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LT3730608T - Į naviką įsiskverbiančių limfocitų gamybos būdai ir jų panaudojimas imunoterapijoje - Google Patents

Į naviką įsiskverbiančių limfocitų gamybos būdai ir jų panaudojimas imunoterapijoje

Info

Publication number
LT3730608T
LT3730608T LTEP20161179.5T LT20161179T LT3730608T LT 3730608 T LT3730608 T LT 3730608T LT 20161179 T LT20161179 T LT 20161179T LT 3730608 T LT3730608 T LT 3730608T
Authority
LT
Lithuania
Prior art keywords
infiltering
immunotherapy
lymphocytes
tumor
production
Prior art date
Application number
LTEP20161179.5T
Other languages
English (en)
Inventor
Seth Wardell
James Bender
Michael LOTZE
Original Assignee
Iovance Biotherapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61569356&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3730608(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Iovance Biotherapeutics, Inc. filed Critical Iovance Biotherapeutics, Inc.
Publication of LT3730608T publication Critical patent/LT3730608T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
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    • A—HUMAN NECESSITIES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2501/2315—Interleukin-15 (IL-15)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/30—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cancer cells, e.g. reversion of tumour cells

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  • General Engineering & Computer Science (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Molecular Biology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Dermatology (AREA)
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  • Environmental Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
LTEP20161179.5T 2017-03-29 2018-01-05 Į naviką įsiskverbiančių limfocitų gamybos būdai ir jų panaudojimas imunoterapijoje LT3730608T (lt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762478506P 2017-03-29 2017-03-29
US201762539410P 2017-07-31 2017-07-31
US201762548306P 2017-08-21 2017-08-21
US201762554538P 2017-09-05 2017-09-05
US201762559374P 2017-09-15 2017-09-15
US201762567121P 2017-10-02 2017-10-02
US201762577655P 2017-10-26 2017-10-26
US201762582874P 2017-11-07 2017-11-07
US201762596374P 2017-12-08 2017-12-08

Publications (1)

Publication Number Publication Date
LT3730608T true LT3730608T (lt) 2024-12-27

Family

ID=61569356

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP18709132.7T LT3601533T (lt) 2017-03-29 2018-01-05 Į naviką infiltruojamų limfocitų gavimo būdas ir jų panaudojimas imunoterapijai
LTEP20161276.9T LT3722415T (lt) 2017-03-29 2018-01-05 Navikus infiltruojančių limfocitų gamybos procesai ir jų panaudojimas imunoterapijoje
LTEP20161179.5T LT3730608T (lt) 2017-03-29 2018-01-05 Į naviką įsiskverbiančių limfocitų gamybos būdai ir jų panaudojimas imunoterapijoje

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LTEP18709132.7T LT3601533T (lt) 2017-03-29 2018-01-05 Į naviką infiltruojamų limfocitų gavimo būdas ir jų panaudojimas imunoterapijai
LTEP20161276.9T LT3722415T (lt) 2017-03-29 2018-01-05 Navikus infiltruojančių limfocitų gamybos procesai ir jų panaudojimas imunoterapijoje

Country Status (36)

Country Link
US (60) US10894063B2 (lt)
EP (6) EP3766964A1 (lt)
JP (6) JP7169291B2 (lt)
KR (2) KR102686794B1 (lt)
CN (1) CN110785486A (lt)
AU (2) AU2018243355B2 (lt)
BR (1) BR112019020326A2 (lt)
CA (1) CA3057975A1 (lt)
CL (2) CL2019002769A1 (lt)
CO (1) CO2019011995A2 (lt)
CR (1) CR20190487A (lt)
CY (1) CY1124136T1 (lt)
DK (3) DK3730608T3 (lt)
EC (1) ECSP19077884A (lt)
ES (3) ES3009885T3 (lt)
FI (2) FI3730608T3 (lt)
HR (3) HRP20210677T1 (lt)
HU (3) HUE054829T2 (lt)
IL (2) IL305198A (lt)
JO (1) JOP20190224A1 (lt)
LT (3) LT3601533T (lt)
MA (2) MA68856B1 (lt)
MD (3) MD3722415T2 (lt)
MX (2) MX2019011768A (lt)
NZ (1) NZ796142A (lt)
PE (1) PE20191841A1 (lt)
PH (1) PH12019502247A1 (lt)
PL (3) PL3722415T3 (lt)
PT (3) PT3722415T (lt)
RS (3) RS66400B1 (lt)
SG (1) SG11201908994RA (lt)
SI (3) SI3601533T1 (lt)
SM (3) SMT202100298T1 (lt)
TN (1) TN2019000273A1 (lt)
TW (1) TWI799402B (lt)
WO (1) WO2018182817A1 (lt)

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US9844569B2 (en) 2013-03-01 2017-12-19 The United State Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of producing enriched populations of tumor reactive T cells from peripheral blood
GB201522097D0 (en) 2015-12-15 2016-01-27 Cellular Therapeutics Ltd Cells
MX2019004707A (es) 2016-10-26 2019-08-12 Iovance Biotherapeutics Inc Reestimulacion de linfocitos infiltrantes de tumor crioconservados.
US11332713B2 (en) 2016-11-16 2022-05-17 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
WO2018129336A1 (en) 2017-01-06 2018-07-12 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
JP7165717B2 (ja) 2017-03-15 2022-11-04 パンディオン・オペレーションズ・インコーポレイテッド 標的免疫寛容
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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