KR950700903A - 5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists) - Google Patents

5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists)

Info

Publication number: KR950700903A
Authority: KR; South Korea
Prior art keywords: aryl; alkyl; alkylaryl; hydrogen; pct
Prior art date: 1992-04-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

KR1019940703551A

Other languages

English (en)

Other versions

KR0179074B1 (ko

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-10

Filing date

1994-10-07

Publication date

1995-02-20

1993-03-04 Application filed filed Critical

1995-02-20 Publication of KR950700903A publication Critical patent/KR950700903A/ko

1999-03-20 Application granted granted Critical

1999-03-20 Publication of KR0179074B1 publication Critical patent/KR0179074B1/ko

2013-03-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Obesity (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
Materials For Photolithography (AREA)
Soft Magnetic Materials (AREA)
Pyrrole Compounds (AREA)

KR1019940703551A 1992-04-10 1993-03-04 5-ht1 작용물질로서의 아실아미노인돌 유도체 Expired - Fee Related KR0179074B1 (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US86638292A	1992-04-10	1992-04-10
US7/866382		1992-04-10
PCT/US1993/001807 WO1993021180A1 (en)	1992-04-10	1993-03-04	Acylaminoindole derivatives as 5-ht1 agonists

Publications (2)

Publication Number	Publication Date
KR950700903A true KR950700903A (ko)	1995-02-20
KR0179074B1 KR0179074B1 (ko)	1999-03-20

Family

ID=25347493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019940703551A Expired - Fee Related KR0179074B1 (ko)	1992-04-10	1993-03-04	5-ht1 작용물질로서의 아실아미노인돌 유도체

Country Status (31)

Country	Link
US (1)	US5498626A (ko)
EP (1)	EP0635015B1 (ko)
JP (1)	JP2544704B2 (ko)
KR (1)	KR0179074B1 (ko)
CN (1)	CN1038506C (ko)
AT (1)	ATE148465T1 (ko)
AU (1)	AU670270B2 (ko)
BR (1)	BR9306221A (ko)
CA (1)	CA2132706C (ko)
CZ (1)	CZ282653B6 (ko)
DE (1)	DE69307875T2 (ko)
DK (1)	DK0635015T3 (ko)
EG (1)	EG20466A (ko)
ES (1)	ES2097496T3 (ko)
FI (2)	FI111256B (ko)
GR (1)	GR3022767T3 (ko)
HR (1)	HRP930753B1 (ko)
HU (1)	HUT64060A (ko)
IL (1)	IL105309A0 (ko)
MX (1)	MX9301996A (ko)
MY (1)	MY115278A (ko)
NO (1)	NO309860B1 (ko)
NZ (1)	NZ251047A (ko)
PL (1)	PL172232B1 (ko)
RU (1)	RU2110516C1 (ko)
SK (1)	SK278182B6 (ko)
TW (1)	TW394769B (ko)
UA (1)	UA34452C2 (ko)
WO (1)	WO1993021180A1 (ko)
YU (1)	YU48916B (ko)
ZA (1)	ZA932536B (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
RU2101283C1 (ru)	1992-04-07	1998-01-10	Пфайзер Инк.	Производные индола или их фармацевтически приемлемые соли
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
ES2070772B1 (es) *	1993-08-09	1996-02-16	Pfizer	Derivados de acilaminoindol
AU686654B2 (en) *	1993-08-31	1998-02-12	Pfizer Inc.	5-arylindole derivatives
GB9402011D0 (en) *	1994-02-02	1994-03-30	Merck Sharp & Dohme	Therapeutic agents
GB9402016D0 (en) *	1994-02-02	1994-03-30	Merck Sharp & Dohme	Therapeutic agents
FI971334A7 (fi) *	1994-08-03	1997-04-01	Asta Medica Ag	Indoli-, indatsoli-, pyridopyrroli- ja pyridopyratsolijohdannaiset, jo illa on antiastmaattinen, antiallerginen, anti-inflammatorinen ja immu nomoduloiva vaikutus
GB9417310D0 (en)	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
GB9420503D0 (en) *	1994-10-11	1994-11-23	Pfizer Ltd	Therapeutic agents
GB9420529D0 (en)	1994-10-12	1994-11-30	Pfizer Ltd	Indoles
WO1999053956A1 (en) *	1998-04-16	1999-10-28	Yamanouchi Pharmaceutical Co., Ltd.	Remedies for obesity
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
CA2514024A1 (en) *	2003-01-22	2004-08-05	Gtx Inc.	Treating androgen deficiency in female (adif)-associated conditions with sarms
CA2708043C (en) *	2007-12-07	2012-11-13	Pfizer Inc.	Tosylate salt of trans-n-isobutyl-3-fluoro-3- [3-fluoro-4- (pyrrolidin-1-yl-methyl) -phenyl] cyclobut anecarboxamide
HK1215170A1 (zh)	2012-11-14	2016-08-19	The Johns Hopkins University	治療精神分裂症的方法和組合物
CN103408535B (zh) *	2013-08-13	2016-03-02	张家港威胜生物医药有限公司	一种依来曲普坦中间体-5-溴-3-(n-甲基吡咯啉-2-基甲基)-1h-吲哚合成工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
NZ197998A (en) *	1980-08-12	1985-08-16	Glaxo Group Ltd	5-amino(methyl)-1h-indol-3-ylalkaneamines
BE889931A (fr) *	1980-08-12	1982-02-11	Glaxo Group Ltd	Derives indoliques, leur preparation et leurs applications en tant que medicaments
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en) *	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en) *	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) *	1990-05-15	1991-11-16	Jacques Chauveau	Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
PT97888B (pt) *	1990-06-07	1998-12-31	Zeneca Ltd	Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
CA2091562C (en) *	1990-10-15	2001-03-27	John Eugene Macor	Indole derivatives useful in psychotherapeutics
US5208248A (en) *	1991-01-11	1993-05-04	Merck Sharpe & Dohme, Ltd.	Indazole-substituted five-membered heteroaromatic compounds
SK278998B6 (sk) *	1991-02-01	1998-05-06	Merck Sharp & Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu, spôsob i
WO1993011106A1 (en) *	1991-11-25	1993-06-10	Pfizer, Inc.	Indole derivatives

1993
- 1993-03-04 DK DK93907096.7T patent/DK0635015T3/da active
- 1993-03-04 CA CA002132706A patent/CA2132706C/en not_active Expired - Fee Related
- 1993-03-04 NZ NZ251047A patent/NZ251047A/en unknown
- 1993-03-04 ES ES93907096T patent/ES2097496T3/es not_active Expired - Lifetime
- 1993-03-04 JP JP5518302A patent/JP2544704B2/ja not_active Expired - Fee Related
- 1993-03-04 AT AT93907096T patent/ATE148465T1/de not_active IP Right Cessation
- 1993-03-04 UA UA94105907A patent/UA34452C2/uk unknown
- 1993-03-04 SK SK1207-94A patent/SK278182B6/sk unknown
- 1993-03-04 EP EP93907096A patent/EP0635015B1/en not_active Expired - Lifetime
- 1993-03-04 DE DE69307875T patent/DE69307875T2/de not_active Expired - Fee Related
- 1993-03-04 CZ CZ942477A patent/CZ282653B6/cs not_active IP Right Cessation
- 1993-03-04 PL PL93305558A patent/PL172232B1/pl not_active IP Right Cessation
- 1993-03-04 KR KR1019940703551A patent/KR0179074B1/ko not_active Expired - Fee Related
- 1993-03-04 WO PCT/US1993/001807 patent/WO1993021180A1/en not_active Ceased
- 1993-03-04 RU RU94045902/04A patent/RU2110516C1/ru not_active IP Right Cessation
- 1993-03-04 BR BR9306221A patent/BR9306221A/pt not_active Application Discontinuation
- 1993-03-04 AU AU37821/93A patent/AU670270B2/en not_active Ceased
- 1993-03-04 US US08/295,792 patent/US5498626A/en not_active Expired - Fee Related
- 1993-03-09 TW TW082101732A patent/TW394769B/zh active
- 1993-04-02 HR HR930753A patent/HRP930753B1/xx not_active IP Right Cessation
- 1993-04-05 IL IL105309A patent/IL105309A0/xx not_active IP Right Cessation
- 1993-04-06 MX MX9301996A patent/MX9301996A/es unknown
- 1993-04-07 EG EG21493A patent/EG20466A/xx active
- 1993-04-08 FI FI931613A patent/FI111256B/fi not_active IP Right Cessation
- 1993-04-08 ZA ZA932536A patent/ZA932536B/xx unknown
- 1993-04-08 MY MYPI93000646A patent/MY115278A/en unknown
- 1993-04-09 HU HU9301048A patent/HUT64060A/hu unknown
- 1993-04-09 YU YU25593A patent/YU48916B/sh unknown
- 1993-04-09 CN CN93104439A patent/CN1038506C/zh not_active Expired - Fee Related
1994
- 1994-10-07 NO NO943803A patent/NO309860B1/no not_active IP Right Cessation
1997
- 1997-03-07 GR GR970400451T patent/GR3022767T3/el unknown
2001
- 2001-02-05 FI FI20010214A patent/FI20010214A7/fi unknown

Also Published As

Publication number	Publication date
KR0179074B1 (ko)	1999-03-20
CA2132706A1 (en)	1993-10-28
EP0635015B1 (en)	1997-01-29
JP2544704B2 (ja)	1996-10-16
MX9301996A (es)	1994-03-31
JPH07501831A (ja)	1995-02-23
MY115278A (en)	2003-05-31
CZ247794A3 (en)	1995-07-12
DE69307875D1 (de)	1997-03-13
FI931613A0 (fi)	1993-04-08
FI20010214L (fi)	2001-02-05
WO1993021180A1 (en)	1993-10-28
BR9306221A (pt)	1998-06-30
CA2132706C (en)	1998-08-04
AU3782193A (en)	1993-11-18
IL105309A0 (en)	1993-08-18
UA34452C2 (uk)	2001-03-15
CZ282653B6 (cs)	1997-08-13
ATE148465T1 (de)	1997-02-15
CN1080288A (zh)	1994-01-05
ES2097496T3 (es)	1997-04-01
NO943803L (no)	1994-10-07
HRP930753A2 (en)	1994-10-31
NO943803D0 (no)	1994-10-07
RU2110516C1 (ru)	1998-05-10
CN1038506C (zh)	1998-05-27
DK0635015T3 (da)	1997-03-17
RU94045902A (ru)	1996-08-27
PL172232B1 (pl)	1997-08-29
EP0635015A1 (en)	1995-01-25
HRP930753B1 (en)	2000-10-31
SK120794A3 (en)	1995-05-10
US5498626A (en)	1996-03-12
FI20010214A7 (fi)	2001-02-05
SK278182B6 (en)	1996-03-06
GR3022767T3 (en)	1997-06-30
ZA932536B (en)	1994-10-08
TW394769B (en)	2000-06-21
HU9301048D0 (en)	1993-06-28
FI111256B (fi)	2003-06-30
DE69307875T2 (de)	1997-05-22
NO309860B1 (no)	2001-04-09
YU48916B (sh)	2002-11-15
YU25593A (sh)	1996-10-09
FI931613L (fi)	1993-10-11
AU670270B2 (en)	1996-07-11
NZ251047A (en)	1996-09-25
EG20466A (en)	1999-05-31
HUT64060A (en)	1993-11-29

Publication	Publication Date	Title
KR950700903A (ko)	1995-02-20	5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists)
FI942395A0 (fi)	1994-05-24	Indolijohdannaiset
MY108909A (en)	1996-11-30	Indole derivatives
MY111683A (en)	2000-11-30	Indole derivatives.
ATE170836T1 (de)	1998-09-15	5-arylindolderivate
CA2117643A1 (en)	1993-09-16	Indole Derivatives

Legal Events

Date	Code	Title	Description
1994-10-07	A201	Request for examination
1994-10-07	PA0105	International application	St.27 status event code: A-0-1-A10-A15-nap-PA0105
1994-10-07	PA0201	Request for examination	St.27 status event code: A-1-2-D10-D11-exm-PA0201
1994-10-07	R17-X000	Change to representative recorded	St.27 status event code: A-3-3-R10-R17-oth-X000
1995-02-20	PG1501	Laying open of application	St.27 status event code: A-1-1-Q10-Q12-nap-PG1501
1997-11-24	E902	Notification of reason for refusal
1997-11-24	PE0902	Notice of grounds for rejection	St.27 status event code: A-1-2-D10-D21-exm-PE0902
1998-01-23	AMND	Amendment
1998-01-23	P11-X000	Amendment of application requested	St.27 status event code: A-2-2-P10-P11-nap-X000
1998-01-23	R17-X000	Change to representative recorded	St.27 status event code: A-3-3-R10-R17-oth-X000
1998-02-17	E801	Decision on dismissal of amendment
1998-06-15	J121	Written withdrawal of request for trial
1998-06-15	PJ1201	Withdrawal of trial	St.27 status event code: A-3-3-V10-V13-apl-PJ1201
1998-07-22	E601	Decision to refuse application
1998-07-22	PE0601	Decision on rejection of patent	St.27 status event code: N-2-6-B10-B15-exm-PE0601
1998-08-28	J201	Request for trial against refusal decision
1998-08-28	PJ0201	Trial against decision of rejection	St.27 status event code: A-3-3-V10-V11-apl-PJ0201
1998-09-12	PB0901	Examination by re-examination before a trial	St.27 status event code: A-6-3-E10-E12-rex-PB0901
1998-09-30	B701	Decision to grant
1998-09-30	PB0701	Decision of registration after re-examination before a trial	St.27 status event code: A-3-4-F10-F13-rex-PB0701
1998-11-26	GRNT	Written decision to grant
1998-11-26	PR0701	Registration of establishment	St.27 status event code: A-2-4-F10-F11-exm-PR0701
1998-11-26	PR1002	Payment of registration fee	St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1
1999-01-27	PN2301	Change of applicant	St.27 status event code: A-5-5-R10-R13-asn-PN2301 St.27 status event code: A-5-5-R10-R11-asn-PN2301
1999-03-20	PG1601	Publication of registration	St.27 status event code: A-4-4-Q10-Q13-nap-PG1601
2001-10-25	PR1001	Payment of annual fee	St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4
2002-10-28	FPAY	Annual fee payment	Payment date: 20021029 Year of fee payment: 5
2002-10-29	PR1001	Payment of annual fee	St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5
2003-11-27	LAPS	Lapse due to unpaid annual fee
2003-11-27	PC1903	Unpaid annual fee	St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20031127 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE
2004-08-10	PC1903	Unpaid annual fee	St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20031127
2016-03-09	R18-X000	Changes to party contact information recorded	St.27 status event code: A-5-5-R10-R18-oth-X000
2018-02-26	P22-X000	Classification modified	St.27 status event code: A-4-4-P10-P22-nap-X000
2023-03-21	R18-X000	Changes to party contact information recorded	St.27 status event code: A-5-5-R10-R18-oth-X000