) | 2009-11-20 | 2012-08-22 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados. |
| JP5580944B2 (ja) * | 2011-12-27 | 2014-08-27 | 千寿製薬株式会社 | ジブチルヒドロキシトルエン含有製剤及びジブチルヒドロキシトルエンの安定化方法 |
| CN104136019A (zh) * | 2012-02-27 | 2014-11-05 | 日本乐敦制药株式会社 | 眼科用组合物试剂盒 |
| WO2014129466A1 (ja) * | 2013-02-19 | 2014-08-28 | ロート製薬株式会社 | 網膜疾患の予防、改善、又は治療用粘膜適用剤 |
| JP5340498B1 (ja) * | 2013-03-11 | 2013-11-13 | 千寿製薬株式会社 | ソフトコンタクトレンズ用眼科用組成物 |
| RU2674657C2 (ru) * | 2013-05-30 | 2018-12-12 | Сэндзю Фармасьютикал Ко., Лтд. | Способ стабилизации хлорфенирамина и его соли |
| TWI644663B (zh) * | 2014-03-10 | 2018-12-21 | 日商千壽製藥股份有限公司 | 二丁基羥基甲苯的穩定化方法,及含二丁基羥基甲苯之製品(一) |
| TW201540292A (zh) * | 2014-03-10 | 2015-11-01 | Senju Pharma Co | 二丁基羥基甲苯的穩定化方法(二) |
| AR102172A1 (es) | 2015-10-05 | 2017-02-08 | Química Luar S R L | Una composición farmacéutica bactericida y virucida |
| KR102478553B1 (ko) * | 2018-02-28 | 2022-12-16 | 한림제약(주) | 벤조피란 유도체 또는 이의 약학적으로 허용가능한 염을 포함하는 용액 형태의 점안제 |
| US12324853B2 (en) | 2020-08-10 | 2025-06-10 | Quimica Luar S.R.L. | Methods for treating respiratory viral infections |
| CN115677733A (zh) * | 2022-12-20 | 2023-02-03 | 济南宣正药业有限公司 | 一种用于普拉洛芬质量研究的化合物及其制备方法和应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931295A (en) | 1974-07-23 | 1976-01-06 | Universal Oil Products Company | Hydroxylation of aromatic compounds |
| US4607038A (en) | 1984-03-01 | 1986-08-19 | Yoshitomi Pharmaceutical Industries, Ltd. | Ophthalmic pranoprofen compositions |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1403487A (en) * | 1972-07-21 | 1975-08-28 | Yoshitomi Pharmaceutical | Heterocyclic substituted alkanoic acids and derivatives |
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| US4565851A (en) * | 1983-04-25 | 1986-01-21 | Eastman Kodak Company | Containers having improved gas barrier properties |
| US4525348A (en) * | 1983-12-19 | 1985-06-25 | Yoshitomi Pharmaceutical Industries, Ltd. | Pranoprofen gelled ointment |
| US4940728A (en) * | 1985-05-17 | 1990-07-10 | Postley John E | Treatment for sino-nasal congestion |
| US5110492A (en) * | 1985-05-24 | 1992-05-05 | Irene Casey | Cleaner and disinfectant with dye |
| US5032392A (en) * | 1986-09-04 | 1991-07-16 | Vision Pharmaceuticals | Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| US5414011A (en) * | 1987-09-11 | 1995-05-09 | Syntex (U.S.A.) Inc. | Preservative system for ophthalmic formulations |
| AU634358B2 (en) * | 1990-03-02 | 1993-02-18 | Shiseido Company Ltd. | Oil-in-water emulsion composition containing nonsteroidal antiphlogistic analgesic |
| TW206918B (zh) * | 1991-05-11 | 1993-06-01 | Kuko Seiyaku Kk | |
| JPH05124092A (ja) * | 1991-11-06 | 1993-05-21 | Chisso Corp | ポリオレフイン系樹脂製中空容器 |
| US5693337A (en) * | 1994-07-13 | 1997-12-02 | Wakamoto Pharmaceutical Co., Ltd. | Stable lipid emulsion |
-
1995
- 1995-03-14 LT LT95-028A patent/LT3969B/lt not_active IP Right Cessation
- 1995-03-14 CN CN95114803A patent/CN1091597C/zh not_active Expired - Fee Related
- 1995-03-14 CA CA002144591A patent/CA2144591A1/en not_active Abandoned
- 1995-03-14 EP EP95103625A patent/EP0672414B1/en not_active Expired - Lifetime
- 1995-03-14 PL PL95307671A patent/PL179534B1/pl unknown
- 1995-03-14 LV LVP-95-50A patent/LV10922B/en unknown
- 1995-03-14 HU HU9500772A patent/HUT71245A/hu unknown
- 1995-03-14 NO NO950970A patent/NO950970L/no unknown
- 1995-03-14 FI FI951190A patent/FI951190L/fi unknown
- 1995-03-14 KR KR1019950005273A patent/KR100338851B1/ko not_active Expired - Lifetime
- 1995-03-14 TW TW084102389A patent/TW358812B/zh active
- 1995-03-14 AT AT95103625T patent/ATE297206T1/de not_active IP Right Cessation
- 1995-03-14 DE DE69534258T patent/DE69534258T2/de not_active Expired - Lifetime
- 1995-03-14 EP EP01120068A patent/EP1163906A3/en not_active Withdrawn
- 1995-03-14 ES ES95103625T patent/ES2240966T3/es not_active Expired - Lifetime
- 1995-03-14 RU RU95103893A patent/RU2148402C1/ru active
- 1995-03-15 BR BR9501081A patent/BR9501081A/pt not_active Application Discontinuation
- 1995-03-15 AU AU14852/95A patent/AU707119B2/en not_active Ceased
- 1995-03-15 EE EE9500015A patent/EE9500015A/xx unknown
-
1997
- 1997-01-07 US US08/779,604 patent/US5856345A/en not_active Expired - Fee Related
- 1997-06-12 US US08/873,924 patent/US5889030A/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931295A (en) | 1974-07-23 | 1976-01-06 | Universal Oil Products Company | Hydroxylation of aromatic compounds |
| US4607038A (en) | 1984-03-01 | 1986-08-19 | Yoshitomi Pharmaceutical Industries, Ltd. | Ophthalmic pranoprofen compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0672414A2 (en) | 1995-09-20 |
| CN1091597C (zh) | 2002-10-02 |
| LV10922B (en) | 1996-08-20 |
| NO950970D0 (no) | 1995-03-14 |
| US5889030A (en) | 1999-03-30 |
| HU9500772D0 (en) | 1995-04-28 |
| FI951190A7 (fi) | 1995-09-16 |
| PL179534B1 (pl) | 2000-09-29 |
| FI951190A0 (fi) | 1995-03-14 |
| ATE297206T1 (de) | 2005-06-15 |
| BR9501081A (pt) | 1996-06-04 |
| TW358812B (en) | 1999-05-21 |
| EE9500015A (et) | 1995-12-15 |
| EP0672414A3 (en) | 1995-12-13 |
| AU1485295A (en) | 1995-09-21 |
| ES2240966T3 (es) | 2005-10-16 |
| DE69534258T2 (de) | 2006-05-04 |
| CA2144591A1 (en) | 1995-09-16 |
| KR100338851B1 (ko) | 2002-10-12 |
| HUT71245A (en) | 1995-11-28 |
| EP1163906A2 (en) | 2001-12-19 |
| RU2148402C1 (ru) | 2000-05-10 |
| CN1111510A (zh) | 1995-11-15 |
| LT95028A (en) | 1995-10-25 |
| LV10922A (lv) | 1995-12-20 |
| PL307671A1 (en) | 1995-09-18 |
| DE69534258D1 (de) | 2005-07-14 |
| US5856345A (en) | 1999-01-05 |
| EP1163906A3 (en) | 2003-05-21 |
| FI951190L (fi) | 1995-09-16 |
| EP0672414B1 (en) | 2005-06-08 |
| KR950032201A (ko) | 1995-12-20 |
| NO950970L (no) | 1995-09-18 |
| AU707119B2 (en) | 1999-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 20000314 |