JPH11504245A - 医薬組成物を別の薬品と混合する装置および方法ならびに医薬製剤の経口投与方法 - Google Patents
医薬組成物を別の薬品と混合する装置および方法ならびに医薬製剤の経口投与方法Info
- Publication number
- JPH11504245A JPH11504245A JP8533227A JP53322796A JPH11504245A JP H11504245 A JPH11504245 A JP H11504245A JP 8533227 A JP8533227 A JP 8533227A JP 53322796 A JP53322796 A JP 53322796A JP H11504245 A JPH11504245 A JP H11504245A
- Authority
- JP
- Japan
- Prior art keywords
- chamber
- hollow body
- plunger
- rod
- wall surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 31
- 229940079593 drug Drugs 0.000 title claims abstract description 26
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 24
- 238000002156 mixing Methods 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 title claims description 21
- 238000007789 sealing Methods 0.000 claims abstract description 31
- 238000004891 communication Methods 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 41
- 238000009472 formulation Methods 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 8
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- 230000004888 barrier function Effects 0.000 claims description 5
- 239000010410 layer Substances 0.000 claims description 5
- 229940126409 proton pump inhibitor Drugs 0.000 claims description 5
- 239000000612 proton pump inhibitor Substances 0.000 claims description 5
- 229960000381 omeprazole Drugs 0.000 claims description 4
- 239000008188 pellet Substances 0.000 claims description 4
- 241001465754 Metazoa Species 0.000 claims description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- 239000002274 desiccant Substances 0.000 claims description 3
- 239000002702 enteric coating Substances 0.000 claims description 3
- 238000009505 enteric coating Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 abstract description 9
- 230000002093 peripheral effect Effects 0.000 abstract description 5
- 239000000463 material Substances 0.000 description 8
- 239000000499 gel Substances 0.000 description 7
- 239000000243 solution Substances 0.000 description 6
- 238000003860 storage Methods 0.000 description 6
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 241000283086 Equidae Species 0.000 description 4
- -1 Preferably Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 229920001971 elastomer Polymers 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000005060 rubber Substances 0.000 description 3
- 230000002411 adverse Effects 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 241000416162 Astragalus gummifer Species 0.000 description 1
- HIZCTWCPHWUPFU-UHFFFAOYSA-N Glycerol tribenzoate Chemical compound C=1C=CC=CC=1C(=O)OCC(OC(=O)C=1C=CC=CC=1)COC(=O)C1=CC=CC=C1 HIZCTWCPHWUPFU-UHFFFAOYSA-N 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 235000020774 essential nutrients Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0015—Devices specially adapted for taking medicines
- A61J7/0038—Straws
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
- B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Package Specialized In Special Use (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9501631A SE504683C2 (sv) | 1995-05-03 | 1995-05-03 | Anordning för att blanda en farmaceutisk komposition med ett annat medel |
| SE9501631-7 | 1995-05-03 | ||
| PCT/SE1996/000527 WO1996034681A1 (en) | 1995-05-03 | 1996-04-23 | Device and process for mixing a pharmaceutical composition with another agent and method for oral administration of the pharmaceutical preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH11504245A true JPH11504245A (ja) | 1999-04-20 |
Family
ID=20398172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8533227A Pending JPH11504245A (ja) | 1995-05-03 | 1996-04-23 | 医薬組成物を別の薬品と混合する装置および方法ならびに医薬製剤の経口投与方法 |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0827419A1 (is) |
| JP (1) | JPH11504245A (is) |
| KR (1) | KR19990008268A (is) |
| CN (1) | CN1183057A (is) |
| AR (1) | AR001841A1 (is) |
| AU (1) | AU700156B2 (is) |
| BR (1) | BR9608271A (is) |
| CA (1) | CA2218739A1 (is) |
| CZ (1) | CZ345697A3 (is) |
| EE (1) | EE9700265A (is) |
| HU (1) | HUP9801947A3 (is) |
| IS (1) | IS4595A (is) |
| NO (1) | NO975019D0 (is) |
| NZ (1) | NZ306603A (is) |
| PL (1) | PL323157A1 (is) |
| SE (1) | SE504683C2 (is) |
| SK (1) | SK142897A3 (is) |
| TR (1) | TR199701288T1 (is) |
| TW (1) | TW341520B (is) |
| WO (1) | WO1996034681A1 (is) |
| ZA (1) | ZA963190B (is) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010523238A (ja) * | 2007-04-10 | 2010-07-15 | サンド アクチエンゲゼルシャフト | 物質の経口投与のための装置 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997011029A2 (en) * | 1995-09-18 | 1997-03-27 | Delta Chemical Corporation | Polyaluminum chlorides and polyaluminum chlorosulfates methods and compositions |
| CO5290346A1 (es) * | 1999-12-03 | 2003-06-27 | Baxter Int | Metodo y aparato para controlar la estrategia de hacer compuestos con mezclas farmaceuticas |
| USD978375S1 (en) | 2013-03-13 | 2023-02-14 | Abbott Laboratories | Reagent container |
| US9535082B2 (en) | 2013-03-13 | 2017-01-03 | Abbott Laboratories | Methods and apparatus to agitate a liquid |
| USD962471S1 (en) | 2013-03-13 | 2022-08-30 | Abbott Laboratories | Reagent container |
| US10058866B2 (en) | 2013-03-13 | 2018-08-28 | Abbott Laboratories | Methods and apparatus to mitigate bubble formation in a liquid |
| WO2025146637A1 (en) * | 2024-01-05 | 2025-07-10 | Orbicular Pharmaceutical Technologies Private Limited | Automated machine and process for manufacturing viscous pharmaceutical compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE462315B (sv) * | 1989-05-03 | 1990-06-11 | Surgitec Ab | Anordning foer tillverkning av bencement |
| DK235589D0 (da) * | 1989-05-12 | 1989-05-12 | Wolff & Kaaber | Fremgangsmaade og indretning til blanding af en fast og en flydende komponent |
-
1995
- 1995-05-03 SE SE9501631A patent/SE504683C2/sv not_active IP Right Cessation
-
1996
- 1996-04-05 TW TW085103956A patent/TW341520B/zh active
- 1996-04-22 ZA ZA963190A patent/ZA963190B/xx unknown
- 1996-04-23 AU AU55203/96A patent/AU700156B2/en not_active Ceased
- 1996-04-23 EP EP96912371A patent/EP0827419A1/en not_active Withdrawn
- 1996-04-23 WO PCT/SE1996/000527 patent/WO1996034681A1/en not_active Ceased
- 1996-04-23 EE EE9700265A patent/EE9700265A/xx unknown
- 1996-04-23 CA CA002218739A patent/CA2218739A1/en not_active Abandoned
- 1996-04-23 KR KR1019970707794A patent/KR19990008268A/ko not_active Withdrawn
- 1996-04-23 SK SK1428-97A patent/SK142897A3/sk unknown
- 1996-04-23 JP JP8533227A patent/JPH11504245A/ja active Pending
- 1996-04-23 PL PL96323157A patent/PL323157A1/xx unknown
- 1996-04-23 CZ CZ973456A patent/CZ345697A3/cs unknown
- 1996-04-23 HU HU9801947A patent/HUP9801947A3/hu unknown
- 1996-04-23 CN CN96193658A patent/CN1183057A/zh active Pending
- 1996-04-23 BR BR9608271A patent/BR9608271A/pt unknown
- 1996-04-23 TR TR97/01288T patent/TR199701288T1/xx unknown
- 1996-04-23 NZ NZ306603A patent/NZ306603A/en unknown
- 1996-05-02 AR AR33638396A patent/AR001841A1/es unknown
-
1997
- 1997-10-20 IS IS4595A patent/IS4595A/is unknown
- 1997-10-31 NO NO975019A patent/NO975019D0/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010523238A (ja) * | 2007-04-10 | 2010-07-15 | サンド アクチエンゲゼルシャフト | 物質の経口投与のための装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW341520B (en) | 1998-10-01 |
| NO975019L (no) | 1997-10-31 |
| HUP9801947A3 (en) | 1999-04-28 |
| WO1996034681A1 (en) | 1996-11-07 |
| NZ306603A (en) | 1998-05-27 |
| SE9501631D0 (sv) | 1995-05-03 |
| SK142897A3 (en) | 1998-07-08 |
| AU5520396A (en) | 1996-11-21 |
| IS4595A (is) | 1997-10-20 |
| AU700156B2 (en) | 1998-12-24 |
| ZA963190B (en) | 1996-11-04 |
| EE9700265A (et) | 1998-04-15 |
| CN1183057A (zh) | 1998-05-27 |
| PL323157A1 (en) | 1998-03-16 |
| TR199701288T1 (xx) | 1998-02-21 |
| BR9608271A (pt) | 1999-05-11 |
| CA2218739A1 (en) | 1996-11-07 |
| CZ345697A3 (cs) | 1998-07-15 |
| KR19990008268A (ko) | 1999-01-25 |
| EP0827419A1 (en) | 1998-03-11 |
| HUP9801947A2 (hu) | 1998-12-28 |
| SE9501631L (sv) | 1996-11-04 |
| AR001841A1 (es) | 1997-12-10 |
| NO975019D0 (no) | 1997-10-31 |
| SE504683C2 (sv) | 1997-04-07 |
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