LT1991522T - Deuterinti katecholamino dariniai ir minėtų junginių turintys vaistai - Google Patents

Deuterinti katecholamino dariniai ir minėtų junginių turintys vaistai

Info

Publication number: LT1991522T
Authority: LT; Lithuania
Prior art keywords: medicaments; compounds; catecholamine derivatives; deuterated catecholamine; deuterated
Prior art date: 2006-02-17

Application number

LTEP07703542.6T

Other languages

English (en)

Inventor

Rudolf-Giesbert Alken

Frank Schneider

Original Assignee

Ratiopharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-17

Filing date

2007-02-16

Publication date

2016-09-26

2007-02-16 Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh

2016-09-26 Publication of LT1991522T publication Critical patent/LT1991522T/lt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychology (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

LTEP07703542.6T 2006-02-17 2007-02-16 Deuterinti katecholamino dariniai ir minėtų junginių turintys vaistai LT1991522T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102006008316		2006-02-17
PCT/EP2007/001555 WO2007093450A2 (en)	2006-02-17	2007-02-16	Deuterated catecholamine derivatives and medicaments comprising said compounds

Publications (1)

Publication Number	Publication Date
LT1991522T true LT1991522T (lt)	2016-09-26

Family

ID=38236462

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP07703542.6T LT1991522T (lt)	2006-02-17	2007-02-16	Deuterinti katecholamino dariniai ir minėtų junginių turintys vaistai

Country Status (24)

Country	Link
US (2)	USRE46555E1 (lt)
EP (2)	EP3101001B1 (lt)
JP (1)	JP5248331B2 (lt)
KR (1)	KR101411422B1 (lt)
CN (1)	CN101384545B (lt)
AU (1)	AU2007214622B2 (lt)
BR (1)	BRPI0708071A8 (lt)
CA (1)	CA2642593C (lt)
CY (1)	CY1117995T1 (lt)
DK (1)	DK1991522T3 (lt)
EA (1)	EA017983B1 (lt)
ES (1)	ES2587368T3 (lt)
HR (1)	HRP20161039T1 (lt)
HU (1)	HUE028777T2 (lt)
IL (1)	IL193102A (lt)
LT (1)	LT1991522T (lt)
ME (1)	ME02508B (lt)
PL (1)	PL1991522T3 (lt)
PT (1)	PT1991522T (lt)
RS (1)	RS55142B1 (lt)
SI (1)	SI1991522T1 (lt)
UA (1)	UA97795C2 (lt)
WO (1)	WO2007093450A2 (lt)
ZA (1)	ZA200806568B (lt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
NO2303330T3 (lt)	2008-06-06	2018-04-14
RU2509773C2 (ru)	2008-07-15	2014-03-20	Теракос, Инк.	Дейтерированные бензилбензольные производные и способы применения
JP6117249B2 (ja)	2012-02-28	2017-04-19	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形
CN104684555A (zh)	2012-09-18	2015-06-03	奥斯拜客斯制药有限公司	囊泡单胺转运体2的氘化苯并喹啉抑制剂的制剂药代动力学
US9550780B2 (en)	2012-09-18	2017-01-24	Auspex Pharmaceuticals, Inc.	Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
US9763904B2 (en)	2013-02-05	2017-09-19	Teva Pharmaceuticals International Gmbh	Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds
WO2014122184A1 (en)	2013-02-05	2014-08-14	Cdrd Berolina Ab	Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds
WO2014174425A2 (en) *	2013-04-24	2014-10-30	Mahesh Kandula	Compositions and methods for the treatment of orthostasis and neurological diseases
EA201600093A1 (ru) *	2013-07-08	2016-08-31	Ауспекс Фармасьютикалс, Инк.	Дигидроксифенильные нейромедиаторные соединения, композиции и способы
MX2016006622A (es) *	2013-11-22	2016-12-09	Auspex Pharmaceuticals Inc	Metodos para tratar actividad muscular anormal.
AU2014357518A1 (en)	2013-12-03	2016-06-09	Auspex Pharmaceuticals, Inc.	Methods of manufacturing benzoquinoline compounds
KR20160117596A (ko)	2014-02-07	2016-10-10	오스펙스 파마슈티칼스, 인코포레이티드	신규 제약 제제
EP2918266A1 (en)	2014-03-11	2015-09-16	CDRD Berolina AB	Composition comprising a dopamine agonist and an L-DOPA derivative for treating Parkinson's disease
GB201420341D0 (en) *	2014-11-17	2014-12-31	Evolution Valves Ltd	Valve arrangement
PL3265085T3 (pl)	2015-03-06	2022-11-07	Auspex Pharmaceuticals, Inc.	Sposoby leczenia zaburzeń związanych z nieprawidłowymi ruchami mimowolnymi
CN106343013A (zh) *	2015-07-19	2017-01-25	中国科学院上海有机化学研究所	一种粮食储存方法
CN105360267B (zh) *	2015-10-09	2017-11-10	青岛振坤食品机械有限公司	一种全自动穿串机
BR112018007118A2 (pt)	2015-10-09	2018-12-11	Teva Pharmaceuticals Int Gmbh	método para tratar um distúrbio de deficiência de dopamina, método para melhorar o tempo motor ativo sem discinesia num paciente com doença de parkinson, método para reduzir discinesia num indivíduo com um distúrbio de deficiência de dopamina, método para reduzir o tempo motor inativo num indivíduo com um distúrbio de deficiência de dopamina, método para reduzir flutuações de nível de dopamina estriatal num indivíduo com um distúrbio de deficiência de dopamina, método para reduzir discinesia num indivíduo com um distúrbio de deficiência de dopamina após um tratamento de longo prazo, composição farmacêutica e embalagem
CN105862897B (zh) *	2016-04-11	2018-01-16	江苏省华建建设股份有限公司	砂质泥岩地基浅基础原槽浇筑施工工法
EP3849533A4 (en)	2018-09-13	2022-06-22	University of Canberra	Methods of inhibition
AU2019392924A1 (en) *	2018-12-06	2021-06-17	Senda Biosciences, Inc	Quaternary ammonium salts as inhibitors of trimethylamine production

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3699158A (en)	1969-08-25	1972-10-17	Merck & Co Inc	Selective deuteration of tyrosine, aspartic and glutamic acids
DE2049807A1 (en)	1970-10-10	1972-04-13	Hartmeyer H	Conversion of closed cell plastics foam to - open cell structure
DE2049115C3 (de)	1970-10-06	1981-07-30	Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo	Verwendung von Calcium-5-butylpicolinat und/oder Calcium-5-pentylpicolinat bei der Bekämpfung des Parkinsonismus mit 3-(3,4-Dihydroxyphenyl)-L-alanin (L-Dopa)
DE252290T1 (de) *	1986-06-10	1988-06-09	Chiesi Farmaceutici S.P.A., Parma	Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
IT1226902B (it)	1988-07-12	1991-02-21	Mini Ricerca Scient Tecnolog	Processo per la sintesi del levodopa
US5354885A (en) *	1992-12-24	1994-10-11	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Process for preparing ethyl ester of L-DOPA
US6221335B1 (en) *	1994-03-25	2001-04-24	Isotechnika, Inc.	Method of using deuterated calcium channel blockers
US6440710B1 (en) *	1998-12-10	2002-08-27	The Scripps Research Institute	Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds
PT1104760E (pt) *	1999-12-03	2003-06-30	Pfizer Prod Inc	Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios
DE10261807A1 (de) *	2002-12-19	2004-07-01	Turicum Drug Development Ag	Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
DE10261808A1 (de)	2002-12-19	2004-07-08	Turicum Drug Development Ag	Verwendung von L-DOPA, seiner Derivate und diese Verbindungen enthaltender Arzneimittel zur Prophylaxe psychotischer Erkrankungen

2007
- 2007-02-16 UA UAA200811184A patent/UA97795C2/uk unknown
- 2007-02-16 BR BRPI0708071A patent/BRPI0708071A8/pt not_active Application Discontinuation
- 2007-02-16 CN CN200780005912.6A patent/CN101384545B/zh not_active Expired - Fee Related
- 2007-02-16 HU HUE07703542A patent/HUE028777T2/en unknown
- 2007-02-16 AU AU2007214622A patent/AU2007214622B2/en not_active Ceased
- 2007-02-16 EP EP16170031.5A patent/EP3101001B1/en not_active Not-in-force
- 2007-02-16 RS RS20160674A patent/RS55142B1/sr unknown
- 2007-02-16 SI SI200731819A patent/SI1991522T1/sl unknown
- 2007-02-16 PL PL07703542T patent/PL1991522T3/pl unknown
- 2007-02-16 LT LTEP07703542.6T patent/LT1991522T/lt unknown
- 2007-02-16 KR KR1020087022011A patent/KR101411422B1/ko not_active Expired - Fee Related
- 2007-02-16 ME MEP-2016-167A patent/ME02508B/me unknown
- 2007-02-16 JP JP2008554702A patent/JP5248331B2/ja not_active Expired - Fee Related
- 2007-02-16 EP EP07703542.6A patent/EP1991522B1/en active Active
- 2007-02-16 HR HRP20161039TT patent/HRP20161039T1/hr unknown
- 2007-02-16 EA EA200801826A patent/EA017983B1/ru not_active IP Right Cessation
- 2007-02-16 US US14/464,568 patent/USRE46555E1/en not_active Expired - Fee Related
- 2007-02-16 ES ES07703542.6T patent/ES2587368T3/es active Active
- 2007-02-16 US US12/224,120 patent/US8247603B2/en not_active Ceased
- 2007-02-16 CA CA2642593A patent/CA2642593C/en active Active
- 2007-02-16 DK DK07703542.6T patent/DK1991522T3/en active
- 2007-02-16 PT PT77035426T patent/PT1991522T/pt unknown
- 2007-02-16 WO PCT/EP2007/001555 patent/WO2007093450A2/en not_active Ceased
2008
- 2008-07-28 ZA ZA200806568A patent/ZA200806568B/xx unknown
- 2008-07-29 IL IL193102A patent/IL193102A/en active IP Right Grant
2016
- 2016-08-17 CY CY20161100808T patent/CY1117995T1/el unknown

Also Published As

Publication number	Publication date
JP2009526799A (ja)	2009-07-23
BRPI0708071A2 (pt)	2011-05-17
EP3101001B1 (en)	2020-04-01
EA017983B1 (ru)	2013-04-30
KR20080106539A (ko)	2008-12-08
EA200801826A1 (ru)	2009-02-27
AU2007214622B2 (en)	2012-02-23
HRP20161039T1 (hr)	2016-11-04
DK1991522T3 (en)	2016-08-29
CN101384545B (zh)	2014-09-03
BRPI0708071A8 (pt)	2017-12-26
ES2587368T3 (es)	2016-10-24
PT1991522T (pt)	2016-08-23
RS55142B1 (sr)	2016-12-30
CA2642593A1 (en)	2007-08-23
US20090018191A1 (en)	2009-01-15
CA2642593C (en)	2014-11-04
WO2007093450A2 (en)	2007-08-23
IL193102A0 (en)	2009-02-11
EP1991522A2 (en)	2008-11-19
EP3101001A1 (en)	2016-12-07
PL1991522T3 (pl)	2017-07-31
US8247603B2 (en)	2012-08-21
ZA200806568B (en)	2009-07-29
WO2007093450A3 (en)	2007-09-27
USRE46555E1 (en)	2017-09-19
SI1991522T1 (sl)	2016-10-28
AU2007214622A1 (en)	2007-08-23
ME02508B (me)	2017-06-20
KR101411422B1 (ko)	2014-07-03
HUE028777T2 (en)	2017-01-30
JP5248331B2 (ja)	2013-07-31
EP1991522B1 (en)	2016-05-18
UA97795C2 (uk)	2012-03-26
CN101384545A (zh)	2009-03-11
CY1117995T1 (el)	2017-05-17
IL193102A (en)	2015-01-29

Publication	Publication Date	Title
ZA200806568B (en)	2009-07-29	Deuterated catecholamine derivatives and medicaments comprising said compounds
IL192565A0 (en)	2009-08-03	Medicament for topical use
GB0625659D0 (en)	2007-01-31	Therapeutic compounds and their use
IL194095A0 (en)	2009-08-03	Drug microparticles
ZA201000185B (en)	2011-03-30	17beta-cyano-18a-homo-19-nor-androst-4-ene derivative,use thereof and medicaments containing said derivative
IL194751A0 (en)	2009-08-03	Drugs and uses
ZA200809393B (en)	2009-12-30	Treatments using citrulline
IL196493A0 (en)	2009-11-18	Medication applicator device
IL197767A0 (en)	2009-12-24	Capecitabine pediatric tablets
EP2077262A4 (en)	2011-12-28	IMINOPYRIDINE DERIVATIVE AND USE THEREOF
IL195639A0 (en)	2009-09-01	Tricyclic compound and pharmaceutical use thereof
EP2070919A4 (en)	2010-05-05	SPIROCHINONE COMPOUND AND PHARMACEUTICAL COMPOSITION
GB0614586D0 (en)	2006-08-30	Pharmaceutical Formulation
IL197883A0 (en)	2009-12-24	Combination drug
ZA201000187B (en)	2011-03-30	17b-cyano-19-nor-androst-4-ene derivative,use thereof and medicaments containing said derivative
IL199178A0 (en)	2010-03-28	Aminoalcohol derivatives and their therapeutic use
GB0625783D0 (en)	2007-02-07	Medicament
ZA201000186B (en)	2011-03-30	17b-cyano-19-androst-4-ene derivative,use thereof and medicaments containing said derivative
EP2114404A4 (en)	2010-03-03	COMPOUND AND PHARMACEUTICAL COMPOSITION
IL191892A0 (en)	2008-12-29	2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
GB0613031D0 (en)	2006-08-09	Medicaments
GB0615064D0 (en)	2006-09-06	Medicament
HK1124308A (en)	2009-07-10	Deuterated catecholamine derivatives and medicaments comprising said compounds
GB0615814D0 (en)	2006-09-20	Medicament
ZA200708369B (en)	2009-08-26	Medicament